Isorbide Side Effects

Common Isorbide Side Effects

The most commonly reported Isorbide side effects (click to view or check a box to report):

Blood Triglycerides Increased (1)
Blood Sodium Decreased (1)
Blood Chloride Decreased (1)
Toxic Epidermal Necrolysis (1)
Blood Urea Increased (1)
Cardiac Failure Acute (1)
Pruritus (1)
Neutropenic Sepsis (1)
International Normalised Ratio Decreased (1)
Cardiac Failure Congestive (1)
Atrial Natriuretic Peptide Increased (1)

If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Isorbide Side Effects Reported to FDA

The following Isorbide reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

The appearance of Isorbide on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Neutropenic Sepsis, Toxic Epidermal Necrolysis
This is a report of a 57-year-old female patient (weight: NA) from UNITED KINGDOM, suffering from the following symptoms/conditions: NA, who was treated with Isorbide (dosage: NA, start time: Jul 29, 2011), combined with:
  • Ursodiol
  • Diazepam
  • Dothiepin Hydrochloride
  • Furosemide
  • Simvastatin
  • Warfarin Sodium
  • Gemcitabine Hydrochloride
  • Bisoprolol
and developed a serious reaction and side effect(s). The consumer presented with:
  • Neutropenic Sepsis
  • Toxic Epidermal Necrolysis
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isorbide treatment in female patients, resulting in neutropenic sepsis side effect. The patient was hospitalized.

Pruritus, Blood Triglycerides Increased
This report suggests a potential Isorbide Pruritus, Blood Triglycerides Increased side effect(s) that can have serious consequences. A male patient (weight: NA) from UNITED STATES was diagnosed with the following symptoms/conditions: NA and used Isorbide (dosage: NA) starting Dec 27, 1999. Soon after starting Isorbide the patient began experiencing various side effects, including:
  • Pruritus
  • Blood Triglycerides Increased
Drugs used concurrently:
  • Cozaar
  • Coumadin
  • Aspirin (In The Morning)
  • Folic Acid
  • Niaspan (At Bedtime)
  • Metoprolol Tartrate
Although Isorbide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as pruritus, may still occur.

International Normalised Ratio Decreased
This International Normalised Ratio Decreased problem was reported by a consumer or non-health professional from UNITED STATES. A 77-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Isorbide (dosage: NA). The following drugs were being taken at the same time:
  • Omeprazole
  • Centrum Silver
  • Nifedipine
  • Vitamin B-12 (Pill And Monthly Shot)
  • Novolog (1 D.f:70/30 Units Not Specified)
  • Lorazepam
  • Lisinopril
  • Warfarin Sodium
When commencing Isorbide, the patient experienced the following unwanted symptoms/side effects:
  • International Normalised Ratio Decreased
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as international normalised ratio decreased, may become evident only after a product is in use by the general population.

Atrial Natriuretic Peptide Increased, Blood Chloride Decreased, Blood Sodium Decreased, Blood Urea Increased, Cardiac Failure Acute, Cardiac Failure Congestive
This is a report of a 75-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: coronary artery disease,cardiac failure and was treated with Isorbide (dosage: 20 Mg Tid Po) starting May 01, 2006. Concurrently used drugs: NA.Soon after that, the consumer experienced the following side effects:
  • Atrial Natriuretic Peptide Increased
  • Blood Chloride Decreased
  • Blood Sodium Decreased
  • Blood Urea Increased
  • Cardiac Failure Acute
  • Cardiac Failure Congestive
The patient was hospitalized. This opens a possibility that Isorbide treatment could cause the above reactions, including atrial natriuretic peptide increased, and some female subjects may be more susceptible.

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Discuss Isorbide Side Effects

    Did You Have a Isorbide Side Effect?

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    Isorbide Safety Alerts, Active Ingredients, Usage Information

    More About Isorbide

    Side Effects reported to FDA: 4

    Isorbide safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 2

    Latest Isorbide clinical trials