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Isorbide Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Neutropenic Sepsis, Toxic Epidermal Necrolysis (7787340-3)
on Sep 23, 2011 Female from UNITED KINGDOM , 57 years of age, weighting 125.7 lb, was treated with Isorbide. Directly after, patient experienced the unwanted or unexpected Isorbide side effects: neutropenic sepsis, toxic epidermal necrolysis. Isorbide dosage: N/A.
Associated medications used:
  • Ursodiol
  • Diazepam
  • Dothiepin Hydrochloride
  • Furosemide
  • Simvastatin
  • Warfarin Sodium
  • Gemcitabine Hydrochloride
  • Bisoprolol
Patient was hospitalized.

Pruritus, Blood Triglycerides Increased (7662313-X)
Patient was taking Isorbide. Patient felt the following Isorbide side effects: pruritus, blood triglycerides increased on Dec 28, 2010 from UNITED STATES Additional patient health information: Male , weighting 285.3 lb, . Isorbide dosage: N/A.
Multiple prescriptions taken:
  • Cozaar
  • Coumadin
  • Aspirin (In The Morning)
  • Folic Acid
  • Niaspan (At Bedtime)
  • Metoprolol Tartrate


International Normalised Ratio Decreased (7632638-2)
Adverse event was reported on Nov 05, 2010 by a Female taking Isorbide (Dosage: N/A) . Location: UNITED STATES , 77 years of age, weighting 178.6 lb, After Isorbide was administered, patient encountered several Isorbide side effects: international normalised ratio decreased.
Multiple concurrent drugs taken:
  • Omeprazole
  • Centrum Silver
  • Nifedipine
  • Vitamin B-12 (Pill And Monthly Shot)
  • Novolog (1 D.f:70/30 Units Not Specified)
  • Lorazepam
  • Lisinopril
  • Warfarin Sodium


Atrial Natriuretic Peptide Increased, Blood Chloride Decreased, Blood Sodium Decreased, Blood Urea Increased, Cardiac Failure Acute, Cardiac Failure Congestive (5129489-X)
on Sep 26, 2006 Female from UNITED STATES , 75 years of age, weighting 133.0 lb, was diagnosed with
  • coronary artery disease
  • cardiac failure
and was treated with Isorbide. Directly after, patient experienced the unwanted or unexpected Isorbide side effects: atrial natriuretic peptide increased, blood chloride decreased, blood sodium decreased, blood urea increased, cardiac failure acute, cardiac failure congestive. Isorbide dosage: 20 Mg Tid Po. Patient was hospitalized.

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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Isorbide Information

More About Isorbide

Side Effects reported to FDA: 4. View Isorbide Adverse Reports

Isorbide safety alerts: No

Reported deaths: 1

Reported hospitalizations: 2

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