PatientsVille.com Logo

Isosorbide Side Effects

PatientsVille

Common Isosorbide Side Effects


The most commonly reported Isosorbide side effects (click to view or check a box to report):

Product Quality Issue (279)
Dizziness (135)
Chest Pain (85)
Hypotension (80)
Headache (69)
Fall (69)
Myocardial Infarction (65)
Dyspnoea (65)
Asthenia (64)
Blood Pressure Decreased (52)
Syncope (49)
Loss Of Consciousness (42)
Nausea (34)
Fatigue (29)
Diarrhoea (29)
Vomiting (28)
Renal Failure Acute (28)
Incorrect Dose Administered (28)
Cardiac Failure (28)
Cardiac Failure Congestive (27)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Isosorbide Side Effects Reported to FDA



Isosorbide Side Effect Report#9888536
Poisoning, Completed Suicide, Exposure Via Ingestion
This is a report of a 36-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Isosorbide Dinitrate (dosage: NA, start time: NS), combined with:
  • Amlodipine
  • Losartan
  • Metoprolol Extended Release
  • Meclizine
  • Quinine
  • Tamulosin
  • Ethanol
  • Temazepam
and developed a serious reaction and side effect(s): Poisoning, Completed Suicide, Exposure Via Ingestion after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isosorbide Dinitrate treatment in male patients, resulting in Poisoning side effect.
Isosorbide Side Effect Report#9825099
Blood Pressure Decreased
This report suggests a potential Isosorbide Dinitrate Blood Pressure Decreased side effect(s) that can have serious consequences. A 65-year-old male patient (weight: NA) from DE was diagnosed with the following symptoms/conditions: diagnostic procedure and used Isosorbide Dinitrate (dosage: NA) starting
Aug 09, 2012. After starting Isosorbide Dinitrate the patient began experiencing various side effects, including: Blood Pressure DecreasedAdditional drugs used concurrently: NA. Although Isosorbide Dinitrate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Blood Pressure Decreased, may still occur.
Isosorbide Side Effect Report#9825091
Blood Pressure Decreased
This Blood Pressure Decreased problem was reported by a pharmacist from DE. A 73-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: diagnostic procedure. On
Aug 09, 2012 this consumer started treatment with Isosorbide Dinitrate (dosage: NA). The following drugs were being taken at the same time: NA. When using Isosorbide Dinitrate, the patient experienced the following unwanted symptoms/side effects: Blood Pressure DecreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Blood Pressure Decreased, may become evident only after a product is in use by the general population.
Isosorbide Side Effect Report#9817278
This Death side effect was reported by a pharmacist from US. A 65-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Isosorbide Dinitrate (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Salicylates Nos
.After starting to take Isosorbide Dinitrate the consumer reported adverse symptoms, such as: These side effects may potentially be related to Isosorbide Dinitrate.
Isosorbide Side Effect Report#9817276
Completed Suicide
This is a report of a 39-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Isosorbide Dinitrate (dosage: NA, start time: NS), combined with:
  • Metoprolol
  • Amphetamine (Unk Unk, Ingst+inhal)
and developed a serious reaction and side effect(s): Completed Suicide after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isosorbide Dinitrate treatment in male patients, resulting in Death side effect.
Isosorbide Side Effect Report#9802960
Completed Suicide
This report suggests a potential Isosorbide Mononitrate Completed Suicide side effect(s) that can have serious consequences. A 42-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Isosorbide Mononitrate (dosage: NA) starting NS. After starting Isosorbide Mononitrate the patient began experiencing various side effects, including: Completed SuicideAdditional drugs used concurrently:
  • Metoprolol
  • Clopidogrel
The patient was hospitalized. Although Isosorbide Mononitrate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Completed Suicide, may still occur.
Isosorbide Side Effect Report#9778965
Prostate Cancer, Photosensitivity Reaction, Lip Swelling, Overdose
This Prostate Cancer problem was reported by a pharmacist from US. A 58-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: angina pectoris. On
Apr 22, 2010 this consumer started treatment with Isosorbide Mononitrate (dosage: 60 Mg 3 Tablet Once A Day). The following drugs were being taken at the same time: NA. When using Isosorbide Mononitrate, the patient experienced the following unwanted symptoms/side effects: Prostate Cancer, Photosensitivity Reaction, Lip Swelling, OverdoseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Prostate Cancer, may become evident only after a product is in use by the general population.
Isosorbide Side Effect Report#9778808
Cyanosis, Pain In Extremity, Peripheral Vascular Disorder
This Cyanosis side effect was reported by a pharmacist from US. A 10-year-old female patient (weight:NA) experienced the following symptoms/conditions: angina pectoris.The patient was prescribed Isosorbide Mononitrate (drug dosage: NA), which was initiated on
Jun 07, 2013. Concurrently used drugs:
  • Amlodipine
  • Dexamethasone
  • Docusate
  • Effexor
  • Folic Acid
  • Lasix
  • Lisinopril
  • Metoprolol
.After starting to take Isosorbide Mononitrate the consumer reported adverse symptoms, such as: Cyanosis, Pain In Extremity, Peripheral Vascular DisorderThese side effects may potentially be related to Isosorbide Mononitrate.
Isosorbide Side Effect Report#9736511
Subdural Haematoma
This is a report of a 92-year-old male patient (weight: NA) from GB, suffering from the following health symptoms/conditions: NA, who was treated with Isosorbide Mononitrate (dosage: NA, start time:
Dec 03, 2010), combined with:
  • Metformin
  • Nicorandil
and developed a serious reaction and side effect(s): Subdural Haematoma after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isosorbide Mononitrate treatment in male patients, resulting in Subdural Haematoma side effect. The patient was hospitalized.
Isosorbide Side Effect Report#9736232
Subdural Haematoma, Vascular Dementia, Delirium, Orthostatic Hypotension
This report suggests a potential Isosorbide Mononitrate Subdural Haematoma side effect(s) that can have serious consequences. A 82-year-old male patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: NA and used Isosorbide Mononitrate (dosage: NA) starting
Jul 25, 2012. After starting Isosorbide Mononitrate the patient began experiencing various side effects, including: Subdural Haematoma, Vascular Dementia, Delirium, Orthostatic HypotensionAdditional drugs used concurrently:
  • Metformin Hydrochloride (2000 Mg)
  • Nicorandil
The patient was hospitalized. Although Isosorbide Mononitrate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Subdural Haematoma, may still occur.
Isosorbide Side Effect Report#9651554
Pruritus, Erythema
This Pruritus problem was reported by a consumer or non-health professional from US. A 75-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On 1999 this consumer started treatment with Isosorbide Mononitrate Er Tablets 60mg (dosage: NA). The following drugs were being taken at the same time: NA. When using Isosorbide Mononitrate Er Tablets 60mg, the patient experienced the following unwanted symptoms/side effects: Pruritus, ErythemaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pruritus, may become evident only after a product is in use by the general population.
Isosorbide Side Effect Report#9651498
Chest Pain
This Chest Pain side effect was reported by a consumer or non-health professional from US. A 72-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Isosorbide Mononitrate Er Tablets 60mg (drug dosage: NA), which was initiated on 201108. Concurrently used drugs: NA..After starting to take Isosorbide Mononitrate Er Tablets 60mg the consumer reported adverse symptoms, such as: Chest PainThese side effects may potentially be related to Isosorbide Mononitrate Er Tablets 60mg.
Isosorbide Side Effect Report#9651487
Dizziness
This is a report of a 72-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: myocardial infarction, who was treated with Isosorbide Mononitrate Er Tablets 60mg (dosage: NA, start time: 201205), combined with: NA. and developed a serious reaction and side effect(s): Dizziness after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isosorbide Mononitrate Er Tablets 60mg treatment in female patients, resulting in Dizziness side effect.
Isosorbide Side Effect Report#9651484
Ammonia Increased, Tinnitus, Dizziness
This report suggests a potential Isosorbide Mononitrate Er Tablets 60mg Ammonia Increased side effect(s) that can have serious consequences. A 77-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: angina pectoris and used Isosorbide Mononitrate Er Tablets 60mg (dosage: NA) starting 201206. After starting Isosorbide Mononitrate Er Tablets 60mg the patient began experiencing various side effects, including: Ammonia Increased, Tinnitus, DizzinessAdditional drugs used concurrently:
  • Lisinopril Tablets
  • Plavix
Although Isosorbide Mononitrate Er Tablets 60mg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Ammonia Increased, may still occur.
Isosorbide Side Effect Report#9615002
Product Label Issue
This Product Label Issue problem was reported by a pharmacist from US. A 0-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Oct 09, 2013 this consumer started treatment with Isosorbide Mononitrate (dosage: NA). The following drugs were being taken at the same time: NA. When using Isosorbide Mononitrate, the patient experienced the following unwanted symptoms/side effects: Product Label IssueAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Product Label Issue, may become evident only after a product is in use by the general population.
Isosorbide Side Effect Report#9530781
Gallbladder Non-functioning, Prostate Cancer, Prostatic Specific Antigen Increased, Urinary Incontinence, Spondylitis, Chest Discomfort, Blood Pressure Decreased, Malaise, Somnolence
This Gallbladder Non-functioning side effect was reported by a consumer or non-health professional from US. A male patient (weight:NA) experienced the following symptoms/conditions: coronary artery dilatation.The patient was prescribed Isosorbide Mononitrate (drug dosage: 30 Mg), which was initiated on 2006. Concurrently used drugs: NA..After starting to take Isosorbide Mononitrate the consumer reported adverse symptoms, such as: Gallbladder Non-functioning, Prostate Cancer, Prostatic Specific Antigen Increased, Urinary Incontinence, Spondylitis, Chest Discomfort, Blood Pressure Decreased, Malaise, SomnolenceThese side effects may potentially be related to Isosorbide Mononitrate. The patient was hospitalized.
Isosorbide Side Effect Report#9495209
Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia
This is a report of a 68-year-old male patient (weight: NA) from IT, suffering from the following health symptoms/conditions: NA, who was treated with Isosorbide Dinitrate (dosage: 5mg;x1;sl, start time: NS), combined with:
  • Radioisotope
and developed a serious reaction and side effect(s): Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isosorbide Dinitrate treatment in male patients, resulting in Blood Pressure Decreased side effect.
Isosorbide Side Effect Report#9495195
Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia
This report suggests a potential Isosorbide Dinitrate Blood Pressure Decreased side effect(s) that can have serious consequences. A 75-year-old male patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: NA and used Isosorbide Dinitrate (dosage: 5mg;xl;sl) starting NS. After starting Isosorbide Dinitrate the patient began experiencing various side effects, including: Blood Pressure Decreased, Heart Rate Increased, Myocardial IschaemiaAdditional drugs used concurrently:
  • Radioisotope
Although Isosorbide Dinitrate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Blood Pressure Decreased, may still occur.
Isosorbide Side Effect Report#9495194
Angina Pectoris, Cardiac Failure, Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia
This Angina Pectoris problem was reported by a physician from IT. A 60-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Isosorbide Dinitrate (dosage: 5mg;x1;sl). The following drugs were being taken at the same time:
  • Thallium
When using Isosorbide Dinitrate, the patient experienced the following unwanted symptoms/side effects: Angina Pectoris, Cardiac Failure, Blood Pressure Decreased, Heart Rate Increased, Myocardial IschaemiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Angina Pectoris, may become evident only after a product is in use by the general population.
Isosorbide Side Effect Report#9495192
Angina Pectoris, Cardiac Failure, Myocardial Ischaemia, Blood Pressure Decreased, Heart Rate Increased
This Angina Pectoris side effect was reported by a physician from US. A 85-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Isosorbide Dinitrate (drug dosage: 5mg;x1;sl), which was initiated on NS. Concurrently used drugs:
  • Radioisotope
.After starting to take Isosorbide Dinitrate the consumer reported adverse symptoms, such as: Angina Pectoris, Cardiac Failure, Myocardial Ischaemia, Blood Pressure Decreased, Heart Rate IncreasedThese side effects may potentially be related to Isosorbide Dinitrate.
Isosorbide Side Effect Report#9495187
Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia
This is a report of a 65-year-old male patient (weight: NA) from IT, suffering from the following health symptoms/conditions: NA, who was treated with Isosorbide Dinitrate (dosage: 5mg;x1;sl, start time: NS), combined with:
  • Radioisotope
and developed a serious reaction and side effect(s): Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isosorbide Dinitrate treatment in male patients, resulting in Blood Pressure Decreased side effect.
Isosorbide Side Effect Report#9495183
Electrocardiogram St Segment Depression, Cardiac Failure, Heart Rate Increased, Blood Pressure Decreased, Myocardial Ischaemia
This report suggests a potential Isosorbide Dinitrate Electrocardiogram St Segment Depression side effect(s) that can have serious consequences. A 77-year-old male patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: NA and used Isosorbide Dinitrate (dosage: 5mg;x1;sl) starting NS. After starting Isosorbide Dinitrate the patient began experiencing various side effects, including: Electrocardiogram St Segment Depression, Cardiac Failure, Heart Rate Increased, Blood Pressure Decreased, Myocardial IschaemiaAdditional drugs used concurrently:
  • Radioisotope
Although Isosorbide Dinitrate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Electrocardiogram St Segment Depression, may still occur.
Isosorbide Side Effect Report#9495177
Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia
This Blood Pressure Decreased problem was reported by a physician from IT. A 86-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Isosorbide (dosage: 5mg;x1;sl). The following drugs were being taken at the same time:
  • Radioisotope
When using Isosorbide, the patient experienced the following unwanted symptoms/side effects: Blood Pressure Decreased, Heart Rate Increased, Myocardial IschaemiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Blood Pressure Decreased, may become evident only after a product is in use by the general population.
Isosorbide Side Effect Report#9495175
Blood Pressure Decreased, Heart Rate Increased, Myocardial Ischaemia
This Blood Pressure Decreased side effect was reported by a physician from IT. A 66-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Isosorbide Dinitrate (drug dosage: 5 Mg;x1;sl), which was initiated on NS. Concurrently used drugs:
  • Radioisotope
.After starting to take Isosorbide Dinitrate the consumer reported adverse symptoms, such as: Blood Pressure Decreased, Heart Rate Increased, Myocardial IschaemiaThese side effects may potentially be related to Isosorbide Dinitrate.
Isosorbide Side Effect Report#9495077
Myocardial Ischaemia
This is a report of a 54-year-old male patient (weight: NA) from IT, suffering from the following health symptoms/conditions: NA, who was treated with Isosorbide Dinitrate (dosage: 5mg;x1;sl, start time: NS), combined with:
  • Raadioisotope
and developed a serious reaction and side effect(s): Myocardial Ischaemia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Isosorbide Dinitrate treatment in male patients, resulting in Myocardial Ischaemia side effect.

1 of 37 


The appearance of Isosorbide on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Isosorbide Side Effects for Women?

Women Side EffectsReports
Product Quality Issue 135
Dizziness 65
Chest Pain 49
Dyspnoea 39
Fall 34
Headache 29
Myocardial Infarction 27
Asthenia 26
Hypotension 26
Blood Pressure Decreased 23

What are common Isosorbide Side Effects for Men?

Men Side EffectsReports
Product Quality Issue 142
Dizziness 69
Hypotension 53
Asthenia 38
Headache 38
Myocardial Infarction 38
Fall 35
Chest Pain 34
Blood Pressure Decreased 27
Syncope 27

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Isosorbide reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Isosorbide Side Effects

    Did You Have a Isosorbide Side Effect?

    Yes, Severe
    Yes, Moderate
    Yes, Minor
    No

    How Effective is Isosorbide for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective

    Isosorbide Safety Alerts, Active Ingredients, Usage Information

    NDC0143-1333
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameIsosorbide Mononitrate
    NameIsosorbide Mononitrate
    Dosage FormTABLET, COATED
    RouteORAL
    On market since20001005
    LabelerWest-ward Pharmaceutical Corp
    Active Ingredient(s)ISOSORBIDE MONONITRATE
    Strength(s)20
    Unit(s)mg/1
    Pharma Class

    Isosorbide Dosage, Warnings, Usage.

    Side Effects reported to FDA: 904

    Isosorbide safety alerts: 2008

    Reported deaths: 148

    Reported hospitalizations: 390

    Isosorbide Mononitrate Extended Release Tablets 30 mg and 60 mg

    Propafenone HCl Tablets 150 mg, 225 mg, and 300 mg
    Morphine Sulfate Extended Release Tablets 15 mg
    Morphine Sulfate Immediate Release Tablets 15 mg and 30 mg
    Dextroamphetamine Sulfate Tablets 10 mg

    Audience: Pharmacists, other healthcare professionals, patients

    [Posted 11/10/2008] Ethex Corp and FDA notified healthcare professionals of a voluntary recall of five generic products (Propafenone HCl Tablets, Isosorbide Mononitrate Extended Release Tablets, Morphine Sulfate Extended Release Tablets, Morphine Sulfate Immediate Release Tablets, and Dextroamphetamine Sulfate Tablets). The products were recalled because they may contain oversized tablets. Oversized tablets may contain more than the intended levels of the active drug ingredient that could result in patients receiving as much as twice the expected dosage of these drugs, which could cause serious or life-threatening consequences. Overdoses can include arrhythmias and low blood pressure with Propafenone HCl; fainting and low blood pressure with Isosorbide Mononitrate; respiratory depression and low blood pressure with Morphine Sulfate; and rapid heart rate and high blood pressure with Dextroamphetamine Sulfate. Patients who experience any adverse reactions to these drugs should contact their healthcare professional immediately. See the manufacturer's recall notice for specific lot numbers of the products affected by this recall.

    [November 07, 2008 - Press Release - Ethex Corp]

    Previous MedWatch Alert:
    [October 16, 2008]

    Latest Isosorbide clinical trials