Isovorin Side Effects summary

Total Isovorin reports: 35. View

Isovorin FDA safety alerts: No.

Reported deaths: 8

Reported hospitalizations: 8.

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Recently reported Isovorin Side Effects


Common Isovorin Side Effects
Leukopenia 17%
Diarrhoea 14%
Gastrointestinal perforation 11%
Neutropenia 11%
White blood cell count decreased 11%
Convulsion 9%
Disseminated intravascular coagulation 9%
Palmar-plantar erythrodysaesthesia syndrome 9%
Shock 9%
Thrombocytopenia 9%
Vomiting 9%
Alanine aminotransferase increased 6%
Aspartate aminotransferase increased 6%
Cardiac arrest  What is  Cardiac arrest                                                                                                                                                                                          6%
Fall  What is  Fall                                                                                                                                                                                                    6%
Flushing 6%
Hypertension 6%
Loss of consciousness 6%
Reversible posterior leukoencephalopathy syndrome 6%
Stomatitis 6%
Acute respiratory distress syndrome 3%
Anaphylactic shock 3%
Blood bilirubin increased 3%
Blood pressure increased 3%
Bradycardia 3%
Cardiac failure 3%
Decubitus ulcer 3%
Depressed level of consciousness 3%
Duodenal ulcer perforation 3%
Guillain-barre syndrome  What is  Guillain-barre syndrome                                                                                                                                                                                 3%
Haemoglobin decreased 3%
Haemorrhage 3%
Heart rate increased 3%
Hepatic encephalopathy 3%
Hepatic function abnormal 3%
Hyperammonaemia 3%
Ileal perforation 3%
Interstitial lung disease 3%
Intestinal fistula 3%
Intestinal perforation 3%
Jaw fracture 3%
Metabolic acidosis 3%
Myocardial ischaemia 3%
Nausea  What is  Nausea                                                                                                                                                                                                  3%
Necrotising fasciitis 3%
Pancytopenia 3%
Peritonitis 3%
Platelet count decreased 3%
Pneumonia  What is  Pneumonia                                                                                                                                                                                               3%
Rectal perforation 3%
Septic shock 3%
Stevens-johnson syndrome 3%

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Isovorin Side Effects reported on Patientsville.com

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Isovorin Side Effects reported to FDA

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Isovorin Side Effects Report #5265486-1
Health Professional from JAPAN reported Isovorin side effect on Mar 05, 2007. Male patient, 64 years of age, was diagnosed with large intestine carcinoma and was treated with Isovorin. After drug was administered, patient experienced the following side effects: convulsion. Isovorin dosage: unknown. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.



Isovorin Side Effects Report #5277600-2
Isovorin side effect was reported by a Health Professional from JAPAN on Mar 15, 2007. Female patient, weighting 99.21 lb, was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: cardiac failure. Isovorin dosage: unknown. During the same period patient was treated with DECADRON, NASEA, FLUOROURACIL, OXALIPLATIN. Patient recovered.



Isovorin Side Effects Report #5304826-1
Health Professional from JAPAN reported Isovorin side effect on Apr 12, 2007. Female patient, weighting 70.55 lb, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, haemoglobin decreased, thrombocytopenia. Isovorin dosage: unknown. During the same period patient was treated with OXALIPLATIN, KYTRIL, DECADRON, FLUOROURACIL. Patient recovered.



Isovorin Side Effects Report #5336902-1
Isovorin side effect was reported by a Health Professional from JAPAN on May 17, 2007. Female patient, weighting 121.3 lb, was diagnosed with diarrhoea, rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: duodenal ulcer perforation, leukopenia, neutropenia. Isovorin dosage: unknown. During the same period patient was treated with SOLDEM, FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.




Isovorin Side Effects Report #5080440-0
Health Professional from JAPAN reported Isovorin side effect on July 26, 2006. Male patient, 60 years of age, weighting 112.4 lb, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: bradycardia, cardiac arrest What is  cardiac arrest, depressed level of consciousness, diarrhoea, disseminated intravascular coagulation, leukopenia, metabolic acidosis, neutropenia. Isovorin dosage: unknown. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL. Patient died on 07/26/2006.



Isovorin Side Effects Report #5117842-X
Isovorin side effect was reported by a Physician from JAPAN on May 19, 2006. Female patient was diagnosed with rectal cancer, blood pressure decreased, antibiotic prophylaxis, stomach discomfort, nausea What is  nausea and was treated with Isovorin. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, leukopenia, neutropenia, pneumonia What is  pneumonia, septic shock, thrombocytopenia. Isovorin dosage: 100.8 MG/M2 ON DAYS 1 AND 2. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL, LIDOCAINE, EPINEPHRINE, IMIPENEM CILASTATIN, FAMOTIDINE, METOCLOPRAMIDE. Patient died on 03/17/2006.



Isovorin Side Effects Report #5128793-9
Physician from JAPAN reported Isovorin side effect on Aug 24, 2006. Male patient, weighting 105.8 lb, was diagnosed with large intestine carcinoma and was treated with Isovorin. After drug was administered, patient experienced the following side effects: convulsion, decubitus ulcer, fall What is  fall, hyperammonaemia, loss of consciousness. Isovorin dosage: unknown. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL. Patient recovered.



Isovorin Side Effects Report #5377223-0
Isovorin side effect was reported by a Health Professional from JAPAN on June 22, 2007. Male patient, 74 years of age, was treated with Isovorin. After drug was administered, patient experienced the following side effects: interstitial lung disease. Isovorin dosage: unknown. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL. Patient died on 06/22/2007.



Isovorin Side Effects Report #5382160-1
Health Professional from JAPAN reported Isovorin side effect on June 27, 2007. Female patient, 63 years of age, was diagnosed with large intestine carcinoma and was treated with Isovorin. After drug was administered, patient experienced the following side effects: hepatic encephalopathy. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, FLUOROURACIL. Patient recovered.




Isovorin Side Effects Report #5452746-4
Isovorin side effect was reported by a Physician from JAPAN on Sept 05, 2007. Male patient was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, fall What is  fall, jaw fracture, platelet count decreased. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, BEVACIZUMAB, OXALIPLATIN. Patient was hospitalized. Patient recovered.



Isovorin Side Effects Report #5508992-4
Health Professional from JAPAN reported Isovorin side effect on Oct 30, 2007. Male patient was diagnosed with large intestine carcinoma and was treated with Isovorin. After drug was administered, patient experienced the following side effects: pancytopenia. Isovorin dosage: 175 MG. During the same period patient was treated with FLUOROURACIL, ELPLAT. Patient recovered.



Isovorin Side Effects Report #5558100-9
Isovorin side effect was reported by a Physician from JAPAN on Dec 06, 2007. Female patient, 82 years of age, was diagnosed with large intestine carcinoma and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, leukopenia, vomiting. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, FLUOROURACIL. Patient died on 11/29/2007.



Isovorin Side Effects Report #5573192-9
Physician from JAPAN reported Isovorin side effect on Dec 13, 2007. Female patient, 82 years of age, weighting 94.80 lb, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, leukopenia, stevens-johnson syndrome, vomiting. Isovorin dosage: 125 MG/BODY=92.6 MG/M2. During the same period patient was treated with ELPLAT, FLUOROURACIL. Patient died on 11/29/2007.



Isovorin Side Effects Report #5573204-2
Isovorin side effect was reported by a Health Professional from JAPAN on Dec 14, 2007. Male patient, weighting 116.8 lb, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: blood pressure increased, convulsion, heart rate increased, loss of consciousness, nausea What is  nausea. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, FLUOROURACIL. Patient was hospitalized. Patient recovered.




Isovorin Side Effects Report #5602097-X
Health Professional from JAPAN reported Isovorin side effect on Jan 16, 2008. Female patient, 54 years of age, was diagnosed with rectal cancer metastatic and was treated with Isovorin. After drug was administered, patient experienced the following side effects: gastrointestinal perforation, peritonitis, rectal perforation. Isovorin dosage: 100 MG. During the same period patient was treated with FLUOROURACIL, AVASTIN, ELPLAT. Patient recovered.



Isovorin Side Effects Report #5633287-8
Isovorin side effect was reported by a Physician from JAPAN on Feb 15, 2008. Male patient was diagnosed with colon cancer metastatic and was treated with Isovorin. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, AVASTIN, ELPLAT. Patient was hospitalized. Patient died on 02/02/2008.



Isovorin Side Effects Report #5649521-4
Health Professional from JAPAN reported Isovorin side effect on Feb 22, 2008. Male patient, weighting 134.5 lb, was diagnosed with rectal cancer, prophylaxis of nausea and vomiting and was treated with Isovorin. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, leukopenia, necrotising fasciitis, thrombocytopenia. Isovorin dosage: 325MG/BODY = 203.1 MG/M2 IN INFUSION ON DAY 1. During the same period patient was treated with ELPLAT, SAWACILLIN, SINSERON, DECADRON, KYTRIL, FLUOROURACIL. Patient died on 11/26/2007.



Isovorin Side Effects Report #5655518-0
Isovorin side effect was reported by a Physician from JAPAN on Feb 29, 2008. Male patient, 70 years of age, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELPLAT, AVASTIN. Patient was hospitalized. Patient recovered.



Isovorin Side Effects Report #5706262-2
Health Professional from JAPAN reported Isovorin side effect on Apr 04, 2008. Female patient was treated with Isovorin. After drug was administered, patient experienced the following side effects: gastrointestinal perforation. Isovorin dosage: unknown. During the same period patient was treated with AVASTIN, ELPLAT, FLUOROURACIL. Patient recovered.




Isovorin Side Effects Report #5713133-4
Isovorin side effect was reported by a Health Professional from JAPAN on Apr 14, 2008. Female patient, 48 years of age, weighting 103.6 lb, was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: gastrointestinal perforation. Isovorin dosage: 200 MG/M2. During the same period patient was treated with DECADRON, KYTRIL, AVASTIN, FLUOROURACIL, ELPLAT. Patient recovered.



Isovorin Side Effects Report #5716523-9
Physician from JAPAN reported Isovorin side effect on Apr 16, 2008. Male patient was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: intestinal fistula. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, AVASTIN, FLUOROURACIL. Patient recovered.



Isovorin Side Effects Report #5716558-6
Isovorin side effect was reported by a Physician from JAPAN on Apr 16, 2008. Male patient, 70 years of age, was treated with Isovorin. After drug was administered, patient experienced the following side effects: intestinal perforation. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELPLAT, AVASTIN. Patient recovered.



Isovorin Side Effects Report #5761392-4
Physician from JAPAN reported Isovorin side effect on June 03, 2008. Male patient, 63 years of age, weighting 132.3 lb, was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: shock. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, AVASTIN, ELPLAT. Patient recovered.



Isovorin Side Effects Report #5767645-8
Isovorin side effect was reported by a Health Professional from JAPAN on June 04, 2008. Female patient, 43 years of age, was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, DECADRON, FLUOROURACIL. Patient was hospitalized. Patient recovered.




Isovorin Side Effects Report #5788085-1
Health Professional from JAPAN reported Isovorin side effect on June 17, 2008. Male patient, weighting 149.9 lb, was diagnosed with hypertension, rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: anaphylactic shock, myocardial ischaemia, neutropenia. Isovorin dosage: unknown. During the same period patient was treated with CALBLOCK, ELPLAT, FLUOROURACIL. Patient recovered.



Isovorin Side Effects Report #5797051-1
Isovorin side effect was reported by a Physician from JAPAN on June 26, 2008. Male patient, weighting 198.4 lb, was diagnosed with rectal cancer recurrent and was treated with Isovorin. After drug was administered, patient experienced the following side effects: haemorrhage. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCON, TRAVELMIN, ELPLAT, KYTRIL, SHAKUYAKU, URSO. Patient died on 09/28/2007.



Isovorin Side Effects Report #5810595-9
Physician from JAPAN reported Isovorin side effect on July 07, 2008. Male patient was diagnosed with colon cancer metastatic and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, palmar-plantar erythrodysaesthesia syndrome, stomatitis, white blood cell count decreased. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELPLAT, AVASTIN. Patient recovered.



Isovorin Side Effects Report #5832204-5
Isovorin side effect was reported by a Health Professional from JAPAN on July 23, 2008. Male patient, 60 years of age, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: guillain-barre syndrome What is  guillain-barre syndrome. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, FLUOROURACIL. Patient recovered.



Isovorin Side Effects Report #5837237-0
Physician from JAPAN reported Isovorin side effect on Aug 01, 2008. Male patient was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: flushing, hypertension, shock. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, AVASTIN, ELPLAT. Patient recovered.




Isovorin Side Effects Report #5848635-3
Isovorin side effect was reported by a Physician from JAPAN on Aug 12, 2008. Male patient was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: flushing, hypertension, shock. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, AVASTIN, ELPLAT. Patient recovered.



Isovorin Side Effects Report #5872292-3
Health Professional from JAPAN reported Isovorin side effect on July 03, 2008. Male patient, weighting 81.57 lb, was treated with Isovorin. After drug was administered, patient experienced the following side effects: palmar-plantar erythrodysaesthesia syndrome, white blood cell count decreased. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, BEVACIZUMAB, ELPLAT. Patient recovered.



Isovorin Side Effects Report #5885438-8
Isovorin side effect was reported by a Health Professional from JAPAN on Sept 05, 2008. Female patient, 43 years of age, was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: reversible posterior leukoencephalopathy syndrome. Isovorin dosage: unknown. During the same period patient was treated with ELPLAT, DECADRON SRC, FLUOROURACIL. Patient was hospitalized. Patient recovered.



Isovorin Side Effects Report #5922426-7
Physician from JAPAN reported Isovorin side effect on Oct 09, 2008. Male patient was diagnosed with colon cancer metastatic and was treated with Isovorin. After drug was administered, patient experienced the following side effects: diarrhoea, palmar-plantar erythrodysaesthesia syndrome, stomatitis, white blood cell count decreased. Isovorin dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELPLAT, AVASTIN. Patient recovered.



Isovorin Side Effects Report #5939042-3
Isovorin side effect was reported by a Physician from JAPAN on Oct 24, 2008. Male patient, weighting 116.8 lb, was diagnosed with rectal cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: ileal perforation. Isovorin dosage: unknown. During the same period patient was treated with AVASTIN, FLUOROURACIL, LEUCOVORIN CALCIUM, ELPLAT. Patient recovered.




Isovorin Side Effects Report #6016493-2
Physician from JAPAN reported Isovorin side effect on Dec 11, 2008. Female patient, weighting 130.1 lb, was diagnosed with colon cancer and was treated with Isovorin. After drug was administered, patient experienced the following side effects: gastrointestinal perforation, white blood cell count decreased. Isovorin dosage: 201.3 MG/M2. During the same period patient was treated with FLUOROURACIL, ELPLAT, AVASTIN. Patient recovered.





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