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Review Istin Safety Reports submitted to FDA

Total Istin reports: 12.
Istin FDA safety alerts: 2001 2002 2003 2004 2005 2006 2007 2008 .
Reported deaths: 2    Reported hospitalizations: 3.
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FDA Reported Istin Side Effects: malaise, depression, cerebrovascular accident, carotid artery bypass, glycosylated haemoglobin increased, diabetic nephropathy, albuminuria, myositis, food interaction, blood pressure increased, rectal haemorrhage.
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Istin Side Effects Report #5685265-0
Pharmacist from UNITED KINGDOM reported ISTIN problem on Mar 20, 2008. Female patient, 65 years of age, was diagnosed with hypertension and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: anxiety, panic reaction, withdrawal syndrome. ISTIN dosage: unknown. During the same period patient was treated with ENALAPRIL MALEATE, RAMIPRIL. Patient recovered.

Istin Side Effects Report #5536325-6
ISTIN problem was reported by a Pharmacist from UNITED KINGDOM on Oct 30, 2007. Female patient, 84 years of age, was diagnosed with hypertension and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: dialysis, headache. ISTIN dosage: unknown. Patient recovered.

Istin Side Effects Report #5511909-X
Pharmacist from UNITED KINGDOM reported ISTIN problem on Oct 30, 2007. Female patient, 84 years of age, was diagnosed with hypertension and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: dialysis, headache. ISTIN dosage: unknown. Patient recovered.

Istin Side Effects Report #5513369-1
ISTIN problem was reported by a Physician from IRELAND on Oct 31, 2007. Female patient, weighting 134.5 lb, was diagnosed with hypertension and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: erythromelalgia. ISTIN dosage: unknown. During the same period patient was treated with AMITRIPTYLINE, DETRUSITOL, ALPRENOLOL, ACCUPRO, ACETYLSALICYLIC ACID SRT, DALMANE. Patient recovered.

Istin Side Effects Report #5520582-6
Pharmacist from UNITED KINGDOM reported ISTIN problem on Nov 09, 2007. Male patient, 67 years of age, was diagnosed with hypertension and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: migraine, transient ischaemic attack, visual disturbance. ISTIN dosage: unknown. During the same period patient was treated with DILTIAZEM, CANDESARTAN CILEXETIL, TAMSULOSIN. Patient recovered.

Istin Side Effects Report #5473803-2
ISTIN problem was reported by a Physician from UNITED KINGDOM on Sept 20, 2007. Female patient, weighting 143.3 lb, was diagnosed with hypertension, cerebrovascular accident and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, blood urea increased, inflammation, lethargy, malaise, renal failure. ISTIN dosage: unknown. During the same period patient was treated with LEVOTHYROXINE. Patient recovered.

Istin Side Effects Report #5499988-X
Physician from IRELAND reported ISTIN problem on Oct 16, 2007. Female patient, 48 years of age, was diagnosed with hypertension and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: erythromelalgia. ISTIN dosage: unknown. During the same period patient was treated with ACETYLSALICYLIC ACID SRT, AMITRIPTYLINE, DETRUSITOL, ALPRENOLOL. Patient recovered.

Istin Side Effects Report #5502457-1
ISTIN problem was reported by a Pharmacist from UNITED KINGDOM on Oct 18, 2007. Male patient, 67 years of age, was diagnosed with hypertension and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: migraine, transient ischaemic attack, visual disturbance. ISTIN dosage: unknown. During the same period patient was treated with DILTIAZEM, CANDESARTAN CILEXETIL, TAMSULOSIN. Patient recovered.

Istin Side Effects Report #5457307-9
Physician from UNITED KINGDOM reported ISTIN problem on Sept 06, 2007. Female patient, weighting 172.0 lb, was diagnosed with transient ischaemic attack and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: carotid artery bypass, cerebrovascular accident, depression, malaise. ISTIN dosage: unknown. During the same period patient was treated with AMLODIPINE, ASPIRIN, BENDROFLUMETHIAZIDE, EZETIMIBE. Patient was hospitalized. Patient recovered.

Istin Side Effects Report #5430016-8
ISTIN problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 21, 2007. Female patient, 82 years of age, was diagnosed with transient ischaemic attack and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: carotid artery bypass, cerebrovascular accident, depression, malaise. ISTIN dosage: DAILY DOSE:5MG. Patient was hospitalized. Patient recovered.

Istin Side Effects Report #5382269-2
Physician from UNITED KINGDOM reported ISTIN problem on June 28, 2007. Female patient, 72 years of age, weighting 178.6 lb, was diagnosed with hypertension, hypothyroidism and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, food interaction. ISTIN dosage: unknown. During the same period patient was treated with GRAPEFRUIT JUICE, BENDROFLUMETHIAZIDE, LEVOTHYROXINE, LOSARTAN POTASSIUM. Patient recovered.

Istin Side Effects Report #5382269-2
ISTIN problem was reported by a Physician from UNITED KINGDOM on June 28, 2007. Female patient, 72 years of age, weighting 178.6 lb, was diagnosed with hypertension, hypothyroidism and was treated with ISTIN. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, food interaction. ISTIN dosage: unknown. During the same period patient was treated with GRAPEFRUIT JUICE, BENDROFLUMETHIAZIDE, LEVOTHYROXINE, LOSARTAN POTASSIUM. Patient recovered.


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