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Deep Vein Thrombosis (1)
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Ivabradine Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Pulmonary Oedema, Oedema Peripheral, Bradycardia, Hypotension, Nausea, Renal Failure Acute (8063136-2)
on Jan 17, 2012 Male from FRANCE , 81 years of age, was diagnosed with
  • cardiac failure
and was treated with Ivabradine. Directly after, patient experienced the unwanted or unexpected Ivabradine side effects: pulmonary oedema, oedema peripheral, bradycardia, hypotension, nausea, renal failure acute. Ivabradine dosage: 5 Mg, 1x/day.
Associated medications used:
  • Bronchodual (Unk)
  • Spiriva (Unk)
  • Allopurinol (Unk)
  • Noctran 10 (Unk)
  • Aspirin (Unk)
  • Fenofibrate (Unk)
  • Lasix
  • Digoxin (0.50 Mg, 1x/day)
Patient was hospitalized.

Neutropenia (7764563-0)
Patient was taking Ivabradine. Patient felt the following Ivabradine side effects: neutropenia on Sep 09, 2011 from FRANCE Additional patient health information: Male , 64 years of age, . Ivabradine dosage: N/A.
Multiple prescriptions taken:
  • Pantoprazole (40 Mg Daily)
  • Furosemide (Unk)
  • Spasfon
  • Perindopril Erbumine (2.5 Mg Daily)
  • Inspra (25 Mg Daily)
  • Crestor
  • Prozac (20 Mg Daily)
  • Calciparine (Unk)
Patient was hospitalized.

Dyspnoea, Pulmonary Fibrosis, Lung Disorder, Weight Decreased (7740884-2)
Adverse event was reported on Sep 01, 2011 by a Male taking Ivabradine (Dosage: 5 Mg, Qd) was diagnosed with
  • angina pectoris
and. Location: UNITED KINGDOM , 76 years of age, After Ivabradine was administered, patient encountered several Ivabradine side effects: dyspnoea, pulmonary fibrosis, lung disorder, weight decreased.
Multiple concurrent drugs taken:
  • Lansoprazole (Unk Ukn, Unk)
  • Atorvastatin (Unk Ukn, Unk)
  • Ezetimibe (Unk Ukn, Unk)
  • Felodipine (Unk Ukn, Unk)
  • Ramipril (2.5 Mg, Qd)
  • Furosemide (Unk Ukn, Unk)
  • Isosorbide Mononitrate (Unk Ukn, Unk)
  • Clopidogrel (Unk Ukn, Unk)
Patient was hospitalized and became disabled.

Bradycardia, Thrombocytopenia, Renal Failure Acute (7403121-4)
on Mar 28, 2011 Male from FRANCE , 82 years of age, was diagnosed with
  • cardiac failure
and was treated with Ivabradine. Directly after, patient experienced the unwanted or unexpected Ivabradine side effects: bradycardia, thrombocytopenia, renal failure acute. Ivabradine dosage: 5 Mg, 1x/day.
Associated medications used:
  • Budesonide/formoterol Fumarate (Unk)
  • Spiriva (Unk)
  • Allopurinol (Unk)
  • Digoxin (0.50 Milligram(s), Daily)
  • Acetaminophen (Unk)
  • Xyzal (Unk)
  • Cordarone (200 Milligram(s);daily)
  • Noctran 10 (Unk)
Patient was hospitalized.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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