PatientsVille.com Logo

Januvia Side Effects

PatientsVille

Common Januvia Side Effects


The most commonly reported Januvia side effects (click to view or check a box to report):

Blood Glucose Increased (692)
Pancreatitis (591)
Hypoglycaemia (475)
Headache (432)
Nausea (376)
Diarrhoea (333)
Dizziness (309)
Rash (276)
Pancreatic Carcinoma (236)
Dyspnoea (214)
Weight Decreased (211)
Rhinorrhoea (203)
Oedema Peripheral (202)
Vomiting (193)
Fatigue (189)
Pruritus (187)
Pancreatitis Acute (181)
Abdominal Pain (178)
Renal Failure Acute (176)
Asthenia (170)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Januvia Side Effects Reported to FDA



Januvia Side Effect Report#9999212
Heart Rate Increased, Tremor, Asthenopia
This is a report of a 52-year-old female patient (weight: NA) from IN, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Januvia (dosage: 100 Mg, Qd, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Heart Rate Increased, Tremor, Asthenopia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Januvia treatment in female patients, resulting in Heart Rate Increased side effect.
Januvia Side Effect Report#9998497
Blood Glucose Increased
This report suggests a potential Januvia Blood Glucose Increased side effect(s) that can have serious consequences. A 40-year-old female patient (weight: NA) from IN was diagnosed with the following symptoms/conditions: diabetes mellitus and used Januvia (dosage: 1/day) starting NS. After starting Januvia the patient began experiencing various side effects, including: Blood Glucose IncreasedAdditional drugs used concurrently: NA.The patient was hospitalized. Although Januvia demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Blood Glucose Increased, may still occur.
Januvia Side Effect Report#9995911
Pancreatitis
This Pancreatitis problem was reported by a consumer or non-health professional from US. A 60-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus. On NS this consumer started treatment with Januvia (dosage: 100 Mg, Unk). The following drugs were being taken at the same time:
  • Metformin
When using Januvia, the patient experienced the following unwanted symptoms/side effects: PancreatitisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pancreatitis, may become evident only after a product is in use by the general population.
Januvia Side Effect Report#9993649
Pancreatic Carcinoma
This Pancreatic Carcinoma side effect was reported by a consumer or non-health professional from US. A 70-year-old male patient (weight:NA) experienced the following symptoms/conditions: diabetes mellitus.The patient was prescribed Januvia (drug dosage: NA), which was initiated on 2010. Concurrently used drugs: NA..After starting to take Januvia the consumer reported adverse symptoms, such as: Pancreatic CarcinomaThese side effects may potentially be related to Januvia.
Januvia Side Effect Report#9989898
Alopecia
This is a report of a 41-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Januvia (dosage: Unk, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Alopecia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Januvia treatment in female patients, resulting in Alopecia side effect.
Januvia Side Effect Report#9988694
This report suggests a potential Januvia Death side effect(s) that can have serious consequences. A 72-year-old male patient (weight: NA) from IN was diagnosed with the following symptoms/conditions: NA and used Januvia (dosage: 100 Mg, 1 Tab, Qd) starting NS. After starting Januvia the patient began experiencing various side effects, including:Additional drugs used concurrently: NA. Although Januvia demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Death, may still occur.
Januvia Side Effect Report#9988588
Accident, Limb Operation
This Accident problem was reported by a consumer or non-health professional from IN. A 47-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Januvia (dosage: 1 Df, Qd). The following drugs were being taken at the same time: NA. When using Januvia, the patient experienced the following unwanted symptoms/side effects: Accident, Limb OperationAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Accident, may become evident only after a product is in use by the general population.
Januvia Side Effect Report#9984744
Tubulointerstitial Nephritis, Renal Failure Acute, Osteoarthritis, Seborrhoeic Keratosis, Diabetic Retinopathy, Urinary Incontinence
This Tubulointerstitial Nephritis side effect was reported by a consumer or non-health professional from GB. A 81-year-old male patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Januvia (drug dosage: Unk), which was initiated on
Mar 05, 2013. Concurrently used drugs:
  • Prednisolone (30mg Daily)
  • Simvastatin (1 Tablet Daily, One At Night, 56 Tablet)
  • Amlodipine (10 Mg Daily)
  • Hydroxyzine Hydrochloride (25mg Daily)
  • Omeprazole (20 Mg Daily, One Tablet Daily, 28 Capsule)
  • Doxazosin Mesylate (2 Mg, Bid, Take One Daily, 56 Tablet)
  • Gliclazide (160 Mg, Bid, Two Morning Two Evening, 224 Tablet)
  • Humulin I (2 Pre-filled Disposable Injection)
.After starting to take Januvia the consumer reported adverse symptoms, such as: Tubulointerstitial Nephritis, Renal Failure Acute, Osteoarthritis, Seborrhoeic Keratosis, Diabetic Retinopathy, Urinary IncontinenceThese side effects may potentially be related to Januvia.
Januvia Side Effect Report#9980619
Macular Oedema, Hepatic Steatosis
This is a report of a 53-year-old male patient (weight: NA) from IN, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Januvia (dosage: 50 Mg, Qd, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Macular Oedema, Hepatic Steatosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Januvia treatment in male patients, resulting in Macular Oedema side effect. The patient was hospitalized.
Januvia Side Effect Report#9980380
Myocardial Infarction, Cardiac Arrest
This report suggests a potential Januvia Myocardial Infarction side effect(s) that can have serious consequences. A 58-year-old female patient (weight: NA) from PH was diagnosed with the following symptoms/conditions: NA and used Januvia (dosage: 50 Mg, One Tablet, Once A Day) starting
Aug 04, 2012. After starting Januvia the patient began experiencing various side effects, including: Myocardial Infarction, Cardiac ArrestAdditional drugs used concurrently: NA. Although Januvia demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Myocardial Infarction, may still occur.
Januvia Side Effect Report#9976028
Gastric Disorder, Dyspepsia, Pain, Paraesthesia
This Gastric Disorder problem was reported by a consumer or non-health professional from IN. A 51-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus. On NS this consumer started treatment with Januvia (dosage: 1x/day). The following drugs were being taken at the same time: NA. When using Januvia, the patient experienced the following unwanted symptoms/side effects: Gastric Disorder, Dyspepsia, Pain, ParaesthesiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Gastric Disorder, may become evident only after a product is in use by the general population.
Januvia Side Effect Report#9972678
Spondylitis, Hypoaesthesia, Arthropathy
This Spondylitis side effect was reported by a consumer or non-health professional from IN. A 48-year-old male patient (weight:NA) experienced the following symptoms/conditions: diabetes mellitus.The patient was prescribed Januvia (drug dosage: 100 Mg 1x/day), which was initiated on NS. Concurrently used drugs: NA..After starting to take Januvia the consumer reported adverse symptoms, such as: Spondylitis, Hypoaesthesia, ArthropathyThese side effects may potentially be related to Januvia.
Januvia Side Effect Report#9972303
Blood Glucose Abnormal, Vision Blurred, Body Temperature Decreased, Feeling Cold
This is a report of a 62-year-old male patient (weight: NA) from IN, suffering from the following health symptoms/conditions: NA, who was treated with Januvia (dosage: 1/day, start time: NS), combined with:
  • Insulin
and developed a serious reaction and side effect(s): Blood Glucose Abnormal, Vision Blurred, Body Temperature Decreased, Feeling Cold after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Januvia treatment in male patients, resulting in Blood Glucose Abnormal side effect.
Januvia Side Effect Report#9972089
Nausea, Pancreatic Neuroendocrine Tumour
This report suggests a potential Januvia Nausea side effect(s) that can have serious consequences. A 54-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: diabetes mellitus and used Januvia (dosage: 2 Pills, Twice Daily, Taken By Mouth) starting
Jan 05, 2009. After starting Januvia the patient began experiencing various side effects, including: Nausea, Pancreatic Neuroendocrine TumourAdditional drugs used concurrently: NA.The patient was hospitalized and became disabled. Although Januvia demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nausea, may still occur.
Januvia Side Effect Report#9970159
Muscle Rupture
This Muscle Rupture problem was reported by a health professional from FR. A 63-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On 2010 this consumer started treatment with Januvia (dosage: 1 Df, Qd). The following drugs were being taken at the same time:
  • Xarelto (20 Mg, Qd)
  • Simvastatin (20 Mg, Qd)
  • Nisisco (1 Df, Qd)
  • Cordarone (200 Mg, Qd)
  • Mediatensyl (120 Mg, Qd)
  • Hemigoxine Nativelle (0.125 Mg, Qd)
  • Stagid (2100 Mg, Qd)
When using Januvia, the patient experienced the following unwanted symptoms/side effects: Muscle RuptureAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Muscle Rupture, may become evident only after a product is in use by the general population.
Januvia Side Effect Report#9969625
Complication Of Delivery, Exposure During Pregnancy
This Complication Of Delivery side effect was reported by a health professional from FR. A 38-year-old female patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Januvia (drug dosage: Unk), which was initiated on NS. Concurrently used drugs:
  • Amarel (Unk)
  • Metformin (Unk)
.After starting to take Januvia the consumer reported adverse symptoms, such as: Complication Of Delivery, Exposure During PregnancyThese side effects may potentially be related to Januvia.
Januvia Side Effect Report#9969597
Cleft Lip And Palate, Foetal Exposure During Pregnancy
This is a report of a male patient (weight: NA) from FR, suffering from the following health symptoms/conditions: type 2 diabetes mellitus, who was treated with Januvia (dosage: Unk, start time: NS), combined with:
  • Amarel (Unk)
  • Metformin (Unk)
and developed a serious reaction and side effect(s): Cleft Lip And Palate, Foetal Exposure During Pregnancy after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Januvia treatment in male patients, resulting in Cleft Lip And Palate side effect. The patient was hospitalized.
Januvia Side Effect Report#9964771
Cerebellar Infarction, Pneumonia
This report suggests a potential Januvia Tablets 50mg Cerebellar Infarction side effect(s) that can have serious consequences. A 75-year-old male patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus and used Januvia Tablets 50mg (dosage: 50 Mg, Qd) starting
Nov 02, 2011. After starting Januvia Tablets 50mg the patient began experiencing various side effects, including: Cerebellar Infarction, PneumoniaAdditional drugs used concurrently: NA.The patient was hospitalized and became disabled. Although Januvia Tablets 50mg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cerebellar Infarction, may still occur.
Januvia Side Effect Report#9958520
Loss Of Consciousness, Pneumonia, Hypoglycaemia, Respiratory Disorder, Decreased Appetite
This Loss Of Consciousness problem was reported by a consumer or non-health professional from JP. A 86-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus. On 2013 this consumer started treatment with Januvia Tablets 50mg (dosage: 50 Mg, Qd). The following drugs were being taken at the same time:
  • Rozerem (8 Mg, Qd)
  • Sennosides (12 Mg, Bid)
  • Memary (20 Mg, Qd)
  • Magnesium Oxide (2 G, Bid)
  • Acecol (2 Mg, Qd)
  • Aricept D (10 Mg, Qd)
  • Takepron (15 Mg, Qd)
  • Opalmon (5 Mg, Bid)
When using Januvia Tablets 50mg, the patient experienced the following unwanted symptoms/side effects: Loss Of Consciousness, Pneumonia, Hypoglycaemia, Respiratory Disorder, Decreased AppetiteThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Loss Of Consciousness, may become evident only after a product is in use by the general population.
Januvia Side Effect Report#9949330
Abdominal Pain
This Abdominal Pain side effect was reported by a physician from US. A 68-year-old male patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Januvia (drug dosage: 100 Mg, Qd), which was initiated on 201401. Concurrently used drugs:
  • Metformin (1000 Mg, Bid)
.After starting to take Januvia the consumer reported adverse symptoms, such as: Abdominal PainThese side effects may potentially be related to Januvia. The patient was hospitalized.
Januvia Side Effect Report#9948806
Pancreatitis Chronic
This is a report of a 53-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: type 2 diabetes mellitus, who was treated with Januvia (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Pancreatitis Chronic after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Januvia treatment in female patients, resulting in Pancreatitis Chronic side effect. The patient was hospitalized.
Januvia Side Effect Report#9942329
Hypoglycaemia
This report suggests a potential Januvia Tablets 100mg Hypoglycaemia side effect(s) that can have serious consequences. A 84-year-old male patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus and used Januvia Tablets 100mg (dosage: NA) starting NS. After starting Januvia Tablets 100mg the patient began experiencing various side effects, including: HypoglycaemiaAdditional drugs used concurrently:
  • Glimepiride
  • Glimepiride (0.5 Mg, Daily)
  • Voglibose
  • Insulin
Although Januvia Tablets 100mg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypoglycaemia, may still occur.
Januvia Side Effect Report#9938162
Pancreatitis, Rash, Abdominal Pain
This Pancreatitis problem was reported by a consumer or non-health professional from US. A 74-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus. On NS this consumer started treatment with Januvia (dosage: Unk). The following drugs were being taken at the same time:
  • Metformin (100 Mg, Bid)
  • Lantus (24 Iu, Hs)
  • Synthroid (Unk)
  • Avapro (Unk)
  • Pravastatin Sodium (Unk)
When using Januvia, the patient experienced the following unwanted symptoms/side effects: Pancreatitis, Rash, Abdominal PainAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pancreatitis, may become evident only after a product is in use by the general population.
Januvia Side Effect Report#9937412
Pancreatitis, Pancreatitis
This Pancreatitis side effect was reported by a consumer or non-health professional from US. A 46-year-old male patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Januvia (drug dosage: Unk), which was initiated on NS. Concurrently used drugs:
  • Lantus (35 Df, Bid)
  • Novolog
  • Glipizide (5 Mg, Bid)
  • Metformin (1000 Mg, Bid)
.After starting to take Januvia the consumer reported adverse symptoms, such as: Pancreatitis, PancreatitisThese side effects may potentially be related to Januvia. The patient was hospitalized.
Januvia Side Effect Report#9937100
Glomerular Filtration Rate Decreased
This is a report of a 81-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Januvia (dosage: 100 Mg, Qd, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Glomerular Filtration Rate Decreased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Januvia treatment in female patients, resulting in Glomerular Filtration Rate Decreased side effect.


1 of 370 


The appearance of Januvia on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

300x250 Start Your Diet Today
These healthy diet meal plans are based on the science of what your body needs to lose fat and maintain a lifetime commitment to health. With bistroMD you will enjoy delicious recipes prepared with the right ingredients so that you can learn how to lose weight the healthy way and also rediscover the enjoyment of eating.

What are common Januvia Side Effects for Women?

Women Side EffectsReports
Blood Glucose Increased 404
Pancreatitis 300
Headache 283
Nausea 265
Hypoglycaemia 261
Diarrhoea 197
Dizziness 176
Rash 153
Dyspnoea 145
Vomiting 130

What are common Januvia Side Effects for Men?

Men Side EffectsReports
Blood Glucose Increased 286
Pancreatitis 285
Hypoglycaemia 212
Headache 146
Diarrhoea 134
Dizziness 132
Rash 122
Pancreatic Carcinoma 117
Nausea 110
Pancreatitis Acute 103

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Januvia reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Januvia Side Effects

    Did You Have a Januvia Side Effect?

    Yes, Severe
    Yes, Moderate
    Yes, Minor
    No

    How Effective is Januvia for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective

    Januvia Safety Alerts, Active Ingredients, Usage Information

    NDC0006-0112
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameJANUVIA
    Namesitagliptin
    Dosage FormTABLET, FILM COATED
    RouteORAL
    On market since20061016
    LabelerMerck Sharp & Dohme Corp.
    Active Ingredient(s)SITAGLIPTIN PHOSPHATE
    Strength(s)50
    Unit(s)mg/1
    Pharma ClassDipeptidyl Peptidase 4 Inhibitor [EPC],Dipeptidyl Peptidase 4 Inhibitors [MoA]

    Januvia Dosage, Warnings, Usage.

    Side Effects reported to FDA: 9243

    Januvia safety alerts: 2009

    Reported deaths: 610

    Reported hospitalizations: 3161

    Sitagliptin (marketed as Januvia and Janumet) - acute pancreatitis

    Audience: Diabetes healthcare professionals, patients

    [Posted 09/25/2009] FDA notified healthcare professionals and patients of revisions to the prescribing information for Januvia (sitagliptin) and Janumet (sitagliptin/metformin) to include information on reported cases of acute pancreatitis in patients using these products. Eighty-eight post-marketing cases of acute pancreatitis, including two cases of hemorrhagic or necrotizing pancreatitis in patients using sitagliptin, were reported to the Agency between October 2006 and February 2009. It is recommended that healthcare professionals monitor patients carefully for the development of pancreatitis after initiation or dose increases of sitagliptin or sitagliptin/metformin. Sitagliptin has not been studied in patients with a history of pancreatitis. Therefore, it is not known whether these patients are at an increased risk for developing pancreatitis and the medication should be used with caution and with appropriate monitoring in patients with a history of pancreatitis. Considerations for healthcare professionals, information for patients, and a Data Summary are provided.

    [09/25/2009 - Information for Healthcare Professionals - FDA]

    Latest Januvia clinical trials