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Constipation (2)
Entire Body Itching (1)
Hallucinations (1)
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Kadian Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 146 

(6631035-6)
on Feb 25, 2010 Male from UNITED STATES , 35 years of age, was diagnosed with
  • pain
and was treated with Kadian. . Kadian dosage: 20 Mg, 2 In 1 D, Per Oral.

(6539280-5)
Patient was taking Kadian. on Jan 06, 2010 from UNITED STATES Additional patient health information: Male , 40 years of age, was diagnosed with
  • pain
and. Kadian dosage: 20 Mg, 2 In 1 D, Per Oral.

Blood Chloride Increased, Blood Creatine Phosphokinase Increased, Body Temperature Increased, Convulsion, Electrocardiogram Qt Prolonged, Electrocardiogram St Segment Abnormal, Hypertension (6522619-4)
Adverse event was reported on Dec 11, 2009 by a Male taking Kadian (Dosage: N/A) . Location: UNITED STATES , 27 years of age, After Kadian was administered, patient encountered several Kadian side effects: blood chloride increased, blood creatine phosphokinase increased, body temperature increased, convulsion, electrocardiogram qt prolonged, electrocardiogram st segment abnormal, hypertension.
Multiple concurrent drugs taken:
  • Oxycodone Hcl
  • Ultram
  • Duloxetine Hydrochloride
  • Phencyclidine Hydrochloride
  • Muscle Relaxants
  • Anticonvulsant
  • Phencyclidine
Patient was hospitalized.

Blood Chloride Increased, Blood Creatine Phosphokinase Increased, Body Temperature Increased, Convulsion, Electrocardiogram Qt Prolonged, Hypertension, Hypotension, Lung Consolidation (6389741-7)
on Sep 22, 2009 Male from UNITED STATES , 27 years of age, was treated with Kadian. Directly after, patient experienced the unwanted or unexpected Kadian side effects: blood chloride increased, blood creatine phosphokinase increased, body temperature increased, convulsion, electrocardiogram qt prolonged, hypertension, hypotension, lung consolidation. Kadian dosage: N/A.
Associated medications used:
  • Oxycodone Hcl
  • Ultram
  • Duloxetine Hydrochloride
  • Phencyclidine Hydrochloride
  • Muscle Relaxants
  • Anticonvulsant
Patient was hospitalized.


Product Quality Issue, Respiratory Depression (6347554-6)
on Sep 09, 2009 Female from UNITED STATES , 50 years of age, weighting 180.0 lb, was diagnosed with
  • pain
and was treated with Kadian. Patient felt the following Kadian side effects: product quality issue, respiratory depression. Kadian dosage: 30mg Twice Daily Po. Patient was hospitalized.

Product Label Issue (6346866-X)
Patient was taking Kadian. After Kadian was administered, patient encountered several Kadian side effects: product label issue on Sep 08, 2009 from UNITED STATES Additional patient health information: Male , 59 years of age, was diagnosed with
  • pain
and. Kadian dosage: One Tab Daily Po.
Multiple concurrent drugs taken:
  • Er Morphine Sulfate 15 (Three Tabs Twice Daily Po)


Headache, Myoclonus, Overdose, Somnolence, Vomiting (6339408-6)
Adverse event was reported on Dec 01, 2008 by a Female taking Kadian (Dosage: 20 Mg, 2 In 1 D, Per Oral : 300 Mg, Qhs, Per Oral) was diagnosed with
  • back pain
  • depression
and. Location: UNITED STATES , 49 years of age, weighting 140.0 lb, Directly after, patient experienced the unwanted or unexpected Kadian side effects: headache, myoclonus, overdose, somnolence, vomiting. Patient was hospitalized.

Accidental Overdose, Respiratory Depression, Somnolence (6339394-9)
on Sep 22, 2008 Female from UNITED STATES , 64 years of age, weighting 140.0 lb, was diagnosed with
  • back pain
and was treated with Kadian. Patient felt the following Kadian side effects: accidental overdose, respiratory depression, somnolence. Kadian dosage: 200 Mg, 1 In 8 Hr, Oral.
Multiple prescriptions taken:
  • Oxycontin
  • Levoxyl
  • Vytorin 1/20
  • Combivent
Patient was hospitalized.

Asthma, Confusional State, Constipation, Somnolence (6339377-9)
on May 11, 2009 Female from UNITED STATES , 61 years of age, weighting 182.0 lb, was diagnosed with
  • pain
and was treated with Kadian. After Kadian was administered, patient encountered several Kadian side effects: asthma, confusional state, constipation, somnolence. Kadian dosage: 60 Mg, 1 In 12 Hr, Per Oral.
Multiple concurrent drugs taken:
  • Norco
  • Advair Diskus 100/50
Patient was hospitalized.

Constipation, Inadequate Analgesia (6268863-5)
Patient was taking Kadian. Directly after, patient experienced the unwanted or unexpected Kadian side effects: constipation, inadequate analgesia on Jul 09, 2009 from UNITED STATES Additional patient health information: Female , 85 years of age, weighting 250.0 lb, was diagnosed with
  • spinal compression fracture
  • pain
  • upper limb fracture
and. Kadian dosage: 100mg Qd Po.
Associated medications used:
  • Morphine Sulfate (60mg Bid Po)
  • Morphine Sulfate (60mg Bid Po)


Agitation, Aspiration, Depressed Level Of Consciousness, Hypercapnia, Hypotension, Pneumonia, Post Procedural Complication, Respiratory Failure (6163737-2)
Adverse event was reported on Apr 20, 2009 by a Female taking Kadian (Dosage: 200mg Bid Po) was diagnosed with
  • pain
and. Location: UNITED STATES , 46 years of age, weighting 314.4 lb, Patient felt the following Kadian side effects: agitation, aspiration, depressed level of consciousness, hypercapnia, hypotension, pneumonia, post procedural complication, respiratory failure.
Multiple prescriptions taken:
  • Metformin Hcl
  • Ibuprofen
  • Lyrica
  • Prevacid
  • Wellbutrin Xl
  • Actos
  • Cymbalta
  • Singulair
Patient was hospitalized.

Anxiety, Constipation, Depression, Diarrhoea, Gastrointestinal Disorder, Hypophagia, Insomnia, Malaise, Nausea (6109348-6)
on Mar 06, 2009 Female from UNITED STATES , 66 years of age, weighting 130.0 lb, was diagnosed with
  • fibromyalgia
  • osteoarthritis
and was treated with Kadian. After Kadian was administered, patient encountered several Kadian side effects: anxiety, constipation, depression, diarrhoea, gastrointestinal disorder, hypophagia, insomnia, malaise, nausea. Kadian dosage: 60 Mg 2/day Po. Patient was hospitalized and became disabled.

Abdominal Pain, Dyspepsia, Impaired Gastric Emptying (6105253-X)
on Feb 17, 2009 Male from UNITED STATES , 48 years of age, was diagnosed with
  • pain
and was treated with Kadian. Directly after, patient experienced the unwanted or unexpected Kadian side effects: abdominal pain, dyspepsia, impaired gastric emptying. Kadian dosage: 30 Mg, 1 In 12 Hr, Oral.
Associated medications used:
  • Fentanyl Transdermal System (100 Mcg, 1 In 3 D, Transdermal)
  • Percocet
  • Elavil
  • Ultram
  • Neurontin
  • Vasotec
  • Marijuana
Patient was hospitalized.

Cardiac Disorder, Cardiac Hypertrophy, Cor Pulmonale, Dilatation Ventricular, Hepatic Congestion, Lung Disorder, Nephrosclerosis, Pneumoconiosis, Pulmonary Congestion (6075192-1)
Patient was taking Kadian. Patient felt the following Kadian side effects: cardiac disorder, cardiac hypertrophy, cor pulmonale, dilatation ventricular, hepatic congestion, lung disorder, nephrosclerosis, pneumoconiosis, pulmonary congestion on Jan 29, 2009 from UNITED STATES Additional patient health information: Female , 49 years of age, weighting 146.0 lb, was diagnosed with
  • back pain
and. Kadian dosage: 30 Mg, 1 In 12 Hr, Oral.
Multiple prescriptions taken:
  • Mobic (7.5 Mg, 1 In 24 Hr, Oral)
  • Dilantin


Amnesia, Aortic Aneurysm, Convulsion, Electroencephalogram Abnormal, Melaena, Staring, Unresponsive To Stimuli, Upper Limb Fracture, Victim Of Abuse (6071756-X)
Adverse event was reported on Feb 09, 2009 by a Female taking Kadian (Dosage: 100 Mgm Q12 Hour Oral Mouth) was diagnosed with
  • fibromyalgia
and. Location: UNITED STATES , weighting 112.0 lb, After Kadian was administered, patient encountered several Kadian side effects: amnesia, aortic aneurysm, convulsion, electroencephalogram abnormal, melaena, staring, unresponsive to stimuli, upper limb fracture, victim of abuse.
Multiple concurrent drugs taken:
  • Oxycontin (30 Mgm Q6 Hour Prn Oral Mouth)


Chills, Heart Rate Increased, Hyperhidrosis, Pain (6037512-3)
on Dec 29, 2008 Male from UNITED STATES , 51 years of age, weighting 280.0 lb, was diagnosed with
  • back pain
and was treated with Kadian. Directly after, patient experienced the unwanted or unexpected Kadian side effects: chills, heart rate increased, hyperhidrosis, pain. Kadian dosage: 1 In 12 Hr, Oral.
Associated medications used:
  • Hydrocodone Bitartrate
  • Atenolol
  • Verapamil
  • Furosemide
  • Lisinopril
  • Zetia


(5958910-X)
on Nov 03, 2008 Female from UNITED STATES , 49 years of age, was diagnosed with
  • back pain
and was treated with Kadian. . Kadian dosage: 30 Mg, 1 In 12 Hr, Oral.
Multiple prescriptions taken:
  • Mobic (7.5 Mg,1 In 24 Hr,oral)


Ataxia, Condition Aggravated, Convulsion, Dependence, Fall, Hallucination, Overdose (5914478-5)
Patient was taking Kadian. After Kadian was administered, patient encountered several Kadian side effects: ataxia, condition aggravated, convulsion, dependence, fall, hallucination, overdose on Sep 22, 2008 from UNITED STATES Additional patient health information: Female , 44 years of age, . Kadian dosage: N/A.
Multiple concurrent drugs taken:
  • Actiq (400 Mcg, Prn, Bu)
  • Percocet
  • Duragesic-100 (150 Mcg, Hourly, Transdermal)
  • Gabitril
  • Topamax
  • Lexapro
Patient was hospitalized.

Atelectasis, Bronchial Secretion Retention, Contusion, Ecchymosis, Excoriation, Haematoma, Head Injury (5903345-9)
Adverse event was reported on Sep 12, 2008 by a Female taking Kadian (Dosage: 1 Cap Bid, Per Oral) was diagnosed with
  • back pain
and. Location: UNITED STATES , 45 years of age, weighting 126.0 lb, Directly after, patient experienced the unwanted or unexpected Kadian side effects: atelectasis, bronchial secretion retention, contusion, ecchymosis, excoriation, haematoma, head injury.
Associated medications used:
  • Percocet (1 Tab Q4-6h Prn, Per Oral)
  • Trazodone Hcl (1 Tab Qhs, Per Oral)
  • Zolpidem
  • Meprobamate
  • Promethazine
  • Ondansetron
  • Ranitidine
  • Klonopin (1 Tab Tid, Per Oral)


Dizziness, Hypotension, Overdose (5899253-2)
on May 22, 2008 Male from UNITED STATES , 49 years of age, was diagnosed with
  • back pain
and was treated with Kadian. Patient felt the following Kadian side effects: dizziness, hypotension, overdose. Kadian dosage: 20 Mg, 1 Cap Bid, Per Oral.
Multiple prescriptions taken:
  • Celebrex
  • Elavil
  • Lyrica
Patient was hospitalized.

Abnormal Behaviour, Dental Caries, Depression, Dysarthria, Tooth Abscess (5899248-9)
on Apr 08, 2008 Female from UNITED STATES , 49 years of age, weighting 135.0 lb, was diagnosed with
  • back pain
and was treated with Kadian. After Kadian was administered, patient encountered several Kadian side effects: abnormal behaviour, dental caries, depression, dysarthria, tooth abscess. Kadian dosage: 100 Mg, 1 Cap Bid.
Multiple concurrent drugs taken:
  • Actiq (800 Mcg, Oromucosal Use)
  • Lorcet-hd (Per Oral)
  • Norco (Per Oral)
  • Norco (20 Mg Q4h)
  • Oxycontin (140 Mg Daily)
  • Oxycontin (100 Mg Daily)
  • Roxicet
  • Stadol (10 Mg, Nasal)


Overdose (5899219-2)
Patient was taking Kadian. Directly after, patient experienced the unwanted or unexpected Kadian side effects: overdose on Mar 13, 2008 from UNITED STATES Additional patient health information: Male , 40 years of age, weighting 120.0 lb, . Kadian dosage: 100 Mg, 1 Cap Bid, Per Oral.
Associated medications used:
  • Oxycodone Hcl
  • Prevacid
  • Asacol
  • Lorazepam
  • Diovan 320/12.5
Patient was hospitalized.

Lethargy, Nausea, Overdose (5899216-7)
Adverse event was reported on Oct 24, 2007 by a Male taking Kadian (Dosage: 30 Capsules, Once, Per Oral) was diagnosed with
  • back pain
and. Location: UNITED STATES , 57 years of age, weighting 200.0 lb, Patient felt the following Kadian side effects: lethargy, nausea, overdose. Patient was hospitalized.

Gastrointestinal Motility Disorder, Overdose, Oxygen Saturation Decreased, Respiratory Depression, Respiratory Rate Increased, Sedation, Toxicologic Test Abnormal (5899143-5)
on Jan 28, 2008 Male from UNITED STATES , child 2 years of age, was treated with Kadian. After Kadian was administered, patient encountered several Kadian side effects: gastrointestinal motility disorder, overdose, oxygen saturation decreased, respiratory depression, respiratory rate increased, sedation, toxicologic test abnormal. Kadian dosage: N/A.
Multiple concurrent drugs taken:
  • Valproate Sodium
  • Acetaminophen And Codeine Phosphate
  • Acetaminophen And Codeine Phosphate
Patient was hospitalized.

Acute Respiratory Failure, Coma, Suicide Attempt (5899118-6)
on Jan 28, 2008 Female from UNITED STATES , 15 years of age, was treated with Kadian. Directly after, patient experienced the unwanted or unexpected Kadian side effects: acute respiratory failure, coma, suicide attempt. Kadian dosage: N/A. Patient was hospitalized.

Showing 1-25 of 146 

Kadian Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Kadian Information

Alternative KADIAN Names:MORPHINE

Active Ingredient: MORPHINE

Kadian Dosage, Warnings, Usage.

Side Effects reported to FDA: 146. View Kadian Adverse Reports

Kadian safety alerts: No

Reported deaths: 57

Reported hospitalizations: 64

Managing Your Medicines

Tips for Taking Medicines Properly

Before Taking Kadian

Find Out How to Take Kadian

Did You Have a Kadian Side Effect?

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How Effective is Kadian for You?

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