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Karvezide Side Effects

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Common Karvezide Side Effects


The most commonly reported Karvezide side effects (click to view or check a box to report):

Hyponatraemia (9)
Dizziness (5)
Renal Failure Acute (5)
Fall (5)
Hypokalaemia (4)
Hypotension (4)
Vomiting (4)
Nausea (4)
Gastroenteritis (3)
Lactic Acidosis (3)
Staphylococcal Infection (3)
Upper Limb Fracture (3)
Guillain-barre Syndrome (3)
Suicidal Ideation (3)
Somnolence (2)
Olfactory Nerve Disorder (2)
Cold Type Haemolytic Anaemia (2)
Paraesthesia (2)
Malaise (2)
Pulmonary Oedema (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Karvezide Side Effects Reported to FDA



Karvezide Side Effect Report#9858714
Hyponatraemia, Asthenia, Urticaria
This is a report of a 74-year-old male patient (weight: NA) from IT, suffering from the following health symptoms/conditions: hypertension, who was treated with Karvezide (dosage: NA, start time:
Dec 08, 2013), combined with:
  • Acetylsalicylic Acid
  • Nebilox (Strength: 5 Mg)
  • Crestor
and developed a serious reaction and side effect(s): Hyponatraemia, Asthenia, Urticaria after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Karvezide treatment in male patients, resulting in Hyponatraemia side effect. The patient was hospitalized.
Karvezide Side Effect Report#9834534
Loss Of Consciousness, Orthostatic Hypotension
This report suggests a potential Karvezide Loss Of Consciousness side effect(s) that can have serious consequences. A 51-year-old male patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: hypertension and used Karvezide (dosage: Strength: 300mg/25mg) starting
Nov 09, 2012. After starting Karvezide the patient began experiencing various side effects, including: Loss Of Consciousness, Orthostatic HypotensionAdditional drugs used concurrently: NA.The patient was hospitalized. Although Karvezide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Loss Of Consciousness, may still occur.
Karvezide Side Effect Report#9775654
Fall, Syncope, Vertigo
This Fall problem was reported by a physician from IT. A 80-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: essential hypertension. On
Nov 10, 2013 this consumer started treatment with Karvezide (dosage: NA). The following drugs were being taken at the same time:
  • Cardura (Strength:2 Mg)
When using Karvezide, the patient experienced the following unwanted symptoms/side effects: Fall, Syncope, VertigoThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Fall, may become evident only after a product is in use by the general population.
Karvezide Side Effect Report#9648540
Cerebrovascular Accident, Feeling Abnormal, Cerebrovascular Accident
This Cerebrovascular Accident side effect was reported by a health professional from AU. A 78-year-old female patient (weight:NA) experienced the following symptoms/conditions: rheumatoid arthritis.The patient was prescribed Karvezide (drug dosage: Strength :300/12.5), which was initiated on
Dec 21, 2009. Concurrently used drugs:
  • Actemra (Form: Infusion?frequency: Every 4 Weeks)
  • Methotrexate
  • Pariet
.After starting to take Karvezide the consumer reported adverse symptoms, such as: Cerebrovascular Accident, Feeling Abnormal, Cerebrovascular AccidentThese side effects may potentially be related to Karvezide. The patient was hospitalized and became disabled.
Karvezide Side Effect Report#9648503
Gynaecomastia, Breast Pain
This is a report of a 77-year-old male patient (weight: NA) from AU, suffering from the following health symptoms/conditions: hypertension, who was treated with Karvezide (dosage: Daily Dose: 300/25, start time:
Nov 10, 2010), combined with:
  • Sotalol (Daily Dose: 80)
  • Coversyl (Daily Dose: 5)
  • Fish Oil
  • Multivitamins
and developed a serious reaction and side effect(s): Gynaecomastia, Breast Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Karvezide treatment in male patients, resulting in Gynaecomastia side effect.
Karvezide Side Effect Report#9492821
Presyncope, Nausea, Cold Sweat, Hypotension
This report suggests a potential Karvezide Presyncope side effect(s) that can have serious consequences. A 84-year-old male patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: hypertension,atrial fibrillation and used Karvezide (dosage: NA) starting
Jan 01, 2013. After starting Karvezide the patient began experiencing various side effects, including: Presyncope, Nausea, Cold Sweat, HypotensionAdditional drugs used concurrently:
  • Coumadin (Strength: 5 Mg)
  • Lopressor (Sterngth: 100 Mg)
  • Xatral (Strength: 10 Mg)
Although Karvezide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Presyncope, may still occur.
Karvezide Side Effect Report#9305403
Hyponatraemia, Vomiting, Gastroenteritis Viral, Laboratory Test Abnormal, Muscle Rigidity, Somnolence, Activities Of Daily Living Impaired
This Hyponatraemia problem was reported by a consumer or non-health professional from ES. A 83-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension. On 201006 this consumer started treatment with Karvezide Film-coated Tabs 300/12.5 Mg (dosage: 1 Df=300 Mg/12,5 Mg Tablet?last Dose On 16mar2013.). The following drugs were being taken at the same time:
  • Somnovit
  • Adolonta (Adolonta Retard)
  • Simvastatin
  • Flatoril
  • Omeprazole
  • Ebixa
When using Karvezide Film-coated Tabs 300/12.5 Mg, the patient experienced the following unwanted symptoms/side effects: Hyponatraemia, Vomiting, Gastroenteritis Viral, Laboratory Test Abnormal, Muscle Rigidity, Somnolence, Activities Of Daily Living ImpairedThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hyponatraemia, may become evident only after a product is in use by the general population.
Karvezide Side Effect Report#9263133
Pulmonary Oedema, Local Swelling, Spider Vein, Cough
This Pulmonary Oedema side effect was reported by a consumer or non-health professional from AU. A 69-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Karvezide (drug dosage: Karvezide 300/12.5), which was initiated on 201302. Concurrently used drugs: NA..After starting to take Karvezide the consumer reported adverse symptoms, such as: Pulmonary Oedema, Local Swelling, Spider Vein, CoughThese side effects may potentially be related to Karvezide.
Karvezide Side Effect Report#9234741
Renal Failure Acute, Haemoglobin Decreased
This is a report of a 85-year-old female patient (weight: NA) from ES, suffering from the following health symptoms/conditions: hypertension,pain,arthropathy, who was treated with Karvezide (dosage: Df: 300/12.5 Mg, start time: 200609), combined with:
  • Ibuprofen (Last Dose: 15jun2010)
  • Lornoxicam (Last Dose: 26may2010)
  • Arcoxia (Last Dose: 26may2010)
  • Estomil (Last Dose: 15jun2010)
  • Serc (Last Dose: 15jun2010)
and developed a serious reaction and side effect(s): Renal Failure Acute, Haemoglobin Decreased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Karvezide treatment in female patients, resulting in Renal Failure Acute side effect. The patient was hospitalized.
Karvezide Side Effect Report#9204805
Vertigo, Photophobia, Dizziness, Hypokalaemia
This report suggests a potential Karvezide Vertigo side effect(s) that can have serious consequences. A 66-year-old female patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: NA and used Karvezide (dosage: Interr 9mar13) starting
Jan 01, 2013. After starting Karvezide the patient began experiencing various side effects, including: Vertigo, Photophobia, Dizziness, HypokalaemiaAdditional drugs used concurrently:
  • Eutirox (Tabs)
  • Limpidex (Caps)
  • Eutirox (Tabs)
  • Dibase (1df= 25.000 Iu/2.5 Ml)
The patient was hospitalized. Although Karvezide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Vertigo, may still occur.
Karvezide Side Effect Report#8910129
Atrioventricular Block Complete, Hyperkalaemia, Ventricular Extrasystoles
This Atrioventricular Block Complete problem was reported by a consumer or non-health professional from ES. A 69-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension,hepatic cirrhosis,respiratory disorder,type 2 diabetes mellitus,cardiac failure,dyslipidaemia. On 2003 this consumer started treatment with Karvezide (dosage: NA). The following drugs were being taken at the same time:
  • Aldactone
  • Onbrez
  • Metformin
  • Furosemide
  • Simvastatin
When using Karvezide, the patient experienced the following unwanted symptoms/side effects: Atrioventricular Block Complete, Hyperkalaemia, Ventricular ExtrasystolesThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Atrioventricular Block Complete, may become evident only after a product is in use by the general population.
Karvezide Side Effect Report#8778836
Acute Left Ventricular Failure, Diastolic Dysfunction, Cardiac Murmur, Rales, Pulmonary Oedema, Dyspnoea, Pleural Effusion, Chest Discomfort, Cardiac Disorder
This Acute Left Ventricular Failure side effect was reported by a physician from AU. A 70-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Karvezide (drug dosage: 1 Df, Daily), which was initiated on
Jul 25, 2012. Concurrently used drugs:
  • Lipitor (40 Mg, Daily)
  • Metformin (500 Mg, Daily)
  • Nexium (20 Mg, Daily)
  • Analgesics
  • Gilenya (0.5 Mg, Qd)
.After starting to take Karvezide the consumer reported adverse symptoms, such as: Acute Left Ventricular Failure, Diastolic Dysfunction, Cardiac Murmur, Rales, Pulmonary Oedema, Dyspnoea, Pleural Effusion, Chest Discomfort, Cardiac DisorderThese side effects may potentially be related to Karvezide. The patient was hospitalized.
Karvezide Side Effect Report#8769066
Hypokalaemia, Blood Lactic Acid Increased
This is a report of a 70-year-old male patient (weight: NA) from IT, suffering from the following health symptoms/conditions: hypertension,type 2 diabetes mellitus, who was treated with Karvezide Tabs (dosage: 1df=1 Dosage Unit, start time:
Feb 17, 2012), combined with:
  • Glucophage Tabs 500 Mg (1df=2 Dosage Units)
and developed a serious reaction and side effect(s): Hypokalaemia, Blood Lactic Acid Increased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Karvezide Tabs treatment in male patients, resulting in Hypokalaemia side effect. The patient was hospitalized.
Karvezide Side Effect Report#8308894-4
Lactic Acidosis, Renal Failure Acute, Gastroenteritis
This report suggests a potential Karvezide Tabs 300mg/12.5mg Lactic Acidosis side effect(s) that can have serious consequences. A 84-year-old female patient (weight: NA) from Italy was diagnosed with the following symptoms/conditions: hypertension,diabetes mellitus and used Karvezide Tabs 300mg/12.5mg (dosage: NA) starting
Apr 06, 2012. After starting Karvezide Tabs 300mg/12.5mg the patient began experiencing various side effects, including: Lactic Acidosis, Renal Failure Acute, GastroenteritisAdditional drugs used concurrently:
  • Repaglinide ((5mg+500mg Tab) 3 Dosage Units/die)
  • Metformin Hcl (Metformina Teva)
  • Claritromicina (500mg Film Covered Tab Claritromicina Teva)
Although Karvezide Tabs 300mg/12.5mg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Lactic Acidosis, may still occur.
Karvezide Side Effect Report#7948431-7
Bladder Cancer
This Bladder Cancer problem was reported by a consumer or non-health professional from Germany. A 65-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Karvezide (hydrochlorothiazide, Irbesartan) (dosage: NA). The following drugs were being taken at the same time:
  • Rasilez (aliskiren)
  • Doxazosine (doxazosin Mesilate)
  • Glurenorm (gliquidone)
  • Aspirin
  • Atorvastatin
  • Actos ((1-0-0) Per Oral)
When using Karvezide (hydrochlorothiazide, Irbesartan), the patient experienced the following unwanted symptoms/side effects: Bladder CancerThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Bladder Cancer, may become evident only after a product is in use by the general population.
Karvezide Side Effect Report#7758534-8
Anuria, Dysuria, Pain, Renal Pain, Palpitations, Urinary Tract Infection, Insomnia, Pyelonephritis, Flank Pain
This Anuria side effect was reported by a physician from Australia. A 61-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Karvezide (karvezide -hydrochlorothiazide Irbesartan) 150 Mg (not Spec (drug dosage: (150 Mg Qd), (df)), which was initiated on
Jun 09, 2011. Concurrently used drugs: NA..After starting to take Karvezide (karvezide -hydrochlorothiazide Irbesartan) 150 Mg (not Spec the consumer reported adverse symptoms, such as: Anuria, Dysuria, Pain, Renal Pain, Palpitations, Urinary Tract Infection, Insomnia, Pyelonephritis, Flank PainThese side effects may potentially be related to Karvezide (karvezide -hydrochlorothiazide Irbesartan) 150 Mg (not Spec. The patient was hospitalized.
Karvezide Side Effect Report#7386586-6
Meningitis Bacterial
This is a report of a male patient (weight: NA) from Spain, suffering from the following health symptoms/conditions: NA, who was treated with Karvezide (dosage: Hydrochlorthiazide 12.5 Mg Irbesartan 300 Mg, start time:
Feb 09, 2011), combined with:
  • Bevacizumab
  • Irinotecan Hcl
  • Amlodipino
  • Capecitabine (Frequency : 12 Hours X 14 Days)
and developed a serious reaction and side effect(s): Meningitis Bacterial after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Karvezide treatment in male patients, resulting in Meningitis Bacterial side effect. The patient was hospitalized.
Karvezide Side Effect Report#7222284-7
Cold Type Haemolytic Anaemia
This report suggests a potential Karvezide Tabs 150mg/12.5mg Cold Type Haemolytic Anaemia side effect(s) that can have serious consequences. A 60-year-old male patient (weight: NA) from Italy was diagnosed with the following symptoms/conditions: hypertension and used Karvezide Tabs 150mg/12.5mg (dosage: 1 Df= 15omg+12 Mg Oral Tabs, At The Dosage Of 1 Posologic Unit/day,) starting
Feb 20, 2000. After starting Karvezide Tabs 150mg/12.5mg the patient began experiencing various side effects, including: Cold Type Haemolytic AnaemiaAdditional drugs used concurrently: NA.The patient was hospitalized. Although Karvezide Tabs 150mg/12.5mg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cold Type Haemolytic Anaemia, may still occur.
Karvezide Side Effect Report#7222214-8
Vomiting, Hyperglycaemia, Hypercreatinaemia, Tonic Clonic Movements, Azotaemia, Electrocardiogram Qt Prolonged, Constipation, Hypernatraemia
This Vomiting problem was reported by a health professional from Denmark. A 76-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Nov 11, 2010 this consumer started treatment with Karvezide (irbesartan Hydrochlorothiazide) (tablets) (irbesartan Hy (dosage: NA). The following drugs were being taken at the same time:
  • Karvezide (irbesartan)
  • Thymanax (agomelatine) (25 Milligram, Tablets)
  • Lansoprazole
  • Escitalopram (5 Mg (5 Mg, 1 In 1 D), Oral)
When using Karvezide (irbesartan Hydrochlorothiazide) (tablets) (irbesartan Hy, the patient experienced the following unwanted symptoms/side effects: Vomiting, Hyperglycaemia, Hypercreatinaemia, Tonic Clonic Movements, Azotaemia, Electrocardiogram Qt Prolonged, Constipation, HypernatraemiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Vomiting, may become evident only after a product is in use by the general population.
Karvezide Side Effect Report#7098185-4
Cold Type Haemolytic Anaemia
This Cold Type Haemolytic Anaemia side effect was reported by a physician from Italy. A 60-year-old male patient (weight:NA) experienced the following symptoms/conditions: hypertension.The patient was prescribed Karvezide Tabs 150mg/12.5mg (drug dosage: 1 Df= 15omg+12 Mg Oral Tabs, At The Dosage Of 1 Posologic Unit/day,), which was initiated on
Feb 20, 2000. Concurrently used drugs: NA..After starting to take Karvezide Tabs 150mg/12.5mg the consumer reported adverse symptoms, such as: Cold Type Haemolytic AnaemiaThese side effects may potentially be related to Karvezide Tabs 150mg/12.5mg. The patient was hospitalized.
Karvezide Side Effect Report#7092312-0
Anaemia, Cryoglobulinaemia, Haemoglobin Decreased, Red Blood Cell Count Decreased, White Blood Cell Count Decreased
This is a report of a 60-year-old male patient (weight: NA) from Italy, suffering from the following health symptoms/conditions: hypertension, who was treated with Karvezide Tabs 150mg/12.5mg (dosage: 1 Df= 15omg+12 Mg Oral Tabs, At The Dosage Of 1 Posologic Unit/day, start time:
Feb 20, 2000), combined with: NA. and developed a serious reaction and side effect(s): Anaemia, Cryoglobulinaemia, Haemoglobin Decreased, Red Blood Cell Count Decreased, White Blood Cell Count Decreased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Karvezide Tabs 150mg/12.5mg treatment in male patients, resulting in Anaemia side effect. The patient was hospitalized.
Karvezide Side Effect Report#7067585-0
Anaemia
This report suggests a potential Karvezide Anaemia side effect(s) that can have serious consequences. A 60-year-old male patient (weight: NA) from Italy was diagnosed with the following symptoms/conditions: hypertension and used Karvezide (dosage: NA) starting
Feb 28, 2000. After starting Karvezide the patient began experiencing various side effects, including: AnaemiaAdditional drugs used concurrently: NA.The patient was hospitalized. Although Karvezide demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anaemia, may still occur.
Karvezide Side Effect Report#7024208-4
Renal Impairment
This Renal Impairment problem was reported by a physician from Australia. A 64-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: hypertension. On NS this consumer started treatment with Karvezide Tabs 300mg/12.5mg (dosage: 1 Df= 12.5mg). The following drugs were being taken at the same time:
  • Minipress (Tabs)
  • Hydralazine Hcl
  • Norvasc
  • Aldactone
  • Verapamil
When using Karvezide Tabs 300mg/12.5mg, the patient experienced the following unwanted symptoms/side effects: Renal ImpairmentAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Renal Impairment, may become evident only after a product is in use by the general population.
Karvezide Side Effect Report#6922767-0
Disorientation, Hyponatraemia, Nausea, Vomiting
This Disorientation side effect was reported by a physician from Italy. A 75-year-old female patient (weight:NA) experienced the following symptoms/conditions: hypertension.The patient was prescribed Karvezide Tabs 150mg/12.5mg (drug dosage: 1 Df = Karvezide Tablets 150/12.5mg), which was initiated on
Jul 12, 2005. Concurrently used drugs:
  • Lasix (1 Df = Lasix 25 Mg Tabs)
  • Lanoxin (1 Df = Lanoxin Tabs 0.125mg)
  • Lopressor
  • Travatan (1 Df = 40 Mcg/ml Collyrium)
  • Sintrom (1 Mg Tabs)
  • Deltacortene (5 Mg Tabs)
  • Chloroquine Phosphate (1df = 250mg Tabs)
.After starting to take Karvezide Tabs 150mg/12.5mg the consumer reported adverse symptoms, such as: Disorientation, Hyponatraemia, Nausea, VomitingThese side effects may potentially be related to Karvezide Tabs 150mg/12.5mg. The patient was hospitalized.
Karvezide Side Effect Report#6870949-9
Disorientation, Hyponatraemia, Nausea, Vomiting
This is a report of a 75-year-old female patient (weight: NA) from Italy, suffering from the following health symptoms/conditions: hypertension, who was treated with Karvezide Tabs 150mg/12.5mg (dosage: 1 Df = Karvezide Tablets 150/12.5mg, start time:
Jul 12, 2005), combined with:
  • Lasix (1 Df = Lasix 25 Mg Tabs)
  • Lanoxin (1 Df = Lanoxin Tabs 0.125mg)
  • Lopressor
  • Travatan (1 Df = 40 Mcg/ml Collyrium)
  • Sintrom (1 Mg Tabs)
  • Deltacortene (5 Mg Tabs)
  • Chloroquine Phosphate (1df = 250mg Tabs)
and developed a serious reaction and side effect(s): Disorientation, Hyponatraemia, Nausea, Vomiting after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Karvezide Tabs 150mg/12.5mg treatment in female patients, resulting in Disorientation side effect. The patient was hospitalized.


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The appearance of Karvezide on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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What are common Karvezide Side Effects for Women?

Women Side EffectsReports
Hyponatraemia 8
Fall 5
Vomiting 4
Hypokalaemia 3
Renal Failure Acute 3
Staphylococcal Infection 3
Suicidal Ideation 3
Upper Limb Fracture 3
Ageusia 2
Bradycardia 2

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    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Karvezide reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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