Keppra Safety Questions, Keppra Answers
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Keppra Safety Reports
Total Keppra reports: 688.Keppra FDA safety alerts: 2003 2008 .
Reported deaths: 84 Reported hospitalizations: 287.
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Reported Keppra Side Effects: thrombocytopenia, condition aggravated, grand mal convulsion, fatigue, pregnancy with contraceptive device, depression, premature baby, pregnancy, abortion spontaneous, aggression, caesarean section.
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Keppra Side Effects Report #5253871-3Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Feb 12, 2007. Male patient was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: apgar score low, caesarean section, cystitis, enterobacter infection, hydronephrosis, klebsiella infection, oral intake reduced, phimosis. KEPPRA dosage: 2000 MG TRP. During the same period patient was treated with TEGRETOL, CLONAZEPAM. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5254738-7
KEPPRA problem was reported by a Pharmacist from UNITED STATES on Feb 12, 2007. Female patient, 33 years of age, weighting 104.7 lb, was diagnosed with convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, headache, hypersensitivity, leukopenia, lip disorder, lymphopenia. KEPPRA dosage: unknown. During the same period patient was treated with LAMICTAL, IMITREX, LEXAPRO, RELAFEN. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5255117-9
Physician from GERMANY reported KEPPRA problem on Feb 13, 2007. Female patient, 39 years of age, weighting 127.9 lb, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: agitation, convulsion, delusional disorder, persecutory type, irritability, psychotic disorder, weight decreased. KEPPRA dosage: 250 MG 2/D PO. During the same period patient was treated with NEURONTIN, CARBAMAZEPINE. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5255120-9
KEPPRA problem was reported by a Consumer or non-health professional from GERMANY on Feb 13, 2007. Female patient, 39 years of age, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: autoimmune hepatitis, cardiac arrest, hepatocellular damage, hepatotoxicity, hyponatraemia, polyuria, sinus arrest, supraventricular extrasystoles. KEPPRA dosage: 500 MG /D PO. During the same period patient was treated with PHENYTOIN, VALPROATE. Patient recovered.
Keppra Side Effects Report #5255809-1
Physician from GERMANY reported KEPPRA problem on Feb 14, 2007. Female patient, 66 years of age, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: photosensitivity reaction, rash. KEPPRA dosage: 500 MG 3/D. During the same period patient was treated with UNACID, TRILEPTAL, RAMIPRIL, AMLODIPINE, PANTOZOL, BELOC, BEKAWAN, BERODUAL. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5255819-4
KEPPRA problem was reported by a Consumer or non-health professional from FRANCE on Feb 14, 2007. Male patient, 52 years of age, was diagnosed with status epilepticus and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: condition aggravated, convulsion, status epilepticus. KEPPRA dosage: unknown. During the same period patient was treated with PENTOTHAL, DEPAKENE, RIVOTRIL, FOSPHENYTOIN. Patient died on 01/24/2007.
Keppra Side Effects Report #5255879-0
Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Feb 14, 2007. Male patient, 40 years of age, weighting 149.9 lb, was diagnosed with convulsion prophylaxis, meningitis bacterial and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: anaemia, gastric ulcer, haemodialysis, influenza, nausea, pharyngeal oedema, renal failure, stevens-johnson syndrome, stress ulcer. KEPPRA dosage: 1000 MG 2/D PO. During the same period patient was treated with TROVAFLOXINE, CEFEPIME. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5256274-0
KEPPRA problem was reported by a Physician from UNITED STATES on Feb 15, 2007. Male patient was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: premature baby. KEPPRA dosage: 3500 MG/D TRP. During the same period patient was treated with TRILEPTAL, PRENATAL VITAMINS. Patient recovered.
Keppra Side Effects Report #5257299-1
Physician from UNITED STATES reported KEPPRA problem on Feb 15, 2007. Female patient, 32 years of age, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: hellp syndrome, pre-eclampsia, premature labour. KEPPRA dosage: 3500 MG /D PO. During the same period patient was treated with TRILEPTAL. Patient recovered.
Keppra Side Effects Report #5257302-9
KEPPRA problem was reported by a Health Professional from UNITED STATES on Feb 15, 2007. Male patient, weighting 5.60 lb, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: dacryostenosis congenital. KEPPRA dosage: 3000 MG /D TRP. During the same period patient was treated with AMBIEN, KENALOG, PRENATAL VITAMINS, PHENERGAN, ALBUTEROL, METOCLOPRAMIDE, PROZAC, FERROUS SULPHATE. Patient recovered.
Keppra Side Effects Report #5257797-0
Consumer or non-health professional from GERMANY reported KEPPRA problem on Feb 15, 2007. Female patient was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: unintended pregnancy. KEPPRA dosage: 500 MG 2/D. Patient recovered.
Keppra Side Effects Report #5258816-8
KEPPRA problem was reported by a Physician from UNITED STATES on Mar 06, 2007. Male patient was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: atrial septal defect, heart disease congenital, patent ductus arteriosus, urinary tract malformation, ventricular hypertrophy. KEPPRA dosage: 1000 MG BID PO. Patient recovered.
Keppra Side Effects Report #5259481-6
Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Feb 16, 2007. Female patient, 52 years of age, was diagnosed with epilepsy, urinary tract infection and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: body temperature increased, convulsion, dehydration, fall, feeding tube complication, hypersensitivity, hypotension, incorrect dose administered. KEPPRA dosage: 1500 MG 2/D PO. During the same period patient was treated with LEVAQUIN, DILANTIN. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5259496-8
KEPPRA problem was reported by a Physician from UNITED STATES on Feb 16, 2007. Female patient, 23 years of age, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis. KEPPRA dosage: 1000 MG /D. During the same period patient was treated with FOLIC ACID, PHENYTOIN. Patient recovered.
Keppra Side Effects Report #5261504-5
Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Feb 20, 2007. Female patient, 63 years of age, was diagnosed with convulsion, dementia alzheimer's type and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: agitation, convulsion, dementia alzheimer's type, disease progression, lethargy, nausea, somnolence, urinary tract infection. KEPPRA dosage: unknown. During the same period patient was treated with NAMENDA, ARICEPT, DILANTIN. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5262314-5
KEPPRA problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 08, 2007. Male patient, 59 years of age, weighting 184.0 lb, was diagnosed with pain and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, aggression. KEPPRA dosage: unknown. During the same period patient was treated with ENALAPRIL MALEATE, METOPROLOL SUCCINATE, FELODIPINE. Patient recovered.
Keppra Side Effects Report #5268108-9
Health Professional from UNITED STATES reported KEPPRA problem on Mar 13, 2007. Female patient, 14 years of age, weighting 185.0 lb, was diagnosed with convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: completed suicide. KEPPRA dosage: 250 MG, BID. During the same period patient was treated with TRILEPTAL. Patient died on 01/19/2007.
Keppra Side Effects Report #5269572-1
KEPPRA problem was reported by a Consumer or non-health professional from GERMANY on Feb 26, 2007. Female patient was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: convulsion, fatigue. KEPPRA dosage: unknown. During the same period patient was treated with VALPROATE, MONOMACK, NEXIUM, METOPROLOL SUCCINATE, THIAMINE, VITAMIN B6. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5269573-3
Consumer or non-health professional from FRANCE reported KEPPRA problem on Feb 26, 2007. Female patient, 76 years of age, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: haemoglobin decreased, platelet count decreased, white blood cell count decreased. KEPPRA dosage: 1000 MG 1/D PO. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5269589-7
KEPPRA problem was reported by a Physician from GERMANY on Feb 26, 2007. Female patient, 24 years of age, was diagnosed with grand mal convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: anorexia, fatigue, irritability, unintended pregnancy. KEPPRA dosage: 1250 MG/D. Patient recovered.
Keppra Side Effects Report #5271559-X
Physician from UNITED STATES reported KEPPRA problem on Mar 02, 2007. Female patient, 36 years of age, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: pancytopenia. KEPPRA dosage: unknown. During the same period patient was treated with DEPAKOTE. Patient recovered.
Keppra Side Effects Report #5271880-5
KEPPRA problem was reported by a Consumer or non-health professional from SWITZERLAND on Mar 01, 2007. Male patient, 42 years of age, weighting 132.3 lb, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: hallucination, paranoia, treatment noncompliance. KEPPRA dosage: 500 MG 2/D; PO. During the same period patient was treated with TEMESTA, PRAZINE, SUBUTEX, DORMICUM, ROHYPNOL, LISITRIL, METOPROLOL SUCCINATE. Patient recovered.
Keppra Side Effects Report #5272464-5
Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Mar 02, 2007. Female patient, 52 years of age, was diagnosed with epilepsy, urinary tract infection and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: convulsion, dehydration, fall, hypersensitivity, hypotension, infection, rash, traumatic brain injury. KEPPRA dosage: 1500 MG 2/D PO. During the same period patient was treated with LEVAQUIN, DILANTIN. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5272576-6
KEPPRA problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 02, 2007. Female patient, 52 years of age, was diagnosed with epilepsy, urinary tract infection and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: convulsion, dehydration, fall, hypersensitivity, hypotension, traumatic brain injury, underdose, urinary tract infection. KEPPRA dosage: 1500 MG 2/D PO. During the same period patient was treated with LEVAQUIN, DILANTIN. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5276858-3
Physician from UNITED STATES reported KEPPRA problem on Mar 05, 2007. Male patient, weighting 16.73 lb, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: ventricular septal defect. KEPPRA dosage: 1500 MG TRP. During the same period patient was treated with FOLIC ACID, PRENATAL VITAMINS. Patient recovered.
Keppra Side Effects Report #5278009-8
KEPPRA problem was reported by a Consumer or non-health professional from ITALY on Mar 05, 2007. Female patient, 59 years of age, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: bone marrow failure. KEPPRA dosage: 500 MG /D PO. During the same period patient was treated with TEGRETOL. Patient recovered.
Keppra Side Effects Report #5278010-4
Consumer or non-health professional from GERMANY reported KEPPRA problem on Mar 05, 2007. Female patient, 38 years of age, was diagnosed with epilepsy, spondyloarthropathy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: aplastic anaemia, bone marrow failure, convulsion, leukopenia. KEPPRA dosage: unknown. During the same period patient was treated with CARBAMAZEPINE, AZULFIDINE, NAPROXEN. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5278011-6
KEPPRA problem was reported by a Physician from TURKEY on Mar 05, 2007. Male patient, 31 years of age, weighting 103.6 lb, was diagnosed with dysphemia, epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, anger, anxiety, self injurious behaviour. KEPPRA dosage: 250 MG 2/D PO. During the same period patient was treated with FRISIUM. Patient recovered.
Keppra Side Effects Report #5278012-8
Consumer or non-health professional from UNITED KINGDOM reported KEPPRA problem on Mar 05, 2007. Male patient, 35 years of age, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: condition aggravated, epilepsy. KEPPRA dosage: 250 MG 3/D. During the same period patient was treated with LAMOTRIGINE, CARBAMAZEPINE. Patient recovered.
Keppra Side Effects Report #5278401-1
KEPPRA problem was reported by a Consumer or non-health professional from FRANCE on Mar 08, 2007. Female patient, 74 years of age, weighting 123.5 lb, was diagnosed with epilepsy, pain and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: anorexia, asthenia, delirium, hallucination, loss of consciousness, pulmonary embolism, somnolence. KEPPRA dosage: 500 MG 2/D PO. During the same period patient was treated with NEURONTIN, ARIMIDEX, EZETROL, METOPROLOL TARTRATE, KARDEGIC, INIPOMP. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5278823-9
Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Mar 06, 2007. Female patient, 73 years of age, was diagnosed with convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: condition aggravated, convulsion, coronary artery disease, dementia, dyskinesia, encephalopathy, hallucination, visual. KEPPRA dosage: unknown. During the same period patient was treated with A BLOOD PRESSURE MED. Patient was hospitalized. Patient died on 11/14/2006.
Keppra Side Effects Report #5279246-9
KEPPRA problem was reported by a Consumer or non-health professional from ITALY on Mar 06, 2007. Female patient, 63 years of age, was diagnosed with partial seizures and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: hepatitis acute, hepatorenal failure. KEPPRA dosage: 500 MG /D PO. During the same period patient was treated with DESAMETASONE, WARFARIN, OMEPRAZOLE, OFFICINAL PLANT, HOMEOPATIC PREPARATIONS, FOOD SUPPLEMENTS. Patient was hospitalized. Patient died on 07/28/2006.
Keppra Side Effects Report #5279690-X
Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Mar 07, 2007. Female patient was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: trisomy 18. KEPPRA dosage: 1750 MG TRP. Patient died on 02/21/2007.
Keppra Side Effects Report #5279691-1
KEPPRA problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 07, 2007. Female patient, 37 years of age, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: biopsy chorionic villous abnormal, foetal disorder, trisomy 18, twin pregnancy. KEPPRA dosage: 1750 MG/D PO. During the same period patient was treated with PHENOBARBITAL, PRENATAL VITAMINS, FOLIC ACID. Patient recovered.
Keppra Side Effects Report #5281065-4
Consumer or non-health professional from NETHERLANDS reported KEPPRA problem on Mar 07, 2007. Male patient, 81 years of age, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: dehydration, liver disorder, renal disorder. KEPPRA dosage: 250 MG 2/D. During the same period patient was treated with TILDIEM, FUROSEMIDE, THYRAX, CARDIO PCH, CARBAMAZEPINUM RETARD, DIPHANTOINE. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5281218-5
KEPPRA problem was reported by a Consumer or non-health professional from NETHERLANDS on Mar 07, 2007. Male patient, 81 years of age, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: dehydration, liver disorder, renal disorder. KEPPRA dosage: 250 MG 2/D. During the same period patient was treated with TILDIEM, FUROSEMIDE GF, THYRAX, CARDIO PCH, CARBAMAZEPINUM RETARD, DIPHANTOINE Z. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5281255-0
Consumer or non-health professional from GERMANY reported KEPPRA problem on Mar 09, 2007. Female patient, 51 years of age, weighting 116.8 lb, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: agranulocytosis, condition aggravated, lymphocyte percentage decreased, red blood cell count decreased, white blood cell count decreased. KEPPRA dosage: 500 MG 4/D PO. During the same period patient was treated with DOXYCYCLIN, LEVOTHYROXINE, NEXIUM, KALINOR. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5281673-0
KEPPRA problem was reported by a Consumer or non-health professional from FRANCE on Mar 08, 2007. Male patient, 68 years of age, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: haematuria, heparin-induced thrombocytopenia, hypothermia, pancytopenia. KEPPRA dosage: 1500 MG /D PO. During the same period patient was treated with AXEPIM, BIONOLYTE, DEROXAT, OMEPRAZOLE, TEMODAL, LOVENOX. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5281891-1
Consumer or non-health professional from FRANCE reported KEPPRA problem on Mar 08, 2007. Female patient, 72 years of age, weighting 161.6 lb, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: joint sprain, pancytopenia. KEPPRA dosage: 500 MG 2/D PO. During the same period patient was treated with DEPAKENE, TEMESTA, BI PREDONIUM, ZYRTEC, SEROPRAM. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5282609-9
KEPPRA problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 08, 2007. Female patient, 26 years of age, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: abortion spontaneous. KEPPRA dosage: 200 MG/D. Patient recovered.
Keppra Side Effects Report #5283351-0
Pharmacist from UNITED STATES reported KEPPRA problem on Mar 28, 2007. Female patient, 45 years of age, weighting 126.0 lb, was diagnosed with convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: neutrophil count decreased, white blood cell count decreased. KEPPRA dosage: unknown. Patient recovered.
Keppra Side Effects Report #5284047-1
KEPPRA problem was reported by a Health Professional from GERMANY on Mar 13, 2007. Female patient was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: rash, status epilepticus. KEPPRA dosage: 500 MG 2/D. During the same period patient was treated with LAMOTRIGINE, LYRICA. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5284053-7
Physician from GERMANY reported KEPPRA problem on Mar 12, 2007. Female patient was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, grand mal convulsion, hallucination, visual, visual disturbance. KEPPRA dosage: 2500 MG /D PO. During the same period patient was treated with ERGENYL CHRONO, VALPROATE CHRONO, TOPIRAMATE, DOCITON, ENALAPRIL MALEATE, HUMINSULIN NORMAL. Patient recovered.
Keppra Side Effects Report #5284054-9
KEPPRA problem was reported by a Physician from GERMANY on Mar 12, 2007. Female patient, 80 years of age, weighting 165.3 lb, was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, weight increased. KEPPRA dosage: 250 MG /D PO. During the same period patient was treated with CARBAMAZEPINE, ASPIRIN. Patient died on 09/09/2006.
Keppra Side Effects Report #5286215-1
Consumer or non-health professional from UNITED STATES reported KEPPRA problem on Mar 14, 2007. Female patient, 75 years of age, was diagnosed with convulsion, neoplasm malignant and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: balance disorder, convulsion, fatigue, platelet count decreased, somnolence. KEPPRA dosage: 750 MG 2/D PO. During the same period patient was treated with TEMODAR, STEROIDS. Patient recovered.
Keppra Side Effects Report #5287281-X
KEPPRA problem was reported by a Physician from GERMANY on Mar 14, 2007. Male patient, 17 years of age, was diagnosed with complex partial seizures, grand mal convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: aggression. KEPPRA dosage: 1500 MG 2/D PO. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5287283-3
Consumer or non-health professional from GERMANY reported KEPPRA problem on Mar 13, 2007. Male patient was diagnosed with epilepsy and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: jealous delusion. KEPPRA dosage: 500 MG 2/D. Patient was hospitalized. Patient recovered.
Keppra Side Effects Report #5228832-0
KEPPRA problem was reported by a Physician from UNITED STATES on Jan 18, 2007. Female patient, weighting 17.86 lb, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: acrochordon. KEPPRA dosage: unknown. During the same period patient was treated with VITAMINS, RHOGAM. Patient recovered.
Keppra Side Effects Report #5242115-4
Physician from UNITED STATES reported KEPPRA problem on Jan 26, 2007. Female patient, weighting 17.86 lb, was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: acrochordon. KEPPRA dosage: unknown. During the same period patient was treated with VITAMINS NOS, RHOGAM. Patient recovered.
Keppra Side Effects Report #5287915-X
KEPPRA problem was reported by a Physician from UNITED STATES on Apr 03, 2007. Female patient, child 4 years of age, weighting 39.68 lb, was diagnosed with convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, agitation, hostility, psychotic disorder. KEPPRA dosage: 200MG BID PO. Patient recovered.
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Drug Information: Levetiracetam
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a699059.html
(lee ve tye ra' se tam)IMPORTANT WARNING:
| [Posted 01/31/2008] FDA informed healthcare professionals that the Agency has analyzed reports of suicidality (suicidal behavior or ideation) from placebo-controlled clinical studies of eleven drugs used to treat epilepsy as well as psychiatric disorders, and other conditions. In the FDA's analysis, patients receiving antiepileptic drugs had approximately twice the risk of suicidal behavior or ideation (0.43%) compared to patients receiving placebo (0.22%). The increased risk of suicidal behavior and suicidal ideation was observed as early as one week after starting the antiepileptic drug and continued through 24 weeks. The results were generally consistent among the eleven drugs. The relative risk for suicidality was higher in patients with epilepsy compared to patients who were given one of the drugs in the class for psychiatric or other conditions.Healthcare professionals should closely monitor all patients currently taking or starting any antiepileptic drug for notable changes in behavior that could indicate the emergence or worsening of suicidal thoughts or behavior or depression.The drugs included in the analyses include (some of these drugs are also available in generic form): Carbamazepine (marketed as Carbatrol, Equetro, Tegretol, Tegretol XR)Felbamate (marketed as Felbatol)Gabapentin (marketed as Neurontin) Lamotrigine (marketed as Lamictal) Levetiracetam (marketed as Keppra) Oxcarbazepine (marketed as Trileptal)Pregabalin (marketed as Lyrica) Tiagabine (marketed as Gabitril)Topiramate (marketed as Topamax) Valproate (marketed as Depakote, Depakote ER, Depakene, Depacon) Zonisamide (marketed as Zonegran) Although the 11 drugs listed above were the ones included in the analysis, FDA expects that the increased risk of suicidality is shared by all antiepileptic drugs and anticipates that the class labeling changes will be applied broadly. For more information visit the FDA website at: http://www.fda.gov/medwatch/safety/2008/safety08.htm#Antiepileptic and http://www.fda.gov/cder/drug/InfoSheets/HCP/antiepilepticsHCP.htm. |
Why is this medication prescribed?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Levetiracetam is used in combination with other medications to treat certain types of seizures in people with epilepsy. Levetiracetam is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.
How should this medicine be used?
Levetiracetam comes as a solution (liquid) and a tablet to take by mouth. It is usually taken twice a day, once in the morning and once at night, with or without food. Try to take levetiracetam at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take levetiracetam exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the tablets whole; do not split, chew, or crush them.
If you are taking the oral solution, do not use a household spoon to measure your dose. You might not get the right amount of medication. Ask your doctor or pharmacist to recommend a medicine dropper, spoon, cup, or syringe and to show you how to use it to measure your medication.
Your doctor may start you on a low dose of levetiracetam and gradually increase your dose, not more often than once every 2 weeks.
Levetiracetam controls epilepsy but does not cure it. Continue to take levetiracetam even if you feel well. Do not stop taking levetiracetam without talking to your doctor. If you suddenly stop taking levetiracetam, your seizures may become worse. Your doctor will probably decrease your dose gradually.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Before taking levetiracetam,
- tell your doctor and pharmacist if you are allergic to levetiracetam or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had kidney disease.
- tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking levetiracetam, call your doctor. Do not breastfeed while you are taking levetiracetam
- you should know that levetiracetam may make you dizzy or drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
If it has only been a few hours since the time you were scheduled to take the dose, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Levetiracetam may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- drowsiness
- weakness
- unsteady walking
- coordination problems
- headache
- pain
- forgetfulness
- anxiety
- agitation or hostility
- dizziness
- moodiness
- nervousness
- numbness, burning, or tingling in the hands or feet
- loss of appetite
- vomiting
- diarrhea
- constipation
- changes in skin color
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
- depression
- hallucinating (hearing voices or seeing visions that do not exist)
- thoughts of killing yourself
- seizures that are worse or different than the seizures you had before
- fever, sore throat, and other signs of infection
- double vision
- itching
- rash
- swelling of the face
Levetiracetam may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- drowsiness
- agitation
- aggression
- decreased consciousness or loss of consciousness
- difficulty breathing
What other information should I know?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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