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Largactil Side Effects

Common Largactil Side Effects


The most commonly reported Largactil side effects (click to view or check a box to report):

Agitation (4)
Abnormal Behaviour (2)
Death (2)
Schizophrenia (2)
Sleep Disorder (2)
Platelet Count Decreased (2)
Gastric Haemorrhage (2)
Eating Disorder (2)
Pancreatitis (2)
Pancytopenia (1)
Poor Sucking Reflex (1)
Renal Tubular Disorder (1)
Jaundice (1)
Pregnancy (1)
Agitation Neonatal (1)
Self-injurious Ideation (1)
Hypertonia (1)
Hepatitis Cholestatic (1)
Hepatic Enzyme Increased (1)
Exposure During Pregnancy (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Largactil Side Effects Reported to FDA

The following Largactil reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Largactil on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Agitation Neonatal, Exposure During Pregnancy, Hypertonia, Poor Sucking Reflex
This is a report of a male patient (weight: NA) from FR, suffering from the following symptoms/conditions: exposure during pregnancy, who was treated with Largactil (dosage: NA, start time: Jul 21, 2009), combined with:
  • Stilnox
  • Methadone
  • Seresta
and developed a serious reaction and side effect(s). The consumer presented with:
  • Agitation Neonatal
  • Exposure During Pregnancy
  • Hypertonia
  • Poor Sucking Reflex
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Largactil treatment in male patients, resulting in agitation neonatal side effect. The patient was hospitalized.

Pregnancy, Abortion Spontaneous
This report suggests a potential Largactil Pregnancy, Abortion Spontaneous side effect(s) that can have serious consequences. A 38-year-old female patient (weight: NA) from FRANCE was diagnosed with the following symptoms/conditions: NA and used Largactil (dosage: NA) starting NS. Soon after starting Largactil the patient began experiencing various side effects, including:
  • Pregnancy
  • Abortion Spontaneous
Drugs used concurrently:
  • Heptamyl
  • Noctran
  • Abilify
Although Largactil demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as pregnancy, may still occur.

Pancreatitis, Eating Disorder, Platelet Count Decreased, Schizophrenia, Gastric Haemorrhage, Abnormal Behaviour, Agitation, Sleep Disorder
This Pancreatitis, Eating Disorder, Platelet Count Decreased, Schizophrenia, Gastric Haemorrhage, Abnormal Behaviour, Agitation, Sleep Disorder problem was reported by a physician from ALGERIA. A 33-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On Nov 01, 2009 this consumer started treatment with Largactil (dosage: NA). The following drugs were being taken at the same time:
  • Zyprexa (10 Mg, Daily (1/d))
  • Tranxene
  • Tegretol
When commencing Largactil, the patient experienced the following unwanted symptoms/side effects:
  • Pancreatitis
  • Eating Disorder
  • Platelet Count Decreased
  • Schizophrenia
  • Gastric Haemorrhage
  • Abnormal Behaviour
  • Agitation
  • Sleep Disorder
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as pancreatitis, may become evident only after a product is in use by the general population.

Sleep Disorder, Platelet Count Decreased, Abnormal Behaviour, Schizophrenia, Gastric Haemorrhage, Eating Disorder, Pancreatitis, Agitation
This is a report of a 33-year-old male patient (weight: NA) from ALGERIA. The patient developed the following symptoms/conditions: NA and was treated with Largactil (dosage: NA) starting Nov 01, 2009. Concurrently used drugs:
  • Zyprexa (10 Mg, Daily (1/d))
Soon after that, the consumer experienced the following side effects:
  • Sleep Disorder
  • Platelet Count Decreased
  • Abnormal Behaviour
  • Schizophrenia
  • Gastric Haemorrhage
  • Eating Disorder
  • Pancreatitis
  • Agitation
The patient was hospitalized. This opens a possibility that Largactil treatment could cause the above reactions, including sleep disorder, and some male subjects may be more susceptible.


Condition Aggravated, Agitation, Anxiety, Self-injurious Ideation
A 25-year-old male patient (weight: NA) from AUSTRALIA with the following symptoms/conditions: NA started Largactil treatment (dosage: NA) on NS. Soon after starting Largactil treatment, the subject experienced various side effects, including:
  • Condition Aggravated
  • Agitation
  • Anxiety
  • Self-injurious Ideation
Concurrently used drugs:
  • Pristiq
  • Xanax (4-6 Tablets Each Day)
  • Valium
This finding indicates that some male patients could be more vulnerable to Largactil.

Pancytopenia, Renal Tubular Disorder
A 59-year-old male patient from FRANCE (weight: NA) experienced symptoms, such as: NA and was treated with Largactil(dosage: NA). The treatment was initiated on May 31, 2010. After that a consumer reported the following side effect(s):
  • Pancytopenia
  • Renal Tubular Disorder
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Largactil efficacy:
  • Kardegic
  • Zolpidem
  • Alkeran
  • Acupan
  • Coversyl /fra/
  • Bisoprolol
  • Furosemide
  • Neulasta
The patient was hospitalized.

Coma Hepatic, Hepatic Enzyme Increased, Hepatitis Cholestatic, Jaundice, Thrombocytopenia
In this report, Largactil was administered for the following condition: NA.A 57-year-old male consumer from FRANCE (weight: NA) started Largactil treatment (dosage: Unk) on Jun 14, 2006.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Coma Hepatic
  • Hepatic Enzyme Increased
  • Hepatitis Cholestatic
  • Jaundice
  • Thrombocytopenia
A possible interaction with other drugs could have contributed to this reaction:
  • Amitriptyline Hcl (Unk)
  • Gemzar
  • Eloxatin
The patient was hospitalized.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Largactil treatment could be related to the listed above side effect(s).



Top 10 Largactil Side Effects for Women

Women Side EffectsReports
Abortion Spontaneous 1
Pregnancy 1

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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    Largactil Safety Alerts, Active Ingredients, Usage Information

    More About Largactil

    Side Effects reported to FDA: 7

    Largactil safety alerts: No

    Reported deaths: 3

    Reported hospitalizations: 5

    Latest Largactil clinical trials

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