Leflunomide Side Effects summary

Total Leflunomide reports: 129. View

Leflunomide FDA safety alerts: 2003 .

Reported deaths: 9

Reported hospitalizations: 54.

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Recently reported Leflunomide Side Effects


Common Leflunomide Side Effects
Hepatotoxicity 10
Dyspnoea 9
Weight decreased 7
Alanine aminotransferase increased 6
Condition aggravated 6
Cutaneous lupus erythematosus 6
Leukopenia 6
Liver function test abnormal 6
Nausea  What is  Nausea                                                                                                                                                                                                  6
Off label use 6
Pyrexia 6
Anaemia 5
Dizziness  What is  Dizziness                                                                                                                                                                                               5
Lung neoplasm 5
Progressive multifocal leukoencephalopathy 5
Aphasia  What is  Aphasia                                                                                                                                                                                                 4
Arthralgia 4
Blood pressure increased 4
Chronic obstructive pulmonary disease 4
Diarrhoea 4
Fatigue 4
Hemiparesis 4
Hepatic enzyme increased 4
Hepatic failure 4
Interstitial lung disease 4
Jaundice  What is  Jaundice                                                                                                                                                                                                4
Myelodysplastic syndrome 4
Pneumonia  What is  Pneumonia                                                                                                                                                                                               4
Thrombocytopenia 4
Thrombotic microangiopathy 4

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Questions to date: 1. Page 1 of 1.

Evelyn Jacob   Vancouver B.C. 

10:02am on Monday, August 31st, 2009

i have a diagnosis of RA for the past 27 years. I was recently prescribed Leflunomide 10 mg. by my rheumatologist. After about 2 weeks, all the pain I was experiencing stopped. It was like a miracle! This continued for many weeks.

The dug is very ...
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Leflunomide Side Effects Report #5205829-8
Consumer or non-health professional from UNITED STATES reported Leflunomide side effect on Jan 05, 2007. Female patient, 55 years of age, weighting 145.0 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: coagulopathy, haemorrhagic stroke, hepatic failure, hepatotoxicity, influenza like illness, liver disorder, lung disorder, no therapeutic response. Leflunomide dosage: 10 MG DAILY PO. During the same period patient was treated with HUMIRA. Patient died on 11/23/2005.



Leflunomide Side Effects Report #5212784-3
Leflunomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 18, 2007. Female patient, weighting 350.0 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: asthma What is  asthma, blister, pyrexia. Leflunomide dosage: unknown. During the same period patient was treated with LISINOPRIL, HYDROCHLOROTHIAZIDE, PREDNISONE, METFORMIN, ASPIRIN. Patient recovered.



Leflunomide Side Effects Report #5221842-9
Pharmacist from UNITED STATES reported Leflunomide side effect on Jan 25, 2007. Male patient, 76 years of age, weighting 162.0 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: epistaxis, faeces discoloured, fatigue, haemoglobin decreased, liver function test abnormal, nausea What is  nausea, pancytopenia, platelet count decreased. Leflunomide dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5224957-4
Leflunomide side effect was reported by a Physician from FRANCE on June 30, 2005. Male patient, 30 years of age, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: pregnancy of partner. Leflunomide dosage: unknown. During the same period patient was treated with NSAID. Patient recovered.




Leflunomide Side Effects Report #5236881-1
Consumer or non-health professional from reported Leflunomide side effect on Jan 31, 2007. Female patient, 40 years of age, was diagnosed with psoriatic arthropathy, arthralgia, dyspepsia and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: psoriasis. Leflunomide dosage: unknown. During the same period patient was treated with ACETAMINOPHEN AND CODEINE PHOSPHATE, IBUPROFEN, LANSOPRAZOLE. Patient recovered.



Leflunomide Side Effects Report #5247680-9
Leflunomide side effect was reported by a Consumer or non-health professional from on Feb 20, 2007. Female patient, 40 years of age, was diagnosed with dyspepsia and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: psoriasis. Leflunomide dosage: unknown. During the same period patient was treated with ACETAMINOPHEN W, IBUPROFEN, LANSOPRAZOLE. Patient recovered.



Leflunomide Side Effects Report #5262507-7
Consumer or non-health professional from reported Leflunomide side effect on Feb 27, 2007. Female patient, 24 years of age, weighting 123.2 lb, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased. Leflunomide dosage: unknown. During the same period patient was treated with ACECLOFENAC, CYCLOSPORINE. Patient recovered.



Leflunomide Side Effects Report #5277207-7
Leflunomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 22, 2007. Male patient, 43 years of age, weighting 200.0 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: disease recurrence, rheumatoid arthritis What is  rheumatoid arthritis. Leflunomide dosage: 20MG DAILY PO. Patient recovered.



Leflunomide Side Effects Report #5301489-6
Health Professional from UNITED STATES reported Leflunomide side effect on Mar 28, 2007. Female patient, 35 years of age, weighting 242.1 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: abortion spontaneous, pregnancy What is  pregnancy. Leflunomide dosage: 20 MG, QD, ORAL. During the same period patient was treated with PRENATAL VITAMINS, PLAQUENIL, PREDNISONE, VICODIN, AMBIEN, SYTHROID, TYLENOL. Patient recovered.




Leflunomide Side Effects Report #5370254-6
Leflunomide side effect was reported by a Physician from UNITED STATES on June 25, 2007. Female patient, weighting 154.0 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: cerebrovascular accident, coagulopathy, hepatic failure, nausea What is  nausea, pulmonary embolism What is  pulmonary embolism. Leflunomide dosage: 10MG. During the same period patient was treated with HUMIRA. Patient died on 11/25/2006.



Leflunomide Side Effects Report #5063996-3
Consumer or non-health professional from UNITED STATES reported Leflunomide side effect on May 18, 2006. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: alopecia, anxiety What is  anxiety, blood glucose increased, blood pressure increased, chest pain What is  chest pain, constipation What is  constipation, coronary artery disease What is  coronary artery disease, diarrhoea, dizziness What is  dizziness. Leflunomide dosage: unknown. During the same period patient was treated with ARAVA, ASPIRIN, PREDNISONE, HYZAAR, TOPROL, AMBIEN, LASIX, ESOMEPRAZOLE MAGNESIUM. Patient recovered.



Leflunomide Side Effects Report #5072222-0
Leflunomide side effect was reported by a Physician from AUSTRIA on July 26, 2006. Female patient was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: infection What is  infection, leukopenia, myelodysplastic syndrome, pyrexia. Leflunomide dosage: unknown. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5079193-1
Physician from AUSTRIA reported Leflunomide side effect on July 26, 2006. Female patient, 66 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: infection What is  infection, leukopenia, mucosal inflammation, myelodysplastic syndrome, pyrexia, sepsis What is  sepsis, thrombocytopenia. Leflunomide dosage: unknown. During the same period patient was treated with ATACAND HCT, THYREX, PANTOPRAZOLE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5087328-X
Leflunomide side effect was reported by a Pharmacist from UNITED STATES on Aug 23, 2006. Female patient, 58 years of age, weighting 262.4 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: angioneurotic oedema, asthma What is  asthma, condition aggravated, dyspnoea, urticaria. Leflunomide dosage: 10 MG DAILY PO. Patient was hospitalized. Patient recovered.




Leflunomide Side Effects Report #5141606-4
Pharmacist from UNITED STATES reported Leflunomide side effect on Oct 23, 2006. Female patient, 71 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: abdominal pain upper, arrhythmia What is  arrhythmia, arthralgia, arthritis What is  arthritis, condition aggravated, diarrhoea, erythema, joint swelling. Leflunomide dosage: 20 MG, QD, ORAL. During the same period patient was treated with ARAVA, LASIX, POTASSIUM CHLORIDE, PREDNISONE, PRILOSEC, CARDIZEM, SYNTRHOID, XOPENEX. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5154138-4
Leflunomide side effect was reported by a Consumer or non-health professional from on Apr 04, 2005. Male patient, 41 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: pregnancy of partner. Leflunomide dosage: unknown. Patient recovered.



Leflunomide Side Effects Report #5193815-6
Consumer or non-health professional from reported Leflunomide side effect on Dec 19, 2006. Male patient, 66 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis, anxiety What is  anxiety, depression What is  depression, hereditary spherocytosis, hypertension, pain What is  pain and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, diarrhoea, gamma-glutamyltransferase increased, international normalised ratio increased, jaundice What is  jaundice, liver function test abnormal, urine analysis abnormal. Leflunomide dosage: unknown. During the same period patient was treated with SULFASALAZINE, CITALOPRAM HYDROBROMIDE, CITALOPRAM HYDROBROMIDE, FOLIC ACID, KENALOG, LOSARTAN POTASSIUM, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5399322-X
Leflunomide side effect was reported by a Consumer or non-health professional from on July 23, 2007. Female patient, child 2 years of age, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: accidental exposure, accidental overdose, transaminases increased. Leflunomide dosage: unknown. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5402308-X
Consumer or non-health professional from UNITED KINGDOM reported Leflunomide side effect on July 23, 2007. Male patient, 69 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: alveolitis allergic, dyspnoea. Leflunomide dosage: unknown. Patient was hospitalized. Patient recovered.




Leflunomide Side Effects Report #5402312-1
Leflunomide side effect was reported by a Consumer or non-health professional from on July 25, 2007. Female patient, child 2 years of age, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: accidental exposure, accidental overdose, transaminases increased. Leflunomide dosage: unknown. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5409585-X
Consumer or non-health professional from reported Leflunomide side effect on Aug 01, 2007. Female patient, 68 years of age, weighting 146.2 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis, prophylaxis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: lung abscess, pulmonary embolism What is  pulmonary embolism. Leflunomide dosage: unknown. During the same period patient was treated with HUMIRA, DOSULEPIN, FOSAMAX, OMEPRAZOLE, PARACETAMOL, PREDNISOLONE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5447464-2
Leflunomide side effect was reported by a Physician from AUSTRIA on Aug 21, 2007. Female patient, 64 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: bone marrow toxicity, leukopenia, lymphopenia, myelodysplastic syndrome, neutropenia, pyrexia, stomatitis. Leflunomide dosage: 10 MG, 20 MG. During the same period patient was treated with METAMIZOLE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5451971-6
Physician from UNITED KINGDOM reported Leflunomide side effect on Sept 03, 2007. Male patient was treated with Leflunomide. After drug was administered, patient experienced the following side effects: cerebral palsy, multiple congenital abnormalities, muscle spasticity, premature baby. Leflunomide dosage: unknown. During the same period patient was treated with CHOLESTYRAMINE RESIN. Patient recovered.



Leflunomide Side Effects Report #5479550-5
Leflunomide side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 23, 2007. Male patient, 69 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: alveolitis allergic, dyspnoea. Leflunomide dosage: unknown. During the same period patient was treated with ETODOLAC, RANITIDINE, PARACETAMOL, NIFEDIPINE. Patient was hospitalized. Patient recovered.




Leflunomide Side Effects Report #5486035-9
Consumer or non-health professional from SPAIN reported Leflunomide side effect on Oct 01, 2007. Female patient, 72 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: angioedema, encephalopathy, multi-organ failure, shock, stevens-johnson syndrome, transaminases increased. Leflunomide dosage: 20 MG QD PO. During the same period patient was treated with CAPTOPRIL, LORAZEPAM, OMEPRAZOLE, NAPROXEN, EQUISETUM ARVENSE, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient died.



Leflunomide Side Effects Report #5487578-4
Leflunomide side effect was reported by a Consumer or non-health professional from ESTONIA on Sept 13, 2007. Female patient, 37 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: no adverse reaction, pregnancy What is  pregnancy. Leflunomide dosage: unknown. Patient recovered.



Leflunomide Side Effects Report #5494977-3
Consumer or non-health professional from reported Leflunomide side effect on Oct 17, 2007. Male patient, 72 years of age, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: hepatotoxicity, jaundice What is  jaundice. Leflunomide dosage: unknown. During the same period patient was treated with TRIMEPRAZINE, CELECOXIB, OMEPRAZOLE, SERETIDE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5500076-4
Leflunomide side effect was reported by a Consumer or non-health professional from INDIA on Oct 09, 2007. Female patient, 36 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: leprosy, treatment noncompliance, tuberculosis What is  tuberculosis. Leflunomide dosage: 20MG. During the same period patient was treated with PREDNISOLONE. Patient recovered.



Leflunomide Side Effects Report #5506199-8
Pharmacist from UNITED STATES reported Leflunomide side effect on Nov 02, 2007. Male patient, 82 years of age, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: headache What is  headache. Leflunomide dosage: 10MG EVERY DAY PO. Patient recovered.




Leflunomide Side Effects Report #5523292-4
Leflunomide side effect was reported by a Consumer or non-health professional from on Nov 15, 2007. Female patient, 74 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: hepatotoxicity, rash What is  rash. Leflunomide dosage: unknown. During the same period patient was treated with AMLODIPINE, ATENOLOL, AZATHIOPRINE, OMEPRAZOLE, PREDNISOLONE, RISEDRONATE, SIMVASTATIN. Patient recovered.



Leflunomide Side Effects Report #5523293-6
Consumer or non-health professional from reported Leflunomide side effect on Nov 15, 2007. Female patient, 80 years of age, weighting 113.2 lb, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: contusion, nausea What is  nausea, weight decreased. Leflunomide dosage: unknown. During the same period patient was treated with CELEBREX. Patient recovered.



Leflunomide Side Effects Report #5523295-X
Leflunomide side effect was reported by a Consumer or non-health professional from on Nov 13, 2007. Male patient, 72 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis, duodenal ulcer, pain What is  pain, asthma What is  asthma and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: liver function test abnormal. Leflunomide dosage: unknown. During the same period patient was treated with TRIMEPRAZINE, CELECOXIB, FOLIC ACID, OMEPRAZOLE, PARACETAMOL, SERETIDE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5525861-4
Consumer or non-health professional from reported Leflunomide side effect on Nov 16, 2007. Female patient, 54 years of age, was treated with Leflunomide. After drug was administered, patient experienced the following side effects: necrotising retinitis. Leflunomide dosage: unknown. During the same period patient was treated with PREDNISOLONE, AMITRIPTYLINE, ASPIRIN, ATENOLOL, BENDROFLUMETHIAZIDE, FLUOXETINE, LEVOTHYROXINE, NAPROXEN. Patient was hospitalized and became disabled. Patient recovered.



Leflunomide Side Effects Report #5552647-7
Leflunomide side effect was reported by a Consumer or non-health professional from NETHERLANDS on Nov 29, 2007. Female patient, 60 years of age, was diagnosed with psoriatic arthropathy and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: anaemia, enterobacter infection, haemophilus infection, pneumonia What is  pneumonia, pseudomonas infection, pulmonary cavitation, staphylococcal infection What is  staphylococcal infection. Leflunomide dosage: 20 MG. During the same period patient was treated with METHOTREXATE, PREDNISONE, HYDROXYCHLOROQUINE, SULPHASALAZINE. Patient recovered.




Leflunomide Side Effects Report #5552677-5
Consumer or non-health professional from NETHERLANDS reported Leflunomide side effect on Nov 29, 2007. Female patient, 68 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: anaemia, enterobacter infection, lung infection, malaise, pneumonia What is  pneumonia, pulmonary cavitation. Leflunomide dosage: 20 MG. During the same period patient was treated with METHOTREXATE, PREDNISONE, HYDROXYCHLOROQUINE. Patient recovered.



Leflunomide Side Effects Report #5552731-8
Leflunomide side effect was reported by a Consumer or non-health professional from NETHERLANDS on Nov 29, 2007. Male patient, 78 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: anaemia, enterobacter pneumonia, pneumonia staphylococcal, pulmonary cavitation. Leflunomide dosage: 20 MG. During the same period patient was treated with METHOTREXATE, PREDNISONE. Patient recovered.



Leflunomide Side Effects Report #5552875-0
Consumer or non-health professional from NETHERLANDS reported Leflunomide side effect on Nov 29, 2007. Male patient, 57 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: actinomycotic pulmonary infection, anaemia, lobar pneumonia. Leflunomide dosage: 20 MG. During the same period patient was treated with METHOTREXATE, PREDNISONE. Patient recovered.



Leflunomide Side Effects Report #5593101-6
Leflunomide side effect was reported by a Consumer or non-health professional from on Jan 10, 2008. Female patient, 80 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis, pain What is  pain and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: interstitial lung disease. Leflunomide dosage: unknown. During the same period patient was treated with GABAPENTIN, LANSOPRAZOLE, PREDNISOLONE, TRAMADOL. Patient died on 09/25/2007.



Leflunomide Side Effects Report #5606112-9
Consumer or non-health professional from AUSTRALIA reported Leflunomide side effect on Jan 08, 2008. Female patient, 60 years of age, was diagnosed with musculoskeletal pain and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: liver function test abnormal, peripheral sensorimotor neuropathy. Leflunomide dosage: 20 MG/DAY. During the same period patient was treated with METHOTREXATE. Patient recovered.




Leflunomide Side Effects Report #5606113-0
Leflunomide side effect was reported by a Consumer or non-health professional from AUSTRALIA on Jan 08, 2008. Male patient, 65 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: hepatitis What is  hepatitis, peripheral sensorimotor neuropathy. Leflunomide dosage: 20 MG/DAY. During the same period patient was treated with METHOTREXATE, PREDNISONE. Patient recovered.



Leflunomide Side Effects Report #5610898-7
Consumer or non-health professional from JAPAN reported Leflunomide side effect on Jan 23, 2008. Female patient, 53 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: myositis What is  myositis. Leflunomide dosage: unknown. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5622997-4
Leflunomide side effect was reported by a Consumer or non-health professional from JAPAN on Feb 01, 2008. Female patient, 53 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: myositis What is  myositis. Leflunomide dosage: unknown. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5624828-5
Consumer or non-health professional from reported Leflunomide side effect on Feb 06, 2008. Male patient, 72 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis, duodenal ulcer, asthma What is  asthma, pain What is  pain and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: hepatotoxicity, jaundice What is  jaundice, liver function test abnormal. Leflunomide dosage: unknown. During the same period patient was treated with TRIMEPRAZINE, CELECOXIB, OMEPRAZOLE, SERETIDE, FOLIC ACID, PARACETAMOL. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5626349-2
Leflunomide side effect was reported by a Consumer or non-health professional from GERMANY on Feb 08, 2008. Female patient, 42 years of age, was diagnosed with arthritis What is  arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: condition aggravated, cutaneous lupus erythematosus, scab What is  scab, skin ulcer. Leflunomide dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5631751-9
Physician from GERMANY reported Leflunomide side effect on Feb 01, 2008. Female patient, 42 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: condition aggravated, cutaneous lupus erythematosus, leukopenia, mucosal ulceration, rheumatoid arthritis What is  rheumatoid arthritis. Leflunomide dosage: 100 MG, QD,; 20 MG, QD,. During the same period patient was treated with PREDNISOLONE, GLUCOCORTICOSTEROIDS. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5638367-9
Leflunomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 15, 2008. Male patient, weighting 220.9 lb, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis, blood pressure What is  blood pressure and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: abdominal pain What is  abdominal pain, accidental overdose, anxiety What is  anxiety, blood urine present, depression What is  depression, diplopia, dizziness What is  dizziness, glucose urine present, hallucination. Leflunomide dosage: unknown. During the same period patient was treated with METFORMIN, VERAPAMIL, NITROGLYCERIN, CATAPRES, ASPIRIN, PLAVIX, GABAPENTIN, PREDNISONE. Patient recovered.



Leflunomide Side Effects Report #5652175-4
Consumer or non-health professional from FRANCE reported Leflunomide side effect on Feb 18, 2008. Female patient, 34 years of age, was diagnosed with juvenile arthritis, therapeutic procedure and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: hepatic fibrosis, hepatic lesion, hepatic necrosis, hepatitis fulminant, hepatomegaly, hepatotoxicity, vitamin k deficiency. Leflunomide dosage: 20 MG/DAY. During the same period patient was treated with CHOLESTYRAMINE, ACETAMINOPHEN W. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5659525-3
Leflunomide side effect was reported by a Health Professional from TURKEY on Feb 27, 2008. Male patient, 64 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: hypoglycaemia. Leflunomide dosage: unknown. During the same period patient was treated with PREDNISOLONE, SULFASALAZINE, METHOTREXATE, HYDROXYCHLOROQUINE SULPHATE. Patient was hospitalized. Patient recovered.



Leflunomide Side Effects Report #5676746-4
Physician from FRANCE reported Leflunomide side effect on Mar 03, 2008. Female patient, 34 years of age, was diagnosed with juvenile arthritis, therapeutic procedure and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: blood fibrinogen decreased, hepatic fibrosis, hepatic necrosis, hepatitis fulminant, hepatomegaly, hepatotoxicity, prothrombin level abnormal, serum ferritin increased, vitamin k deficiency. Leflunomide dosage: 20 MG/DAY. During the same period patient was treated with CHOLESTYRAMINE, ACETAMINOPHEN W, PREDNISONE, NICARDECREASEINE, CANDESARTAN CILEXETIL, CALCIUM CARBONATE, CHOLECALCIFEROL. Patient was hospitalized. Patient recovered.




Leflunomide Side Effects Report #5688171-0
Leflunomide side effect was reported by a Health Professional from UNITED KINGDOM on Mar 14, 2008. Female patient, 73 years of age, was diagnosed with rheumatoid arthritis What is  rheumatoid arthritis and was treated with Leflunomide. After drug was administered, patient experienced the following side effects: anaemia, bronchopneumonia, cardiac failure, chronic obstructive pulmonary disease, cytomegalovirus infection What is  cytomegalovirus infection, electrocardiogram p pulmonale, fatigue, hepatic function abnormal. Leflunomide dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHOTREXATE, PREDNISOLONE, STEROIDS NOS, STEROIDS NOS, SULFASALAZINE. Patient died.



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