Lepirudin Side Effects summary

Total Lepirudin reports: 20. View

Lepirudin FDA safety alerts: No.

Reported deaths: 5

Reported hospitalizations: 9.

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Recently reported Lepirudin Side Effects


Common Lepirudin Side Effects
Haemorrhage 30%
Activated partial thromboplastin time prolonged 25%
Catheter site haemorrhage 15%
Haemorrhagic anaemia 15%
Intra-abdominal haematoma 15%
Pelvic haematoma 15%
Adrenal haemorrhage 10%
Cerebral haemorrhage 10%
Confusional state 10%
Haemoglobin decreased 10%
Hypotension 10%
Infusion related reaction 10%
International normalised ratio increased 10%
Addison's disease  What is  Addison's disease                                                                                                                                                                                       5%
Adrenocortical insufficiency acute 5%
Anaemia 5%
Anaphylactic reaction 5%
Asthenia 5%
Blood creatinine increased 5%
Bronchopulmonary dysplasia 5%
Cardio-respiratory arrest 5%
Chest pain  What is  Chest pain                                                                                                                                                                                              5%
Condition aggravated 5%
Convulsion 5%
Creatinine renal clearance decreased 5%
Diarrhoea 5%
Dysgeusia 5%
Epistaxis 5%
Fatigue 5%
Haemodialysis 5%
Haemoptysis 5%
Hypercoagulation 5%
Lethargy 5%
Loss of consciousness 5%
Mouth haemorrhage 5%
No adverse event 5%
Oesophageal haemorrhage 5%
Overdose 5%
Pupil fixed 5%
Pyrexia 5%
Renal failure acute 5%
Septic shock 5%
Thrombosis 5%
Ventricular fibrillation 5%

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Lepirudin Side Effects reported on Patientsville.com

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Lepirudin Side Effects reported to FDA

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Lepirudin Side Effects Report #5206911-1
Consumer or non-health professional from UNITED STATES reported Lepirudin side effect on Jan 05, 2007. Female patient, 84 years of age, was diagnosed with deep vein thrombosis What is  deep vein thrombosis, pulmonary embolism What is  pulmonary embolism and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood creatinine increased, creatinine renal clearance decreased, haemoglobin decreased. Lepirudin dosage: unknown. During the same period patient was treated with AMIODARONE, FUROSEMIDE, FENTANYL TRANSDERMAL SYSTEM, AZTREONAM, HYDRALAZINE, METOPROLOL SUCCINATE, RANITIDINE. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #5223203-5
Lepirudin side effect was reported by a Health Professional from SPAIN on Jan 08, 2007. Female patient, 76 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: chest pain What is  chest pain, haemodialysis, hypotension, overdose, thrombosis. Lepirudin dosage: 0.05 MG/KG, EVERY 2D, IV BOLUS. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #5064238-5
Pharmacist from UNITED STATES reported Lepirudin side effect on July 26, 2006. Male patient, 68 years of age, weighting 185.2 lb, was diagnosed with thrombosis prophylaxis and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, pupil fixed. Lepirudin dosage: unknown. During the same period patient was treated with ACETAMINOPHEN ALCOHOL FREE, ENTERAL TUBE, ALBUTEROL SULPHATE AND IPRATROPIUM BROMIDE, BISACODYL, CALCIUM CARBONATE, CASPOFUNGIN, DEXTROSE, DILTIAZEM. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #5144260-0
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on Nov 02, 2006. Female patient, 57 years of age, weighting 194.0 lb, was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardio-respiratory arrest, catheter site haemorrhage, infusion related reaction, ventricular fibrillation. Lepirudin dosage: 0.2 MG/KG -17.6 MG TOTAL NOW IV BOLUS. Patient recovered.




Lepirudin Side Effects Report #5426099-1
Pharmacist from UNITED STATES reported Lepirudin side effect on Aug 23, 2007. Female patient, 26 years of age, was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, catheter site haemorrhage, condition aggravated, haemoptysis. Lepirudin dosage: unknown. Patient recovered.



Lepirudin Side Effects Report #5594452-1
Lepirudin side effect was reported by a Health Professional from FRANCE on Jan 03, 2008. Male patient, 33 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: addison's disease What is  addison's disease, adrenal haemorrhage, asthenia, confusional state, diarrhoea, pyrexia. Lepirudin dosage: unknown. Patient recovered.



Lepirudin Side Effects Report #5709666-7
Health Professional from UNITED STATES reported Lepirudin side effect on Apr 03, 2008. Female patient, 26 years of age, was diagnosed with pulmonary hypertension What is  pulmonary hypertension and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: intra-abdominal haematoma, pelvic haematoma. Lepirudin dosage: unknown. During the same period patient was treated with EPHEDRINE SUL CAP, ENOXAPARIN, AMLODIPINE, EPIDURAL ANAESTHESIA, EPOPROSTENOL, WARFARIN. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #5766906-6
Lepirudin side effect was reported by a Health Professional from FRANCE on May 30, 2008. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: anaemia, haemorrhage. Lepirudin dosage: unknown. Patient died on 05/16/2008.



Lepirudin Side Effects Report #5840435-3
Health Professional from FRANCE reported Lepirudin side effect on June 06, 2008. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: haemorrhage, haemorrhagic anaemia. Lepirudin dosage: unknown. During the same period patient was treated with ORGARAN. Patient died on 05/16/2008.




Lepirudin Side Effects Report #5841663-3
Lepirudin side effect was reported by a Health Professional from FRANCE on June 06, 2008. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: haemorrhage, haemorrhagic anaemia. Lepirudin dosage: unknown. During the same period patient was treated with ORGARAN. Patient died on 05/16/2008.



Lepirudin Side Effects Report #5979904-4
Health Professional from FRANCE reported Lepirudin side effect on June 06, 2008. Female patient, 75 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: haemorrhage, haemorrhagic anaemia, renal failure acute, septic shock. Lepirudin dosage: unknown. During the same period patient was treated with ORGARAN. Patient died on 05/16/2008.



Lepirudin Side Effects Report #6031194-2
Lepirudin side effect was reported by a Health Professional from UNITED STATES on Apr 03, 2008. Female patient, 26 years of age, was diagnosed with pulmonary arterial hypertension and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: intra-abdominal haematoma, pelvic haematoma. Lepirudin dosage: unknown. During the same period patient was treated with EPHEDRINE, ENOXAPARIN, AMLODIPINE, EPIDURAL ANAESTHESIA, EPOPROSTENOL, WARFARIN. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #6045056-8
Health Professional from UNITED STATES reported Lepirudin side effect on Jan 15, 2009. Female patient, 26 years of age, was diagnosed with pulmonary arterial hypertension and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: haemoglobin decreased, intra-abdominal haematoma, pelvic haematoma. Lepirudin dosage: unknown. During the same period patient was treated with EPHEDRINE, ENOXAPARIN, AMLODIPINE, EPIDURAL ANAESTHESIA, EPOPROSTENOL, WARFARIN. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #6114455-8
Lepirudin side effect was reported by a Health Professional from UNITED STATES on Feb 19, 2009. Female patient, weighting 1.10 lb, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: bronchopulmonary dysplasia. Lepirudin dosage: unknown. Patient recovered.




Lepirudin Side Effects Report #6118896-4
Health Professional from UNITED STATES reported Lepirudin side effect on Feb 19, 2009. Female patient, 21 years of age, was diagnosed with heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: no adverse event. Lepirudin dosage: unknown. Patient recovered.



Lepirudin Side Effects Report #4748530-7
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on Aug 18, 2005. Male patient, 64 years of age, weighting 165.3 lb, was diagnosed with deep vein thrombosis What is  deep vein thrombosis, heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, oesophageal haemorrhage. Lepirudin dosage: unknown. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #4848052-9
Pharmacist from UNITED STATES reported Lepirudin side effect on Dec 07, 2005. Female patient, 58 years of age, weighting 253.0 lb, was diagnosed with deep vein thrombosis What is  deep vein thrombosis, heparin-induced thrombocytopenia and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, convulsion. Lepirudin dosage: 0.0225 MG/KG/HR. Patient died on 10/02/2005.



Lepirudin Side Effects Report #4889778-0
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on Jan 23, 2006. Male patient, 65 years of age, weighting 145.3 lb, was diagnosed with pulmonary embolism What is  pulmonary embolism and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: adrenal haemorrhage, adrenocortical insufficiency acute, anaphylactic reaction, dysgeusia, fatigue, hypercoagulation, hypotension, lethargy, loss of consciousness. Lepirudin dosage: unknown. Patient was hospitalized. Patient recovered.



Lepirudin Side Effects Report #5013991-5
Pharmacist from UNITED STATES reported Lepirudin side effect on May 26, 2006. Female patient, 44 years of age, weighting 276.9 lb, was diagnosed with heparin-induced thrombocytopenia, thrombosis and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: infusion related reaction, international normalised ratio increased. Lepirudin dosage: unknown. During the same period patient was treated with LEPIRUDIN INFUSION. Patient was hospitalized. Patient recovered.




Lepirudin Side Effects Report #5015387-9
Lepirudin side effect was reported by a Pharmacist from UNITED STATES on May 30, 2006. Female patient, 88 years of age, was diagnosed with thrombosis and was treated with Lepirudin. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, catheter site haemorrhage, confusional state, epistaxis, international normalised ratio increased, mouth haemorrhage. Lepirudin dosage: 0.15MG/KG/HR. Patient recovered.





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