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LEUCOVORIN Safety Reports

Total LEUCOVORIN reports: 112.
LEUCOVORIN FDA safety alerts: No.
Reported deaths: 34    Reported hospitalizations: 66.
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Health Professional from JAPAN reported LEUCOVORIN problem on Mar 30, 2006. Male patient, weighting 132.3 lb, was diagnosed with rectal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: erythema. LEUCOVORIN dosage: 100 MG/BODY=63.3 MG/M2. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient recovered.

LEUCOVORIN problem was reported by a Consumer or non-health professional from on Nov 28, 2006. Male patient, 20 years of age, was diagnosed with colon cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: acute abdomen, escherichia infection, hypertriglyceridaemia, impaired healing, peritonitis bacterial. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, IRINOTECAN, BEVACIZUMAB. Patient was hospitalized. Patient recovered.

Health Professional from GERMANY reported LEUCOVORIN problem on Nov 15, 2006. Female patient, weighting 141.1 lb, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: chest pain, nausea, splenic rupture, vomiting. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELOXATIN, AVASTIN. Patient was hospitalized. Patient recovered.

LEUCOVORIN problem was reported by a Physician from JAPAN on Nov 06, 2006. Male patient was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease, neutropenia. LEUCOVORIN dosage: 275MG/M2 AS INFUSION. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient died on 11/15/2006.

Health Professional from JAPAN reported LEUCOVORIN problem on Feb 21, 2006. Male patient, weighting 116.8 lb, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: anorexia, cardio-respiratory arrest, decreased appetite, dehydration, diarrhoea, disease progression, haemoglobin decreased, post procedural haemorrhage. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient died on 10/27/2005.

LEUCOVORIN problem was reported by a Health Professional from UNITED STATES on Dec 12, 2005. Male patient, 70 years of age, was diagnosed with colorectal cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: hypocalcaemia, hypomagnesaemia. LEUCOVORIN dosage: 775 MG/M2/IV. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from reported LEUCOVORIN problem on July 06, 2007. Female patient, 76 years of age, was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, lung cancer metastatic, mucosal inflammation, parotid gland enlargement, pyrexia, rectal cancer, salivary gland cancer, skin nodule. LEUCOVORIN dosage: 250 MG/M2 Q14D X 2 DOSES. During the same period patient was treated with OXALIPLATIN, RALTITREXED, FLUOROURACIL. Patient was hospitalized. Patient died on 05/01/2006.

LEUCOVORIN problem was reported by a Health Professional from UNITED STATES on June 29, 2007. Male patient, 68 years of age, weighting 140.0 lb, was diagnosed with colorectal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea, febrile neutropenia. LEUCOVORIN dosage: 625 MG TOTAL. During the same period patient was treated with FLUOROURACIL, BEVACIZUMAB, OXALIPLATIN, AVAPRO, HYTRIN, NEXIUM. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from reported LEUCOVORIN problem on July 17, 2007. Male patient, 66 years of age, was diagnosed with colon cancer stage iii and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: cholestasis, jaundice, liver disorder, liver function test abnormal. LEUCOVORIN dosage: 35 MG/WEEK X 30 WEEKS. During the same period patient was treated with FLUOROURACIL. Patient recovered.

LEUCOVORIN problem was reported by a Consumer or non-health professional from on July 17, 2007. Male patient, 62 years of age, was diagnosed with colorectal cancer stage iii and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: chromaturia, jaundice, liver disorder, liver function test abnormal. LEUCOVORIN dosage: 36 MG QD X 5 DAYS. During the same period patient was treated with FLUOROURACIL. Patient recovered.

Consumer or non-health professional from UNITED STATES reported LEUCOVORIN problem on July 19, 2007. Male patient, 63 years of age, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: agitation, anxiety, chromaturia, haemolytic anaemia, pain. LEUCOVORIN dosage: unknown. During the same period patient was treated with OXALIPLATIN, ELOXATIN, FLUOROURACIL, XELODA. Patient was hospitalized. Patient recovered.

LEUCOVORIN problem was reported by a Consumer or non-health professional from UNITED STATES on July 20, 2007. Male patient, 66 years of age, was diagnosed with colorectal cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: back pain, hypertension, musculoskeletal pain, red blood cell count increased. LEUCOVORIN dosage: 864MG/IV/EVERY 2 WEEKS. Patient was hospitalized. Patient recovered.

Physician from JAPAN reported LEUCOVORIN problem on July 31, 2007. Male patient, 57 years of age, was diagnosed with large intestine carcinoma and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: venoocclusive liver disease. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, ELPLAT. Patient recovered.

LEUCOVORIN problem was reported by a Physician from UNITED STATES on Aug 03, 2007. Male patient, 17 years of age, was diagnosed with nasopharyngeal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: dental caries, dry mouth, fibrosis, osteonecrosis, temporomandibular joint syndrome. LEUCOVORIN dosage: 25 MG/M2 PER_CYCLE. During the same period patient was treated with METHOTREXATE, CISPLATIN, FLUOROURACIL. Patient recovered.

Physician from UNITED STATES reported LEUCOVORIN problem on Aug 03, 2007. Male patient, 16 years of age, was diagnosed with nasopharyngeal cancer stage iii and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: blood luteinising hormone decreased, disease progression, dry mouth, hypothyroidism, myopia, otorrhoea, psychotic disorder. LEUCOVORIN dosage: 25 MG/M2 PER_CYCLE. During the same period patient was treated with METHOTREXATE, CISPLATIN, FLUOROURACIL. Patient recovered.

LEUCOVORIN problem was reported by a Physician from UNITED STATES on Aug 03, 2007. Female patient, 14 years of age, was diagnosed with nasopharyngeal cancer stage iii and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: chronic sinusitis, conductive deafness, dental caries, osteonecrosis, otorrhoea, trismus. LEUCOVORIN dosage: 25 MG/M2 PER_CYCLE. During the same period patient was treated with METHOTREXATE, CISPLATIN, FLUOROURACIL. Patient recovered.

Physician from UNITED STATES reported LEUCOVORIN problem on Aug 03, 2007. Female patient, child 10 years of age, was diagnosed with nasopharyngeal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: chronic sinusitis, conductive deafness, dry mouth, effusion, eustachian tube dysfunction, local swelling, myopia, nodule. LEUCOVORIN dosage: 25 MG/M2 PER_CYCLE. During the same period patient was treated with METHOTREXATE, CISPLATIN, FLUOROURACIL. Patient was hospitalized and became disabled. Patient recovered.

LEUCOVORIN problem was reported by a Physician from UNITED STATES on Aug 03, 2007. Male patient, 14 years of age, was diagnosed with nasopharyngeal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: blood testosterone decreased, conductive deafness, deafness neurosensory, dental caries, disease recurrence, dry mouth, gingival hyperplasia, growth hormone deficiency. LEUCOVORIN dosage: 25 MG/M2 PER_CYCLE. During the same period patient was treated with METHOTREXATE, CISPLATIN, FLUOROURACIL. Patient was hospitalized and became disabled. Patient recovered.

Health Professional from JAPAN reported LEUCOVORIN problem on Aug 17, 2007. Male patient, 67 years of age, weighting 143.3 lb, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: anorexia, gastric ulcer. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.

LEUCOVORIN problem was reported by a Health Professional from JAPAN on Aug 23, 2007. Male patient, weighting 114.6 lb, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: blood potassium increased, leukopenia, neutropenia, thrombocytopenia. LEUCOVORIN dosage: 150MG/BODY=100MG/M2 D1+2. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Health Professional from UNITED STATES reported LEUCOVORIN problem on Aug 21, 2007. Male patient, 64 years of age, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, eye injury, eye penetration, fall, pneumonia, pulmonary fibrosis, respiratory failure. LEUCOVORIN dosage: 800 MG INTRAVENOUSLY. Patient was hospitalized. Patient died on 07/15/2007.

LEUCOVORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 21, 2007. Male patient, 57 years of age, was diagnosed with colorectal cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea, gastrointestinal haemorrhage, metabolic acidosis, septic shock, upper gastrointestinal haemorrhage. LEUCOVORIN dosage: 400 MG/M2 INTRAVENOUSLY 1/2 W. During the same period patient was treated with REFER TO ATTACHED CIOMS. Patient was hospitalized. Patient died on 10/03/2005.

Health Professional from UNITED STATES reported LEUCOVORIN problem on May 25, 2007. Male patient, 50 years of age, was diagnosed with colorectal cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia. LEUCOVORIN dosage: 832 MG FORTNIGHTLY IV. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.

LEUCOVORIN problem was reported by a Health Professional from JAPAN on Aug 22, 2007. Male patient, weighting 136.7 lb, was diagnosed with rectal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: dyspnoea, loss of consciousness. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Physician from ISRAEL reported LEUCOVORIN problem on Sept 03, 2007. Male patient was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: cryptogenic cirrhosis. LEUCOVORIN dosage: 388 MG. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient died on 05/03/2007.

LEUCOVORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 28, 2007. Male patient, 82 years of age, was diagnosed with colorectal cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: anaemia, asthenia, dehydration, neutropenic sepsis, paraneoplastic syndrome, stomatitis. LEUCOVORIN dosage: 800MG/IV/EVERY 2 WEEKS. Patient was hospitalized. Patient died on 07/31/2007.

Physician from UNITED STATES reported LEUCOVORIN problem on Sept 10, 2007. Female patient was diagnosed with colorectal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: anaemia, chronic obstructive pulmonary disease, sepsis. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, BEVACIZUMAB, OXALIPLATIN. Patient was hospitalized. Patient recovered.

LEUCOVORIN problem was reported by a Health Professional from UNITED STATES on Sept 06, 2007. Female patient was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, BEVACIZUMAB, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from UNITED STATES reported LEUCOVORIN problem on Sept 05, 2007. Female patient, 77 years of age, was diagnosed with colorectal cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, asthenia, febrile neutropenia, pulmonary embolism, respiratory failure, sepsis, stomatitis. LEUCOVORIN dosage: 400MG/M2; IV. During the same period patient was treated with OXALIPLATIN, BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, REFER TO CIOMSM, REFER TO ATTACHED CIOMSM, ACTONEL, ACYCLOVIR. Patient was hospitalized. Patient died on 07/28/2007.

LEUCOVORIN problem was reported by a Health Professional from PORTUGAL on Sept 20, 2007. Female patient, weighting 130.1 lb, was diagnosed with neurological symptom and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction, electrocardiogram abnormal, metastases to lung. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient died on 09/15/2007.

Health Professional from UNITED STATES reported LEUCOVORIN problem on Sept 13, 2007. Female patient, 55 years of age, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: blood culture positive, escherichia infection, hydronephrosis, nausea, nephrolithiasis, neutrophil count decreased, perinephric collection. LEUCOVORIN dosage: 744MG/M2/IV. Patient was hospitalized. Patient recovered.

LEUCOVORIN problem was reported by a Health Professional from JAPAN on Sept 12, 2007. Male patient, weighting 136.7 lb, was diagnosed with rectal cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: dyspnoea, loss of consciousness. LEUCOVORIN dosage: unknown. During the same period patient was treated with OXALIPLATIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.

Health Professional from PORTUGAL reported LEUCOVORIN problem on Sept 20, 2007. Female patient, weighting 130.1 lb, was diagnosed with neurological symptom and was treated with LEUCOVORIN. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient died on 09/15/2007.

LEUCOVORIN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 17, 2007. Male patient, 63 years of age, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: agitation, anxiety, haemolytic anaemia, pain, recurrent cancer. LEUCOVORIN dosage: unknown. During the same period patient was treated with OXALIPLATIN, ELOXATIN, FLUOROURACIL, XELODA, OLANZAPINE. Patient was hospitalized. Patient recovered.

Health Professional from UNITED STATES reported LEUCOVORIN problem on Sept 18, 2007. Male patient, 82 years of age, was diagnosed with colorectal cancer metastatic and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: anaemia, asthenia, dehydration, neutropenia, paraneoplastic syndrome, sepsis, stomatitis. LEUCOVORIN dosage: 800MG/IV/EVERY 2 WEEKS. Patient was hospitalized. Patient died on 07/31/2007.

LEUCOVORIN problem was reported by a Health Professional from JAPAN on Sept 19, 2007. Female patient, weighting 114.6 lb, was diagnosed with rectal cancer, hypersensitivity and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: disseminated intravascular coagulation, haemoglobin decreased, leukopenia, neutropenia, thrombocytopenia. LEUCOVORIN dosage: 154 MG INFUSION ON D1+2. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, OXALIPLATIN. Patient was hospitalized. Patient recovered.

Health Professional from JAPAN reported LEUCOVORIN problem on Sept 21, 2007. Male patient, weighting 92.59 lb, was diagnosed with colon cancer and was treated with LEUCOVORIN. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage. LEUCOVORIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, OXALIPLATIN. Patient recovered.

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