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Heart Racing (7)
Locla Injection Finger (5)
SWOLLEN UPPER LIP (3)
Uncontrollable Shaking (2)
Acute Myotonia (1)
Chest Pain (1)
Cramps (1)
>>View All User Submitted Lignocaine Side Effects

Lignocaine Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 37 

Aphonia (7762750-9)
on Sep 12, 2011 Female from INDIA , 30 years of age, weighting 154.3 lb, was treated with Lignocaine With Epinephrine. Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: aphonia. Lignocaine With Epinephrine dosage: N/A.
Associated medications used:
  • Diazepam (10 Mg)
  • Bupivacaine Hcl


Disorientation, Tachycardia (6960207-6)
Patient was taking Lignocaine With Adrenaline. Patient felt the following Lignocaine side effects: disorientation, tachycardia on Mar 05, 2010 from UNITED KINGDOM Additional patient health information: Female , 50 years of age, was diagnosed with
  • migraine
  • dental care
and. Lignocaine With Adrenaline dosage: N/A.
Multiple prescriptions taken:
  • Citanest With Octapressin
  • Rizatriptan Benzoate
  • Scandonest Plain
  • Septanest
  • Pizotifen
  • Sertraline Hydrochloride


Delirium, Paralysis (6435775-3)
Adverse event was reported on Nov 02, 2009 by a Female taking Lignocaine (Dosage: Single Dose) . Location: NEW ZEALAND , 49 years of age, After Lignocaine was administered, patient encountered several Lignocaine side effects: delirium, paralysis.
Multiple concurrent drugs taken:
  • Lorazepam
Patient was hospitalized.

Anaphylactic Reaction (6427894-2)
on Nov 02, 2009 Male from NEW ZEALAND , 56 years of age, was treated with Lignocaine. Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: anaphylactic reaction. Lignocaine dosage: N/A.
Associated medications used:
  • Simvastatin
  • Omeprazole
  • Felodipine
  • Flucloxacillin



Dyspnoea, Heart Rate Increased, Loss Of Consciousness (6299283-5)
on Aug 03, 2009 Female from AUSTRALIA , 80 years of age, was treated with Lignocaine. Patient felt the following Lignocaine side effects: dyspnoea, heart rate increased, loss of consciousness. Lignocaine dosage: N/A.
Multiple prescriptions taken:
  • Fentanyl
  • Hyalase
  • Midazolam Hcl


Anxiety, Chills, Disorientation, Gait Disturbance, Hearing Impaired, Injection Site Pain, Insomnia, Speech Disorder (6294342-5)
Patient was taking Lignocaine. After Lignocaine was administered, patient encountered several Lignocaine side effects: anxiety, chills, disorientation, gait disturbance, hearing impaired, injection site pain, insomnia, speech disorder on Feb 05, 2009 from AUSTRALIA Additional patient health information: Patient , 55 years of age, . Lignocaine dosage: N/A.
Multiple concurrent drugs taken:
  • Lyrica
  • Celestone


Bradycardia, Hypotension, Syncope Vasovagal (5714933-7)
Adverse event was reported on Apr 18, 2008 by a Male taking Lignocaine (Dosage: N/A) was diagnosed with
  • local anaesthesia
and. Location: UNITED KINGDOM , 39 years of age, Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: bradycardia, hypotension, syncope vasovagal.
Associated medications used:
  • Chirocaine (107048w01)
  • Cymbalta (30 Mg)
  • Propranolol (40 Mg)


Dyspnoea, Rash, Wheezing (5557895-8)
on Dec 11, 2007 Female from UNITED KINGDOM , 52 years of age, was diagnosed with
  • bronchoscopy
and was treated with Lignocaine. Patient felt the following Lignocaine side effects: dyspnoea, rash, wheezing. Lignocaine dosage: N/A.

Emotional Distress, Hypoaesthesia Oral, Paraesthesia Oral, Tearfulness (5523622-3)
on Nov 09, 2007 Female from UNITED KINGDOM , 45 years of age, was diagnosed with
  • anaesthesia
and was treated with Lignocaine. After Lignocaine was administered, patient encountered several Lignocaine side effects: emotional distress, hypoaesthesia oral, paraesthesia oral, tearfulness. Lignocaine dosage: N/A.

Angioedema, Convulsion, Renal Failure Acute, Swollen Tongue (5521125-3)
Patient was taking Lignocaine. Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: angioedema, convulsion, renal failure acute, swollen tongue on Nov 13, 2007 from UNITED KINGDOM Additional patient health information: Male , 70 years of age, . Lignocaine dosage: N/A.
Associated medications used:
  • Lisinopril
Patient was hospitalized.

Completed Suicide, Overdose (5451345-8)
Adverse event was reported on Sep 10, 2007 by a Female taking Lignocaine (Dosage: N/A) . Location: UNITED KINGDOM , 31 years of age, Patient felt the following Lignocaine side effects: completed suicide, overdose.

Intentional Overdose (5447774-9)
on Sep 05, 2007 Male from UNITED KINGDOM , 58 years of age, was treated with Lignocaine. After Lignocaine was administered, patient encountered several Lignocaine side effects: intentional overdose. Lignocaine dosage: N/A.

Intentional Overdose (5447767-1)
on Sep 05, 2007 Female from UNITED KINGDOM , 20 years of age, was treated with Lignocaine. Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: intentional overdose. Lignocaine dosage: N/A.
Associated medications used:
  • Amitriptyline Hcl
  • Mefenamic Acid


Intentional Overdose (5443079-0)
Patient was taking Lignocaine. Patient felt the following Lignocaine side effects: intentional overdose on Aug 28, 2007 from ITALY Additional patient health information: Male , 58 years of age, . Lignocaine dosage: N/A.

Metabolic Acidosis, Overdose, Tachycardia (5419782-5)
Adverse event was reported on Aug 14, 2007 by a Male taking Lignocaine (Dosage: N/A) . Location: UNITED KINGDOM , 19 years of age, After Lignocaine was administered, patient encountered several Lignocaine side effects: metabolic acidosis, overdose, tachycardia.
Multiple concurrent drugs taken:
  • Ibuprofen Tablets
  • Cyclobenzaprine Hcl
  • Phenylpropanolamine
  • Chlorpheniramine Tab
  • Phenytoin


Metabolic Acidosis, Overdose, Tachycardia (5406290-0)
on Aug 01, 2007 Male from UNITED KINGDOM , 19 years of age, was treated with Lignocaine. Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: metabolic acidosis, overdose, tachycardia. Lignocaine dosage: N/A.
Associated medications used:
  • Ibuprofen
  • Cyclobenzaprine Hcl
  • Phenylpropanolamine
  • Chlorpheniramine Maleate
  • Phenytoin


Diplegia, Sensory Loss (5347809-8)
on May 23, 2007 Female from UNITED KINGDOM , 36 years of age, was diagnosed with
  • skin laceration
  • tooth disorder
and was treated with Lignocaine. Patient felt the following Lignocaine side effects: diplegia, sensory loss. Lignocaine dosage: N/A.

Chest Discomfort, Feeling Hot, Pruritus (5149730-7)
Patient was taking Lignocaine. After Lignocaine was administered, patient encountered several Lignocaine side effects: chest discomfort, feeling hot, pruritus on Nov 01, 2006 from UNITED KINGDOM Additional patient health information: Female , 30 years of age, . Lignocaine dosage: N/A.
Multiple concurrent drugs taken:
  • Benzathine Penicillin G (2.4 Million International Units)
  • Beclomethasone Dipropionate
  • Salbutamol


Bronchospasm, Circulatory Collapse (5125831-4)
Adverse event was reported on Oct 09, 2006 by a Female taking Lignocaine (Dosage: N/A) . Location: UNITED KINGDOM , 39 years of age, weighting 154.3 lb, Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: bronchospasm, circulatory collapse.
Associated medications used:
  • Propofol
  • Cefuroxime
  • Fentanyl
  • Rocuronium
  • Levothyroxine Sodium
  • Inhaler
  • Oral Contraceptive
Patient was hospitalized.

Colon Gangrene, Grand Mal Convulsion, Intestinal Gangrene, Intestinal Infarction, Myocardial Infarction (5086788-8)
on Aug 01, 2006 Male from UNITED KINGDOM , 72 years of age, was treated with Lignocaine. Patient felt the following Lignocaine side effects: colon gangrene, grand mal convulsion, intestinal gangrene, intestinal infarction, myocardial infarction. Lignocaine dosage: 2% In Error Instead Of 1%.

Colon Gangrene, Grand Mal Convulsion, Myocardial Infarction (5072340-7)
on Aug 01, 2006 Male from UNITED KINGDOM , 72 years of age, was treated with Lignocaine. After Lignocaine was administered, patient encountered several Lignocaine side effects: colon gangrene, grand mal convulsion, myocardial infarction. Lignocaine dosage: 2% In Error Instead Of 1%.

Diplopia, Muscle Atrophy, Muscle Fibrosis, Muscle Injury, Muscle Tightness, Strabismus, Vision Blurred (5033139-0)
Patient was taking Lignocaine. Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: diplopia, muscle atrophy, muscle fibrosis, muscle injury, muscle tightness, strabismus, vision blurred on Jun 12, 2006 from LEBANON Additional patient health information: Male , 72 years of age, was diagnosed with
  • local anaesthesia
and. Lignocaine dosage: N/A.
Associated medications used:
  • Bupivacaine
  • Hyaluronidase


Conjunctival Oedema, Exophthalmos, Eye Inflammation, Eye Movement Disorder, Eye Oedema, Iatrogenic Injury, Muscle Swelling, Ocular Discomfort, Optic Nerve Disorder (4922054-6)
Adverse event was reported on Feb 13, 2006 by a Female taking Lignocaine (Dosage: Injected Into Sub-tenon's Space.) was diagnosed with
  • local anaesthesia
and. Location: UNITED KINGDOM , 74 years of age, Patient felt the following Lignocaine side effects: conjunctival oedema, exophthalmos, eye inflammation, eye movement disorder, eye oedema, iatrogenic injury, muscle swelling, ocular discomfort, optic nerve disorder.
Multiple prescriptions taken:
  • Bupivacaine (Injected Into Sub-tenon's Space.)
  • Hyaluronidase (Injected Into Sub-tenon's Space.)
  • Proxymetacaine
  • Povidone Iodine (Instilled Into Conjunctival Sac.)
  • Chloramphenicol
  • Prednisolone


Conjunctival Oedema, Exophthalmos, Eye Inflammation, Eye Pain, Intraocular Pressure Increased, Intraocular Pressure Test, Soft Tissue Injury (4921580-3)
on Feb 13, 2006 Female from UNITED KINGDOM , 74 years of age, was diagnosed with
  • local anaesthesia
and was treated with Lignocaine. After Lignocaine was administered, patient encountered several Lignocaine side effects: conjunctival oedema, exophthalmos, eye inflammation, eye pain, intraocular pressure increased, intraocular pressure test, soft tissue injury. Lignocaine dosage: Injected Into Sub-tenon's Space.
Multiple concurrent drugs taken:
  • Bupivacaine (Injected Into Sub-tenon's Space)
  • Hyaluronidase (Injected Into Sub-tenon's Space)
  • Proxymetacaine
  • Povidone Iodine (Instilled Into Conjunctival Sac)
  • Povidone Iodine (Used To Clean Skin Before Surgery.)
  • Cefuroxime
  • Cefuroxime (Intracamerally)
  • Chloramphenicol


Anaphylactic Reaction, Asthenia, Burning Sensation, Diarrhoea, Dyspnoea (4893536-0)
on Jan 20, 2006 Female from AUSTRALIA , weighting 231.9 lb, was diagnosed with
  • infiltration anaesthesia
  • nasopharyngitis
and was treated with Lignocaine Hydrochloride And Adrenaline. Directly after, patient experienced the unwanted or unexpected Lignocaine side effects: anaphylactic reaction, asthenia, burning sensation, diarrhoea, dyspnoea. Lignocaine Hydrochloride And Adrenaline dosage: N/A.
Associated medications used:
  • Benadryl Chesty Forte
Patient was hospitalized.

Showing 1-25 of 37 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Lignocaine Information

More About Lignocaine

Side Effects reported to FDA: 37. View Lignocaine Adverse Reports

Lignocaine safety alerts: No

Reported deaths: 8

Reported hospitalizations: 11

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