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Macrobid Side Effects

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Common Macrobid Side Effects


The most commonly reported Macrobid side effects (click to view or check a box to report):

Dyspnoea (46)
Nausea (36)
Headache (32)
Pyrexia (31)
Pain (30)
Chills (27)
Asthenia (24)
Malaise (22)
Cough (17)
Chest Pain (17)
Fatigue (17)
Dizziness (17)
Vomiting (16)
Hypoaesthesia (13)
Rash (13)
Arthralgia (13)
Paraesthesia (11)
Abdominal Pain Upper (11)
Abdominal Pain (10)
Erythema (10)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Macrobid Side Effects Reported to FDA



Macrobid Side Effect Report#9998301
Cerebrovascular Accident, Dysphonia
This is a report of a 56-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: cystitis, who was treated with Macrobid (dosage: NA, start time:
Jan 28, 2010), combined with: NA. and developed a serious reaction and side effect(s): Cerebrovascular Accident, Dysphonia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Macrobid treatment in female patients, resulting in Cerebrovascular Accident side effect.
Macrobid Side Effect Report#9918717
Anaphylactic Reaction, Flushing, Dysphagia, Swollen Tongue, Urticaria, Dyspnoea, Nausea, Vomiting, Headache
This report suggests a potential Macrobid Anaphylactic Reaction side effect(s) that can have serious consequences. A 53-year-old female patient (weight: NA) from CA was diagnosed with the following symptoms/conditions: urinary tract infection,dysuria and used Macrobid (dosage: NA) starting
Jan 30, 2014. After starting Macrobid the patient began experiencing various side effects, including: Anaphylactic Reaction, Flushing, Dysphagia, Swollen Tongue, Urticaria, Dyspnoea, Nausea, Vomiting, HeadacheAdditional drugs used concurrently: NA.The patient was hospitalized. Although Macrobid demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Anaphylactic Reaction, may still occur.
Macrobid Side Effect Report#9845098
Dizziness, Dyspnoea, Pain, Joint Stiffness, Arthralgia, Hypoaesthesia, Arthropathy, Headache
This Dizziness problem was reported by a consumer or non-health professional from US. A 19-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 18, 2014 this consumer started treatment with Macrobid (dosage: NA). The following drugs were being taken at the same time: NA. When using Macrobid, the patient experienced the following unwanted symptoms/side effects: Dizziness, Dyspnoea, Pain, Joint Stiffness, Arthralgia, Hypoaesthesia, Arthropathy, HeadacheAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Dizziness, may become evident only after a product is in use by the general population.
Macrobid Side Effect Report#9820696
Rosacea, Groin Pain, Musculoskeletal Pain
This Rosacea side effect was reported by a consumer or non-health professional from US. A 44-year-old female patient (weight:NA) experienced the following symptoms/conditions: urinary tract infection.The patient was prescribed Macrobid (drug dosage: By Mouth), which was initiated on
Sep 04, 2013. Concurrently used drugs:
  • Multi-vitamin
  • Calcium
  • Vit D
.After starting to take Macrobid the consumer reported adverse symptoms, such as: Rosacea, Groin Pain, Musculoskeletal PainThese side effects may potentially be related to Macrobid.
Macrobid Side Effect Report#9784747
Fibromyalgia, Vulvovaginal Pain, Nerve Injury, Asthma
This is a report of a 30-year-old female patient (weight: NA) from CA, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Macrobid (dosage: NA, start time:
Dec 11, 2013), combined with: NA. and developed a serious reaction and side effect(s): Fibromyalgia, Vulvovaginal Pain, Nerve Injury, Asthma after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Macrobid treatment in female patients, resulting in Fibromyalgia side effect.
Macrobid Side Effect Report#9781191
Musculoskeletal Pain, Axillary Pain, Breast Pain
This report suggests a potential Macrobid Musculoskeletal Pain side effect(s) that can have serious consequences. A 70-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: urinary tract infection and used Macrobid (dosage: 1 Pil Twice Daily, Twice Daily, Taken By Mouth) starting
Oct 10, 2013. After starting Macrobid the patient began experiencing various side effects, including: Musculoskeletal Pain, Axillary Pain, Breast PainAdditional drugs used concurrently: NA.The patient was hospitalized and became disabled. Although Macrobid demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Musculoskeletal Pain, may still occur.
Macrobid Side Effect Report#9765250
Nerve Injury, Fibromyalgia, Neuralgia, Fungal Infection, Infection, Fatigue, Alopecia, Arthralgia, Headache
This Nerve Injury problem was reported by a consumer or non-health professional from CA. A 29-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection,prophylaxis urinary tract infection. On NS this consumer started treatment with Macrobid (dosage: NA). The following drugs were being taken at the same time: NA. When using Macrobid, the patient experienced the following unwanted symptoms/side effects: Nerve Injury, Fibromyalgia, Neuralgia, Fungal Infection, Infection, Fatigue, Alopecia, Arthralgia, HeadacheAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Nerve Injury, may become evident only after a product is in use by the general population.
Macrobid Side Effect Report#9701025
Asthma
This Asthma side effect was reported by a consumer or non-health professional from US. A patient (weight:NA) experienced the following symptoms/conditions: urinary tract infection.The patient was prescribed Macrobid (drug dosage: NA), which was initiated on
May 29, 2012. Concurrently used drugs: NA..After starting to take Macrobid the consumer reported adverse symptoms, such as: AsthmaThese side effects may potentially be related to Macrobid. The patient was hospitalized and became disabled.
Macrobid Side Effect Report#9697454
Rash, Feeling Hot
This is a report of a 22-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Macrobid (dosage: 1 Twice Daily Taken By Mouth, start time:
Nov 09, 2013), combined with: NA. and developed a serious reaction and side effect(s): Rash, Feeling Hot after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Macrobid treatment in female patients, resulting in Rash side effect.
Macrobid Side Effect Report#9695947
Tremor, Pyrexia, Chills, Pain, Nausea, Vomiting, Jaundice, Aphagia
This report suggests a potential Macrobid Tremor side effect(s) that can have serious consequences. A 58-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: urinary tract infection and used Macrobid (dosage: 100 Mg 1 Pill Every 12 Hours Orally) starting
Oct 31, 2013. After starting Macrobid the patient began experiencing various side effects, including: Tremor, Pyrexia, Chills, Pain, Nausea, Vomiting, Jaundice, AphagiaAdditional drugs used concurrently:
  • Multaq
  • Atenolol
  • Hctz
  • Aspirin
  • Fish Oil
  • Multivitamin
  • Vitamin D/calcium
Although Macrobid demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Tremor, may still occur.
Macrobid Side Effect Report#9586269
Blood Pressure Decreased, Pneumonitis
This Blood Pressure Decreased problem was reported by a pharmacist from CA. A 93-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Macrobid (nitrofurantoin) (dosage: NA). The following drugs were being taken at the same time:
  • Rabeprazole
  • Hydromorphone
  • Digoxin
  • Furosemide
  • Levothyroxine
  • Calcium Citrate
  • Colecalciferol
  • Zopiclone
When using Macrobid (nitrofurantoin), the patient experienced the following unwanted symptoms/side effects: Blood Pressure Decreased, PneumonitisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Blood Pressure Decreased, may become evident only after a product is in use by the general population.
Macrobid Side Effect Report#9563851
Oropharyngeal Pain, Cough, Headache
This Oropharyngeal Pain side effect was reported by a consumer or non-health professional from US. A 33-year-old female patient (weight:NA) experienced the following symptoms/conditions: urinary tract infection.The patient was prescribed Macrobid (drug dosage: 1 Pill; Twice Daily), which was initiated on NS. Concurrently used drugs: NA..After starting to take Macrobid the consumer reported adverse symptoms, such as: Oropharyngeal Pain, Cough, HeadacheThese side effects may potentially be related to Macrobid.
Macrobid Side Effect Report#9511353
Interstitial Lung Disease
This is a report of a 47-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Macrobid (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Interstitial Lung Disease after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Macrobid treatment in female patients, resulting in Interstitial Lung Disease side effect.
Macrobid Side Effect Report#9507647
Urticaria, Swelling, Lymphadenopathy, Chills, Night Sweats, Dyspnoea, Heart Rate Increased, White Blood Cell Count Increased, Pyrexia
This report suggests a potential Macrobid Urticaria side effect(s) that can have serious consequences. A 57-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: urinary tract infection and used Macrobid (dosage: NA) starting NS. After starting Macrobid the patient began experiencing various side effects, including: Urticaria, Swelling, Lymphadenopathy, Chills, Night Sweats, Dyspnoea, Heart Rate Increased, White Blood Cell Count Increased, PyrexiaAdditional drugs used concurrently:
  • Simvastin
  • Activella
  • Niacin
  • Baby Aspirin
  • Vitamin
The patient was hospitalized. Although Macrobid demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Urticaria, may still occur.
Macrobid Side Effect Report#9490590
Syncope, Hepatitis Acute, Mixed Liver Injury, Hepatocellular Injury
This Syncope problem was reported by a health professional from CA. A 94-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection. On 2011 this consumer started treatment with Macrobid (dosage: NA). The following drugs were being taken at the same time:
  • Mavik
  • Polyethylene Glycol
  • Amlodipine
  • Cyanocobalamin
  • Atorvastatin
  • Clopidogrel
  • Levothyroxine
  • Lorazepam
When using Macrobid, the patient experienced the following unwanted symptoms/side effects: Syncope, Hepatitis Acute, Mixed Liver Injury, Hepatocellular InjuryThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Syncope, may become evident only after a product is in use by the general population.
Macrobid Side Effect Report#9490561
Palpitations, Rash, Hypoaesthesia, Dyspnoea, Chest Pain
This Palpitations side effect was reported by a consumer or non-health professional from CA. A 44-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Macrobid (drug dosage: NA), which was initiated on
Nov 03, 2012. Concurrently used drugs: NA..After starting to take Macrobid the consumer reported adverse symptoms, such as: Palpitations, Rash, Hypoaesthesia, Dyspnoea, Chest PainThese side effects may potentially be related to Macrobid.
Macrobid Side Effect Report#9490512
Hyperhidrosis, Pulmonary Fibrosis, Nausea, Eosinophilia
This is a report of a 53-year-old female patient (weight: NA) from CA, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Macrobid (dosage: NA, start time:
Aug 14, 2012), combined with: NA. and developed a serious reaction and side effect(s): Hyperhidrosis, Pulmonary Fibrosis, Nausea, Eosinophilia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Macrobid treatment in female patients, resulting in Hyperhidrosis side effect. The patient was hospitalized.
Macrobid Side Effect Report#9490494
Blood Pressure Decreased, Pneumonitis
This report suggests a potential Macrobid Blood Pressure Decreased side effect(s) that can have serious consequences. A 93-year-old female patient (weight: NA) from CA was diagnosed with the following symptoms/conditions: urinary tract infection and used Macrobid (dosage: NA) starting
Feb 06, 2013. After starting Macrobid the patient began experiencing various side effects, including: Blood Pressure Decreased, PneumonitisAdditional drugs used concurrently:
  • Rabeprazole
  • Hydromorphone
  • Digoxin
  • Furosemide
  • Levothyroxine
  • Calcium Citrate
  • Colecalciferol
  • Zopiclone
The patient was hospitalized. Although Macrobid demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Blood Pressure Decreased, may still occur.
Macrobid Side Effect Report#9490480
Coma, Confusional State, Hallucination, Fall, Viith Nerve Paralysis
This Coma problem was reported by a health professional from CA. A 93-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection,pneumonia. On 2012 this consumer started treatment with Macrobid (dosage: NA). The following drugs were being taken at the same time:
  • Moxifloxacin Hydrochloride
When using Macrobid, the patient experienced the following unwanted symptoms/side effects: Coma, Confusional State, Hallucination, Fall, Viith Nerve ParalysisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Coma, may become evident only after a product is in use by the general population.
Macrobid Side Effect Report#9490455
Cerebrovascular Accident, Toxicity To Various Agents, Pancytopenia
This Cerebrovascular Accident side effect was reported by a health professional from CA. A 94-year-old female patient (weight:NA) experienced the following symptoms/conditions: prophylaxis urinary tract infection,cerebrovascular accident prophylaxis.The patient was prescribed Macrobid (drug dosage: NA), which was initiated on
Sep 04, 2012. Concurrently used drugs:
  • Plavix
  • Systane Lubricant
  • Acebutolol Hydrochloride
  • Venlafaxine Hydrochloride
  • Seroquel
  • Ativan
  • Lumigan
  • Xalatan
.After starting to take Macrobid the consumer reported adverse symptoms, such as: Cerebrovascular Accident, Toxicity To Various Agents, PancytopeniaThese side effects may potentially be related to Macrobid. The patient was hospitalized.
Macrobid Side Effect Report#9490440
Renal Failure Acute, Hepatitis Acute, Depressed Level Of Consciousness
This is a report of a 68-year-old female patient (weight: NA) from CA, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Macrobid (dosage: NA, start time: 201207), combined with:
  • Citalopram
  • Haloperidol
  • Lorazepam
  • Hypromellose
  • Clopidogrel
  • Entrophen
  • Trazodone
  • Acetaminophen
and developed a serious reaction and side effect(s): Renal Failure Acute, Hepatitis Acute, Depressed Level Of Consciousness after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Macrobid treatment in female patients, resulting in Renal Failure Acute side effect. The patient was hospitalized.
Macrobid Side Effect Report#9490170
Asthma, Syncope, Swelling Face, Nausea, Diarrhoea, Abdominal Pain, Dizziness, Pruritus
This report suggests a potential Macrobid Asthma side effect(s) that can have serious consequences. A 45-year-old female patient (weight: NA) from CA was diagnosed with the following symptoms/conditions: cystitis and used Macrobid (dosage: NA) starting
Jul 27, 2012. After starting Macrobid the patient began experiencing various side effects, including: Asthma, Syncope, Swelling Face, Nausea, Diarrhoea, Abdominal Pain, Dizziness, PruritusAdditional drugs used concurrently: NA.The patient was hospitalized. Although Macrobid demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Asthma, may still occur.
Macrobid Side Effect Report#9486650
Hypoaesthesia, Paraesthesia, Blood Potassium Decreased, Neuropathy Peripheral, Toxic Neuropathy, Gait Disturbance, Pain
This Hypoaesthesia problem was reported by a consumer or non-health professional from US. A 65-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Macrobid (dosage: NA). The following drugs were being taken at the same time:
  • Gabapentin
  • Lipitor
  • Symbicort
  • Dicyclomine
  • Atenolol-chloralidrm
  • Aspirin
  • Klor-con
When using Macrobid, the patient experienced the following unwanted symptoms/side effects: Hypoaesthesia, Paraesthesia, Blood Potassium Decreased, Neuropathy Peripheral, Toxic Neuropathy, Gait Disturbance, PainAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hypoaesthesia, may become evident only after a product is in use by the general population.
Macrobid Side Effect Report#9466052
Neuropathy Peripheral
This Neuropathy Peripheral side effect was reported by a consumer or non-health professional from US. A 62-year-old female patient (weight:NA) experienced the following symptoms/conditions: bronchitis,sinusitis.The patient was prescribed Macrobid (drug dosage: Three Times Daily Taken By Mouth??april Or May Of 2008), which was initiated on NS. Concurrently used drugs: NA..After starting to take Macrobid the consumer reported adverse symptoms, such as: Neuropathy PeripheralThese side effects may potentially be related to Macrobid.
Macrobid Side Effect Report#9456233
Malaise, No Therapeutic Response, Asthenia, Dyspnoea, Disturbance In Attention, Tremor, Tremor, Confusional State, Hypersomnia
This is a report of a 70-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: urinary tract infection bacterial, who was treated with Macrobid (dosage: NA, start time:
Jul 30, 2013), combined with: NA. and developed a serious reaction and side effect(s): Malaise, No Therapeutic Response, Asthenia, Dyspnoea, Disturbance In Attention, Tremor, Tremor, Confusional State, Hypersomnia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Macrobid treatment in female patients, resulting in Malaise side effect.


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The appearance of Macrobid on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

What are common Macrobid Side Effects for Women?

Women Side EffectsReports
Dyspnoea 43
Nausea 34
Headache 32
Pain 29
Pyrexia 28
Chills 24
Asthenia 22
Malaise 22
Dizziness 17
Chest Pain 16

What are common Macrobid Side Effects for Men?

Men Side EffectsReports
Chills 3
Dyspnoea 3
Pyrexia 3
Asthenia 2
Coma 2
Confusional State 2
Hallucination 2
Joint Swelling 2
Nausea 2
Viith Nerve Paralysis 2

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Macrobid reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    How Effective is Macrobid for You?

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    Macrobid Safety Alerts, Active Ingredients, Usage Information

    NDC52427-285
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameMacrobid
    NameNitrofurantoin Monohydrate/Macrocrystalline
    Dosage FormCAPSULE
    RouteORAL
    On market since20110531
    LabelerAlmatica Pharma Inc.
    Active Ingredient(s)NITROFURANTOIN; NITROFURANTOIN MONOHYDRATE
    Strength(s)25; 75
    Unit(s)mg/1; mg/1
    Pharma ClassNitrofuran Antibacterial [EPC],Nitrofurans [Chemical/Ingredient],Nitrofuran Antibacterial [EPC],Nitr

    Macrobid Dosage, Warnings, Usage.

    Side Effects reported to FDA: 256

    Macrobid safety alerts: No

    Reported deaths: 12

    Reported hospitalizations: 124

    Latest Macrobid clinical trials