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Constipation (18)
Low Blood Pressure (16)
Depression (8)
Chronic Diarrhea (7)
Drowsiness (6)
Poor Balance (6)
Skin Rash (5)
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Madopar Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 62 

Fall, Loss Of Consciousness (7974043-5)
on Dec 05, 2011 Male from JAPAN , 82 years of age, was diagnosed with
  • parkinson's disease
and was treated with Madopar. Directly after, patient experienced the unwanted or unexpected Madopar side effects: fall, loss of consciousness. Madopar dosage: 3iuax Per Day.
Associated medications used:
  • Symmetrel (100mg Per Day)
  • Requip (1.5mg Per Day)
  • Radicut
Patient was hospitalized.

Sopor, Pleurisy, Anuria (7966940-1)
Patient was taking Madopar. Patient felt the following Madopar side effects: sopor, pleurisy, anuria on Dec 06, 2011 from ITALY Additional patient health information: Male , 77 years of age, . Madopar dosage: N/A.
Multiple prescriptions taken:
  • Lyrica (75 Mg, Single)
  • Oxycontin (80 Mg, Single)
Patient was hospitalized.

Cold Sweat, Orthostatic Hypotension, Pallor, Syncope (7893543-X)
Adverse event was reported on Nov 01, 2011 by a Male taking Madopar (Dosage: N/A) was diagnosed with
  • parkinson's disease
and. Location: UNITED KINGDOM , 83 years of age, After Madopar was administered, patient encountered several Madopar side effects: cold sweat, orthostatic hypotension, pallor, syncope.
Multiple concurrent drugs taken:
  • Sinemet
  • Pregabalin
  • Nicorandil
Patient was hospitalized.

Overdose, Extrapyramidal Disorder, Disorientation, Fatigue (7846662-8)
on Oct 18, 2011 Male from GERMANY , 75 years of age, weighting 165.3 lb, was treated with Madopar. Directly after, patient experienced the unwanted or unexpected Madopar side effects: overdose, extrapyramidal disorder, disorientation, fatigue. Madopar dosage: 125 Mg, Daily.
Associated medications used:
  • Exelon (2 Df (4.6 Mg/24 Hr))
  • Seroquel (25 Mg, Daily)
  • Exelon (4.6 Mg/24 Hr)
  • Exelon (9.5 Mg/24 Hr)
  • Citalopram Hydrobromide (20 Mg, Daily)



Hypoglycaemia, Altered State Of Consciousness (7808910-X)
on Oct 04, 2011 Male from JAPAN , 58 years of age, weighting 95.46 lb, was diagnosed with
  • parkinson's disease
  • bronchopulmonary aspergillosis
and was treated with Madopar. Patient felt the following Madopar side effects: hypoglycaemia, altered state of consciousness. Madopar dosage: Unk.
Multiple prescriptions taken:
  • Vfend (6 Mg/kg, 2x/day)
  • Bladderon
  • Dops (200 Mg, 3x/day)
  • Vfend (4 Mg/kg, 2x/day)
  • Selegiline Hcl (2.5 Mg, 2x/day)
  • Comtan (100 Mg, 4x/day)
  • Requip


Depressed Level Of Consciousness (7802605-4)
Patient was taking Madopar. After Madopar was administered, patient encountered several Madopar side effects: depressed level of consciousness on Sep 23, 2011 from SPAIN Additional patient health information: Male , 77 years of age, . Madopar dosage: Start Date : July 2011.
Multiple concurrent drugs taken:
  • Comtan (Start Date : July 2011)
  • Quetiapine Fumarate
  • Clonazepam (Start Date : July 2011)


Arthritis, Arthralgia (7774280-9)
Adverse event was reported on Sep 16, 2011 by a Female taking Madopar (Dosage: 125 Mg) was diagnosed with
  • parkinson's disease
  • arthritis
and. Location: UNITED KINGDOM , 72 years of age, Directly after, patient experienced the unwanted or unexpected Madopar side effects: arthritis, arthralgia.
Associated medications used:
  • Meloxicam (7.5 Mg)
  • Sulfasalazine (500 Mg)
  • Neupro (1 Mg)
  • Bisoprolol Fumarate (1.25 Mg)


Application Site Reaction, Application Site Vesicles, Application Site Erythema, Application Site Pain (7762688-7)
on Aug 15, 2011 Female from GERMANY , weighting 143.3 lb, was diagnosed with
  • restless legs syndrome
and was treated with Madopar. Patient felt the following Madopar side effects: application site reaction, application site vesicles, application site erythema, application site pain. Madopar dosage: Total Daily Dose:100/25.
Multiple prescriptions taken:
  • Ropinirole Hydrochloride
  • Neupro (3 Mg/24h)


Diarrhoea (7760121-2)
on Sep 10, 2011 Male from SWITZERLAND , weighting 189.6 lb, was treated with Madopar Dr. After Madopar was administered, patient encountered several Madopar side effects: diarrhoea. Madopar Dr dosage: N/A.
Multiple concurrent drugs taken:
  • Madopar Liquid
  • Neupro
Patient was hospitalized.

Oedema Peripheral, Malaise (7759781-1)
Patient was taking Madopar (madopar). Directly after, patient experienced the unwanted or unexpected Madopar side effects: oedema peripheral, malaise on Jun 06, 2011 from UNITED KINGDOM Additional patient health information: Male , 76 years of age, . Madopar (madopar) dosage: N/A.
Associated medications used:
  • Apo-go Ampoules (apo-go) (apomorphine Hydrochloride) (apomorphine Hydr (7 Mg, 1 In 1 Hr)
  • Apo-go Ampoules (apo-go) (apomorphine Hydrochloride) (apomorphine Hydr (7 Mg, 1 In 1 Hr)


Haemorrhoidal Haemorrhage (7627236-0)
Adverse event was reported on Jul 01, 2011 by a Male taking Madopar (benserazide Hydrochloride, Levodopa) (Dosage: N/A) . Location: TAIWAN, PROVINCE OF CHINA , 79 years of age, weighting 154.3 lb, Patient felt the following Madopar side effects: haemorrhoidal haemorrhage.
Multiple prescriptions taken:
  • Glucophage
  • Acetylsalicylic Acid Srt
  • Pletal
  • Pletal
  • Seroquel
  • Amaryl
  • Nootropil (piracetam)
Patient was hospitalized.

Judgement Impaired, Parkinson's Disease, Fall, Nocturia, Abnormal Behaviour, Freezing Phenomenon, Dissociative Identity Disorder, Tremor, Dyskinesia (7611109-3)
on Jun 20, 2011 Male from FRANCE , 71 years of age, was treated with Madopar. After Madopar was administered, patient encountered several Madopar side effects: judgement impaired, parkinson's disease, fall, nocturia, abnormal behaviour, freezing phenomenon, dissociative identity disorder, tremor, dyskinesia. Madopar dosage: N/A.
Multiple concurrent drugs taken:
  • Pramipexole Dihydrochloride (See Image)
  • Pramipexole Dihydrochloride (See Image)
  • Pramipexole Dihydrochloride (See Image)
  • Sinemet
  • Azilect
  • Requip
  • Lorazepam
  • Penilex
Patient was hospitalized.

Gait Disturbance, Dizziness (7608531-8)
on Jul 04, 2011 Female from GERMANY , weighting 132.3 lb, was diagnosed with
  • parkinson's disease
  • pain
  • lung neoplasm malignant
and was treated with Madopar. Directly after, patient experienced the unwanted or unexpected Madopar side effects: gait disturbance, dizziness. Madopar dosage: N/A.
Associated medications used:
  • Ibuprofen (400 Mg, Tid)
  • Sandostatin Lar (10 Mg, Unk)
  • Zopiclone (0.5 Df, Qd At Night)
Patient was hospitalized.

Gambling (7593413-0)
Patient was taking Madopar (madopar). Patient felt the following Madopar side effects: gambling on Jan 26, 2011 from DENMARK Additional patient health information: Patient , 59 years of age, . Madopar (madopar) dosage: Po.
Multiple prescriptions taken:
  • Pramipexole Dihydrochloride (1.5 Mg, Tid, Po)


Economic Problem, Pathological Gambling, Condition Aggravated (7592510-3)
Adverse event was reported on Jun 14, 2011 by a Patient taking Madopar (benserazide Hydrochloride, Levodopa) (benserazide Hydrochlori (Dosage: Oral) . Location: , 59 years of age, After Madopar was administered, patient encountered several Madopar side effects: economic problem, pathological gambling, condition aggravated.
Multiple concurrent drugs taken:
  • Pramipexole Dihydrochloride (4.5 Milligram, 3 In 1 D, Oral Use)


Diarrhoea (7578839-3)
on Jun 18, 2011 Male from SWITZERLAND , weighting 189.6 lb, was treated with Madopar Dr. Directly after, patient experienced the unwanted or unexpected Madopar side effects: diarrhoea. Madopar Dr dosage: N/A.
Associated medications used:
  • Nimotop
  • Lorazepam (1 Mg, If Required)
Patient was hospitalized.

Miosis, Coma (7574990-2)
on Jun 22, 2011 Patient from CHINA , 78 years of age, was treated with Madopar. Patient felt the following Madopar side effects: miosis, coma. Madopar dosage: 125 Mg, 3x/day.
Multiple prescriptions taken:
  • Idebenone (30 Mg, 3x/day)
  • Zoloft (50 Mg, 1x/day)
  • Nimotop (30 Mg, 3x/day)


Condition Aggravated, Pathological Gambling (7564056-X)
Patient was taking Madopar. After Madopar was administered, patient encountered several Madopar side effects: condition aggravated, pathological gambling on Jun 14, 2011 from UNITED KINGDOM Additional patient health information: Patient , 59 years of age, . Madopar dosage: N/A.
Multiple concurrent drugs taken:
  • Pramipexole Dihydrochloride (4.5 Mg)


Parkinsonism (7554502-X)
Adverse event was reported on Jun 09, 2011 by a Male taking Madopar (Dosage: N/A) . Location: JAPAN , 75 years of age, Directly after, patient experienced the unwanted or unexpected Madopar side effects: parkinsonism.
Associated medications used:
  • Paxil (20mg Per Day)
Patient was hospitalized.

Diarrhoea, Coeliac Disease (7552681-1)
on Jun 11, 2011 Male from SWITZERLAND , weighting 189.6 lb, was treated with Madopar Dr. Patient felt the following Madopar side effects: diarrhoea, coeliac disease. Madopar Dr dosage: N/A.
Multiple prescriptions taken:
  • Meto Zeroc
  • Claropram
  • Neupro
Patient was hospitalized.

Pneumonia, Refusal Of Treatment By Patient, Cardiopulmonary Failure (7546942-X)
on May 23, 2011 Female from GERMANY , 80 years of age, was treated with Madopar (madopar /00349201/). After Madopar was administered, patient encountered several Madopar side effects: pneumonia, refusal of treatment by patient, cardiopulmonary failure. Madopar (madopar /00349201/) dosage: N/A.
Multiple concurrent drugs taken:
  • Simvastatin
  • Clozapine
  • Apo-go Ampoules (apo-go) (apomorphine Hydrochloride) (apomorphine Hydr (80mg (80 Mg, 1 In 1 D),)
Patient was hospitalized.

Parkinsonism (7540560-5)
Patient was taking Madopar. Directly after, patient experienced the unwanted or unexpected Madopar side effects: parkinsonism on Jun 03, 2011 from JAPAN Additional patient health information: Male , 75 years of age, . Madopar dosage: N/A.
Associated medications used:
  • Paxil (20mg Per Day)
Patient was hospitalized.

Hallucination, Dysphoria (7438063-1)
Adverse event was reported on Apr 21, 2011 by a Female taking Madopar (Dosage: 1250 Mg, Unk) . Location: SWITZERLAND , 83 years of age, Patient felt the following Madopar side effects: hallucination, dysphoria.
Multiple prescriptions taken:
  • Comtan (200 Mg, Daily)
  • Comtan (100 Mg, Daily)


Loss Of Consciousness, Hypotension (7428880-6)
on Apr 14, 2011 Patient from JAPAN , 87 years of age, was treated with Madopar. After Madopar was administered, patient encountered several Madopar side effects: loss of consciousness, hypotension. Madopar dosage: N/A.
Multiple concurrent drugs taken:
  • Droxidopa
  • Livalo (1 Mg)
  • Bonalon 5mg
  • Micardis (40 Mg)
  • Risperdal


Neutropenia (7418369-2)
on Apr 07, 2011 Male from GERMANY , weighting 198.4 lb, was diagnosed with
  • parkinson's disease
and was treated with Madopar. Directly after, patient experienced the unwanted or unexpected Madopar side effects: neutropenia. Madopar dosage: 200mg Three Times Per Day.
Associated medications used:
  • Tamiflu (150mg Per Day)
  • Aspirin (100mg Per Day)
  • Nexium (20mg Per Day)
  • Zanamivir
Patient was hospitalized.

Showing 1-25 of 62 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Madopar Information

More About Madopar

Side Effects reported to FDA: 62. View Madopar Adverse Reports

Madopar safety alerts: No

Reported deaths: 6

Reported hospitalizations: 22

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