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Review Maprotiline Safety Reports submitted to FDA

Total Maprotiline reports: 5.
Maprotiline FDA safety alerts: No.
   Reported hospitalizations: 3.
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FDA Reported Maprotiline Side Effects: extrapyramidal disorder, tremor, parkinsonism, parkinsonian gait, constipation, bradykinesia, therapeutic agent toxicity, overdose, intubation, glasgow coma scale abnormal, neurotoxicity.
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Maprotiline Side Effects Report #5602115-9
Consumer or non-health professional from JAPAN reported MAPROTILINE problem on Jan 16, 2008. Female patient, 72 years of age, was diagnosed with depression and was treated with MAPROTILINE. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, labile blood pressure, nausea, neuroleptic malignant syndrome, pyrexia, rhabdomyolysis, urinary retention, vomiting. MAPROTILINE dosage: unknown. During the same period patient was treated with HALOPERIDOL, CLOMIPRAMINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Maprotiline Side Effects Report #5405668-9
MAPROTILINE problem was reported by a Consumer or non-health professional from JAPAN on July 25, 2007. Female patient, 67 years of age, was diagnosed with depression and was treated with MAPROTILINE. After drug was administered, patient experienced the following problems/side effects: extrapyramidal disorder. MAPROTILINE dosage: unknown. During the same period patient was treated with MAPROTILINE HYDROCHLORIDE, MAPROTILINE HYDROCHLORIDE, GLIMEPIRIDE, PAROXETINE HYDROCHLORIDE, NITRAZEPAM, QUAZEPAM, BIPERIDEN HYDROCHLORIDE, BIPERIDEN HYDROCHLORIDE. Patient recovered.

Maprotiline Side Effects Report #5410837-8
Consumer or non-health professional from JAPAN reported MAPROTILINE problem on Aug 03, 2007. Female patient, 67 years of age, was diagnosed with depression and was treated with MAPROTILINE. After drug was administered, patient experienced the following problems/side effects: bradykinesia, constipation, extrapyramidal disorder, parkinsonian gait, parkinsonism, tremor. MAPROTILINE dosage: 100 MG, QD. During the same period patient was treated with MAPROTILINE HYDROCHLORIDE, GLIMEPIRIDE, PAROXETINE HYDROCHLORIDE, NITRAZEPAM, QUAZEPAM, BIPERIDEN HYDROCHLORIDE, BIPERIDEN HYDROCHLORIDE, MILNACIPRAN. Patient recovered.

Maprotiline Side Effects Report #5396147-6
MAPROTILINE problem was reported by a Health Professional from TURKEY on July 19, 2007. Female patient, 37 years of age, was diagnosed with overdose and was treated with MAPROTILINE. After drug was administered, patient experienced the following problems/side effects: glasgow coma scale abnormal, intubation, overdose, therapeutic agent toxicity. MAPROTILINE dosage: 700 MG. During the same period patient was treated with OLANZAPINE. Patient was hospitalized. Patient recovered.

Maprotiline Side Effects Report #5396147-6
Health Professional from TURKEY reported MAPROTILINE problem on July 19, 2007. Female patient, 37 years of age, was diagnosed with overdose and was treated with MAPROTILINE. After drug was administered, patient experienced the following problems/side effects: glasgow coma scale abnormal, intubation, overdose, therapeutic agent toxicity. MAPROTILINE dosage: 700 MG. During the same period patient was treated with OLANZAPINE. Patient was hospitalized. Patient recovered.


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