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Mebeverine Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 26 

Diarrhoea Haemorrhagic, Swelling Face, Malaise, Oral Pain, Anxiety, Tremor, Clostridial Infection, Paraesthesia, Vomiting (8345279-9)
on May 04, 2012 Female from UNITED KINGDOM , 69 years of age, was treated with Mebeverine. Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: diarrhoea haemorrhagic, swelling face, malaise, oral pain, anxiety, tremor, clostridial infection, paraesthesia, vomiting. Mebeverine dosage: Unk Unk, Bid.
Associated medications used:
  • Theophylline (Unk Unk, Bid)
  • Avelox (1 Df, Qd)
  • Fluticasone Propionate/salmeterol (Unk Unk, Bid)
  • Calceos (Unk Unk, Bid)
  • Avelox (400 Mg, Qd)
  • Ventolin Nebules P.f. (Dosage: 5mg Tqds)
  • Alendronic Acid (Unk Unk, Ow)
Patient was hospitalized.

Chest Pain, Hyponatraemia, Contusion, Thrombocytopenia, Burning Sensation (8182221-8)
Patient was taking Mebeverine Hydrochloride. Patient felt the following Mebeverine side effects: chest pain, hyponatraemia, contusion, thrombocytopenia, burning sensation on Feb 23, 2012 from UNITED KINGDOM Additional patient health information: Female , 61 years of age, weighting 104.7 lb, . Mebeverine Hydrochloride dosage: N/A.
Multiple prescriptions taken:
  • Paroxetine
  • Nitroglycerin
  • Diltiazem Hcl
  • Gabapentin
  • Paroxetine (20 Mg, Once/single)
  • Acidex
  • Omeprazole
  • Albuterol
Patient was hospitalized.

Urine Flow Decreased (8174150-0)
Adverse event was reported on Feb 16, 2012 by a Male taking Mebeverine Hydrochloride(mebeverine Hydrochloride) (Dosage: N/A) . Location: , 81 years of age, weighting 178.6 lb, After Mebeverine was administered, patient encountered several Mebeverine side effects: urine flow decreased.
Multiple concurrent drugs taken:
  • Ispaghula Husk (plantago Ovata Husk)
  • Viscotears(carbomer)
  • Finasteride
  • Warfarin Sodium
  • Sotalol Hcl
  • Doxazosin Mesylate


Pancreatitis Acute (8119989-2)
on Jan 27, 2012 Female from UNITED KINGDOM , 42 years of age, weighting 207.5 lb, was treated with Mebeverine. Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: pancreatitis acute. Mebeverine dosage: 1 Tab, Tid.
Associated medications used:
  • Ranitidine (150 Unk, Unk)
  • Metformin Hcl (1000 Mg, Qd)
  • Glimepirid (2 Mg, Qd)
  • Amitriptyline Hcl (50 Unk, Unk)
  • Folic Acid (5 Mg, Unk)
  • Victoza (1.2 Mg, Qd)
  • Etoricoxib (1 Tab, Qd)
  • Acetaminophen And Codeine Phosphate
Patient was hospitalized.


Vertigo, Visual Impairment, Hypoaesthesia, Migraine, Blood Pressure Increased, Vision Blurred, Dizziness (7963396-X)
on Nov 24, 2011 Female from DENMARK , 61 years of age, was treated with Mebeverine. Patient felt the following Mebeverine side effects: vertigo, visual impairment, hypoaesthesia, migraine, blood pressure increased, vision blurred, dizziness. Mebeverine dosage: N/A.
Multiple prescriptions taken:
  • Aspirin
  • Bendroflumethiazine
  • Simvastatin
  • Indapamide
  • Diltiazem Hydrochloride (Po)
  • Diltiazem Hydrochloride (Po)
  • Sotalol Hcl


Visual Impairment, Dizziness, Cerebrovascular Accident, Vitreous Disorder, Vision Blurred, Cerebral Haematoma, Nausea, Product Substitution Issue (7936512-3)
Patient was taking Mebeverine (mebeverine). After Mebeverine was administered, patient encountered several Mebeverine side effects: visual impairment, dizziness, cerebrovascular accident, vitreous disorder, vision blurred, cerebral haematoma, nausea, product substitution issue on Nov 15, 2011 from Additional patient health information: Female , 61 years of age, . Mebeverine (mebeverine) dosage: N/A.
Multiple concurrent drugs taken:
  • Indapamide
  • Diltiazem ((200 Mg), Oral)
  • Bisoprolol Fumarate
  • Simvastatin
  • Bendroflumethiazide (bendroflumethiazide)
  • Dandelion ( Taraxacum Officinale)
  • Losartan Potassium
  • Diltiazem Hydrochloride ((200 Mg, 1 In 1 D), Oral)


Autoimmune Hepatitis, Oedema Peripheral (7919212-5)
Adverse event was reported on Nov 08, 2011 by a Female taking Mebeverine (Dosage: N/A) . Location: UNITED KINGDOM , 65 years of age, Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: autoimmune hepatitis, oedema peripheral.
Associated medications used:
  • Dothiepin Hydrochloride
  • Albuterol Sulfate Autohaler
  • Nitrofurantoin
  • Lansoprazole
  • Fluconazole
  • Acetaminophen


Suicide Attempt, Agitation, Intentional Overdose (7889896-9)
on Oct 29, 2011 Male from GERMANY , weighting 198.4 lb, was treated with Mebeverine. Patient felt the following Mebeverine side effects: suicide attempt, agitation, intentional overdose. Mebeverine dosage: 135mg See Dosage Text.
Multiple prescriptions taken:
  • Sertraline Hydrochloride (50mg See Dosage Text)
  • Lamictal (50mg See Dosage Text)
  • Voltaren (75mg See Dosage Text)
  • Alcohol


Renal Failure Acute, Hypoglycaemia (7720079-9)
on Aug 15, 2011 Male from , 35 years of age, was treated with Mebeverine (mebeverine). After Mebeverine was administered, patient encountered several Mebeverine side effects: renal failure acute, hypoglycaemia. Mebeverine (mebeverine) dosage: N/A.
Multiple concurrent drugs taken:
  • Glimepiride (4 Mg (4 Mg, 1 In 1 D), Oral)
  • Metformin Hcl (2 Gm (1 Gm, 2 In 1 D), Oral)
  • Bisoprolol Fumarate
  • Digoxin
  • Ramipril (10 Mg ( 10 Mg, 1 In 1 D), Oral)
  • Bumetanide
Patient was hospitalized.

Lethargy, Hypersomnia, Fatigue (7691595-3)
Patient was taking Mebeverine Hydrochloride. Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: lethargy, hypersomnia, fatigue on Aug 03, 2011 from UNITED KINGDOM Additional patient health information: Female , 43 years of age, weighting 103.6 lb, . Mebeverine Hydrochloride dosage: Unk.
Associated medications used:
  • Proguanil (Unk)
  • Levothyroxine Sodium (Unk)
  • Metronidazole (Unk)
  • Acetaminophen And Codeine Phosphate (Unk)
  • Hyoscine Hbr Hyt (Unk)
  • Levothyroxine Sodium (Unk)
  • Acetaminophen And Codeine Phosphate (Unk)
  • Norethindrone Acetate And Ethinyl Estradiol (Unk)


Circulatory Collapse, Overdose (7678582-6)
Adverse event was reported on Aug 09, 2011 by a Male taking Mebeverine Hydrochloride (Dosage: 135 Mg, Tid) . Location: UNITED KINGDOM , 37 years of age, Patient felt the following Mebeverine side effects: circulatory collapse, overdose.
Multiple prescriptions taken:
  • Albuterol (200 Ug, Unk)
  • Tramadol Hcl (Unk)
  • Celecoxib
  • Fluoxetine Hydrochloride (40 Mg, Qd)
  • Amitriptyline Hcl (75 Mg, Unk)
  • Cyclizine (50 Mg, Tid)
  • Ferrous Sulfate Tab (200 Mg, Tid)
  • Clenil (200 Ug, Bid)


Vision Blurred, Dry Skin, Nerve Injury, Paraesthesia Oral, Visual Impairment, Arthralgia (7578451-6)
on Jun 22, 2011 Male from NETHERLANDS , weighting 202.8 lb, was diagnosed with
  • crohn's disease
  • nausea
and was treated with Mebeverine. After Mebeverine was administered, patient encountered several Mebeverine side effects: vision blurred, dry skin, nerve injury, paraesthesia oral, visual impairment, arthralgia. Mebeverine dosage: N/A.
Multiple concurrent drugs taken:
  • Ranitidine
  • Diclofenac/misoprostol Sr (50/200 Mcg)
  • Perindopril Erbumine
  • Ranitidine
  • Humira
  • Bisoprolol
  • Hydrochlorothiazide


Agitation, Abdominal Pain Upper, Rash Macular, Malaise (7472455-X)
on May 05, 2011 Male from UNITED KINGDOM , 77 years of age, weighting 138.9 lb, was treated with Mebeverine. Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: agitation, abdominal pain upper, rash macular, malaise. Mebeverine dosage: 135 Mg, Tid.
Associated medications used:
  • Novolog (10 Iu, Unk)
  • Prednisolone (5 Mg, Qd)
  • Aspirin (75 Mg, Qd)
  • Bisoprolol (1.25 Mg, Qd)
  • Lansoprazole (30 Mg, Bid)
  • Fentanyl (50 Ug, Unk)
  • Warfarin (Unk Mg, Unk)
  • Adcal-d3 (1 Df, Bid)


Breast Cancer (7425053-8)
Patient was taking Mebeverine Hydrochloride. Patient felt the following Mebeverine side effects: breast cancer on Apr 13, 2011 from UNITED KINGDOM Additional patient health information: Female , 64 years of age, . Mebeverine Hydrochloride dosage: Unk.
Multiple prescriptions taken:
  • Acetaminophen And Codeine Phosphate (Unk)
  • Acetaminophen (Unk)
  • Didronel Pmo (Unk)
  • Enbrel (50 Mg, Weekly)
  • Neoclarityn (Unk)
  • Lansoprazole (Unk)
  • Prednisolone (Unk)
Patient was hospitalized.

Chronic Myeloid Leukaemia (7408071-5)
Adverse event was reported on Apr 04, 2011 by a Female taking Mebeverine (Dosage: N/A) . Location: UNITED KINGDOM , 44 years of age, weighting 141.1 lb, After Mebeverine was administered, patient encountered several Mebeverine side effects: chronic myeloid leukaemia.
Multiple concurrent drugs taken:
  • Danazol
  • Diazepam
  • Levothyroxine
  • Fluoxetine


Insomnia, Headache, Diarrhoea, Photophobia, Vomiting (7393764-9)
on Mar 23, 2011 Female from UNITED KINGDOM , 58 years of age, was treated with Mebeverine. Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: insomnia, headache, diarrhoea, photophobia, vomiting. Mebeverine dosage: Unk.
Associated medications used:
  • Simvastatin (Unk)
  • Vitamin A (Unk)
  • Enbrel (50 Mg, Weekly)
  • Metformin (Unk)
  • Co-dydramol (Unk)
  • Omeprazole (Unk)
  • Thyroxine


International Normalised Ratio Increased, Coagulation Time Prolonged (7305760-8)
on Feb 16, 2011 Female from UNITED KINGDOM , 74 years of age, was treated with Mebeverine Hydrochloride. Patient felt the following Mebeverine side effects: international normalised ratio increased, coagulation time prolonged. Mebeverine Hydrochloride dosage: N/A.
Multiple prescriptions taken:
  • Tramadol Hcl
  • Omeprazole
  • Pravastatin Sodium
  • Spiriva
  • Nitroglycerin
  • Warfarin Sodium
  • Furosemide
  • Terbutaline Sulfate


(6278893-5)
Patient was taking Mebeverine. on Jul 14, 2009 from UNITED KINGDOM Additional patient health information: Female , 32 years of age, . Mebeverine dosage: N/A.
Multiple concurrent drugs taken:
  • Chlordiazepoxide
  • Ethanol
  • Fluoxetine Hcl
  • Paracetamol
  • Valproic Acid


(6267805-6)
Adverse event was reported on Jun 30, 2009 by a Female taking Mebeverine (Dosage: N/A) . Location: UNITED KINGDOM , 32 years of age, .
Associated medications used:
  • Chlordiazepoxide
  • Ethanol
  • Fluoxetine Hcl
  • Paracetamol
  • Valproic Acid


(6257878-9)
on Jun 30, 2009 Female from UNITED KINGDOM , 32 years of age, was treated with Mebeverine. . Mebeverine dosage: N/A.
Multiple prescriptions taken:
  • Chlordiazepoxide
  • Ethanol
  • Fluoxetine Hcl
  • Paracetamol
  • Valproic Acid


Fatigue (6023666-1)
on Dec 10, 2008 Female from GERMANY , 53 years of age, weighting 154.3 lb, was treated with Mebeverine (mebeverine). After Mebeverine was administered, patient encountered several Mebeverine side effects: fatigue. Mebeverine (mebeverine) dosage: Oral.
Multiple concurrent drugs taken:
  • Zopiclone (zopiclone) (7.5 Mg) (Oral)
  • Chloraldurat (chloral Hydrate) (Oral)
  • Ibuprofen (Oral)
  • Ranitidine Hcl (Oral)
  • Seroquel (Oral)


Alcohol Use, Electrocardiogram Change, Fall, Tachycardia (6017533-7)
Patient was taking Mebeverine (mebeverine). Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: alcohol use, electrocardiogram change, fall, tachycardia on Dec 05, 2008 from GERMANY Additional patient health information: Female , 18 years of age, weighting 121.3 lb, . Mebeverine (mebeverine) dosage: Oral.
Associated medications used:
  • Ibuprofen (Oral)
  • Alcohol (ethanol) (0.5 L; Oral)
Patient was hospitalized.

Fall, Tachycardia (6003946-6)
Adverse event was reported on Nov 28, 2008 by a Female taking Mebeverine (mebeverine) (Dosage: Oral) . Location: GERMANY , 18 years of age, weighting 121.3 lb, Patient felt the following Mebeverine side effects: fall, tachycardia.
Multiple prescriptions taken:
  • Ibuprofen (Oral)


Asthma, Rash (5343535-X)
on May 21, 2007 Male from UNITED KINGDOM , 46 years of age, was diagnosed with
  • irritable bowel syndrome
  • onychomycosis
  • schizophrenia, paranoid type
  • asthma
and was treated with Mebeverine Hydrochloride. After Mebeverine was administered, patient encountered several Mebeverine side effects: asthma, rash. Mebeverine Hydrochloride dosage: 135 Mg, Tid.
Multiple concurrent drugs taken:
  • Terbinafine (250 Mg, Qd)
  • Priadel (3 Df, Qd)
  • Qvar 40 (Unk, Prn)
  • Salbutamol (Unk, Prn)
  • Sertraline (50 Mg, Qd)
  • Temazepam (10 Mg, Qd)


Epistaxis, Haemorrhage, Venous Thrombosis Limb (4771314-0)
on Nov 12, 2004 Female from GERMANY , 79 years of age, was diagnosed with
  • diverticulum
  • osteoporosis
  • pulmonary embolism
  • deep vein thrombosis
  • coronary artery disease
and was treated with Mebeverine Hydrochloride. Directly after, patient experienced the unwanted or unexpected Mebeverine side effects: epistaxis, haemorrhage, venous thrombosis limb. Mebeverine Hydrochloride dosage: N/A.
Associated medications used:
  • Cholecalciferol
  • Phenprocoumon
  • Phenprocoumon
  • Diltiazem Hydrochloride
  • Vioxx
  • Levothyroxine Sodium
  • Betahistine Hydrochloride
  • Vasotec Rpd
Patient was hospitalized and became disabled.

Showing 1-25 of 26 

Mebeverine Health Episodes

How Can Mebeverine Affect You?

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Mebeverine Information

More About Mebeverine

Side Effects reported to FDA: 26. View Mebeverine Adverse Reports

Mebeverine safety alerts: No

Reported deaths: 3

Reported hospitalizations: 3

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