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Mecobalamin Side Effects

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Common Mecobalamin Side Effects


The most commonly reported Mecobalamin side effects (click to view or check a box to report):

Blood Glucose Decreased (3)
Myelodysplastic Syndrome (3)
Cardiac Failure (3)
Blood Lactate Dehydrogenase Increased (2)
Decreased Appetite (2)
Blood Pressure Diastolic Decreased (2)
Alanine Aminotransferase Increased (2)
Aspartate Aminotransferase Increased (2)
Blood Alkaline Phosphatase Increased (2)
Pyrexia (2)
Hypoglycaemia (2)
Disseminated Intravascular Coagulation (2)
Dermatitis Exfoliative (2)
Dizziness (2)
Hepatic Function Abnormal (2)
Heart Rate Decreased (1)
Vomiting (1)
Haemorrhoids (1)
Headache (1)
Haematemesis (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Mecobalamin Side Effects Reported to FDA



Mecobalamin Side Effect Report#8476775-1
Flushing
This is a report of a 81-year-old female patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: NA, who was treated with Mecobalamin (dosage: NA, start time:
Jun 16, 2012), combined with:
  • Atorvastatin
  • Metformin Hcl
  • Omeprazole
  • Zetia
  • Micamlo
  • Opaprosmon
and developed a serious reaction and side effect(s): Flushing after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Mecobalamin treatment in female patients, resulting in Flushing side effect.
Mecobalamin Side Effect Report#8399632-8
Disseminated Intravascular Coagulation, Dermatitis Exfoliative
This report suggests a potential Mecobalamin Disseminated Intravascular Coagulation side effect(s) that can have serious consequences. A male patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: prophylaxis and used Mecobalamin (dosage: 500 Milligram) starting
Sep 16, 2011. After starting Mecobalamin the patient began experiencing various side effects, including: Disseminated Intravascular Coagulation, Dermatitis ExfoliativeAdditional drugs used concurrently:
  • Allopurinol (100 Milligram)
  • Betamethasone (5 Milligram)
  • Lenalidomide (25 Milligram)
  • Rabeprazole Sodium (10 Milligram)
  • Sulfamethoxazole (80 Milligram)
  • Betamethasone Valerate (Adequate Dose)
  • Fluconazole (100 Milligram)
The patient was hospitalized. Although Mecobalamin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Disseminated Intravascular Coagulation, may still occur.
Mecobalamin Side Effect Report#8395903-X
Disseminated Intravascular Coagulation, Dermatitis Exfoliative
This Disseminated Intravascular Coagulation problem was reported by a health professional from Japan. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: prophylaxis. On
Apr 30, 2012 this consumer started treatment with Mecobalamin (dosage: 500 Milligram). The following drugs were being taken at the same time:
  • Allopurinol (100 Milligram)
  • Lenalidomide (25 Milligram)
  • Corticosteroids
  • Fluid
  • Fluconazole (100 Milligram)
  • Rabeprazole Sodium (10 Milligram)
  • Betamethasone (5 Milligram)
  • Sulfamethoxazole (80 Milligram)
When using Mecobalamin, the patient experienced the following unwanted symptoms/side effects: Disseminated Intravascular Coagulation, Dermatitis ExfoliativeThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Disseminated Intravascular Coagulation, may become evident only after a product is in use by the general population.
Mecobalamin Side Effect Report#8364375-3
Inadequate Analgesia, Gastric Ulcer
This Inadequate Analgesia side effect was reported by a physician from Japan. A male patient (weight:NA) experienced the following symptoms/conditions: pain.The patient was prescribed Mecobalamin (drug dosage: 500 Mg X 1 Per 1 Day), which was initiated on
Nov 24, 2009. Concurrently used drugs:
  • Tramadol Hydrochloride And Acetaminophen
  • Amlodipine Besilate (5 Mg X 1 Per 1 Day)
  • Tramadol Hydrochloride And Acetaminophen
  • Maibastan (5 Mg X 1 Per 1 Day)
.After starting to take Mecobalamin the consumer reported adverse symptoms, such as: Inadequate Analgesia, Gastric UlcerThese side effects may potentially be related to Mecobalamin.
Mecobalamin Side Effect Report#8178321-9
Cardiac Failure, Myelodysplastic Syndrome
This is a report of a 85-year-old female patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: NA, who was treated with Mecobalamin (dosage: NA, start time:
Feb 26, 2011), combined with:
  • Rantac
  • Ferrous Citrate
  • Ceftriaxone Sodium
  • Azulfidine
  • Orencia (500 Mg, Ivd)
  • Prednisolone (Unk)
  • Candesartan Cilexetil
  • Epogin
and developed a serious reaction and side effect(s): Cardiac Failure, Myelodysplastic Syndrome after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Mecobalamin treatment in female patients, resulting in Cardiac Failure side effect.
Mecobalamin Side Effect Report#8165535-7
Myocardial Infarction
This report suggests a potential Mecobalamin Myocardial Infarction side effect(s) that can have serious consequences. A 62-year-old female patient (weight: NA) from China was diagnosed with the following symptoms/conditions: diabetic neuropathy and used Mecobalamin (dosage: NA) starting
Jan 01, 2009. After starting Mecobalamin the patient began experiencing various side effects, including: Myocardial InfarctionAdditional drugs used concurrently:
  • Humalog (Dose:21 Unit(s))
  • Insulin Glargine (Dose:20 Unit(s))
  • Solostar
  • Metformin Hcl
The patient was hospitalized. Although Mecobalamin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Myocardial Infarction, may still occur.
Mecobalamin Side Effect Report#8035558-7
Cholangitis Acute
This Cholangitis Acute problem was reported by a physician from Japan. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: pain. On
Dec 14, 2011 this consumer started treatment with Mecobalamin (dosage: NA). The following drugs were being taken at the same time:
  • Mucosta
  • Zolpidem
  • Sunbazon
  • Rebamipide
  • Gabexate Mesilate
  • Dextrose
  • Midazolam
  • Amlodin Od
When using Mecobalamin, the patient experienced the following unwanted symptoms/side effects: Cholangitis AcuteThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Cholangitis Acute, may become evident only after a product is in use by the general population.
Mecobalamin Side Effect Report#7920646-3
Rheumatoid Arthritis, Dementia
This Rheumatoid Arthritis side effect was reported by a physician from Japan. A 70-year-old female patient (weight:NA) experienced the following symptoms/conditions: arteriosclerosis.The patient was prescribed Mecobalamin (drug dosage: NA), which was initiated on
Feb 24, 2011. Concurrently used drugs:
  • Atorvastatin Calcium
  • Ketoprofen (Qs)
  • Quazepam
  • Sulpiride
  • Carbamazepine
  • Lansoprazole
  • Folic Acid
  • Ketoprofen (Qs)
.After starting to take Mecobalamin the consumer reported adverse symptoms, such as: Rheumatoid Arthritis, DementiaThese side effects may potentially be related to Mecobalamin. The patient was hospitalized.
Mecobalamin Side Effect Report#7909455-9
Vomiting, Haemorrhoids, Ingrowing Nail, Hyperkeratosis, Conjunctivitis
This is a report of a 50-year-old male patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: NA, who was treated with Mecobalamin (dosage: Unk, start time:
Sep 17, 2010), combined with:
  • Dexamethasone Sodium Phosphate (Unk)
  • Motilium (Unk)
  • Panitumumab (6 Mg/kg, Q2wk)
  • Panitumumab (6 Mg/kg, Q2wk)
  • Topotecan (150 Mg/m2, Q2wk)
  • Antebate (Unk)
  • Emend (Unk)
  • Posterisan (Unk)
and developed a serious reaction and side effect(s): Vomiting, Haemorrhoids, Ingrowing Nail, Hyperkeratosis, Conjunctivitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Mecobalamin treatment in male patients, resulting in Vomiting side effect.
Mecobalamin Side Effect Report#7861395-X
Gastrooesophageal Reflux Disease, Headache, Haematemesis
This report suggests a potential Mecobalamin Gastrooesophageal Reflux Disease side effect(s) that can have serious consequences. A 57-year-old female patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: diabetic neuropathy and used Mecobalamin (dosage: 500 Ug, 3x/day) starting
Jun 27, 2007. After starting Mecobalamin the patient began experiencing various side effects, including: Gastrooesophageal Reflux Disease, Headache, HaematemesisAdditional drugs used concurrently:
  • Mexitil (50 Mg, 2x/day)
  • Amitriptyline Hcl (10 Mg, 1x/day)
  • Glyburide (2.5 Mg, 1x/day)
  • Lyrica (75 Mg, 2x/day)
  • Glyburide (1.25 Mg, 1x/day)
  • Clonazepam (0.5 Mg, 1x/day)
  • Voglibose (0.3 Mg, 3x/day)
The patient was hospitalized. Although Mecobalamin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Gastrooesophageal Reflux Disease, may still occur.
Mecobalamin Side Effect Report#7790249-2
Diabetes Mellitus Inadequate Control, Blood Glucose Decreased
This Diabetes Mellitus Inadequate Control problem was reported by a physician from China. A 55-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Dec 24, 2010 this consumer started treatment with Mecobalamin (dosage: Unk). The following drugs were being taken at the same time:
  • Novorapid (1u+1u+1u Bolus)
  • Estazolam (Unk)
  • Aspirin (Unk)
  • Novolog (30 U, Bid)
  • Levemir (12u At Bed Time)
  • Novorapid (6u+6u+5.2u Bolus, 38.9u Basal (maximum))
  • Simvastatin (Unk)
  • Novorapid (6u+6u+7u Bolus)
When using Mecobalamin, the patient experienced the following unwanted symptoms/side effects: Diabetes Mellitus Inadequate Control, Blood Glucose DecreasedThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Diabetes Mellitus Inadequate Control, may become evident only after a product is in use by the general population.
Mecobalamin Side Effect Report#7774288-3
Cardiac Failure, Myelodysplastic Syndrome
This Cardiac Failure side effect was reported by a physician from Japan. A 85-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Mecobalamin (drug dosage: NA), which was initiated on
Feb 26, 2011. Concurrently used drugs:
  • Lasix
  • Prednisolone (Unk)
  • Mobic
  • Folic Acid
  • Rantac
  • Rheumatrex (2 Mg, 1 Week)
  • Cerocral
  • Amlodipine
.After starting to take Mecobalamin the consumer reported adverse symptoms, such as: Cardiac Failure, Myelodysplastic SyndromeThese side effects may potentially be related to Mecobalamin.
Mecobalamin Side Effect Report#7702962-3
Liver Carcinoma Ruptured, Blood Pressure Diastolic Decreased
This is a report of a male patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: NA, who was treated with Mecobalamin (dosage: 0.5 Mg, Unk, start time:
Jul 31, 2007), combined with:
  • Promac (150 Mg, Unk)
  • Candesartan Cilexetil (4 Mg, Unk)
  • Sigmart (15 Mg, Unk)
  • Lansoprazole (15 Mg, Unk)
  • Valsartan (40 Mg, Qd)
  • Gasmotin (15 Mg, Unk)
and developed a serious reaction and side effect(s): Liver Carcinoma Ruptured, Blood Pressure Diastolic Decreased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Mecobalamin treatment in male patients, resulting in Liver Carcinoma Ruptured side effect. The patient was hospitalized.
Mecobalamin Side Effect Report#7619013-1
Liver Disorder, Melaena, C-reactive Protein Increased, Gastrointestinal Haemorrhage, Rectal Ulcer Haemorrhage, Blood Albumin Decreased, Ascites
This report suggests a potential Mecobalamin Liver Disorder side effect(s) that can have serious consequences. A female patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: NA and used Mecobalamin (dosage: 1500 Mcg Daily) starting
Mar 14, 2011. After starting Mecobalamin the patient began experiencing various side effects, including: Liver Disorder, Melaena, C-reactive Protein Increased, Gastrointestinal Haemorrhage, Rectal Ulcer Haemorrhage, Blood Albumin Decreased, AscitesAdditional drugs used concurrently: NA.The patient was hospitalized. Although Mecobalamin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Liver Disorder, may still occur.
Mecobalamin Side Effect Report#7555498-7
Cardiac Failure, Myelodysplastic Syndrome
This Cardiac Failure problem was reported by a physician from Japan. A 85-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Feb 26, 2011 this consumer started treatment with Mecobalamin (dosage: NA). The following drugs were being taken at the same time:
  • Mucodyne
  • Ceftriaxone Sodium
  • Rantac
  • Cerocral
  • Candesartan Cilexetil
  • Rheumatrex (2 Mg, 1 Week)
  • Folic Acid
  • Prednisolone (Unk)
When using Mecobalamin, the patient experienced the following unwanted symptoms/side effects: Cardiac Failure, Myelodysplastic SyndromeAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Cardiac Failure, may become evident only after a product is in use by the general population.
Mecobalamin Side Effect Report#7511781-2
Hypotension, Blood Pressure Decreased, Renal Impairment, Hyperkalaemia, Dehydration, Decreased Appetite, Dizziness, Metabolic Acidosis, Heart Rate Decreased
This Hypotension side effect was reported by a health professional from Japan. A 68-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Mecobalamin (drug dosage: NA), which was initiated on
Mar 10, 2010. Concurrently used drugs:
  • Ternelin (tizanidine Hydrochloride)
  • Juvela (tocopheryl Acetate)
  • Celecoxib
  • Olmesartan Medoxomil (20 Mg (20 Mg, 1 In 1 D), Per Oral; 10 Mg (10 Mg, 1 In 1 D), Per Oral)
  • Olmesartan Medoxomil (20 Mg (20 Mg, 1 In 1 D), Per Oral; 10 Mg (10 Mg, 1 In 1 D), Per Oral)
  • Amaryl
  • Prorenal (limaprost)
  • Metformin Hydrochloride
.After starting to take Mecobalamin the consumer reported adverse symptoms, such as: Hypotension, Blood Pressure Decreased, Renal Impairment, Hyperkalaemia, Dehydration, Decreased Appetite, Dizziness, Metabolic Acidosis, Heart Rate DecreasedThese side effects may potentially be related to Mecobalamin. The patient was hospitalized.
Mecobalamin Side Effect Report#7480421-3
Blood Pressure Diastolic Decreased
This is a report of a male patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: NA, who was treated with Mecobalamin (dosage: 0.5 Mg, Unk, start time:
May 27, 2008), combined with:
  • Promac (150 Mg, Unk)
  • Candesartan Cilexetil (4 Mg, Unk)
  • Sigmart (15 Mg, Unk)
  • Takepron (15 Mg, Unk)
  • Gasmotin (15 Mg, Unk)
  • Valsartan (40 Mg, Qd)
and developed a serious reaction and side effect(s): Blood Pressure Diastolic Decreased after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Mecobalamin treatment in male patients, resulting in Blood Pressure Diastolic Decreased side effect.
Mecobalamin Side Effect Report#7335311-3
Malaise, Dizziness, Decreased Appetite
This report suggests a potential Mecobalamin Malaise side effect(s) that can have serious consequences. A 74-year-old male patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: NA and used Mecobalamin (dosage: Unk) starting
Dec 10, 2007. After starting Mecobalamin the patient began experiencing various side effects, including: Malaise, Dizziness, Decreased AppetiteAdditional drugs used concurrently:
  • Troxipide (Unk)
  • Pioglitazone Hydrochloride (Unk)
  • Metoclopramide Hcl (Unk)
  • Pilsicainide Hydrochloride (Unk)
  • Sulpiride (Unk)
  • Candesartan Cilexetil (Unk)
  • Warfarin Potassium (Unk)
  • Famvir (1500 Mg Daily)
The patient was hospitalized. Although Mecobalamin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Malaise, may still occur.
Mecobalamin Side Effect Report#7272653-4
Paronychia, Tremor, Chills, Vertigo, Dermatitis
This Paronychia problem was reported by a physician from Japan. A 74-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jul 29, 2010 this consumer started treatment with Mecobalamin (dosage: Unk Unk, Unk). The following drugs were being taken at the same time:
  • Livalo
  • Gasmotin
  • Aspirin
  • Lasix
  • Gaster D
  • Norvasc
  • Plavix
  • Lasix
When using Mecobalamin, the patient experienced the following unwanted symptoms/side effects: Paronychia, Tremor, Chills, Vertigo, DermatitisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Paronychia, may become evident only after a product is in use by the general population.
Mecobalamin Side Effect Report#7241462-4
Muscular Weakness, Stem Cell Transplant, Diffuse Large B-cell Lymphoma, Memory Impairment, Neoplasm Malignant, Metastases To Central Nervous System, Disorientation
This Muscular Weakness side effect was reported by a physician from Japan. A 52-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Mecobalamin (mecobalamin) (drug dosage: NA), which was initiated on
Feb 19, 2009. Concurrently used drugs:
  • Etoposide
  • Thymoglobulin (50 Mg, Qd, Intravenous)
  • Itraconazole
  • Cytarabine
  • Lansoprazole
  • Platelets, Concentrated (platelets, Concentrated)
  • Melphalan Hydrochloride
  • Rebamipide (rebamipide)
.After starting to take Mecobalamin (mecobalamin) the consumer reported adverse symptoms, such as: Muscular Weakness, Stem Cell Transplant, Diffuse Large B-cell Lymphoma, Memory Impairment, Neoplasm Malignant, Metastases To Central Nervous System, DisorientationThese side effects may potentially be related to Mecobalamin (mecobalamin). The patient was hospitalized.
Mecobalamin Side Effect Report#5945943-2
Epilepsy
This is a report of a 74-year-old patient (weight: NA) from Japan, suffering from the following health symptoms/conditions: NA, who was treated with Mecobalamin (dosage: Unk, start time:
Oct 02, 2008), combined with:
  • Plavix (75 Mg)
and developed a serious reaction and side effect(s): Epilepsy after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Mecobalamin treatment in patients, resulting in Epilepsy side effect.
Mecobalamin Side Effect Report#5243541-X
Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Glucose Decreased, Blood Lactate Dehydrogenase Increased, Hepatic Function Abnormal, Hypoglycaemia, Pyrexia
This report suggests a potential Mecobalamin Alanine Aminotransferase Increased side effect(s) that can have serious consequences. A 24-year-old male patient (weight: NA) from Japan was diagnosed with the following symptoms/conditions: hypoaesthesia and used Mecobalamin (dosage: Unk, Unk) starting
Jul 19, 1997. After starting Mecobalamin the patient began experiencing various side effects, including: Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Glucose Decreased, Blood Lactate Dehydrogenase Increased, Hepatic Function Abnormal, Hypoglycaemia, PyrexiaAdditional drugs used concurrently:
  • Goshajinkigan (Unk, Unk)
  • Insulin
  • Troglitazone (Unk, Unk)
  • Tegretol
The patient was hospitalized. Although Mecobalamin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Alanine Aminotransferase Increased, may still occur.
Mecobalamin Side Effect Report#5213962-X
Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Glucose Decreased, Blood Lactate Dehydrogenase Increased, Hepatic Function Abnormal, Hypoglycaemia, Pyrexia
This Alanine Aminotransferase Increased problem was reported by a health professional from Japan. A 24-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: hypoaesthesia. On
Jul 19, 1997 this consumer started treatment with Mecobalamin (dosage: NA). The following drugs were being taken at the same time:
  • Goshajinkigan
  • Insulin
  • Troglitazone
  • Carbamazepine
When using Mecobalamin, the patient experienced the following unwanted symptoms/side effects: Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Glucose Decreased, Blood Lactate Dehydrogenase Increased, Hepatic Function Abnormal, Hypoglycaemia, PyrexiaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Alanine Aminotransferase Increased, may become evident only after a product is in use by the general population.



The appearance of Mecobalamin on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Mecobalamin reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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