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Review Meperidine Safety Reports submitted to FDA

Total Meperidine reports: 25.
Meperidine FDA safety alerts: No.
Reported deaths: 3    Reported hospitalizations: 9.
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FDA Reported Meperidine Side Effects: cardio-respiratory arrest, hypotension, death, loss of consciousness, convulsion, confusional state, nausea, respiratory depression, pruritus, depressed level of consciousness, heart rate increased.
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Meperidine Side Effects Report #5678110-0
Physician from CANADA reported MEPERIDINE problem on Mar 10, 2008. Male patient, 27 years of age, was diagnosed with chills, enterococcal sepsis, pathogen resistance and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: serotonin syndrome. MEPERIDINE dosage: 25 MG, TWICE, INTRAVENOUS. During the same period patient was treated with LINEZOLID, CYTARABINE, DAUNORUBICIN, AMBISOME, TIMENTIN, TOBRAMYCIN, VANCOMYCIN. Patient recovered.

Meperidine Side Effects Report #5628945-5
MEPERIDINE problem was reported by a Physician from UNITED STATES on Feb 04, 2008. Male patient, 53 years of age, was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest. MEPERIDINE dosage: unknown. Patient died.

Meperidine Side Effects Report #5628948-0
Physician from UNITED STATES reported MEPERIDINE problem on Feb 04, 2008. Female patient, 50 years of age, was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest. MEPERIDINE dosage: unknown. Patient died.

Meperidine Side Effects Report #5584998-4
MEPERIDINE problem was reported by a Pharmacist from UNITED STATES on Jan 07, 2008. Female patient, 41 years of age, weighting 173.1 lb, was diagnosed with abdominal pain and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: convulsion. MEPERIDINE dosage: 10MG WITH 10 MINS DELAY IV. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5599329-3
Consumer or non-health professional from UNITED STATES reported MEPERIDINE problem on Jan 11, 2008. Male patient, 53 years of age, was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest. MEPERIDINE dosage: unknown. Patient died on 01/01/2006.

Meperidine Side Effects Report #5614847-7
MEPERIDINE problem was reported by a Physician from AUSTRALIA on Jan 21, 2008. Female patient, 17 years of age, was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: agitation, clonus, delirium, grand mal convulsion, hyperreflexia, loss of consciousness, miosis, mydriasis, myoclonus. MEPERIDINE dosage: 200 X 50 MG ORAL ONCE. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5557208-1
Consumer or non-health professional from UNITED STATES reported MEPERIDINE problem on Dec 11, 2007. Female patient, 73 years of age, weighting 156.5 lb, was diagnosed with convulsion and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: cyanosis. MEPERIDINE dosage: unknown. During the same period patient was treated with MIDAZOLAM. Patient recovered.

Meperidine Side Effects Report #5517906-2
MEPERIDINE problem was reported by a Pharmacist from UNITED STATES on Oct 29, 2007. Male patient, 20 years of age, weighting 160.9 lb, was diagnosed with sedation and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: aggression, agitation, blood pressure increased, confusional state, heart rate increased, respiratory rate increased, somnolence, speech disorder. MEPERIDINE dosage: 50 MG,. During the same period patient was treated with PROPOFOL, PROMETHAZINE. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5530142-9
Health Professional from UNITED STATES reported MEPERIDINE problem on Nov 22, 2007. Male patient, 32 years of age, was diagnosed with postoperative analgesia and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: infusion related reaction, infusion site erythema. MEPERIDINE dosage: 25MG PRN IV. Patient recovered.

Meperidine Side Effects Report #5530157-0
MEPERIDINE problem was reported by a Health Professional from UNITED STATES on Nov 28, 2007. Male patient, 37 years of age, weighting 249.1 lb, was diagnosed with procedural pain and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: infusion related reaction, infusion site erythema. MEPERIDINE dosage: 25MG PRN IV. Patient recovered.

Meperidine Side Effects Report #5530165-X
Health Professional from UNITED STATES reported MEPERIDINE problem on Nov 28, 2007. Female patient, 87 years of age, weighting 141.1 lb, was diagnosed with procedural pain and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: infusion related reaction, infusion site erythema, pruritus. MEPERIDINE dosage: 25MG PRN IV. Patient recovered.

Meperidine Side Effects Report #5484693-6
MEPERIDINE problem was reported by a Physician from UNITED STATES on Sept 27, 2007. Female patient, 44 years of age, was diagnosed with pain, depression and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: breakthrough pain, disorientation, illusion, paranoia, platelet count increased, respiratory rate increased, serotonin syndrome, white blood cell count increased, wound infection. MEPERIDINE dosage: 230 MG TOTAL OVER 8 HOURS, PARENTERAL. During the same period patient was treated with CITALOPRAM HYDROBROMIDE, HYDROMORPHONE, HYDROCODONE BITARTRATE, PROMETHAZINE, GATIFLOXACIN, ZOLPIDEM TARTRATE, LANSOPRAZOLE, ENOXAPARIN. Patient recovered.

Meperidine Side Effects Report #5485460-X
Pharmacist from UNITED STATES reported MEPERIDINE problem on Oct 10, 2007. Male patient, 59 years of age, was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: swollen tongue. MEPERIDINE dosage: unknown. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5490512-4
MEPERIDINE problem was reported by a Pharmacist from UNITED STATES on Oct 17, 2007. Female patient, 46 years of age, weighting 187.4 lb, was diagnosed with sickle cell anaemia with crisis and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: convulsion, sickle cell anaemia with crisis. MEPERIDINE dosage: 100 MG Q 2 H PRN. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5455648-2
Pharmacist from UNITED STATES reported MEPERIDINE problem on Sept 13, 2007. Male patient, 38 years of age, was diagnosed with endoscopy and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: sedation. MEPERIDINE dosage: 50MG ONCE IV. During the same period patient was treated with MIDAZOLAM. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5475863-1
MEPERIDINE problem was reported by a Physician from PUERTO RICO on Aug 03, 2006. Female patient, 45 years of age, weighting 175.0 lb, was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, lethargy, overdose, respiratory depth decreased, respiratory distress. MEPERIDINE dosage: 15 MG BOLUS, INTRAVENOUS; 15MG/HR, 10MIN BOLUS LOCKOUT, 200MG/4HR, CONTINUOUS. During the same period patient was treated with PHENERGAN. Patient recovered.

Meperidine Side Effects Report #5406088-3
Health Professional from UNITED STATES reported MEPERIDINE problem on Aug 02, 2007. Female patient, 25 years of age, was diagnosed with pain and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: pain, pruritus, rash, urticaria. MEPERIDINE dosage: 50MG IVP X1. Patient recovered.

Meperidine Side Effects Report #5408373-8
MEPERIDINE problem was reported by a Pharmacist from UNITED STATES on Aug 06, 2007. Male patient, 75 years of age, was diagnosed with pain and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: hypotension, respiratory depression, tachycardia. MEPERIDINE dosage: 12.5MG ONCE IV. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5409458-2
Consumer or non-health professional from UNITED STATES reported MEPERIDINE problem on Aug 02, 2007. Female patient, 44 years of age, was diagnosed with pain, nausea, wound infection and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: nausea, serotonin syndrome. MEPERIDINE dosage: unknown. During the same period patient was treated with CITALOPRAM, HYDROMORPHONE, ACETAMINOPHEN AND HYDROCODONE BITARTRATE, PROMETHAZINE, GATIFLOXACIN, ZOLPIDEM TARTRATE, LANSOPRAZOLE, ENOXAPARIN. Patient recovered.

Meperidine Side Effects Report #5409481-8
MEPERIDINE problem was reported by a Pharmacist from UNITED STATES on Aug 07, 2007. Male patient, 37 years of age, was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: anaphylactic reaction, angioedema. MEPERIDINE dosage: unknown. During the same period patient was treated with MIDAZOLAM. Patient recovered.

Meperidine Side Effects Report #5416791-7
Consumer or non-health professional from UNITED STATES reported MEPERIDINE problem on Aug 15, 2007. Female patient, 66 years of age, weighting 286.2 lb, was diagnosed with pulmonary embolism and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: respiratory distress. MEPERIDINE dosage: 75 MG -1/2 RECEIVED- ONCE -PRN- IV. Patient recovered.

Meperidine Side Effects Report #5399015-9
MEPERIDINE problem was reported by a Pharmacist from UNITED STATES on July 23, 2007. Male patient, 84 years of age, weighting 103.8 lb, was diagnosed with sedation and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: bradycardia, hypotension. MEPERIDINE dosage: 50 MG ONCE IV. During the same period patient was treated with MIDAZOLAM HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5402606-X
Physician from UNITED STATES reported MEPERIDINE problem on July 22, 2007. Female patient, 44 years of age, was diagnosed with breakthrough pain, depression and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: agitation, depression, disorientation, hypertension, illusion, nausea, paranoia, pyrexia. MEPERIDINE dosage: unknown. During the same period patient was treated with CITALOPRAM HYDROBROMIDE, FENTANYL, HYDROMORPHONE, HYRDOCODONE BITARTRATE, PROMETHAZINE, GATIFLOXACIN, ZOLPIDEM TARTRATE, LANSOPRAZOLE. Patient recovered.

Meperidine Side Effects Report #5399015-9
MEPERIDINE problem was reported by a Pharmacist from UNITED STATES on July 23, 2007. Male patient, 84 years of age, weighting 103.8 lb, was diagnosed with sedation and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: bradycardia, hypotension. MEPERIDINE dosage: 50 MG ONCE IV. During the same period patient was treated with MIDAZOLAM HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Meperidine Side Effects Report #5402606-X
Physician from UNITED STATES reported MEPERIDINE problem on July 22, 2007. Female patient, 44 years of age, was diagnosed with breakthrough pain, depression and was treated with MEPERIDINE. After drug was administered, patient experienced the following problems/side effects: agitation, depression, disorientation, hypertension, illusion, nausea, paranoia, pyrexia. MEPERIDINE dosage: unknown. During the same period patient was treated with CITALOPRAM HYDROBROMIDE, FENTANYL, HYDROMORPHONE, HYRDOCODONE BITARTRATE, PROMETHAZINE, GATIFLOXACIN, ZOLPIDEM TARTRATE, LANSOPRAZOLE. Patient recovered.


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