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Metformine Side Effects

PatientsVille

Common Metformine Side Effects


The most commonly reported Metformine side effects (click to view or check a box to report):

Lactic Acidosis (8)
Renal Failure (5)
Renal Failure Acute (4)
Overdose (3)
Nausea (3)
Malaise (3)
Conjunctival Haemorrhage (2)
Hypoglycaemia (2)
Completed Suicide (2)
Gout (2)
Jaundice (2)
Ecchymosis (2)
Diarrhoea (2)
Tachycardia Paroxysmal (2)
Skin Reaction (2)
Petechiae (2)
Suicide Attempt (2)
Toxicity To Various Agents (2)
Vomiting (2)
Metabolic Acidosis (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Metformine Side Effects Reported to FDA



Metformine Side Effect Report#9964473
Lactic Acidosis, Renal Failure
This is a report of a 78-year-old male patient (weight: NA) from NL, suffering from the following health symptoms/conditions: diabetes mellitus, who was treated with Metformine Tablet 850mg (dosage: Extra Info: Has Recently Been Increased From 2 Times Daily 1000 Mg To 3 Times Daily 850 Mg.., start time:
Feb 10, 2014), combined with:
  • Lisinopril Tablet 10mg (10 Milligram Daily;)
  • Spironolacton Tablet 25mg (25 Milligram Daily;)
  • Furabid Capsule Mga 100mg (200 Milligram Daily; Prolonged-release Capsule)
  • Glimepiride Tablet 2mg (2 Milligram Daily;)
  • Xatral Xr Tablet Mva 10mg (10 Milligram Daily;)
  • Escitalopram Tablet 10mg (10 Milligram Daily;)
and developed a serious reaction and side effect(s): Lactic Acidosis, Renal Failure after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metformine Tablet 850mg treatment in male patients, resulting in Lactic Acidosis side effect. The patient was hospitalized.
Metformine Side Effect Report#9948947
Incorrect Dose Administered, Hypoglycaemic Coma, Pyrexia
This report suggests a potential Metformine Incorrect Dose Administered side effect(s) that can have serious consequences. A 63-year-old male patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: hyperglycaemia and used Metformine (dosage: NA) starting
Nov 16, 2013. After starting Metformine the patient began experiencing various side effects, including: Incorrect Dose Administered, Hypoglycaemic Coma, PyrexiaAdditional drugs used concurrently:
  • Amarel
  • Onglyza
The patient was hospitalized. Although Metformine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Incorrect Dose Administered, may still occur.
Metformine Side Effect Report#9870602
Toxicity To Various Agents
This Toxicity To Various Agents problem was reported by a consumer or non-health professional from US. A 53-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Metformine (metformin) (dosage: NA). The following drugs were being taken at the same time: NA. When using Metformine (metformin), the patient experienced the following unwanted symptoms/side effects: Toxicity To Various AgentsAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Toxicity To Various Agents, may become evident only after a product is in use by the general population.
Metformine Side Effect Report#9869602
Metabolic Acidosis, Renal Failure, Body Temperature Increased, Heart Rate Increased, Haemodialysis, Biopsy Kidney Abnormal, Renal Tubular Disorder, Nephritis
This Metabolic Acidosis side effect was reported by a consumer or non-health professional from FR. A 54-year-old female patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Metformine (metformin) (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Fenofibrate
  • Flunarizine
  • Pantoprazole
  • Hydrocortisone
  • Alendronic Acid
  • Methotrexate
  • Paroxetine
  • Clorazepate
.After starting to take Metformine (metformin) the consumer reported adverse symptoms, such as: Metabolic Acidosis, Renal Failure, Body Temperature Increased, Heart Rate Increased, Haemodialysis, Biopsy Kidney Abnormal, Renal Tubular Disorder, NephritisThese side effects may potentially be related to Metformine (metformin). The patient was hospitalized.
Metformine Side Effect Report#9736507
Alopecia
This is a report of a 52-year-old male patient (weight: NA) from FR, suffering from the following health symptoms/conditions: NA, who was treated with Metformine Teva (dosage: NA, start time: 200901), combined with:
  • Pravadual (1 Dosage Forms Daily;)
  • Pravadual
  • Ramipril Biogaran 10mg (1 Dosage Forms Daily;)
  • Procoralan (1 Dosage Forms Daily;)
  • Ezetrol 10mg (1 Dosage Forms Daily;)
  • Verapamil Biogaran L.p 240mg (1 Dosage Forms Daily;)
  • Novonorm (1 Dosage Forms Daily;)
  • Novorapid
and developed a serious reaction and side effect(s): Alopecia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metformine Teva treatment in male patients, resulting in Alopecia side effect.
Metformine Side Effect Report#9731815
Completed Suicide, Overdose
This report suggests a potential Metformine (metformin) Completed Suicide side effect(s) that can have serious consequences. A 48-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Metformine (metformin) (dosage: NA) starting NS. After starting Metformine (metformin) the patient began experiencing various side effects, including: Completed Suicide, OverdoseAdditional drugs used concurrently:
  • Amlodipine W/valsartan
  • Metoprolol (metoprolol)
Although Metformine (metformin) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Completed Suicide, may still occur.
Metformine Side Effect Report#9626873
Bladder Neoplasm, Renal Failure Acute, Sepsis, Lactic Acidosis
This Bladder Neoplasm problem was reported by a pharmacist from NL. A 76-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus. On 2012 this consumer started treatment with Metformine Tablet 500mg (dosage: 1500 Milligram Daily; 3 Times A Day 1 Piece). The following drugs were being taken at the same time:
  • Pravastatine Tablet 40mg (40 Milligram Daily; 1 Time A Day 1 Piece)
When using Metformine Tablet 500mg, the patient experienced the following unwanted symptoms/side effects: Bladder Neoplasm, Renal Failure Acute, Sepsis, Lactic AcidosisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Bladder Neoplasm, may become evident only after a product is in use by the general population.
Metformine Side Effect Report#9624671
Lactic Acidosis, Renal Failure, Hepatic Failure, Vomiting
This Lactic Acidosis side effect was reported by a physician from NL. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Metformine Tablet 1000mg (drug dosage: 3000 Milligram Daily;), which was initiated on 2006. Concurrently used drugs:
  • Glimepiride Tablet 1mg (2 Milligram Daily;)
  • Enalapril Tablet 20mg (40 Milligram Daily;)
.After starting to take Metformine Tablet 1000mg the consumer reported adverse symptoms, such as: Lactic Acidosis, Renal Failure, Hepatic Failure, VomitingThese side effects may potentially be related to Metformine Tablet 1000mg. The patient was hospitalized.
Metformine Side Effect Report#9447886
Premature Rupture Of Membranes, Abortion Spontaneous, Exposure During Pregnancy, Myalgia, Pregnancy, Gestational Diabetes, Shortened Cervix, Amniotic Cavity Infection, Radiculitis
This is a report of a 32-year-old female patient (weight: NA) from FR, suffering from the following health symptoms/conditions: NA, who was treated with Metformine (dosage: NA, start time: NS), combined with:
  • Insulin
and developed a serious reaction and side effect(s): Premature Rupture Of Membranes, Abortion Spontaneous, Exposure During Pregnancy, Myalgia, Pregnancy, Gestational Diabetes, Shortened Cervix, Amniotic Cavity Infection, Radiculitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metformine treatment in female patients, resulting in Premature Rupture Of Membranes side effect.
Metformine Side Effect Report#9408980
Suicide Attempt, Overdose, Toxicity To Various Agents, Lactic Acidosis, Shock
This report suggests a potential Metformine Suicide Attempt side effect(s) that can have serious consequences. A 42-year-old male patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: NA and used Metformine (dosage: Unk) starting NS. After starting Metformine the patient began experiencing various side effects, including: Suicide Attempt, Overdose, Toxicity To Various Agents, Lactic Acidosis, ShockAdditional drugs used concurrently:
  • Insulin (Unk)
  • Clarithromycin (Unk)
  • Domperidone (Unk)
  • Ibuprofen (Unk)
  • Buflomedil (Unk)
  • Tiaprofenic Acid (Unk)
The patient was hospitalized. Although Metformine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Suicide Attempt, may still occur.
Metformine Side Effect Report#9403754
Lactic Acidosis, Ventricular Tachycardia, Intentional Overdose, Suicide Attempt
This Lactic Acidosis problem was reported by a health professional from TR. A 17-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Metformine (dosage: 75 Pills Of 1000mg). The following drugs were being taken at the same time:
  • Rupatadine (20 Pills Of 10mg)
  • Amitriptyline (10 Mg/day)
When using Metformine, the patient experienced the following unwanted symptoms/side effects: Lactic Acidosis, Ventricular Tachycardia, Intentional Overdose, Suicide AttemptAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Lactic Acidosis, may become evident only after a product is in use by the general population.
Metformine Side Effect Report#9318861
Lactic Acidosis, Renal Failure, Multi-organ Failure
This Lactic Acidosis side effect was reported by a physician from NL. A 68-year-old male patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus.The patient was prescribed Metformine Tablet 1000mg (drug dosage: 3 Times A Day One Piece), which was initiated on 2011. Concurrently used drugs:
  • Acenocoumarol Tablet 1mg (Va)
  • Slow K Tablet Mga 600mg (1dd1)
  • Lanoxin Tablet 0,25mg (1dd1)
  • Furosemide Tablet 40mg (2dd1)
  • Losartan Tablet Fo 100mg (1dd1)
  • Colchicine Tablet 0,5mg (3dd1)
  • Simvastatine Tablet 40mg (1dd1)
  • Spironolacton Tablet 25mg (1dd1)
.After starting to take Metformine Tablet 1000mg the consumer reported adverse symptoms, such as: Lactic Acidosis, Renal Failure, Multi-organ FailureThese side effects may potentially be related to Metformine Tablet 1000mg. The patient was hospitalized.
Metformine Side Effect Report#9314209
Lactic Acidosis, Renal Failure Acute, Respiratory Distress, Hypoglycaemia, Oliguria, Hypothermia, Vomiting, Tachycardia
This is a report of a 70-year-old female patient (weight: NA) from FR, suffering from the following health symptoms/conditions: type 2 diabetes mellitus, who was treated with Metformine (dosage: 3000 Mg/day, start time: NS), combined with:
  • Indapamide
  • Ketoprofen
  • Metformin (metformin)
  • Acetaminophen (acetaminophen)
  • Morphine
and developed a serious reaction and side effect(s): Lactic Acidosis, Renal Failure Acute, Respiratory Distress, Hypoglycaemia, Oliguria, Hypothermia, Vomiting, Tachycardia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metformine treatment in female patients, resulting in Lactic Acidosis side effect. The patient was hospitalized.
Metformine Side Effect Report#9249249
Angioedema
This report suggests a potential Metformine Tablet 500mg Angioedema side effect(s) that can have serious consequences. A 61-year-old female patient (weight: NA) from NL was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus and used Metformine Tablet 500mg (dosage: 1000 Milligram Daily; Twice Daily One Piece, Extra Info: 2x 500 Mg) starting 1990. After starting Metformine Tablet 500mg the patient began experiencing various side effects, including: AngioedemaAdditional drugs used concurrently:
  • Hydrochloorthiazide Tablet 12,5mg (12.5 Milligram Daily; Once Daily One Piece, Extra Info: 12.5 Mg)
  • Metoprolol Tablet 50mg (50 Milligram Daily; Once Daily One Piece)
  • Symbicort Turbuhaler Inhalpdr 100/6mcg/do 120do (2 Dosage Forms Daily; 2 Times A Day 1 Piece (s))
Although Metformine Tablet 500mg demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Angioedema, may still occur.
Metformine Side Effect Report#9166999
Metabolic Acidosis, Malaise, Fall, Dehydration
This Metabolic Acidosis problem was reported by a health professional from FR. A 80-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Dec 22, 2004 this consumer started treatment with Metformine (dosage: 850 Milligram Daily;). The following drugs were being taken at the same time:
  • Ramipril (5 Milligram Daily;)
  • Bisoprolol (10 Milligram Daily;)
  • Depamide 300 Mg (900 Milligram Daily;)
When using Metformine, the patient experienced the following unwanted symptoms/side effects: Metabolic Acidosis, Malaise, Fall, DehydrationThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Metabolic Acidosis, may become evident only after a product is in use by the general population.
Metformine Side Effect Report#9166256
Oedema
This Oedema side effect was reported by a health professional from FR. A female patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus,rheumatoid arthritis.The patient was prescribed Metformine (drug dosage: 2 Dosage Forms Daily;), which was initiated on 201001. Concurrently used drugs:
  • Roactemra
  • Victoza (1.2 Milligram Daily;)
  • Farlutal
  • Furosemide (20 Milligram Daily;)
  • Gliclazide (60 Milligram Daily;)
  • Kerlone (20 Milligram Daily;)
  • Amlodipine (10 Milligram Daily;)
  • Allopurinol (100 Milligram Daily;)
.After starting to take Metformine the consumer reported adverse symptoms, such as: OedemaThese side effects may potentially be related to Metformine.
Metformine Side Effect Report#9165178
Hepatitis, Jaundice, Hepatic Necrosis, Hepatitis E, Hepatic Fibrosis, Hepatic Steatosis
This is a report of a 59-year-old male patient (weight: NA) from FR, suffering from the following health symptoms/conditions: type 2 diabetes mellitus,osteoarthritis,hypercholesterolaemia,phlebitis,dermatosis,hypertension,depression, who was treated with Metformine (dosage: 1.5 Gram Daily; Taken For 4 Years, start time:
Sep 09, 2010), combined with:
  • Piascledine (300 Milligram Daily; 1 Df=300 Mg)
  • Crestor (5 Milligram Daily; Taken For 4 Years At Least)
  • Previscan (25 Milligram Daily; Taken For At Least 4 Years)
  • Fucidine
  • Zofenopril (30 Milligram Daily; Taken For More Than 1 Year)
  • Moclamine (450 Milligram Daily;)
  • Dafalgan (4 Gram Daily; Taken For More Than 1 Year)
  • Zanidip (10 Milligram Daily; Taken For At Least 4 Years)
and developed a serious reaction and side effect(s): Hepatitis, Jaundice, Hepatic Necrosis, Hepatitis E, Hepatic Fibrosis, Hepatic Steatosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metformine treatment in male patients, resulting in Hepatitis side effect. The patient was hospitalized.
Metformine Side Effect Report#9140129
Poisoning, Completed Suicide
This report suggests a potential Metformine Poisoning side effect(s) that can have serious consequences. A 53-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Metformine (dosage: NA) starting NS. After starting Metformine the patient began experiencing various side effects, including: Poisoning, Completed SuicideAdditional drugs used concurrently:
  • Verapamil
Although Metformine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Poisoning, may still occur.
Metformine Side Effect Report#9014624
Fatigue, Diarrhoea
This Fatigue problem was reported by a consumer or non-health professional from NL. A 46-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: diabetes mellitus. On 201112 this consumer started treatment with Metformine (dosage: NA). The following drugs were being taken at the same time:
  • Ezetrol Tablet 10mg
When using Metformine, the patient experienced the following unwanted symptoms/side effects: Fatigue, DiarrhoeaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Fatigue, may become evident only after a product is in use by the general population.
Metformine Side Effect Report#8939899
Gout
This Gout side effect was reported by a consumer or non-health professional from NL. A 85-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Metformine (drug dosage: 500 Mg, Bid), which was initiated on 2010. Concurrently used drugs:
  • Hydrochloorthiazide (25 Mg, Qod)
  • Ofloxacin (200 Mg, Qd)
  • Carbasalate Calcium (100 Mg, Qd)
  • Enalapril (10 Mg, Bid)
  • Omeprazol (20 Mg, Qd)
  • Isosorbide Mononitrate (30 Mg, Qd)
.After starting to take Metformine the consumer reported adverse symptoms, such as: GoutThese side effects may potentially be related to Metformine.
Metformine Side Effect Report#8924071
Lactic Acidosis, Renal Failure, Gastroenteritis, Dialysis
This is a report of a 53-year-old female patient (weight: NA) from NL, suffering from the following health symptoms/conditions: diabetes mellitus,vomiting, who was treated with Metformine Tablet 1000mg (dosage: NA, start time:
Oct 15, 2012), combined with:
  • Domperidon Zetpil 60mg
  • Gliclazide Tablet Mga 80mg
  • Hydrochloorthiazide Tablet 12,5mg
  • Irbesartan Tablet 150mg
  • Simvastatine Tablet 40mg
  • Lansoprazol Capsule Mga 30mg
  • Paracetamol Tablet 500mg
and developed a serious reaction and side effect(s): Lactic Acidosis, Renal Failure, Gastroenteritis, Dialysis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metformine Tablet 1000mg treatment in female patients, resulting in Lactic Acidosis side effect.
Metformine Side Effect Report#8916036
Gout
This report suggests a potential Metformine Gout side effect(s) that can have serious consequences. A male patient (weight: NA) from NL was diagnosed with the following symptoms/conditions: NA and used Metformine (dosage: NA) starting 2010. After starting Metformine the patient began experiencing various side effects, including: GoutAdditional drugs used concurrently:
  • Hydrochlorothiazide
  • Ofloxacine
  • Carbasalate Calcium
  • Enalapril
  • Omeprazol
  • Isosorbide Mononitrate
Although Metformine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Gout, may still occur.
Metformine Side Effect Report#8820798
Renal Failure Acute, Overdose, Blood Pressure Decreased, Renal Tubular Necrosis
This Renal Failure Acute problem was reported by a physician from NL. A male patient (weight: NA) was diagnosed with the following symptoms/conditions: type 2 diabetes mellitus,hypertension. On NS this consumer started treatment with Metformine (dosage: 20 Dosage Forms Daily; 20tabletsx500mg). The following drugs were being taken at the same time:
  • Olmetec (olmesartan Medoxomil) (14 Dosage Forms Daily; 14 Tab. X10mg)
  • Simvastatine Tablet 10mg (10 Mg)
When using Metformine, the patient experienced the following unwanted symptoms/side effects: Renal Failure Acute, Overdose, Blood Pressure Decreased, Renal Tubular NecrosisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Renal Failure Acute, may become evident only after a product is in use by the general population.
Metformine Side Effect Report#8414352-9
Petechiae, Ecchymosis, Skin Reaction, Conjunctival Haemorrhage
This Petechiae side effect was reported by a physician from Portugal. A female patient (weight:NA) experienced the following symptoms/conditions: type 2 diabetes mellitus,hypercholesterolaemia,depression,myasthenia gravis.The patient was prescribed Metformine Hydrochlorde (drug dosage: 1 Anz), which was initiated on
Feb 17, 2012. Concurrently used drugs:
  • Rosuvastatin (5 Mg)
  • Sertraline Hydrochloride (100 Mg)
  • Pyridostigmine Bromide (240 Mg)
  • Prednisolone (30 Mg)
  • Pradaxa (220 Mg)
  • Pantoprazole Sodium Sesquihydrate (40 Mg)
  • Glyburide (1 Anz)
  • Indapamide (1.5 Mg)
.After starting to take Metformine Hydrochlorde the consumer reported adverse symptoms, such as: Petechiae, Ecchymosis, Skin Reaction, Conjunctival HaemorrhageThese side effects may potentially be related to Metformine Hydrochlorde.
Metformine Side Effect Report#8287040-X
Petechiae, Conjunctival Haemorrhage, Skin Reaction, Ecchymosis
This is a report of a female patient (weight: NA) from Portugal, suffering from the following health symptoms/conditions: type 2 diabetes mellitus,hypertension,atrial fibrillation,myasthenia gravis, who was treated with Metformine Hydrochlorde (dosage: 1 Anz, start time:
Feb 17, 2012), combined with:
  • Diltiazem Hydrochloride (60 Mg)
  • Pradaxa (220 Mg)
  • Pyridostigmine Bromide (240 Mg)
  • Lisinopril (20 Mg)
  • Sertraline Hydrochloride (100 Mg)
  • Glyburide (1 Anz)
  • Pantoprazole Sodium Sesquihydrate (40 Mg)
  • Rosuvastatin Calcium (5 Mg)
and developed a serious reaction and side effect(s): Petechiae, Conjunctival Haemorrhage, Skin Reaction, Ecchymosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Metformine Hydrochlorde treatment in female patients, resulting in Petechiae side effect.


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The appearance of Metformine on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Metformine Side Effects for Women?

Women Side EffectsReports
Lactic Acidosis 4
Malaise 3
Renal Failure 3
Conjunctival Haemorrhage 2
Ecchymosis 2
Hepatic Failure 2
Hypoglycaemia 2
Metabolic Acidosis 2
Nausea 2
Petechiae 2

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Why Your Notes are Important

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  • Log Form

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    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Metformine reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    More About Metformine

    Side Effects reported to FDA: 35

    Metformine safety alerts: No

    Reported deaths: 2

    Reported hospitalizations: 13

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