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Diarrhea (16)
Headache (7)
Dizziness (6)
Toes Hurt (4)
Flatulence (3)
Autoimmune Neutropenia (3)
Dizzy (1)
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Metformine Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Petechiae, Ecchymosis, Skin Reaction, Conjunctival Haemorrhage (8414352-9)
on May 28, 2012 Female from PORTUGAL , weighting 176.4 lb, was diagnosed with
  • type 2 diabetes mellitus
  • hypercholesterolaemia
  • depression
  • myasthenia gravis
and was treated with Metformine Hydrochlorde. Directly after, patient experienced the unwanted or unexpected Metformine side effects: petechiae, ecchymosis, skin reaction, conjunctival haemorrhage. Metformine Hydrochlorde dosage: 1 Anz.
Associated medications used:
  • Rosuvastatin (5 Mg)
  • Sertraline Hydrochloride (100 Mg)
  • Pyridostigmine Bromide (240 Mg)
  • Prednisolone (30 Mg)
  • Pradaxa (220 Mg)
  • Pantoprazole Sodium Sesquihydrate (40 Mg)
  • Glyburide (1 Anz)
  • Indapamide (1.5 Mg)


Petechiae, Conjunctival Haemorrhage, Skin Reaction, Ecchymosis (8287040-X)
Patient was taking Metformine Hydrochlorde. Patient felt the following Metformine side effects: petechiae, conjunctival haemorrhage, skin reaction, ecchymosis on Apr 09, 2012 from PORTUGAL Additional patient health information: Female , weighting 176.4 lb, was diagnosed with
  • type 2 diabetes mellitus
  • hypertension
  • atrial fibrillation
  • myasthenia gravis
and. Metformine Hydrochlorde dosage: 1 Anz.
Multiple prescriptions taken:
  • Diltiazem Hydrochloride (60 Mg)
  • Pradaxa (220 Mg)
  • Pyridostigmine Bromide (240 Mg)
  • Lisinopril (20 Mg)
  • Sertraline Hydrochloride (100 Mg)
  • Glyburide (1 Anz)
  • Pantoprazole Sodium Sesquihydrate (40 Mg)
  • Rosuvastatin Calcium (5 Mg)


Organising Pneumonia, Lung Disorder (7644019-6)
Adverse event was reported on Jul 26, 2011 by a Male taking Metformine ^merck^ (Dosage: Unk) . Location: NETHERLANDS , 64 years of age, After Metformine was administered, patient encountered several Metformine side effects: organising pneumonia, lung disorder.
Multiple concurrent drugs taken:
  • Omeprazole
  • Glimepiride
  • Lipitor (20 Mg, 1x/day)
  • Fluvoxamine Maleate
  • Diovan (Unk)
  • Acetylsalicylic Acid


Diarrhoea, Nausea, Hiccups (7459534-8)
on Apr 27, 2011 Male from FRANCE , 63 years of age, weighting 216.1 lb, was treated with Metformine. Directly after, patient experienced the unwanted or unexpected Metformine side effects: diarrhoea, nausea, hiccups. Metformine dosage: N/A.
Associated medications used:
  • Victoza (Unk)



B-cell Lymphoma (7394684-6)
on Mar 28, 2011 Male from UNITED STATES , 47 years of age, was treated with Metformine. Patient felt the following Metformine side effects: b-cell lymphoma. Metformine dosage: Unk.
Multiple prescriptions taken:
  • Ramipril (Unk)
  • Filgrastim (Unk)
  • Intelence (Unk)
  • Ribavirin (200 Mg, Q4h)
  • Isentress (Unk)
  • Peginterferon Alfa-2a (168 A?g, Qwk)
  • Lederfoline (Unk)
  • Crestor


Pancreatitis, Weight Decreased, Renal Failure Acute (7371453-4)
Patient was taking Metformine. After Metformine was administered, patient encountered several Metformine side effects: pancreatitis, weight decreased, renal failure acute on Mar 16, 2011 from FRANCE Additional patient health information: Male , 43 years of age, weighting 262.4 lb, . Metformine dosage: 2 G, Qd.
Multiple concurrent drugs taken:
  • Byetta ((10x2))
  • Victoza (Unk)


Tachycardia Paroxysmal, Nausea (7366022-6)
Adverse event was reported on Mar 08, 2011 by a Female taking Metformine (Dosage: N/A) was diagnosed with
  • type 2 diabetes mellitus
and. Location: FRANCE , 75 years of age, weighting 198.4 lb, Directly after, patient experienced the unwanted or unexpected Metformine side effects: tachycardia paroxysmal, nausea. Patient was hospitalized.

Nausea, Tachycardia Paroxysmal (7366021-4)
on Mar 08, 2011 Female from FRANCE , 75 years of age, weighting 198.4 lb, was diagnosed with
  • type 2 diabetes mellitus
and was treated with Metformine. Patient felt the following Metformine side effects: nausea, tachycardia paroxysmal. Metformine dosage: N/A. Patient was hospitalized.

Cytolytic Hepatitis, Hepatic Failure, Cholestasis, Jaundice (7281379-2)
on Feb 04, 2011 Female from FRANCE , 76 years of age, was treated with Metformine. After Metformine was administered, patient encountered several Metformine side effects: cytolytic hepatitis, hepatic failure, cholestasis, jaundice. Metformine dosage: N/A.
Multiple concurrent drugs taken:
  • Nidrel
  • Tenormin
  • Aspirin
  • Lipanthyl Tablets
  • Allopurinol
  • Amarel
Patient was hospitalized.

Hypoglycaemia, Malaise (5733166-1)
Patient was taking Metformine. Directly after, patient experienced the unwanted or unexpected Metformine side effects: hypoglycaemia, malaise on Apr 22, 2008 from FRANCE Additional patient health information: Female , 83 years of age, was diagnosed with
  • diabetes mellitus
and. Metformine dosage: 1 Dr, Daily, Oral.
Associated medications used:
  • Glibenclamide (no Pref. Name) (1 Df, Daily, Oral)
  • Enalapril Merck (enalapril Maleate)
  • Diltiazem (diltiazem Hydrochloride)
  • Hydrochlorothiazide
Patient was hospitalized.

Blood Creatine Phosphokinase Increased, Neck Pain (5224907-0)
Adverse event was reported on Jan 12, 2007 by a Male taking Metformine Rpg 850 Mg Comprime Pellicule (metformin Hydrochloride) Unk (Dosage: 1700 Md, Qd, Unk) . Location: FRANCE , 68 years of age, Patient felt the following Metformine side effects: blood creatine phosphokinase increased, neck pain.
Multiple prescriptions taken:
  • Tahor
Patient was hospitalized.

Atrial Fibrillation, Malaise, Orthostatic Hypotension (4806735-0)
on Sep 30, 2005 Female from FRANCE , 84 years of age, was diagnosed with
  • diabetes mellitus
and was treated with Metformine. After Metformine was administered, patient encountered several Metformine side effects: atrial fibrillation, malaise, orthostatic hypotension. Metformine dosage: 1700 Mg (850 Mg, 2 In 1 D), Oral.
Multiple concurrent drugs taken:
  • Nootropyl (piracetam) (3 Dosage Forms (1 Dosage , 1 D), Oral)
  • Aricept (1 Dosage Forms (1 Dosage Forms, 1 1in 1 D), Oral)
  • Fenofibrate
  • Orocal D3 (buccal Tablet)
  • Fosamax
Patient was hospitalized.

Metformine Health Episodes

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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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