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Methycobal Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 82 

Interstitial Lung Disease, Dyspnoea (7933739-1)
on Nov 21, 2011 Male from JAPAN , 63 years of age, weighting 122.6 lb, was treated with Methycobal. Directly after, patient experienced the unwanted or unexpected Methycobal side effects: interstitial lung disease, dyspnoea. Methycobal dosage: Unk.
Associated medications used:
  • Seltouch (Unk)
  • Etodolac (Unk)
  • Zestak (Unk)
  • Triazolam (Unk)
  • Lyrica (50mg/day)
  • Rebamipide (Unk)
  • Myonal (Unk)
  • Lyrica (25 Mg/day)
Patient was hospitalized.

Interstitial Lung Disease (7932650-X)
Patient was taking Methycobal. Patient felt the following Methycobal side effects: interstitial lung disease on Nov 14, 2011 from JAPAN Additional patient health information: Female , 89 years of age, was diagnosed with
  • diabetes mellitus
  • hypertension
and. Methycobal dosage: N/A.
Multiple prescriptions taken:
  • Lasix
  • Magnesium Sulfate
  • Ketoprofen
  • Aspirin
  • Irbesartan


Metastases To Bone, Adverse Reaction, Acute Prerenal Failure, Off Label Use, Nephrotic Syndrome, Neoplasm Progression (7918373-1)
Adverse event was reported on Nov 14, 2011 by a Male taking Methycobal (Dosage: 500 Ug, Unk) was diagnosed with
  • prophylaxis
  • hypertension
  • pleural mesothelioma malignant
and. Location: JAPAN , weighting 176.4 lb, After Methycobal was administered, patient encountered several Methycobal side effects: metastases to bone, adverse reaction, acute prerenal failure, off label use, nephrotic syndrome, neoplasm progression.
Multiple concurrent drugs taken:
  • Amlodipine (5 Mg, Qd)
  • Alimta (750 Mg, Every 3 Weeks)
  • Gemzar (Unk)
  • Amlodipine (10 Mg, Qd)
  • Panvitan (1 G, Qd)
  • Calblock (8 Mg, Qd)
  • Cisplatin (100 Mg, Every 3 Weeks)
Patient was hospitalized.

Osteomyelitis (7918014-3)
on Nov 09, 2011 Female from JAPAN , 64 years of age, was diagnosed with
  • spinal column stenosis
  • osteoporosis
and was treated with Methycobal. Directly after, patient experienced the unwanted or unexpected Methycobal side effects: osteomyelitis. Methycobal dosage: N/A.
Associated medications used:
  • Fosamax
  • Anplag



Intraocular Pressure Increased (7916947-5)
on Oct 28, 2011 Female from JAPAN , 72 years of age, weighting 130.1 lb, was treated with Methycobal (mecobalamin). Patient felt the following Methycobal side effects: intraocular pressure increased. Methycobal (mecobalamin) dosage: N/A.
Multiple prescriptions taken:
  • Bronuck (bromfenac Sodium)
  • Carnaculin (pancreas Extract)
  • Adona (carbazochrome Sodium Sulfonate)
  • Rinderon A (betamethasone Sodium Phosphate, Neomycin Sulfate)
  • Mikelan (carteolol Hydrochloride)
  • Lomefloxacin Hydrochloride (lomefloxacin Hydrochloride)
  • Macugen (0.3 Mg Into The Left Eye, Introcular)
  • Xalatan


Hiccups, Urine Output Decreased (7915952-2)
Patient was taking Methycobal. After Methycobal was administered, patient encountered several Methycobal side effects: hiccups, urine output decreased on Nov 09, 2011 from JAPAN Additional patient health information: Male , 86 years of age, . Methycobal dosage: N/A.
Multiple concurrent drugs taken:
  • Emend
  • Fluorouracil
  • Mucosta
  • Adalat
  • Emend
  • Granisetron Hydrochloride
  • Lactec
  • Cisplatin


Dysarthria, Muscular Weakness, Altered State Of Consciousness, Gait Disturbance, Encephalopathy (7904701-X)
Adverse event was reported on Nov 01, 2011 by a Female taking Methycobal (Dosage: N/A) . Location: JAPAN , 83 years of age, Directly after, patient experienced the unwanted or unexpected Methycobal side effects: dysarthria, muscular weakness, altered state of consciousness, gait disturbance, encephalopathy.
Associated medications used:
  • Valtrex
  • Aspirin
  • Omeprazole


Hypokalaemia, Hyponatraemia, Pneumocystis Jiroveci Pneumonia, Febrile Neutropenia, Renal Disorder (7892749-3)
on Oct 18, 2011 Male from JAPAN , 59 years of age, was diagnosed with
  • lymphoma
  • pneumocystis jiroveci pneumonia
  • diffuse large b-cell lymphoma
and was treated with Methycobal. Patient felt the following Methycobal side effects: hypokalaemia, hyponatraemia, pneumocystis jiroveci pneumonia, febrile neutropenia, renal disorder. Methycobal dosage: N/A.
Multiple prescriptions taken:
  • Baktar
  • Doxorubicin Hcl
  • Methylprednisolone
  • Neuquinon
  • Mucosta
  • Rabeprazole Sodium
  • Methylprednisolone
  • Vincristine Sulfate
Patient was hospitalized.

Cognitive Disorder, Vision Blurred (7830572-6)
on Oct 17, 2011 Female from JAPAN , 52 years of age, was treated with Methycobal. After Methycobal was administered, patient encountered several Methycobal side effects: cognitive disorder, vision blurred. Methycobal dosage: Unk.
Multiple concurrent drugs taken:
  • Loxonin (Unk)
  • Lyrica (75 Mg Daily)
  • Depas (Unk)


Interstitial Lung Disease (7791689-8)
Patient was taking Methycobal. Directly after, patient experienced the unwanted or unexpected Methycobal side effects: interstitial lung disease on Sep 26, 2011 from JAPAN Additional patient health information: Female , weighting 132.3 lb, . Methycobal dosage: N/A.
Associated medications used:
  • Alendronate Sodium
  • Doxorubicin Hcl (Course 1)
  • Omeprazole
  • Lipitor
  • Juvela N
  • Clonazepam
  • Prednisolone
  • Norvasc
Patient was hospitalized and became disabled.

Malaise, Blood Pressure Decreased, Dehydration, Restlessness, Bone Marrow Failure, Interstitial Lung Disease, Anuria, Pancytopenia, Deep Vein Thrombosis (7775082-X)
Adverse event was reported on Sep 19, 2011 by a Female taking Methycobal (Dosage: N/A) was diagnosed with
  • neuropathy peripheral
  • interstitial lung disease
  • disseminated intravascular coagulation
and. Location: JAPAN , weighting 125.7 lb, Patient felt the following Methycobal side effects: malaise, blood pressure decreased, dehydration, restlessness, bone marrow failure, interstitial lung disease, anuria, pancytopenia, deep vein thrombosis.
Multiple prescriptions taken:
  • Bactrim
  • Futhan
  • Prednisolone
  • Doxil
  • Bactrim
  • Solu-medrol
  • Solu-medrol
  • Elaspol
Patient was hospitalized.

Renal Failure Acute (7771300-2)
on Sep 14, 2011 Male from JAPAN , 79 years of age, weighting 92.59 lb, was diagnosed with
  • hypovitaminosis
  • oedema
  • atrial fibrillation
and was treated with Methycobal. After Methycobal was administered, patient encountered several Methycobal side effects: renal failure acute. Methycobal dosage: N/A.
Multiple concurrent drugs taken:
  • Lasix
  • Warfarin Potassium
  • Warfarin Potassium
  • Allopurinol
  • Ferrous Citrate
  • Carvedilol
  • Depas
  • Januvia
Patient was hospitalized and became disabled.

Urinary Incontinence, Faecal Incontinence (7747632-0)
on Sep 09, 2011 Male from JAPAN , 45 years of age, was diagnosed with
  • hypoaesthesia
  • back pain
  • pain in extremity
and was treated with Methycobal. Directly after, patient experienced the unwanted or unexpected Methycobal side effects: urinary incontinence, faecal incontinence. Methycobal dosage: 500 Mg, 2x/day.

Cancer Pain, Insomnia, Cough, Metastases To Lung (7742728-1)
Patient was taking Methycobal. Patient felt the following Methycobal side effects: cancer pain, insomnia, cough, metastases to lung on Aug 29, 2011 from JAPAN Additional patient health information: Male , 64 years of age, . Methycobal dosage: N/A.
Multiple prescriptions taken:
  • Dextromethorphan Hydrobromide
  • Magnesium Sulfate
  • Decadron
  • Urief
  • Astomin
  • Remeron


Pleural Effusion, Atelectasis, Pneumonia (7736448-7)
Adverse event was reported on Sep 04, 2011 by a Female taking Methycobal (Dosage: N/A) . Location: JAPAN , 70 years of age, After Methycobal was administered, patient encountered several Methycobal side effects: pleural effusion, atelectasis, pneumonia.
Multiple concurrent drugs taken:
  • Mucosolvan
  • Etanercept
  • Lipitor
  • Marzulene-s
  • Famotidine
  • Voltaren (Voltaren Tape And Voltaren Suppo)
  • Ibruprofen
  • Orencia
Patient was hospitalized.

Altered State Of Consciousness, Convulsion (7735747-2)
on Jul 04, 2011 Female from JAPAN , 40 years of age, was treated with Methycobal. Directly after, patient experienced the unwanted or unexpected Methycobal side effects: altered state of consciousness, convulsion. Methycobal dosage: N/A.
Associated medications used:
  • Imuran
  • Alosenn
  • Avonex


Cardiovascular Disorder (7727298-6)
on Aug 30, 2011 Male from JAPAN , 57 years of age, was treated with Methycobal. Patient felt the following Methycobal side effects: cardiovascular disorder. Methycobal dosage: 100 Mg, Daily.
Multiple prescriptions taken:
  • Rize (Unk)
  • Celecoxib (200 Mg, Daily)
  • Vesicare (Unk)
  • Warfarin (3 Mg, Daily)
  • Lyrica (50 Mg, Daily)


Bladder Disorder, Anorectal Disorder (7724392-0)
Patient was taking Methycobal. After Methycobal was administered, patient encountered several Methycobal side effects: bladder disorder, anorectal disorder on Aug 29, 2011 from JAPAN Additional patient health information: Male , 45 years of age, was diagnosed with
  • back pain
and. Methycobal dosage: 1000 Ug Daily.
Multiple concurrent drugs taken:
  • Lyrica (150 Mg Daily)
  • Lyrica (75 Mg Daily)


Neoplasm Progression, Oedema Peripheral, Asthenia (7722485-5)
Adverse event was reported on Aug 29, 2011 by a Male taking Methycobal (Dosage: 500 Microg) . Location: JAPAN , 74 years of age, Directly after, patient experienced the unwanted or unexpected Methycobal side effects: neoplasm progression, oedema peripheral, asthenia.
Associated medications used:
  • Oxycontin (Unk)
  • Voltaren (25mg Daily)
  • Lyrica (75 Mg, 2x/day)
  • Ferrous Citrate (50mg Daily)
  • Lyrica (75 Mg, 1x/day)
  • Voltaren (50mg Daily)
  • Mucosta (100mg Daily)
  • Cinal (Unk)
Patient was hospitalized.

Hepatic Function Abnormal (7706502-4)
on Aug 19, 2011 Female from JAPAN , 68 years of age, weighting 109.6 lb, was treated with Methycobal. Patient felt the following Methycobal side effects: hepatic function abnormal. Methycobal dosage: 500 Ug, 3x/day.
Multiple prescriptions taken:
  • Acetaminophen (400 Mg, 3x/day)
  • Lyrica (25 Mg, 1x/day)
  • Amoxapine (25 Mg, 1x/day)
  • Loxonin (Unk)
  • Lyrica (75 Mg, 2x/day)
  • Valtrex (Unk)
  • Juvela (100 Mg, Unk)
  • Magnesium Sulfate (500 Mg, 2x/day)
Patient was hospitalized.

Orthostatic Hypotension (7692022-2)
on Aug 09, 2011 Male from JAPAN , 66 years of age, weighting 121.3 lb, was diagnosed with
  • neuropathy peripheral
  • intestinal obstruction
  • hypertension
  • dry skin prophylaxis
and was treated with Methycobal. After Methycobal was administered, patient encountered several Methycobal side effects: orthostatic hypotension. Methycobal dosage: N/A.
Multiple concurrent drugs taken:
  • Daiken-chyuto
  • Amlodipine
  • Azunol
  • Kobalnon
  • Keratinamin
  • Tamsulosin Hcl
  • Alosenn
  • Incarbon
Patient was hospitalized.

Fall, Altered State Of Consciousness (7691008-1)
Patient was taking Methycobal. Directly after, patient experienced the unwanted or unexpected Methycobal side effects: fall, altered state of consciousness on Aug 17, 2011 from JAPAN Additional patient health information: Male , 74 years of age, . Methycobal dosage: 500 Mg Daily.
Associated medications used:
  • Cytotec (200 Microg Daily)
  • Plavix (75 Mg Daily)
  • Amlodipine (5 Mg Daily)
  • Sigmart (5 Mg Daily)
  • Carvedilol (10 Mg Daily)
  • Voltaren (25 Mg Daily)
  • Lyrica (150 Mg Daily)
  • Aspirin (100 Mg Daily)


Blood Creatinine Increased (7675125-8)
Adverse event was reported on Aug 03, 2011 by a Male taking Methycobal (Dosage: N/A) . Location: JAPAN , 67 years of age, Patient felt the following Methycobal side effects: blood creatinine increased.
Multiple prescriptions taken:
  • Amaryl
  • Pletal
  • Urso 250
  • Aspirin
  • Candesartan Cilexetil
  • Januvia
  • Actos
  • Metformin Hcl


Interstitial Lung Disease, Dyspnoea Exertional, Dizziness, Respiratory Failure (7655738-X)
on Jul 26, 2011 Female from JAPAN , 88 years of age, was treated with Methycobal (mecobalamin). After Methycobal was administered, patient encountered several Methycobal side effects: interstitial lung disease, dyspnoea exertional, dizziness, respiratory failure. Methycobal (mecobalamin) dosage: N/A.
Multiple concurrent drugs taken:
  • Crestor
  • Etodolac
  • Risedronate Sodium (17.5mg Once Weekly, Oral)
  • Isosorbide Mononitrate
  • Onealfa (alfacalcidol)
  • Sennoside
  • Mucosta (rebamipide)
  • Tenormin


Thrombocytopenia, Rash, Pyrexia, Platelet Count Decreased, Salivary Hypersecretion, Viith Nerve Paralysis, Vomiting, Dizziness (7654118-0)
on Jul 27, 2011 Male from JAPAN , 71 years of age, was treated with Methycobal. Directly after, patient experienced the unwanted or unexpected Methycobal side effects: thrombocytopenia, rash, pyrexia, platelet count decreased, salivary hypersecretion, viith nerve paralysis, vomiting, dizziness. Methycobal dosage: N/A.
Associated medications used:
  • Tegretol (800 Mg, Daily)
  • Adenosine
  • Mucosta
  • Saxizon
  • Lyrica
  • Paxil
  • Tegretol (1200 Mg, Daily)
  • Dogmatyl
Patient was hospitalized.

Showing 1-25 of 82 

Methycobal Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Methycobal Information

More About Methycobal

Side Effects reported to FDA: 82. View Methycobal Adverse Reports

Methycobal safety alerts: No

Reported deaths: 12

Reported hospitalizations: 39

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