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Dizziness (42)
Potassium (29)
Am Experiencing Hair Loss (23)
Back Pain (22)
Smelly Gas (14)
Blood Sugar (13)
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Miralax Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 424 

Dehydration, Hypersomnia (8264912-3)
on Dec 08, 2011 Female from UNITED STATES , 63 years of age, weighting 130.0 lb, was diagnosed with
  • constipation
and was treated with Miralax. Directly after, patient experienced the unwanted or unexpected Miralax side effects: dehydration, hypersomnia. Miralax dosage: 17 Gm;once Po.

Heart Rate Irregular, Product Quality Issue, Constipation, Dyspnoea (8259807-5)
Patient was taking Miralax. Patient felt the following Miralax side effects: heart rate irregular, product quality issue, constipation, dyspnoea on Mar 28, 2012 from UNITED STATES Additional patient health information: Male , 93 years of age, weighting 180.8 lb, . Miralax dosage: N/A.
Multiple prescriptions taken:
  • Magnesium Hydroxide Tab (2-3 Caps Full/ Day)
  • Phillips' Milk Of Magnesia Liquid Original
Patient was hospitalized.

Cardiac Arrest (8258618-4)
Adverse event was reported on Apr 03, 2012 by a Male taking Miralax (Dosage: N/A) . Location: UNITED STATES , 55 years of age, weighting 158.0 lb, After Miralax was administered, patient encountered several Miralax side effects: cardiac arrest.
Multiple concurrent drugs taken:
  • Oxycodone Hcl
  • Aldactone
  • Compazine
  • Rifaximin
  • Lactulose
  • Siliphos (sylbin-phosphatidylcholine Complex (666mg, Tid, Po)
  • Lasix


Application Site Rash, Application Site Vesicles, Blister (8244662-X)
on Feb 16, 2012 Female from UNITED STATES , 47 years of age, was diagnosed with
  • laxative supportive care
  • myelitis
  • breakthrough pain
and was treated with Miralax /00754501/. Directly after, patient experienced the unwanted or unexpected Miralax side effects: application site rash, application site vesicles, blister. Miralax /00754501/ dosage: N/A.
Associated medications used:
  • Fentanyl-100 (Q72hr)
  • Morphine
  • Fentanyl-100 (Q72hr)
  • Fentanyl-100 (Q72hr)



Pyrexia, Tumour Necrosis, Insulinoma, Blood Glucose Decreased, Abscess (8234928-1)
on Jan 17, 2011 Female from UNITED STATES , 52 years of age, weighting 255.7 lb, was treated with Miralax. Patient felt the following Miralax side effects: pyrexia, tumour necrosis, insulinoma, blood glucose decreased, abscess. Miralax dosage: N/A.
Multiple prescriptions taken:
  • Afinitor (10mg Daily, Oral)
  • Synthroid
  • Octreotide Acetate
  • Multi-vit (vitamins Nos)


Urticaria, Pruritus, Rash, Pallor, Paraesthesia, Tremor, Abdominal Discomfort, Dyspnoea, Blood Pressure Decreased (8234189-3)
Patient was taking Miralax. After Miralax was administered, patient encountered several Miralax side effects: urticaria, pruritus, rash, pallor, paraesthesia, tremor, abdominal discomfort, dyspnoea, blood pressure decreased on Mar 05, 2012 from UNITED STATES Additional patient health information: Female , 55 years of age, weighting 159.0 lb, was diagnosed with
  • constipation
and. Miralax dosage: ; Po; 17 Gm; Po. Patient was hospitalized.

Pain In Extremity (8225395-2)
Adverse event was reported on Mar 07, 2011 by a Male taking Miralax (Dosage: N/A) . Location: UNITED STATES , 23 years of age, Directly after, patient experienced the unwanted or unexpected Miralax side effects: pain in extremity.
Associated medications used:
  • Afinitor (10 Mg, Oral)
  • Risperdal
  • Lexapro
  • Ditropan
  • Carbatrol (carbazmazepine)


Impaired Healing (8222809-9)
on Mar 09, 2012 Female from UNITED STATES , weighting 96.56 lb, was treated with Miralax. Patient felt the following Miralax side effects: impaired healing. Miralax dosage: N/A.
Multiple prescriptions taken:
  • Remicade
  • Mesalamine
Patient was hospitalized.

Muscular Weakness, Lymphoedema (8216750-5)
on Mar 05, 2012 Male from UNITED STATES , child 5 years of age, weighting 28.66 lb, was diagnosed with
  • constipation
and was treated with Miralax. After Miralax was administered, patient encountered several Miralax side effects: muscular weakness, lymphoedema. Miralax dosage: Unk.
Multiple concurrent drugs taken:
  • Phenol (Unk)
  • Baclofen (5 Mg, Unk)
  • Botulinum Toxin Type A (Unk)
Patient was hospitalized.

Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased (8211462-6)
Patient was taking Miralax. Directly after, patient experienced the unwanted or unexpected Miralax side effects: aspartate aminotransferase increased, alanine aminotransferase increased on Nov 08, 2011 from UNITED STATES Additional patient health information: Male , 42 years of age, weighting 231.5 lb, . Miralax dosage: N/A.
Associated medications used:
  • Oxycontin
  • Celexa
  • Crizotinib (antineoplastic Agents) (250 Mg, 2 In 1 Day, Oral 200 Mg, 2 In 1 Day, Oral 150 Mg, 2 In 1 Day, Oral)
  • Crizotinib (antineoplastic Agents) (250 Mg, 2 In 1 Day, Oral 200 Mg, 2 In 1 Day, Oral 150 Mg, 2 In 1 Day, Oral)
  • Crizotinib (antineoplastic Agents) (250 Mg, 2 In 1 Day, Oral 200 Mg, 2 In 1 Day, Oral 150 Mg, 2 In 1 Day, Oral)
  • Crizotinib (antineoplastic Agents) (250 Mg, 2 In 1 Day, Oral 200 Mg, 2 In 1 Day, Oral 150 Mg, 2 In 1 Day, Oral)
  • Motrin (400 Mg, 3 In 1 Day, Oral)
  • Oxycodone Hcl


Lumbar Spinal Stenosis, Fall, Device Related Infection, Vertebral Foraminal Stenosis, Back Pain, Pain In Extremity, Haemoglobin Decreased, Condition Aggravated, Nausea (8200693-7)
Adverse event was reported on Feb 08, 2012 by a Male taking Miralax /00754501/ (macrogol) (Dosage: N/A) . Location: UNITED STATES , 63 years of age, weighting 280.0 lb, Patient felt the following Miralax side effects: lumbar spinal stenosis, fall, device related infection, vertebral foraminal stenosis, back pain, pain in extremity, haemoglobin decreased, condition aggravated, nausea.
Multiple prescriptions taken:
  • Dilaudid
  • Milk Of Magnesia Tab
  • Provenge (250 Ml, Single)
  • Tylenol /00020001/ (paracetamol)
  • Provenge (250 Ml, Single)
  • Benadryl
  • Phenergan /00033001/ (promethazine)
  • Ambien
Patient was hospitalized.

Respiratory Failure (8200082-5)
on Mar 08, 2012 Male from UNITED STATES , weighting 55.78 lb, was diagnosed with
  • constipation
  • anxiety
  • convulsion
and was treated with Miralax /00754501/. After Miralax was administered, patient encountered several Miralax side effects: respiratory failure. Miralax /00754501/ dosage: 17 G, As Req'd.
Multiple concurrent drugs taken:
  • Lorazepam (0.5 Mg, As Req'd)
  • Diastat (5 Mg, As Req'd)
  • Diphenhydramine Hcl (25 Mg, 1x/week)
  • Robinul
  • Idursulfase (12 Mg, 1x/week)
  • Keppra (200 Mg, 2x/day:bid)


Splenomegaly, Splenic Rupture, Hypotension, Dehydration, Vascular Pseudoaneurysm, Splenic Infarction, Ascites (8196615-8)
on Mar 02, 2012 Female from UNITED STATES , 74 years of age, weighting 149.0 lb, was treated with Miralax. Directly after, patient experienced the unwanted or unexpected Miralax side effects: splenomegaly, splenic rupture, hypotension, dehydration, vascular pseudoaneurysm, splenic infarction, ascites. Miralax dosage: 17 G, Qd. Patient was hospitalized.

Frustration, Scratch, Self Injurious Behaviour, Tic, Dysphemia, Vomiting, Crying, Anger, Screaming (8184697-9)
Patient was taking Miralax. Patient felt the following Miralax side effects: frustration, scratch, self injurious behaviour, tic, dysphemia, vomiting, crying, anger, screaming on Mar 05, 2012 from UNITED STATES Additional patient health information: Female , child 4 years of age, weighting 35.00 lb, was diagnosed with
  • faecaloma
  • constipation
and. Miralax dosage: 1/2 Capful.

Hypersensitivity, Hyperhidrosis, Retching, Dyspnoea, Musculoskeletal Stiffness, Dyskinesia, Tachycardia, Infusion Site Extravasation, Erythema (8178121-X)
Adverse event was reported on Dec 19, 2011 by a Female taking Miralax (macrogol) Powder (except [dpo]) (Dosage: N/A) . Location: UNITED STATES , 85 years of age, After Miralax was administered, patient encountered several Miralax side effects: hypersensitivity, hyperhidrosis, retching, dyspnoea, musculoskeletal stiffness, dyskinesia, tachycardia, infusion site extravasation, erythema.
Multiple concurrent drugs taken:
  • Sevelamer (sevelamer) Tablet
  • Synthroid (levothyroxine Sodium) Tablet
  • Vitamin B12
  • Toprol-xl
  • Depakene (valproate Sodium) Liquid
  • Ferrous Sulfate Tab
  • Feraheme (510 Mg, Single, Intravenous)
  • Folic Acid


Flank Pain, Haemoglobin Decreased, Red Blood Cell Count Decreased, Heart Rate Increased, Aspartate Aminotransferase Increased, White Blood Cell Count Increased, Pyrexia, Urinary Retention, Nephrolithiasis (8173547-2)
on Feb 21, 2012 Female from UNITED STATES , 29 years of age, weighting 166.9 lb, was treated with Miralax. Directly after, patient experienced the unwanted or unexpected Miralax side effects: flank pain, haemoglobin decreased, red blood cell count decreased, heart rate increased, aspartate aminotransferase increased, white blood cell count increased, pyrexia, urinary retention, nephrolithiasis. Miralax dosage: Unk Unk, Prn.
Associated medications used:
  • Ambien (10 Mg, Prn)
  • Effexor (37.5 Mg, Qd)
  • Naproxen (aleve)
Patient was hospitalized.

(8166821-7)
on Feb 23, 2012 Male from UNITED STATES , weighting 55.78 lb, was diagnosed with
  • constipation
  • salivary hypersecretion
  • anxiety
  • nervous system disorder
  • convulsion
  • mucopolysaccharidosis ii
and was treated with Miralax /00754501/. . Miralax /00754501/ dosage: 17 G, As Req'd.
Multiple prescriptions taken:
  • Robinul
  • Lorazepam (0.5 Mg, As Req'd)
  • Keppra (200 Mg, 2x/day:bid)
  • Diastat (5 Mg, As Req'd)
  • Idursulfase (12 Mg, 1x/week)
  • Diphenhydramine Hcl (25 Mg, 1x/week)


Product Quality Issue (8162483-3)
Patient was taking Miralax. After Miralax was administered, patient encountered several Miralax side effects: product quality issue on Feb 24, 2012 from UNITED STATES Additional patient health information: Male , 88 years of age, weighting 125.0 lb, was diagnosed with
  • constipation
and. Miralax dosage: N/A.

Palpitations (8145353-6)
Adverse event was reported on Feb 02, 2012 by a Male taking Miralax (Dosage: N/A) . Location: UNITED STATES , 84 years of age, weighting 140.0 lb, Directly after, patient experienced the unwanted or unexpected Miralax side effects: palpitations.
Associated medications used:
  • Stool Softner
  • Flaxseed Oil
  • Sinemet (25/100 Mg Tablet, Four Times Daily, Oral 50/200 Every Day At Night)
  • Sinemet (25/100 Mg, Half Tablet, Five Times Daily, Oral)
  • Apokyn (apomorphine Hydrochloride) (apomorphine Hydrochloride) (apomor (0.2 Ml In Morning, 0.3 Ml In Afternoon, Subcutaneous)
  • Sugar Free Cough Drops
  • Magnesium Phosphate
  • Aspirin


Femur Fracture, Osteoporosis, Gastric Ulcer, Pathological Fracture, Fracture Nonunion, Bone Marrow Oedema, Activities Of Daily Living Impaired, Gait Disturbance, Low Turnover Osteopathy (8131924-X)
on Jan 26, 2012 Female from UNITED STATES , 64 years of age, was treated with Miralax /00754501/ (macrogol). Patient felt the following Miralax side effects: femur fracture, osteoporosis, gastric ulcer, pathological fracture, fracture nonunion, bone marrow oedema, activities of daily living impaired, gait disturbance, low turnover osteopathy. Miralax /00754501/ (macrogol) dosage: N/A.
Multiple prescriptions taken:
  • Ergocalciferol
  • Multivitamins (ascorbic Acid, Ergocalciferol, Folic Acid, Nicotinamide
  • Metamucil /00091301/ (psyllium Hydrophilic Mucilloid)
  • Nexium
  • Erythromycin
  • Fluticasone /00972202/ (fluticasone Propionate)
  • Actonel (35 Mg Once Weekly, Oral)
  • Vitamin E /00110501/ (tocopherol)


Tic (8127899-X)
on Dec 07, 2011 Female from UNITED STATES , child 8 years of age, was treated with Miralax. After Miralax was administered, patient encountered several Miralax side effects: tic. Miralax dosage: N/A.
Multiple concurrent drugs taken:
  • Paxil (1ml Per Day)


Fall, Hip Fracture (8123655-7)
Patient was taking Miralax. Directly after, patient experienced the unwanted or unexpected Miralax side effects: fall, hip fracture on Feb 06, 2012 from UNITED STATES Additional patient health information: Female , weighting 138.2 lb, . Miralax dosage: 17 Mg, Qd.
Associated medications used:
  • Keppra (1250 Mg, Daily)
  • Exjade (875 Mg, Daily)
  • Tramadol Hcl (50 Mg, Tid)
  • Ondansetron Hcl
  • Exjade (1500 Mg, Daily)
  • Exjade (1000 Mg, Daily)
Patient was hospitalized.

Cardiac Failure Congestive, Overdose, Respiratory Depression, Pain (8121273-8)
Adverse event was reported on Jan 30, 2012 by a Female taking Miralax /00754501/ (Dosage: N/A) . Location: UNITED STATES , 95 years of age, Patient felt the following Miralax side effects: cardiac failure congestive, overdose, respiratory depression, pain.
Multiple prescriptions taken:
  • Namenda
  • Lanoxin
  • Fentanyl-100 (Changed Q72h)
  • Oxygen (About 2 Liters)
  • Carvedilol
  • Fentanyl-100 (Changed Q72h)
  • Cozaar
  • Metformin Hcl


Personality Change, Social Avoidant Behaviour, Abnormal Behaviour, Aggression, Anxiety, Product Substitution Issue (8115323-2)
on Feb 06, 2012 Female from UNITED STATES , child 5 years of age, weighting 32.00 lb, was diagnosed with
  • constipation
and was treated with Miralax. After Miralax was administered, patient encountered several Miralax side effects: personality change, social avoidant behaviour, abnormal behaviour, aggression, anxiety, product substitution issue. Miralax dosage: 8.5grams.

Cellulitis, Thrombosis, Thrombocytopenia (8114945-2)
on Jan 25, 2012 Male from UNITED STATES , 71 years of age, weighting 202.7 lb, was treated with Miralax. Directly after, patient experienced the unwanted or unexpected Miralax side effects: cellulitis, thrombosis, thrombocytopenia. Miralax dosage: N/A.
Associated medications used:
  • Zyrtec
  • Benadryl
  • M.v.i.
  • Potassium Chloride
  • Acetaminophen
  • Docusate
  • Prevacid
  • Compazine
Patient was hospitalized.

Showing 1-25 of 424 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Miralax Information

Alternative MIRALAX Names:POLYETHYL

Active Ingredient: POLYETHYL

More About Miralax

Side Effects reported to FDA: 424. View Miralax Adverse Reports

Miralax safety alerts: No

Reported deaths: 17

Reported hospitalizations: 97

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