Morphine Side Effects

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Morphine Safety Reports

Total Morphine reports: 473.
Morphine FDA safety alerts: 2002 2003 2005 2007 .
Reported deaths: 162    Reported hospitalizations: 144.
Take Morphine Side Effects Survey or Share Your Morphine Story.
Reported Morphine Side Effects: overdose, cardio-respiratory arrest, death, loss of consciousness, respiratory depression, nausea, somnolence, accidental overdose, confusional state, depressed level of consciousness, vomiting.
More About Morphine.

< Previous  Showing 101-150 of 473 Next >

Morphine Side Effects Report #5294592-0
Health Professional from UNITED STATES reported MORPHINE problem on Apr 06, 2007. Female patient, 27 years of age, was diagnosed with diabetic neuropathy, smoker, neuralgia, diabetes mellitus insulin-dependent, alcohol use and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: irritability, overdose, pain, renal failure. MORPHINE dosage: 30 MG, QID. During the same period patient was treated with ALBUTEROL, NEURONTIN, INSULIN, ALCOHOL. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5295154-1
MORPHINE problem was reported by a Consumer or non-health professional from on Apr 10, 2007. Female patient, 33 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cognitive disorder, constipation, post lumbar puncture syndrome, sedation. MORPHINE dosage: unknown. Patient recovered.

Morphine Side Effects Report #5297382-8
Pharmacist from UNITED STATES reported MORPHINE problem on Apr 10, 2007. Female patient was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: incorrect dose administered. MORPHINE dosage: unknown. During the same period patient was treated with DEMEROL. Patient recovered.

Morphine Side Effects Report #5297805-4
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Apr 13, 2007. Male patient, weighting 124.0 lb, was diagnosed with prostate cancer metastatic, metastases to bone and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: bone pain, cancer pain, diarrhoea, discomfort, loss of consciousness, overdose, respiratory depression. MORPHINE dosage: 45MG SR BID PO. Patient died on 02/26/2007.

Morphine Side Effects Report #5301095-3
Consumer or non-health professional from reported MORPHINE problem on Apr 13, 2007. Male patient, 60 years of age, was diagnosed with analgesic effect, inguinal hernia repair, laparoscopic surgery and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: acidosis, grand mal convulsion, hypercapnia, respiratory rate decreased, subcutaneous emphysema. MORPHINE dosage: unknown. During the same period patient was treated with CARBON DIOXIDE, CARBON DIOXIDE. Patient recovered.

Morphine Side Effects Report #5302155-3
MORPHINE problem was reported by a Pharmacist from UNITED STATES on Apr 16, 2007. Male patient was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: incorrect dose administered. MORPHINE dosage: 10MG ADMINISTERED ONCE IT. Patient recovered.

Morphine Side Effects Report #5302592-7
Consumer or non-health professional from UNITED STATES reported MORPHINE problem on Apr 16, 2007. Female patient was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: dyspnoea. MORPHINE dosage: 15 MG QD X 2 DAYS. Patient died on 01/10/2007.

Morphine Side Effects Report #5305447-7
MORPHINE problem was reported by a Consumer or non-health professional from on Apr 19, 2007. Male patient, 17 years of age, was treated with MORPHINE. MORPHINE dosage: unknown. Patient died on 04/15/2007.

Morphine Side Effects Report #5311450-3
Pharmacist from UNITED STATES reported MORPHINE problem on Apr 26, 2007. Male patient, 60 years of age, weighting 188.9 lb, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: dizziness, nausea, vomiting. MORPHINE dosage: unknown. During the same period patient was treated with AMOXICILLIN, BUPROPION, TRAZODONE, FLUOXETINE, OMEPRAZOLE, FENTANYL, ACETAMINOPHEN, CHLORHEXIDINE GLUCONATE. Patient recovered.

Morphine Side Effects Report #5312105-1
MORPHINE problem was reported by a Consumer or non-health professional from on Apr 18, 2007. Female patient, 80 years of age, was diagnosed with pain, breakthrough pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, balance disorder, chest pain, hallucination, visual, restlessness, vomiting. MORPHINE dosage: unknown. During the same period patient was treated with OXYCODONE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5312169-5
Consumer or non-health professional from reported MORPHINE problem on Apr 18, 2007. Male patient, 58 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: confusional state, constipation, faecaloma, intestinal perforation, libido decreased, overdose, somnolence, weight increased. MORPHINE dosage: unknown. Patient recovered.

Morphine Side Effects Report #5312564-4
MORPHINE problem was reported by a Consumer or non-health professional from on Apr 18, 2007. Male patient, 58 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: confusional state, constipation, faecaloma, intestinal perforation, libido decreased, overdose, somnolence, weight increased. MORPHINE dosage: unknown. Patient recovered.

Morphine Side Effects Report #5312712-6
Consumer or non-health professional from reported MORPHINE problem on Apr 18, 2007. Female patient, 60 years of age, was diagnosed with palliative care, depression and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: blood creatinine increased, body temperature increased, calcium ionised increased, confusional state, oxygen saturation decreased, respiratory rate decreased, rhonchi, somnolence. MORPHINE dosage: unknown. During the same period patient was treated with AMITRIPTYLINE, TRAZODONE, BROMAZEPAM. Patient recovered.

Morphine Side Effects Report #5316206-3
MORPHINE problem was reported by a Physician from on May 03, 2007. Male patient, 41 years of age, weighting 158.7 lb, was diagnosed with ear infection, sleep disorder, ear pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardiac valve disease, overdose, pulmonary oedema. MORPHINE dosage: unknown. During the same period patient was treated with SUBUTEX, AMOXICILLIN, DIHYDROCODEINE BITARTRATE, DOTHIEPIN HYDROCHLORIDE, IBUPROFEN, LOCORTEN. Patient died on 11/29/2005.

Morphine Side Effects Report #5316671-1
Health Professional from UNITED STATES reported MORPHINE problem on Apr 12, 2007. Male patient, 47 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: injection site mass, intraspinal abscess, streptococcal infection. MORPHINE dosage: 32 MG, DAILY. During the same period patient was treated with MORPHINE SULPHATE. Patient was hospitalized and became disabled. Patient recovered.

Morphine Side Effects Report #5316787-X
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on May 01, 2007. Female patient, 41 years of age, weighting 190.0 lb, was diagnosed with back pain, fibromyalgia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: overdose. MORPHINE dosage: unknown. Patient recovered.

Morphine Side Effects Report #5317429-X
Consumer or non-health professional from UNITED STATES reported MORPHINE problem on May 03, 2007. Male patient, 54 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: angioedema, rash. MORPHINE dosage: 60 MG BID PO. Patient recovered.

Morphine Side Effects Report #5321405-0
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on May 07, 2007. Male patient, 71 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: mental status changes. MORPHINE dosage: 90MG QD PO. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5322216-2
Consumer or non-health professional from reported MORPHINE problem on May 02, 2007. Male patient, 41 years of age, weighting 158.7 lb, was diagnosed with ear infection, sleep disorder, ear pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: aortic valve calcification, aortic valve stenosis, left ventricular hypertrophy, overdose, pulmonary oedema. MORPHINE dosage: unknown. During the same period patient was treated with SUBUTEX, AMOXICILLIN, DIHYDROCODEINE BITARTRATE, DOTHIEPIN HYDROCHLORIDE, IBUPROFEN, LOCORTEN. Patient died on 11/29/2005.

Morphine Side Effects Report #5322486-0
MORPHINE problem was reported by a Consumer or non-health professional from on May 03, 2007. Female patient, 35 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: agitation, anaphylactic shock, chills, intentional overdose, rash, somnolence. MORPHINE dosage: unknown. During the same period patient was treated with LEXOMIL. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5324821-6
Physician from AUSTRALIA reported MORPHINE problem on May 10, 2007. Female patient, 61 years of age, was diagnosed with multiple myeloma and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: bone disorder, osteonecrosis, pain in jaw, toothache. MORPHINE dosage: unknown. During the same period patient was treated with ZOMETA, STEROIDS NOS. Patient recovered.

Morphine Side Effects Report #5326023-6
MORPHINE problem was reported by a Health Professional from UNITED STATES on May 14, 2007. Male patient, 50 years of age, weighting 235.0 lb, was diagnosed with chest pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: chest pain. MORPHINE dosage: 2MG PRN IVP. Patient recovered.

Morphine Side Effects Report #5326515-X
Physician from UNITED STATES reported MORPHINE problem on Apr 30, 2007. Male patient, 55 years of age, was diagnosed with analgesic effect, muscle spasms and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: granuloma, spinal cord compression. MORPHINE dosage: unknown. During the same period patient was treated with MORPHINE SULPHATE, MORPHINE SULPHATE, MORPHINE SULPHATE. Patient recovered.

Morphine Side Effects Report #5326520-3
MORPHINE problem was reported by a Physician from UNITED STATES on Apr 30, 2007. Male patient, 45 years of age, was diagnosed with back disorder and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: catheter related complication, fibroma, granuloma, spinal cord compression, spinal cord neoplasm. MORPHINE dosage: unknown. Patient recovered.

Morphine Side Effects Report #5327749-0
Consumer or non-health professional from reported MORPHINE problem on May 08, 2007. Male patient, 82 years of age, was diagnosed with dyspnoea, chronic obstructive pulmonary disease and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: confusional state, constipation, dehydration, eating disorder, sepsis, somnolence, urinary tract infection, vomiting. MORPHINE dosage: 20 MG, Q12H. During the same period patient was treated with MORPHINE SULPHATE, MORPHINE SULPHATE, OXYGEN, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5328989-7
MORPHINE problem was reported by a Consumer or non-health professional from on May 14, 2007. Female patient, 74 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: bronchospasm, respiratory acidosis. MORPHINE dosage: 60 MG, DAILY. During the same period patient was treated with SEVREDOL, VALIUM, LIORESAL, DEROXAT, DAFALGAN, IRBESARTAN, GINKORT, RIVOTRIL. Patient recovered.

Morphine Side Effects Report #5328991-5
Consumer or non-health professional from reported MORPHINE problem on May 16, 2007. Male patient, 62 years of age, was diagnosed with pain, psoriasis and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: constipation, dehydration, diarrhoea, impaired healing, insomnia, oral intake reduced, pain in extremity. MORPHINE dosage: unknown. During the same period patient was treated with NEOTIGASON, BECLOMETHASONE DIPROPIONATE, CAPASAL, COAL TAR, MIRTAZAPINE. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5329120-4
MORPHINE problem was reported by a Physician from on May 16, 2007. Male patient, 62 years of age, was diagnosed with pain, psoriasis and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: bone pain, constipation, dehydration, diarrhoea, enthesopathy, impaired healing, insomnia, mobility decreased, neck pain. MORPHINE dosage: unknown. During the same period patient was treated with NEOTIGASON, BECLOMETHASONE DIPROPIONATE, CAPASAL, COAL TAR, MIRTAZAPINE, OLANZAPINE, PARAFFIN, SALBUTAMOL. Patient was hospitalized and became disabled. Patient recovered.

Morphine Side Effects Report #5332236-X
Consumer or non-health professional from reported MORPHINE problem on May 07, 2007. Male patient, 60 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: acidosis, grand mal convulsion, respiratory rate decreased, subcutaneous emphysema. MORPHINE dosage: 20 MG, SEE TEXT. During the same period patient was treated with ANAESTHETICS. Patient recovered.

Morphine Side Effects Report #5334026-0
MORPHINE problem was reported by a Consumer or non-health professional from on May 22, 2007. Male patient, 38 years of age, weighting 551.2 lb, was diagnosed with maintenance of anaesthesia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: hypercapnia, loss of consciousness, obstructive airways disorder. MORPHINE dosage: unknown. During the same period patient was treated with PARACETAMOL, DESFLURANE, REMIFENTANIL, ROCURONIUM BROMIDE. Patient recovered.

Morphine Side Effects Report #5336675-2
Pharmacist from UNITED STATES reported MORPHINE problem on May 24, 2007. Female patient, 72 years of age, weighting 111.3 lb, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: blood ph decreased, loss of consciousness, mental status changes, miosis, pco2 increased, po2 decreased, respiratory depression, respiratory rate decreased, sedation. MORPHINE dosage: 60MG BID PO. During the same period patient was treated with MORPHINE SULPHATE SOLUABLE. Patient recovered.

Morphine Side Effects Report #5337440-2
MORPHINE problem was reported by a Consumer or non-health professional from on May 24, 2007. Male patient, 43 years of age, was diagnosed with pancreatic carcinoma metastatic and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: colitis, gastrointestinal hypomotility. MORPHINE dosage: unknown. During the same period patient was treated with CAPECITABINE, PACLITAXEL, CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5339841-5
Physician from UNITED KINGDOM reported MORPHINE problem on May 15, 2007. Male patient, 60 years of age, was diagnosed with laparoscopic surgery and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: acidosis, grand mal convulsion, hypercapnia, post procedural complication, respiratory rate decreased, subcutaneous emphysema. MORPHINE dosage: 20 MG, INTRAVENOUS. During the same period patient was treated with CARBON DIOXIDE. Patient recovered.

Morphine Side Effects Report #5341991-4
MORPHINE problem was reported by a Pharmacist from UNITED STATES on May 30, 2007. Male patient, 63 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, heart rate increased, sedation, unresponsive to stimuli. MORPHINE dosage: unknown. During the same period patient was treated with LORAZEPAM. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5343965-6
Pharmacist from UNITED STATES reported MORPHINE problem on May 31, 2007. Male patient, 42 years of age, was diagnosed with neuralgia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: dyspnoea, hypoventilation, loss of consciousness, oxygen saturation decreased, somnolence. MORPHINE dosage: unknown. During the same period patient was treated with BACLOFEN. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5347655-5
MORPHINE problem was reported by a Health Professional from UNITED STATES on June 04, 2007. Male patient, 50 years of age, weighting 235.0 lb, was diagnosed with chest pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: chest pain, feeling abnormal. MORPHINE dosage: 2MG PRN IVP. Patient recovered.

Morphine Side Effects Report #5348119-5
Consumer or non-health professional from reported MORPHINE problem on June 04, 2007. Female patient, weighting 5.51 lb, was diagnosed with pain, epidural anaesthesia and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: neonatal disorder, respiratory arrest. MORPHINE dosage: unknown. During the same period patient was treated with LOCAL ANESTHETIC. Patient recovered.

Morphine Side Effects Report #5352412-X
MORPHINE problem was reported by a Pharmacist from UNITED STATES on June 07, 2007. Male patient, 60 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, lethargy, mental status changes, respiratory depression. MORPHINE dosage: 30MG BID PO. During the same period patient was treated with OXYCODONE. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5355652-9
Pharmacist from UNITED STATES reported MORPHINE problem on June 12, 2007. Female patient was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: bradycardia, circulatory collapse, eye rolling, overdose, respiratory arrest, skin discolouration, tongue disorder. MORPHINE dosage: unknown. Patient recovered.

Morphine Side Effects Report #5357102-5
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on June 05, 2007. Female patient, 48 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, completed suicide, respiratory arrest. MORPHINE dosage: unknown. Patient died on 01/01/2003.

Morphine Side Effects Report #5357103-7
Consumer or non-health professional from UNITED STATES reported MORPHINE problem on June 05, 2007. Female patient, 25 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, respiratory arrest. MORPHINE dosage: unknown. During the same period patient was treated with BENZODIAZEPINE, AMPHETAMINE. Patient died on 01/01/2003.

Morphine Side Effects Report #5357261-4
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on June 05, 2007. Female patient, 17 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, respiratory arrest. MORPHINE dosage: unknown. Patient died on 01/01/2003.

Morphine Side Effects Report #5357396-6
Pharmacist from UNITED STATES reported MORPHINE problem on June 12, 2007. Male patient, 76 years of age, weighting 185.0 lb, was diagnosed with chest pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: injection site irritation, injection site pain. MORPHINE dosage: 4MG X1 IV. Patient recovered.

Morphine Side Effects Report #5357405-4
MORPHINE problem was reported by a Consumer or non-health professional from UNITED STATES on June 05, 2007. Female patient, 51 years of age, was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, respiratory arrest. MORPHINE dosage: unknown. During the same period patient was treated with VENLAFAXINE, COCAINE. Patient died on 01/01/2003.

Morphine Side Effects Report #5357723-X
Consumer or non-health professional from reported MORPHINE problem on June 12, 2007. Female patient, 40 years of age, was diagnosed with back pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: abnormal behaviour, accidental overdose, acidosis, cognitive disorder, faecal incontinence, headache, hypoxia, leukoencephalopathy, loss of consciousness. MORPHINE dosage: unknown. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5363051-9
MORPHINE problem was reported by a Pharmacist from UNITED STATES on May 31, 2007. Female patient, 40 years of age, was diagnosed with pain management and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: fall, international normalised ratio increased, pain. MORPHINE dosage: unknown. During the same period patient was treated with LIQUID OXYDOSE, CIPRO, VFEND. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5366270-0
Pharmacist from UNITED STATES reported MORPHINE problem on June 19, 2007. Male patient, 88 years of age, weighting 244.7 lb, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: pruritus. MORPHINE dosage: 30MG BID PO. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5366313-4
MORPHINE problem was reported by a Pharmacist from UNITED STATES on June 20, 2007. Male patient, 74 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: myoclonus. MORPHINE dosage: 400MG BID PO. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5367101-5
Pharmacist from UNITED STATES reported MORPHINE problem on June 20, 2007. Male patient, 61 years of age, was diagnosed with pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: accidental overdose, confusional state, depressed level of consciousness, sedation. MORPHINE dosage: 60MG TID PO. During the same period patient was treated with OXYCODONE. Patient was hospitalized. Patient recovered.

Morphine Side Effects Report #5367886-8
MORPHINE problem was reported by a Consumer or non-health professional from on June 21, 2007. Female patient was diagnosed with procedural pain and was treated with MORPHINE. After drug was administered, patient experienced the following problems/side effects: apnoea, obstructive airways disorder, pulse absent. MORPHINE dosage: 2 MG BOLUS EVERY 8 MIN WITH 1-MG/H INFUSION. Patient died.

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Drug Information: Morphine Oral

URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682133.html

(mor' feen)

IMPORTANT WARNING:

Morphine is available as long acting capsules or tablets. These capsules or tablets contain enough morphine to relieve pain for 12 or 24 hours and are designed to release the medication slowly over that period of time. It is very important not to split, chew, or crush these tablets or capsules and not to dissolve the beads contained in the capsules in any liquid before you swallow them. This would release all of the medication into your body at once and could cause serious health problems or death.If you are taking Oramorph® SR or MS Contin® brand long-acting tablets or Avinza® or Kadian® brand long-acting capsules, you should swallow the tablets or capsules whole. If you are unable to swallow the capsules, you can carefully open a capsule, sprinkle all of the beads that it contains on a spoonful of cold or room temperature applesauce, and swallow the entire mixture immediately without chewing or crushing the beads. Then rinse your mouth with a little water and swallow the water to be sure that you have swallowed all the medication. Do not save mixtures of medication and applesauce for later.If you are taking Avinza® brand long-acting capsules, you should not drink any drinks that contain alcohol or take any prescription or non-prescription medications that contain alcohol. Ask your doctor or pharmacist or check the list of ingredients if you do not know if a medication contains alcohol. Alcohol may cause the morphine in Avinza® brand long-acting capsules to be released in your body too quickly, causing serious health problems or death.

Why is this medication prescribed?

Morphine is used to relieve moderate to severe pain. Morphine long-acting tablets and capsules are only used by patients who are expected to need medication to relieve moderate to severe pain around-the-clock for longer than a few days. Morphine is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the body senses pain.

How should this medicine be used?

Morphine comes as a tablet, a solution (liquid), a controlled- or extended-release (long-acting) tablet, and a controlled- or sustained-release (long-acting) capsule all to take by mouth. The regular tablet and liquid usually are taken every 4 hours. The long acting tablet is usually taken every 8-12 hours. Kadian ®brand long-acting capsules are usually taken with or without food every 12 hours or every 24 hours. Avinza® brand long acting capsules are usually taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

If you are taking morphine solution, use the spoon or dropper that comes with the medication to measure your dose. Be sure that you know how many milliliters of the solution you should take. Ask your pharmacist if you have any questions about how much medication you should take or how to use the spoon or dropper.

If you are taking Kadian® brand long-acting capsules and you have a gastrostomy tube (surgically inserted feeding tube), ask your doctor or pharmacist how to administer the medication through your tube.

Your doctor may start you on a low dose of morphine and gradually increase your dose until your pain is controlled. Your doctor may adjust your dose at any time during your treatment if your pain is not controlled. If you feel that your pain is not controlled, call your doctor. Do not change the dose of your medication without talking to your doctor.

Morphine can be habit-forming. Take morphine exactly as directed. Do not take a larger dose, take it more often, or take it for a longer period of time or in a different way than prescribed by your doctor.

Do not stop taking morphine without talking to your doctor. Your doctor may decrease your dose gradually. If you suddenly stop taking morphine, you may experience withdrawal symptoms such as anxiety; sweating; difficulty falling asleep or staying asleep; chills; shaking of a part of your body that you cannot control; upset stomach; diarrhea; runny nose, sneezing or coughing; hair on your skin standing on end; or hallucinating (seeing things or hearing voices that do not exist).

Other uses for this medicine

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before taking morphine,

  • tell your doctor and pharmacist if you are allergic to morphine, any other medications, or any of the inactive ingredients in the type of morphine tablets, capsules, or liquid you plan to take. Ask your pharmacist for a list of the inactive ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin);antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines (found in cold and allergy medications); beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); buprenorphine (Subutex, in Suboxone);butorphanol (Stadol); cimetidine (Tagamet); diuretics ('water pills'); medications for anxiety, mental illness, pain, seizures, or upset stomach; muscle relaxants; nalbuphine (Nubain); pentazocine (Talwin, in Talacen); sedatives; sleeping pills; and tranquilizers. Also tell your doctor if you are taking any of the following medications or if you have stopped taking them within the past 2 weeks: monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), procarbazine (Matulane), selegiline (Eldepryl), and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.
  • tell your doctor if you drink or have ever drunk large amounts of alcoholand if you have ever had major surgery. Also tell your doctor if you have or have ever had a head injury; a brain tumor; seizures; mental illness; difficulty swallowing; lung disease such as asthma, chronic obstructive pulmonary disease (COPD; a group of diseases that cause gradual loss of lung function), or other breathing problems; prostatic hypertrophy (enlargement of a male reproductive gland); urinary problems; low blood pressure; irregular heartbeat; Addison's disease (condition in which the body does not make enough of certain natural substances); or liver, kidney, pancreatic, intestinal, or gallbladder disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking morphine, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking morphine.
  • you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
  • talk to your doctor about the safe use of alcohol while you are taking this medication.
  • you should know that morphine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

What special dietary instructions should I follow?

Drink plenty of fluids while you are taking this medication.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Morphine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dizziness
  • lightheadedness
  • drowsiness
  • upset stomach
  • vomiting
  • constipation
  • diarrhea
  • loss of appetite
  • weight loss
  • changes in ability to taste food
  • dry mouth
  • sweating
  • weakness
  • headache
  • agitation
  • nervousness
  • mood changes
  • confusion
  • difficulty falling asleep or staying asleep
  • stiff muscles
  • shaking of a part of your body that you cannot control
  • double vision
  • red eyes
  • small pupils (black circles in the middle of the eyes
  • eye movements that you cannot control
  • chills
  • flu symptoms
  • decreased sexual desire or ability
  • difficulty urinating or pain when urinating

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

  • slow, shallow, or irregular breathing
  • blue or purple color to the skin
  • fast or slow heartbeat
  • seizures
  • hallucinations (seeing things or hearing voices that do not exist)
  • blurred vision
  • fainting
  • hives
  • rash
  • itching
  • tightness in the throat
  • difficulty swallowing
  • swelling of the arms, hands, feet, ankles, or lower legs

Morphine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Store morphine in a safe place so that no one else can take it accidentally or on purpose. Keep track of how many tablets or capsules or how much liquid is left so you will know if any medication is missing.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • slow, shallow, or irregular breathing
  • sleepiness
  • loss of consciousness
  • limp muscles
  • cold, clammy skin
  • small pupils
  • slow heartbeat
  • blurred vision
  • upset stomach
  • fainting

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. This prescription is not refillable. If you are taking morphine to control your pain on a long term basis, be sure to schedule appointments with your doctor so that you do not run out of medication. If you are taking morphine on a short term basis, call your doctor if you continue to experience pain after you finish the medication.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand name(s):

  • Avinza®
  • Kadian®
  • MS Contin®
  • Oramorph® SR
  • Roxanol® 100
  • Roxanol®
  • Roxanol®-T

Ask Our Patient Community about Morphine

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PatientsVille.com does not provide medical advice, diagnosis or treatment. The information contained on PatientsVille.com site has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of adverse drug reactions or for establishing or changing of patient treatments.


Thank you for visiting Patientsville.com. We hope you found our information about prescription drug side effects helpful. The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Thank you for visiting Patientsville.net. Hope you enjoyed finding Morphine safety information and found answers to Your Questions about Morphine side effects