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Morphine Side Effects

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Common Morphine Side Effects


The most commonly reported Morphine side effects (click to view or check a box to report):

Death (402)
Overdose (371)
Completed Suicide (330)
Somnolence (311)
Nausea (274)
Cardio-respiratory Arrest (260)
Cardiac Arrest (252)
Confusional State (251)
Vomiting (241)
Respiratory Arrest (229)
Dyspnoea (211)
Product Quality Issue (194)
Toxicity To Various Agents (188)
Loss Of Consciousness (186)
Constipation (185)
Accidental Overdose (184)
Respiratory Depression (181)
Hypotension (179)
Pain (173)
Depressed Level Of Consciousness (166)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Morphine Side Effects Reported to FDA



Morphine Side Effect Report#9995000
Abdominal Pain, Intestinal Obstruction, Hydronephrosis, Caesarean Section, Exposure During Pregnancy
This is a report of a 22-year-old female patient (weight: NA) from Country Not Specified, suffering from the following health symptoms/conditions: abdominal pain, who was treated with Morphine Sulfate (dosage: 40 Mg, start time: NS), combined with:
  • Oxynorm (50 Mg 2-4 Hourly)
and developed a serious reaction and side effect(s): Abdominal Pain, Intestinal Obstruction, Hydronephrosis, Caesarean Section, Exposure During Pregnancy after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Morphine Sulfate treatment in female patients, resulting in Abdominal Pain side effect. The patient was hospitalized.
Morphine Side Effect Report#9994656
Chest Discomfort, Dyspnoea, Colonic Abscess, Appendicitis Perforated
This report suggests a potential Morphine Sulfate Chest Discomfort side effect(s) that can have serious consequences. A 11-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: pain and used Morphine Sulfate (dosage: NA) starting
Jan 03, 2014. After starting Morphine Sulfate the patient began experiencing various side effects, including: Chest Discomfort, Dyspnoea, Colonic Abscess, Appendicitis PerforatedAdditional drugs used concurrently: NA. Although Morphine Sulfate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Chest Discomfort, may still occur.
Morphine Side Effect Report#9987907
Maternal Exposure During Pregnancy
This Maternal Exposure During Pregnancy problem was reported by a health professional from GB. A 22-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: pain. On NS this consumer started treatment with Morphine Sulfate (dosage: 20 Mg,bd). The following drugs were being taken at the same time: NA. When using Morphine Sulfate, the patient experienced the following unwanted symptoms/side effects: Maternal Exposure During PregnancyAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Maternal Exposure During Pregnancy, may become evident only after a product is in use by the general population.
Morphine Side Effect Report#9981852
Respiratory Depression, Mental Status Changes
This Respiratory Depression side effect was reported by a pharmacist from US. A 54-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Morphine (drug dosage: NA), which was initiated on
Jan 13, 2014. Concurrently used drugs: NA..After starting to take Morphine the consumer reported adverse symptoms, such as: Respiratory Depression, Mental Status ChangesThese side effects may potentially be related to Morphine. The patient was hospitalized.
Morphine Side Effect Report#9973489
Meningioma, Activities Of Daily Living Impaired, Mental Disorder
This is a report of a 55-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: pain, who was treated with Morphine Sulfate (dosage: Unk, start time: NS), combined with:
  • Percocet (Unk)
  • Vicodin (Unk)
  • Demerol (Unk)
  • Valium
  • Klonopin
  • Soma
  • Prempro
and developed a serious reaction and side effect(s): Meningioma, Activities Of Daily Living Impaired, Mental Disorder after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Morphine Sulfate treatment in female patients, resulting in Meningioma side effect.
Morphine Side Effect Report#9971835
Polyneuropathy Chronic, Paralysis, Nausea
This report suggests a potential Morphine Sulfate Polyneuropathy Chronic side effect(s) that can have serious consequences. A 79-year-old female patient (weight: NA) from SE was diagnosed with the following symptoms/conditions: neuritis and used Morphine Sulfate (dosage: Unk) starting NS. After starting Morphine Sulfate the patient began experiencing various side effects, including: Polyneuropathy Chronic, Paralysis, NauseaAdditional drugs used concurrently: NA.The patient was hospitalized. Although Morphine Sulfate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Polyneuropathy Chronic, may still occur.
Morphine Side Effect Report#9962052
Constipation, Abdominal Pain
This Constipation problem was reported by a pharmacist from US. A 69-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: pain. On
Apr 04, 2013 this consumer started treatment with Morphine (dosage: NA). The following drugs were being taken at the same time:
  • Acetaminophen/hydrocodone (5/325 Mg Prn Po)
When using Morphine, the patient experienced the following unwanted symptoms/side effects: Constipation, Abdominal PainThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Constipation, may become evident only after a product is in use by the general population.
Morphine Side Effect Report#9956371
Adenocarcinoma Gastric, Abdominal Pain, Product Deposit
This Adenocarcinoma Gastric side effect was reported by a health professional from CH. A 45-year-old male patient (weight:NA) experienced the following symptoms/conditions: abdominal pain.The patient was prescribed Morphine (drug dosage: 0.005 %, Unk), which was initiated on NS. Concurrently used drugs: NA..After starting to take Morphine the consumer reported adverse symptoms, such as: Adenocarcinoma Gastric, Abdominal Pain, Product DepositThese side effects may potentially be related to Morphine.
Morphine Side Effect Report#9952359
Urticaria
This is a report of a 77-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Morphine (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Urticaria after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Morphine treatment in male patients, resulting in Urticaria side effect.
Morphine Side Effect Report#9949802
Accidental Overdose
This report suggests a potential Morphine Sulfate Accidental Overdose side effect(s) that can have serious consequences. A 17-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Morphine Sulfate (dosage: Unk) starting NS. After starting Morphine Sulfate the patient began experiencing various side effects, including: Accidental OverdoseAdditional drugs used concurrently:
  • Oxycodone Hydrochloride (Unk)
  • Cocaine (Unk)
Although Morphine Sulfate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Accidental Overdose, may still occur.
Morphine Side Effect Report#9943288
Urticaria
This Urticaria problem was reported by a consumer or non-health professional from US. A 59-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Morphine (dosage: NA). The following drugs were being taken at the same time: NA. When using Morphine, the patient experienced the following unwanted symptoms/side effects: UrticariaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Urticaria, may become evident only after a product is in use by the general population.
Morphine Side Effect Report#9934687
Pneumonia Aspiration, Accidental Overdose, Substance Abuse
This Pneumonia Aspiration side effect was reported by a consumer or non-health professional from CA. A 47-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Morphine Sulfate (drug dosage: Unk), which was initiated on NS. Concurrently used drugs:
  • Codeine (Unk)
  • Opioids
  • Diazepam (Unk)
  • Paroxetine (Unk)
  • Zoplicone
.After starting to take Morphine Sulfate the consumer reported adverse symptoms, such as: Pneumonia Aspiration, Accidental Overdose, Substance AbuseThese side effects may potentially be related to Morphine Sulfate.
Morphine Side Effect Report#9934224
Vomiting
This is a report of a 65-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Morphine (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Vomiting after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Morphine treatment in female patients, resulting in Vomiting side effect.
Morphine Side Effect Report#9933107
Rash, Nausea
This report suggests a potential Morphine Rash side effect(s) that can have serious consequences. A 55-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Morphine (dosage: NA) starting NS. After starting Morphine the patient began experiencing various side effects, including: Rash, NauseaAdditional drugs used concurrently: NA. Although Morphine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Rash, may still occur.
Morphine Side Effect Report#9925415
Chest Discomfort, Sensation Of Heaviness
This Chest Discomfort problem was reported by a pharmacist from US. A 15-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: pain. On NS this consumer started treatment with Morphine (dosage: 90 Days From Cpd Date). The following drugs were being taken at the same time:
  • Acetaminophen
When using Morphine, the patient experienced the following unwanted symptoms/side effects: Chest Discomfort, Sensation Of HeavinessAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Chest Discomfort, may become evident only after a product is in use by the general population.
Morphine Side Effect Report#9925414
Mucosal Inflammation, Chest Discomfort, Chest Discomfort
This Mucosal Inflammation side effect was reported by a pharmacist from US. A 13-year-old female patient (weight:NA) experienced the following symptoms/conditions: pain.The patient was prescribed Morphine (drug dosage: 90 Days From Cpd Date), which was initiated on NS. Concurrently used drugs:
  • Ondansetron
.After starting to take Morphine the consumer reported adverse symptoms, such as: Mucosal Inflammation, Chest Discomfort, Chest DiscomfortThese side effects may potentially be related to Morphine.
Morphine Side Effect Report#9925370
Confusional State, Abnormal Behaviour, Anxiety
This is a report of a 56-year-old male patient (weight: NA) from ES, suffering from the following health symptoms/conditions: pain, who was treated with Morphine Sulfate (dosage: 60 Mg, 2x/day, start time:
Aug 29, 2011), combined with: NA. and developed a serious reaction and side effect(s): Confusional State, Abnormal Behaviour, Anxiety after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Morphine Sulfate treatment in male patients, resulting in Confusional State side effect. The patient was hospitalized.
Morphine Side Effect Report#9925198
Chest Pain, Crying
This report suggests a potential Morphine Chest Pain side effect(s) that can have serious consequences. A 6-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: pain and used Morphine (dosage: 90 Days From Cpd Date ?1.75 Mg ?prn/as Needed ?intravenous) starting NS. After starting Morphine the patient began experiencing various side effects, including: Chest Pain, CryingAdditional drugs used concurrently:
  • Lidocaine
  • Ns
  • Ondansetron
  • Acetaminophen
  • Dsw
  • Kcl
Although Morphine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Chest Pain, may still occur.
Morphine Side Effect Report#9922513
Tooth Loss, Tooth Disorder, Somnolence, Inadequate Analgesia
This Tooth Loss problem was reported by a consumer or non-health professional from DE. A 43-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: neck pain. On 1994 this consumer started treatment with Morphine Sulfate (dosage: Unk). The following drugs were being taken at the same time: NA. When using Morphine Sulfate, the patient experienced the following unwanted symptoms/side effects: Tooth Loss, Tooth Disorder, Somnolence, Inadequate AnalgesiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Tooth Loss, may become evident only after a product is in use by the general population.
Morphine Side Effect Report#9922510
Enterobiasis, Secretion Discharge, Local Swelling, Inadequate Analgesia
This Enterobiasis side effect was reported by a consumer or non-health professional from DE. A 43-year-old female patient (weight:NA) experienced the following symptoms/conditions: neck pain.The patient was prescribed Morphine Sulfate (drug dosage: Unk), which was initiated on NS. Concurrently used drugs: NA..After starting to take Morphine Sulfate the consumer reported adverse symptoms, such as: Enterobiasis, Secretion Discharge, Local Swelling, Inadequate AnalgesiaThese side effects may potentially be related to Morphine Sulfate. The patient was hospitalized.
Morphine Side Effect Report#9922177
Pneumonia Aspiration, Accidental Overdose, Substance Abuse
This is a report of a 47-year-old female patient (weight: NA) from CA, suffering from the following health symptoms/conditions: NA, who was treated with Morphine Sulfate (dosage: Unk, start time: NS), combined with:
  • Diazepam (Unk)
  • Codeine (Unk)
  • Paroxetine (Unk)
  • Zoplicone (Unk)
and developed a serious reaction and side effect(s): Pneumonia Aspiration, Accidental Overdose, Substance Abuse after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Morphine Sulfate treatment in female patients, resulting in Pneumonia Aspiration side effect.
Morphine Side Effect Report#9917395
Neck Pain, Musculoskeletal Pain
This report suggests a potential Morphine Sulfate Neck Pain side effect(s) that can have serious consequences. A 28-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Morphine Sulfate (dosage: Unk) starting NS. After starting Morphine Sulfate the patient began experiencing various side effects, including: Neck Pain, Musculoskeletal PainAdditional drugs used concurrently: NA. Although Morphine Sulfate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neck Pain, may still occur.
Morphine Side Effect Report#9916758
Accidental Overdose, Needle Track Marks, Fall, Tremor
This Accidental Overdose problem was reported by a consumer or non-health professional from CA. A 47-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Morphine Sulfate (dosage: 600 Mg, Single). The following drugs were being taken at the same time: NA. When using Morphine Sulfate, the patient experienced the following unwanted symptoms/side effects: Accidental Overdose, Needle Track Marks, Fall, TremorAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Accidental Overdose, may become evident only after a product is in use by the general population.
Morphine Side Effect Report#9913577
Tremor, Respiratory Rate Increased, Respiratory Acidosis, Somnolence, Slow Speech
This Tremor side effect was reported by a pharmacist from US. A 67-year-old male patient (weight:NA) experienced the following symptoms/conditions: pain.The patient was prescribed Morphine (drug dosage: NA), which was initiated on
Jan 02, 2014. Concurrently used drugs: NA..After starting to take Morphine the consumer reported adverse symptoms, such as: Tremor, Respiratory Rate Increased, Respiratory Acidosis, Somnolence, Slow SpeechThese side effects may potentially be related to Morphine. The patient was hospitalized.
Morphine Side Effect Report#9913068
Chest Discomfort
This is a report of a 14-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: pain, who was treated with Morphine (dosage: 90 Days From Cpd Date, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Chest Discomfort after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Morphine treatment in female patients, resulting in Chest Discomfort side effect.


1 of 215 


The appearance of Morphine on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Morphine Side Effects for Women?

Women Side EffectsReports
Death 170
Nausea 163
Overdose 156
Somnolence 147
Vomiting 144
Completed Suicide 136
Dyspnoea 105
Loss Of Consciousness 104
Product Quality Issue 101
Cardio-respiratory Arrest 98

What are common Morphine Side Effects for Men?

Men Side EffectsReports
Death 207
Overdose 194
Somnolence 162
Confusional State 153
Completed Suicide 138
Cardio-respiratory Arrest 122
Cardiac Arrest 118
Constipation 112
Nausea 108
Toxicity To Various Agents 105

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Morphine reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Morphine Side Effects

    Did You Have a Morphine Side Effect?

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    How Effective is Morphine for You?

    Exceeded Expectations
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    Morphine Safety Alerts, Active Ingredients, Usage Information

    NDC0054-0235
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameMorphine Sulfate
    NameMorphine Sulfate
    Dosage FormTABLET
    RouteORAL
    On market since20080317
    LabelerRoxane Laboratories, Inc
    Active Ingredient(s)MORPHINE SULFATE
    Strength(s)15
    Unit(s)mg/1
    Pharma ClassFull Opioid Agonists [MoA],Opioid Agonist [EPC]

    More About Morphine

    Side Effects reported to FDA: 5356

    Morphine safety alerts: 2012 2011 2008 2005 2003

    Reported deaths: 1114

    Reported hospitalizations: 1173

    Morphine Sulfate Injection USP, 4 mg/mL (C-II), 1 mL fill in 2.5 mL Carpuject by Hospira, Inc: Recall - May Contain More Than Intended Fill Volume

     

    [Posted 04/18/2012]

    AUDIENCE: Risk Manager, Pain Management

    ISSUE: Customer report of two Carpujects syringes containing more than the 1 mL labeled fill volume. Opioid pain medications such as morphine have life-threatening consequences if overdosed. Those consequences can include respiratory depression (slowed breathing or suspension of breathing), and low blood pressure.

    BACKGROUND: The affected product is a prefilled glass cartridge for use with the Carpuject Syringe system. The affected lot number is 10830LL, with an expiration date of April 1, 2013. Morphine Sulfate Carpujects 4 mg/mL are packaged in Slim-Pak tamper detection packages with each box containing 10 Carpujects (NDC 0409-1258-30). 

    The affected lot was distributed in January 2012. It was initially distributed to wholesalers and a limited number of hospitals in Arizona, Colorado, Hawaii, Illinois, Indiana, Michigan, Minnesota, Ohio, Texas and Virginia. 

    RECOMMENDATION: Anyone with an existing inventory of affected product should stop use and distribution and quarantine the product immediately and call Stericycle at 1-888-912-7088 to arrange for the return of the product.

    Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:

    • Complete and submit the report Online: www.fda.gov/MedWatch/report.htm
    • Download form or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178


    [04/17/2012 - Press Release - Hospira, Inc]
     

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