Moxifloxacin Side Effects
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Moxifloxacin Safety Reports reported to FDA
Total Moxifloxacin reports: 104.Moxifloxacin FDA safety alerts: No.
Reported deaths: 10 Reported hospitalizations: 58.
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Reported Moxifloxacin Side Effects: pyrexia, pain, dyspnoea, inflammation, cholecystitis, international normalised ratio increased, clostridium difficile colitis, atrial fibrillation, aspartate aminotransferase increased, alanine aminotransferase increased, blood alkaline phosphatase increased.
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Moxifloxacin Side Effects Report #5420867-8Pharmacist from UNITED STATES reported MOXIFLOXACIN problem on Aug 17, 2007. Male patient, 75 years of age, was diagnosed with upper respiratory tract infection and was treated with MOXIFLOXACIN. After drug was administered, patient experienced the following problems/side effects: clostridium difficile colitis. MOXIFLOXACIN dosage: 400MG EVERY DAY PO. Patient was hospitalized. Patient recovered.
Moxifloxacin Side Effects Report #5431797-X
MOXIFLOXACIN problem was reported by a Consumer or non-health professional from SPAIN on Aug 29, 2007. Male patient, 72 years of age, was treated with MOXIFLOXACIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea. MOXIFLOXACIN dosage: unknown. Patient recovered.
Moxifloxacin Side Effects Report #5441919-2
Pharmacist from UNITED STATES reported MOXIFLOXACIN problem on Aug 30, 2007. Male patient, 50 years of age, was diagnosed with upper respiratory tract infection and was treated with MOXIFLOXACIN. After drug was administered, patient experienced the following problems/side effects: asthenia, erythema multiforme, pain, purpura, skin exfoliation, stomatitis, toxic epidermal necrolysis. MOXIFLOXACIN dosage: 400MG EVERY DAY PO. Patient was hospitalized. Patient recovered.
Moxifloxacin Side Effects Report #5444881-1
MOXIFLOXACIN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 04, 2007. Female patient, 47 years of age, weighting 140.0 lb, was diagnosed with otitis media and was treated with MOXIFLOXACIN. After drug was administered, patient experienced the following problems/side effects: dizziness, palpitations, tremor. MOXIFLOXACIN dosage: 400MG 2X A DAY PO. Patient recovered.
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Drug Information: Moxifloxacin
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a600002.html
Why is this medication prescribed?
Moxifloxacin is in a class of drugs called fluoroquinolone antibiotics. It works by stopping the life cycle of bacteria. It is used to eliminate certain bacteria that cause infections in your lungs and sinuses. Antibiotics will not work for colds, flu, or other viral infections.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?
Moxifloxacin comes as tablet to take by mouth. It is usually taken once a day for 5 to 10 days. Moxifloxacin tablets should be swallowed whole with a full glass of water. It can be taken with or without food.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use moxifloxacin exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
Continue to take moxifloxacin even if you feel well. Do not stop taking moxifloxacin without talking to your doctor.
Other uses for this medicine
Moxifloxacin is used occasionally to treat prostatitis, osteomyelitis, traveler's diarrhea, gonorrheal cervicitis or urethritis, pelvic inflammatory disease, sinusitis, otitis media, septic arthritis, bacterial meningitis, bacteremia, and endocarditis, and to prevent infection in urological surgery. Talk to your doctor about the possible risks of using this drug for your condition.
What special precautions should I follow?
Before using moxifloxacin,
- tell your doctor and pharmacist if you are allergic to moxifloxacin, alatrofloxacin injection (Trovan), cinoxacin (Cinobac), ciprofloxacin (Cipro), enoxacin (Penetrex), gatifloxacin (Tequin), levofloxacin (Levaquin), lomefloxacin (Maxaquin), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), sparfloxacin (Zagam), trofloxacin tablets (Trovan), or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics; amiodarone (Cordarone); cisapride (Propulsid); disopyramide (Norpace); diuretics ('water pills') such as furosemide (Lasix) and hydrochlorothiazide (Hydrodiuril); erythromycin (E-Mycin, Ery-Tab, PCE, others); medications for depression or other mental diseases; nonsteroidal anti-inflammatory agents; procainamide (Pronestyl); quinidine; sotalol (Betapace); and vitamins and herbal products.
- do not take with antacids containing magnesium or aluminum (Milk of Magnesia, Riopan, Maalox, Mylanta), sucralfate (Carafate), iron or zinc supplements, vitamins that contain iron or zinc, or didanosine (Videx) tablets or pediatric powder for oral solution. Take these medications at least 8 hours before or 4 hours after moxifloxacin.
- tell your doctor if you currently have diarrhea; have or have ever had liver disease, severe cerebral arteriosclerosis, or epilepsy; or if you have, have had, or have a family history of heart disease such as irregular rhythms, low potassium levels, bradycardia, or heart attacks.
- tell your doctor if you are pregnant or plan to become pregnant, or if you are breast-feeding. If you become pregnant while using moxifloxacin, call your doctor immediately.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking moxifloxacin.
- plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Moxifloxacin may make your skin sensitive to sunlight.
- you should know that moxifloxacin may cause dizziness and lightheadedness. Do not drive a car or work on dangerous machinery until you know how moxifloxacin will affect you.
What special dietary instructions should I follow?
While taking moxifloxacin, you should drink at least eight full glasses of water or other liquid every day.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Side effects from moxifloxacin can occur. Tell your doctor if any of these symptoms are severe or do not go away:
- upset stomach
- diarrhea
- dizziness
- headache
- stomach pain
- vomiting
- change in taste
If you experience any of the following symptoms, call your doctor immediately:
- skin rash
- itching
- hives
- difficulty breathing or swallowing
- swelling of the face or throat
- fever
- yellowing of the skin or eyes
- dark urine
- pale or dark stools
- blood in urine
- sunburn or blistering
- confusion
- hallucinations
- depression
- suicidal thoughts
- fast or irregular heartbeat
- fainting
- pain, inflammation, or rupture of a tendon
- tremor
- extreme tiredness
- seizures or convulsions
- visual changes
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Moxifloxacin has not been tested in children younger than 18 years of age, so keep the medication out of reach of children.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to moxifloxacin.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the moxifloxacin, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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