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Naftidrofuryl Side Effects

Common Naftidrofuryl Side Effects


The most commonly reported Naftidrofuryl side effects (click to view or check a box to report):

Rhabdomyolysis (5)
Chromaturia (3)
Vomiting (3)
Malaise (3)
Musculoskeletal Pain (2)
Urinary Tract Infection (2)
Blood Urea Increased (2)
Blood Creatine Phosphokinase Increased (2)
Angina Pectoris (2)
Arthralgia (2)
Oesophageal Ulcer (1)
Lung Infection (1)
Abdominal Pain Upper (1)
Chest Pain (1)
Haemorrhagic Stroke (1)


If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Naftidrofuryl Side Effects Reported to FDA

The following Naftidrofuryl reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Naftidrofuryl on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Abdominal Pain Upper, Oesophageal Ulcer, Chest Pain
This is a report of a 83-year-old female patient (weight: NA) from ITALY, suffering from the following symptoms/conditions: NA, who was treated with Naftidrofuryl (naftidrofuryl) (dosage: (200), Oral Since Long Time -, start time: NS), combined with:
  • Pravastatin ((20 ), Oral Since Long Time -)
  • Aspirin
  • Furosemide ((20 ), Oral Since Long Time -)
  • Novomix (biphasic Insulin Aspart) (biphasic Insulin Aspart)
  • Nebivolol Hcl (Oral Since Long Time -)
  • Trimetazidine (trimetazidine) ((20 ), Oral Since Long Time -)
and developed a serious reaction and side effect(s). The consumer presented with:
  • Abdominal Pain Upper
  • Oesophageal Ulcer
  • Chest Pain
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Naftidrofuryl (naftidrofuryl) treatment in female patients, resulting in abdominal pain upper side effect. The patient was hospitalized.

Arthralgia, Vomiting, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Urea Increased, Malaise, Chromaturia, Musculoskeletal Pain
This report suggests a potential Naftidrofuryl Oxalate Arthralgia, Vomiting, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Urea Increased, Malaise, Chromaturia, Musculoskeletal Pain side effect(s) that can have serious consequences. A 57-year-old male patient (weight: NA) from was diagnosed with the following symptoms/conditions: NA and used Naftidrofuryl Oxalate (dosage: NA) starting May 06, 2011. Soon after starting Naftidrofuryl Oxalate the patient began experiencing various side effects, including:
  • Arthralgia
  • Vomiting
  • Rhabdomyolysis
  • Blood Creatine Phosphokinase Increased
  • Blood Urea Increased
  • Malaise
  • Chromaturia
  • Musculoskeletal Pain
Drugs used concurrently:
  • Trimethoprim (200 Mg (200 Mg,1 In 1 D), Oral)
  • Amlodipine
  • Aspirin
  • Simvastatin (40 Mg (40 Mg,1 In 1 D),oral)
  • Ranolazine (750 Mg (375 Mg,2 In 1 D), Oral : 1000 Mg (500 Mg,2 In 1 D),oral)
  • Ranolazine (750 Mg (375 Mg,2 In 1 D), Oral : 1000 Mg (500 Mg,2 In 1 D),oral)
  • Nitroglycerin
  • Carvedilol
The patient was hospitalized. Although Naftidrofuryl Oxalate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as arthralgia, may still occur.

Rhabdomyolysis, Malaise
This Rhabdomyolysis, Malaise problem was reported by a consumer or non-health professional from UNITED KINGDOM. A 57-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On Apr 07, 2011 this consumer started treatment with Naftidrofuryl Oxalate (dosage: NA). The following drugs were being taken at the same time:
  • Amlodipine
  • Nicorandil
  • Trimethoprim (200 Mg (200 Mg,unk),oral)
  • Nitroglycerin
  • Isosorbide Mononitrate
  • Simvastatin (40 Mg (40 Mg, Unk),oral)
  • Carvedilol
  • Ramipril
When commencing Naftidrofuryl Oxalate, the patient experienced the following unwanted symptoms/side effects:
  • Rhabdomyolysis
  • Malaise
The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as rhabdomyolysis, may become evident only after a product is in use by the general population.

Rhabdomyolysis, Blood Urea Increased, Angina Pectoris, Vomiting, Chromaturia, Urinary Tract Infection
This is a report of a 57-year-old male patient (weight: NA) from . The patient developed the following symptoms/conditions: NA and was treated with Naftidrofuryl Oxalate (naftidrofuryl Oxalate) (dosage: NA) starting Apr 07, 2011. Concurrently used drugs:
  • Enoxaparin Sodium
  • Aspirin
  • Nitroglycerin
  • Ramipril
  • Simvastatin (40 Mg (40 Mg, 1 In 1 D),oral)
  • Carvedilol
  • Acetaminophen
  • Trimethoprim (200 Mg (200 Mg, 1 In 1 D),oral)
Soon after that, the consumer experienced the following side effects:
  • Rhabdomyolysis
  • Blood Urea Increased
  • Angina Pectoris
  • Vomiting
  • Chromaturia
  • Urinary Tract Infection
The patient was hospitalized. This opens a possibility that Naftidrofuryl Oxalate (naftidrofuryl Oxalate) treatment could cause the above reactions, including rhabdomyolysis, and some male subjects may be more susceptible.


Musculoskeletal Pain, Rhabdomyolysis, Urinary Tract Infection, Chromaturia, Malaise, Angina Pectoris, Vomiting, Arthralgia
A 57-year-old male patient (weight: NA) from with the following symptoms/conditions: NA started Naftidrofuryl Oxalate (naftidrofuryl Oxalate) treatment (dosage: NA) on May 06, 2011. Soon after starting Naftidrofuryl Oxalate (naftidrofuryl Oxalate) treatment, the subject experienced various side effects, including:
  • Musculoskeletal Pain
  • Rhabdomyolysis
  • Urinary Tract Infection
  • Chromaturia
  • Malaise
  • Angina Pectoris
  • Vomiting
  • Arthralgia
Concurrently used drugs:
  • Glyceryl Trintrate (glyceryl Trintrate)
  • Isosorbide Mononitrate
  • Ramipril
  • Aspirin
  • Amlodipine
  • Carvedilol
  • Simvastatin (Oral)
  • Acetaminophen
The patient was hospitalized. This finding indicates that some male patients could be more vulnerable to Naftidrofuryl Oxalate (naftidrofuryl Oxalate).

Haemorrhagic Stroke, Lung Infection
A 84-year-old male patient from FRANCE (weight: NA) experienced symptoms, such as: arterial disorder,hypertension,pain,depression,thrombosis prophylaxis,hypercholesterolaemia and was treated with Naftidrofuryl(dosage: Unk). The treatment was initiated on NS. After that a consumer reported the following side effect(s):
  • Haemorrhagic Stroke
  • Lung Infection
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Naftidrofuryl efficacy:
  • Micardis Hct (1 Df, 1x/day)
  • Acetaminophen (Unk)
  • Effexor Xr (75 Mg, 1x/day)
  • Plavix (Unk)
  • Crestor (10 Mg, 1x/day)
The patient was hospitalized.

Blood Creatine Phosphokinase Increased, Rhabdomyolysis
In this report, Naftidrofuryl was administered for the following condition: NA.A 57-year-old male consumer from UNITED KINGDOM (weight: NA) started Naftidrofuryl treatment (dosage: 300 Mg, Unk) on May 20, 2011.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Blood Creatine Phosphokinase Increased
  • Rhabdomyolysis
A possible interaction with other drugs could have contributed to this reaction:
  • Ramipril (5 Mg, Unk)
  • Isosorbide Mononitrate (120 Mg, Unk)
  • Ranexa (Unk)
  • Aspirin (75 Mg, Unk)
  • Nitroglycerin
  • Nicorandil (60 Mg, Unk)
  • Simvastatin (40 Mg, Unk)
  • Amlodipine (10 Mg, Unk)
The patient was hospitalized.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Naftidrofuryl treatment could be related to the listed above side effect(s).



Top 10 Naftidrofuryl Side Effects for Women

Women Side EffectsReports
Abdominal Pain Upper 1
Chest Pain 1
Oesophageal Ulcer 1

Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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    Naftidrofuryl Safety Alerts, Active Ingredients, Usage Information

    More About Naftidrofuryl

    Side Effects reported to FDA: 7

    Naftidrofuryl safety alerts: No

    Reported hospitalizations: 2

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