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Naftidrofuryl Side Effects

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Common Naftidrofuryl Side Effects


The most commonly reported Naftidrofuryl side effects (click to view or check a box to report):

Rhabdomyolysis (5)
Chromaturia (3)
Vomiting (3)
Malaise (3)
Musculoskeletal Pain (2)
Urinary Tract Infection (2)
Blood Urea Increased (2)
Blood Creatine Phosphokinase Increased (2)
Angina Pectoris (2)
Arthralgia (2)
Oesophageal Ulcer (1)
Lung Infection (1)
Abdominal Pain Upper (1)
Chest Pain (1)
Haemorrhagic Stroke (1)


If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Naftidrofuryl Side Effects Reported to FDA



Naftidrofuryl Side Effect Report#7951368-0
Abdominal Pain Upper, Oesophageal Ulcer, Chest Pain
This is a report of a 83-year-old female patient (weight: NA) from Italy, suffering from the following health symptoms/conditions: NA, who was treated with Naftidrofuryl (naftidrofuryl) (dosage: (200), Oral Since Long Time -, start time: NS), combined with:
  • Pravastatin ((20 ), Oral Since Long Time -)
  • Aspirin
  • Furosemide ((20 ), Oral Since Long Time -)
  • Novomix (biphasic Insulin Aspart) (biphasic Insulin Aspart)
  • Nebivolol Hcl (Oral Since Long Time -)
  • Trimetazidine (trimetazidine) ((20 ), Oral Since Long Time -)
and developed a serious reaction and side effect(s): Abdominal Pain Upper, Oesophageal Ulcer, Chest Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Naftidrofuryl (naftidrofuryl) treatment in female patients, resulting in Abdominal Pain Upper side effect. The patient was hospitalized.
Naftidrofuryl Side Effect Report#7709949-5
Arthralgia, Vomiting, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Urea Increased, Malaise, Chromaturia, Musculoskeletal Pain
This report suggests a potential Naftidrofuryl Oxalate Arthralgia side effect(s) that can have serious consequences. A 57-year-old male patient (weight: NA) from was diagnosed with the following symptoms/conditions: NA and used Naftidrofuryl Oxalate (dosage: NA) starting
May 06, 2011. After starting Naftidrofuryl Oxalate the patient began experiencing various side effects, including: Arthralgia, Vomiting, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Urea Increased, Malaise, Chromaturia, Musculoskeletal PainAdditional drugs used concurrently:
  • Trimethoprim (200 Mg (200 Mg,1 In 1 D), Oral)
  • Amlodipine
  • Aspirin
  • Simvastatin (40 Mg (40 Mg,1 In 1 D),oral)
  • Ranolazine (750 Mg (375 Mg,2 In 1 D), Oral : 1000 Mg (500 Mg,2 In 1 D),oral)
  • Ranolazine (750 Mg (375 Mg,2 In 1 D), Oral : 1000 Mg (500 Mg,2 In 1 D),oral)
  • Nitroglycerin
  • Carvedilol
The patient was hospitalized. Although Naftidrofuryl Oxalate demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Arthralgia, may still occur.
Naftidrofuryl Side Effect Report#7708863-9
Rhabdomyolysis, Malaise
This Rhabdomyolysis problem was reported by a consumer or non-health professional from United Kingdom. A 57-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Apr 07, 2011 this consumer started treatment with Naftidrofuryl Oxalate (dosage: NA). The following drugs were being taken at the same time:
  • Amlodipine
  • Nicorandil
  • Trimethoprim (200 Mg (200 Mg,unk),oral)
  • Nitroglycerin
  • Isosorbide Mononitrate
  • Simvastatin (40 Mg (40 Mg, Unk),oral)
  • Carvedilol
  • Ramipril
When using Naftidrofuryl Oxalate, the patient experienced the following unwanted symptoms/side effects: Rhabdomyolysis, MalaiseThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Rhabdomyolysis, may become evident only after a product is in use by the general population.
Naftidrofuryl Side Effect Report#7704207-7
Rhabdomyolysis, Blood Urea Increased, Angina Pectoris, Vomiting, Chromaturia, Urinary Tract Infection
This Rhabdomyolysis side effect was reported by a health professional from . A 57-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Naftidrofuryl Oxalate (naftidrofuryl Oxalate) (drug dosage: NA), which was initiated on
Apr 07, 2011. Concurrently used drugs:
  • Enoxaparin Sodium
  • Aspirin
  • Nitroglycerin
  • Ramipril
  • Simvastatin (40 Mg (40 Mg, 1 In 1 D),oral)
  • Carvedilol
  • Acetaminophen
  • Trimethoprim (200 Mg (200 Mg, 1 In 1 D),oral)
.After starting to take Naftidrofuryl Oxalate (naftidrofuryl Oxalate) the consumer reported adverse symptoms, such as: Rhabdomyolysis, Blood Urea Increased, Angina Pectoris, Vomiting, Chromaturia, Urinary Tract InfectionThese side effects may potentially be related to Naftidrofuryl Oxalate (naftidrofuryl Oxalate). The patient was hospitalized.
Naftidrofuryl Side Effect Report#7693586-5
Musculoskeletal Pain, Rhabdomyolysis, Urinary Tract Infection, Chromaturia, Malaise, Angina Pectoris, Vomiting, Arthralgia
This is a report of a 57-year-old male patient (weight: NA) from , suffering from the following health symptoms/conditions: NA, who was treated with Naftidrofuryl Oxalate (naftidrofuryl Oxalate) (dosage: NA, start time:
May 06, 2011), combined with:
  • Glyceryl Trintrate (glyceryl Trintrate)
  • Isosorbide Mononitrate
  • Ramipril
  • Aspirin
  • Amlodipine
  • Carvedilol
  • Simvastatin (Oral)
  • Acetaminophen
and developed a serious reaction and side effect(s): Musculoskeletal Pain, Rhabdomyolysis, Urinary Tract Infection, Chromaturia, Malaise, Angina Pectoris, Vomiting, Arthralgia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Naftidrofuryl Oxalate (naftidrofuryl Oxalate) treatment in male patients, resulting in Musculoskeletal Pain side effect. The patient was hospitalized.
Naftidrofuryl Side Effect Report#7641454-7
Haemorrhagic Stroke, Lung Infection
This report suggests a potential Naftidrofuryl Haemorrhagic Stroke side effect(s) that can have serious consequences. A 84-year-old male patient (weight: NA) from France was diagnosed with the following symptoms/conditions: arterial disorder,hypertension,pain,depression,thrombosis prophylaxis,hypercholesterolaemia and used Naftidrofuryl (dosage: Unk) starting NS. After starting Naftidrofuryl the patient began experiencing various side effects, including: Haemorrhagic Stroke, Lung InfectionAdditional drugs used concurrently:
  • Micardis Hct (1 Df, 1x/day)
  • Acetaminophen (Unk)
  • Effexor Xr (75 Mg, 1x/day)
  • Plavix (Unk)
  • Crestor (10 Mg, 1x/day)
The patient was hospitalized. Although Naftidrofuryl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Haemorrhagic Stroke, may still occur.
Naftidrofuryl Side Effect Report#7587171-3
Blood Creatine Phosphokinase Increased, Rhabdomyolysis
This Blood Creatine Phosphokinase Increased problem was reported by a health professional from United Kingdom. A 57-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
May 20, 2011 this consumer started treatment with Naftidrofuryl (dosage: 300 Mg, Unk). The following drugs were being taken at the same time:
  • Ramipril (5 Mg, Unk)
  • Isosorbide Mononitrate (120 Mg, Unk)
  • Ranexa (Unk)
  • Aspirin (75 Mg, Unk)
  • Nitroglycerin
  • Nicorandil (60 Mg, Unk)
  • Simvastatin (40 Mg, Unk)
  • Amlodipine (10 Mg, Unk)
When using Naftidrofuryl, the patient experienced the following unwanted symptoms/side effects: Blood Creatine Phosphokinase Increased, RhabdomyolysisThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Blood Creatine Phosphokinase Increased, may become evident only after a product is in use by the general population.


The appearance of Naftidrofuryl on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Naftidrofuryl Side Effects for Women?

Women Side EffectsReports
Abdominal Pain Upper 1
Chest Pain 1
Oesophageal Ulcer 1

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Naftidrofuryl reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Naftidrofuryl Safety Alerts, Active Ingredients, Usage Information

    More About Naftidrofuryl

    Side Effects reported to FDA: 7

    Naftidrofuryl safety alerts: No

    Reported hospitalizations: 2

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