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Naftidrofuryl Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Abdominal Pain Upper, Oesophageal Ulcer, Chest Pain (7951368-0)
on Nov 16, 2011 Female from ITALY , 83 years of age, was treated with Naftidrofuryl (naftidrofuryl). Directly after, patient experienced the unwanted or unexpected Naftidrofuryl side effects: abdominal pain upper, oesophageal ulcer, chest pain. Naftidrofuryl (naftidrofuryl) dosage: (200), Oral Since Long Time -.
Associated medications used:
  • Pravastatin ((20 ), Oral Since Long Time -)
  • Aspirin
  • Furosemide ((20 ), Oral Since Long Time -)
  • Novomix (biphasic Insulin Aspart) (biphasic Insulin Aspart)
  • Nebivolol Hcl (Oral Since Long Time -)
  • Trimetazidine (trimetazidine) ((20 ), Oral Since Long Time -)
Patient was hospitalized.

Arthralgia, Vomiting, Rhabdomyolysis, Blood Creatine Phosphokinase Increased, Blood Urea Increased, Malaise, Chromaturia, Musculoskeletal Pain (7709949-5)
Patient was taking Naftidrofuryl Oxalate. Patient felt the following Naftidrofuryl side effects: arthralgia, vomiting, rhabdomyolysis, blood creatine phosphokinase increased, blood urea increased, malaise, chromaturia, musculoskeletal pain on Aug 04, 2011 from Additional patient health information: Male , 57 years of age, . Naftidrofuryl Oxalate dosage: N/A.
Multiple prescriptions taken:
  • Trimethoprim (200 Mg (200 Mg,1 In 1 D), Oral)
  • Amlodipine
  • Aspirin
  • Simvastatin (40 Mg (40 Mg,1 In 1 D),oral)
  • Ranolazine (750 Mg (375 Mg,2 In 1 D), Oral : 1000 Mg (500 Mg,2 In 1 D),oral)
  • Ranolazine (750 Mg (375 Mg,2 In 1 D), Oral : 1000 Mg (500 Mg,2 In 1 D),oral)
  • Nitroglycerin
  • Carvedilol
Patient was hospitalized.

Rhabdomyolysis, Malaise (7708863-9)
Adverse event was reported on Aug 05, 2011 by a Male taking Naftidrofuryl Oxalate (Dosage: N/A) . Location: UNITED KINGDOM , 57 years of age, After Naftidrofuryl was administered, patient encountered several Naftidrofuryl side effects: rhabdomyolysis, malaise.
Multiple concurrent drugs taken:
  • Amlodipine
  • Nicorandil
  • Trimethoprim (200 Mg (200 Mg,unk),oral)
  • Nitroglycerin
  • Isosorbide Mononitrate
  • Simvastatin (40 Mg (40 Mg, Unk),oral)
  • Carvedilol
  • Ramipril
Patient was hospitalized.

Rhabdomyolysis, Blood Urea Increased, Angina Pectoris, Vomiting, Chromaturia, Urinary Tract Infection (7704207-7)
on Aug 04, 2011 Male from , 57 years of age, was treated with Naftidrofuryl Oxalate (naftidrofuryl Oxalate). Directly after, patient experienced the unwanted or unexpected Naftidrofuryl side effects: rhabdomyolysis, blood urea increased, angina pectoris, vomiting, chromaturia, urinary tract infection. Naftidrofuryl Oxalate (naftidrofuryl Oxalate) dosage: N/A.
Associated medications used:
  • Enoxaparin Sodium
  • Aspirin
  • Nitroglycerin
  • Ramipril
  • Simvastatin (40 Mg (40 Mg, 1 In 1 D),oral)
  • Carvedilol
  • Acetaminophen
  • Trimethoprim (200 Mg (200 Mg, 1 In 1 D),oral)
Patient was hospitalized.


Musculoskeletal Pain, Rhabdomyolysis, Urinary Tract Infection, Chromaturia, Malaise, Angina Pectoris, Vomiting, Arthralgia (7693586-5)
on Aug 02, 2011 Male from , 57 years of age, was treated with Naftidrofuryl Oxalate (naftidrofuryl Oxalate). Patient felt the following Naftidrofuryl side effects: musculoskeletal pain, rhabdomyolysis, urinary tract infection, chromaturia, malaise, angina pectoris, vomiting, arthralgia. Naftidrofuryl Oxalate (naftidrofuryl Oxalate) dosage: N/A.
Multiple prescriptions taken:
  • Glyceryl Trintrate (glyceryl Trintrate)
  • Isosorbide Mononitrate
  • Ramipril
  • Aspirin
  • Amlodipine
  • Carvedilol
  • Simvastatin (Oral)
  • Acetaminophen
Patient was hospitalized.

Haemorrhagic Stroke, Lung Infection (7641454-7)
Patient was taking Naftidrofuryl. After Naftidrofuryl was administered, patient encountered several Naftidrofuryl side effects: haemorrhagic stroke, lung infection on Jul 22, 2011 from FRANCE Additional patient health information: Male , 84 years of age, was diagnosed with
  • arterial disorder
  • hypertension
  • pain
  • depression
  • thrombosis prophylaxis
  • hypercholesterolaemia
and. Naftidrofuryl dosage: Unk.
Multiple concurrent drugs taken:
  • Micardis Hct (1 Df, 1x/day)
  • Acetaminophen (Unk)
  • Effexor Xr (75 Mg, 1x/day)
  • Plavix (Unk)
  • Crestor (10 Mg, 1x/day)
Patient was hospitalized.

Blood Creatine Phosphokinase Increased, Rhabdomyolysis (7587171-3)
Adverse event was reported on Jun 17, 2011 by a Male taking Naftidrofuryl (Dosage: 300 Mg, Unk) . Location: UNITED KINGDOM , 57 years of age, Directly after, patient experienced the unwanted or unexpected Naftidrofuryl side effects: blood creatine phosphokinase increased, rhabdomyolysis.
Associated medications used:
  • Ramipril (5 Mg, Unk)
  • Isosorbide Mononitrate (120 Mg, Unk)
  • Ranexa (Unk)
  • Aspirin (75 Mg, Unk)
  • Nitroglycerin
  • Nicorandil (60 Mg, Unk)
  • Simvastatin (40 Mg, Unk)
  • Amlodipine (10 Mg, Unk)
Patient was hospitalized.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Naftidrofuryl Information

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