Nexavar Safety Questions, Nexavar Answers
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Nexavar Safety Reports
Total Nexavar reports: 1297.Nexavar FDA safety alerts: No.
Reported deaths: 178 Reported hospitalizations: 411.
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Reported Nexavar Side Effects: fatigue, pain in extremity, diarrhoea, diarrhoea haemorrhagic, palmar-plantar erythrodysaesthesia syndrome, alopecia, blood pressure increased, nausea, anorexia, pruritus, blister.
Nexavar Usage.
Showing 1-50 of 1297 Next >
Nexavar Side Effects Report #5234210-0Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Sept 15, 2006. Male patient, 64 years of age, weighting 244.7 lb, was diagnosed with metastatic renal cell carcinoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, dyspnoea, influenza like illness. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with IMDUR, LORTAB. Patient was hospitalized. Patient recovered.
Nexavar Side Effects Report #5235189-8
NEXAVAR problem was reported by a Consumer or non-health professional from CANADA on Feb 01, 2007. Female patient, 80 years of age, was diagnosed with metastatic renal cell carcinoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: skin reaction, tooth malformation. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5237647-9
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Feb 12, 2007. Male patient, 70 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anorexia, asthenia, cholelithiasis, eructation, retching, vomiting. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with FLOMAX, AVANDIA, ZOLOFT, OXAZEPAM, PROTONIX, VYTORIN. Patient was hospitalized. Patient recovered.
Nexavar Side Effects Report #5237648-0
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 30, 2007. Male patient, 59 years of age, weighting 235.9 lb, was diagnosed with metastatic renal cell carcinoma, hypertension and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: arthralgia, back pain, blood glucose increased, blood pressure diastolic increased, bone pain, diabetes mellitus, diarrhoea, fatigue, hypertension. NEXAVAR dosage: TOTAL DAILY DOSE: 200 MG UNIT DOSE: 200 MG. During the same period patient was treated with COUMADIN, DILANTIN, ACIPHEX, HYZAAR, DEPAKOTE, FLEXERIL. Patient recovered.
Nexavar Side Effects Report #5238305-7
Consumer or non-health professional from CHINA reported NEXAVAR problem on Feb 07, 2007. Female patient, 58 years of age, was diagnosed with neoplasm malignant and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: headache, hydrocephalus, hypertension, lacunar infarction. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5238325-2
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 03, 2006. Female patient, 84 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: chest discomfort, heart rate increased, heart rate irregular. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. Patient recovered.
Nexavar Side Effects Report #5239359-4
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Feb 12, 2007. Male patient, 52 years of age, weighting 141.1 lb, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, erythema, fatigue, hyperkeratosis, rash, temperature intolerance, weight decreased. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. Patient recovered.
Nexavar Side Effects Report #5240316-2
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 13, 2007. Male patient, 52 years of age, weighting 143.3 lb, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: abdominal pain, blister, cellulitis, constipation, diarrhoea, epistaxis, fatigue, metastases to lymph nodes, oedema peripheral. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. Patient was hospitalized. Patient recovered.
Nexavar Side Effects Report #5240324-1
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Feb 13, 2007. Male patient, weighting 145.5 lb, was diagnosed with hepatic neoplasm malignant and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: asthenia, dehydration, dry skin, gingival bleeding, lethargy, nausea, platelet count abnormal, vomiting. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with MORPHINE, DILAUDID, HYZAAR, METFORMIN, GLUCOPHAGE, LEXAPRO. Patient recovered.
Nexavar Side Effects Report #5241331-5
NEXAVAR problem was reported by a Consumer or non-health professional from CANADA on Feb 16, 2007. Male patient, 36 years of age, was diagnosed with metastatic renal cell carcinoma and was treated with NEXAVAR. NEXAVAR dosage: unknown. Patient died on 02/15/2007.
Nexavar Side Effects Report #5241377-7
Physician from NETHERLANDS reported NEXAVAR problem on Feb 15, 2007. Male patient, 67 years of age, was diagnosed with clear cell carcinoma of the kidney and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: alopecia, blister, chest discomfort, chest pain, nausea, rash vesicular, syncope. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG. During the same period patient was treated with SELOKEEN, ZOCOR. Patient recovered.
Nexavar Side Effects Report #5241394-7
NEXAVAR problem was reported by a Physician from CANADA on Feb 13, 2007. Male patient, 81 years of age, was diagnosed with metastatic renal cell carcinoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: burning sensation, electrocardiogram t wave inversion, palpitations. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG. Patient recovered.
Nexavar Side Effects Report #5242478-X
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Feb 13, 2007. Male patient, 64 years of age, weighting 244.7 lb, was diagnosed with metastatic renal cell carcinoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, dyspnoea, influenza like illness. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with IMDUR, LORTAB. Patient was hospitalized. Patient recovered.
Nexavar Side Effects Report #5242514-0
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 12, 2007. Male patient, 64 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: post procedural infection, skin cancer. NEXAVAR dosage: AS USED: 400/200 MG UNIT DOSE: 200 MG. Patient recovered.
Nexavar Side Effects Report #5243728-6
Health Professional from UNITED STATES reported NEXAVAR problem on Feb 13, 2007. Female patient was diagnosed with thyroid cancer and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: cardiac failure congestive, lung neoplasm. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with SYNTHROID. Patient was hospitalized. Patient recovered.
Nexavar Side Effects Report #5243738-9
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 20, 2007. Female patient, 80 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident, rash, stomatitis. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5245043-3
Health Professional from UNITED STATES reported NEXAVAR problem on Jan 31, 2007. Male patient, 74 years of age, was diagnosed with lung cancer metastatic and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: keratoacanthoma. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG. Patient recovered.
Nexavar Side Effects Report #5245044-5
NEXAVAR problem was reported by a Health Professional from UNITED STATES on Jan 31, 2007. Male patient, 65 years of age, was diagnosed with prostate cancer metastatic and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: fatigue, keratoacanthoma, neuropathy. NEXAVAR dosage: TOTAL DAILY DOSE: 400 MG. Patient recovered.
Nexavar Side Effects Report #5245050-0
Health Professional from UNITED STATES reported NEXAVAR problem on Jan 31, 2007. Female patient, 63 years of age, was diagnosed with leiomyosarcoma metastatic and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: keratoacanthoma, leiomyosarcoma metastatic, malignant neoplasm progression. NEXAVAR dosage: TOTAL DAILY DOSE: 400 MG. Patient recovered.
Nexavar Side Effects Report #5246530-4
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 20, 2007. Male patient, 78 years of age, weighting 149.9 lb, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: oedema, rash. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. Patient was hospitalized and became disabled. Patient recovered.
Nexavar Side Effects Report #5246552-3
Health Professional from UNITED STATES reported NEXAVAR problem on Feb 20, 2007. Male patient, 71 years of age, was diagnosed with malignant melanoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: amnesia, colon cancer, constipation, fatigue, growth retardation, hepatic lesion, impaired healing, lymphadenopathy, metastases to liver. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with METHADONE, VICODIN, VALIUM. Patient was hospitalized. Patient died on 09/02/2006.
Nexavar Side Effects Report #5246564-X
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 12, 2007. Male patient, 64 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: post procedural infection, skin cancer. NEXAVAR dosage: AS USED: 400/200 MG UNIT DOSE: 200 MG. Patient recovered.
Nexavar Side Effects Report #5246565-1
Physician from UNITED STATES reported NEXAVAR problem on Feb 07, 2007. Female patient, 68 years of age, weighting 127.9 lb, was diagnosed with essential thrombocythaemia and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: abdominal pain, alopecia, anorexia, arthralgia, asthenia, chills, diarrhoea, erythema, eye inflammation. NEXAVAR dosage: TOTAL DAILY DOSE: 200 MG UNIT DOSE: 200 MG. During the same period patient was treated with HYDREA. Patient recovered.
Nexavar Side Effects Report #5247364-7
NEXAVAR problem was reported by a Consumer or non-health professional from CANADA on Feb 22, 2007. Female patient, 69 years of age, was treated with NEXAVAR. NEXAVAR dosage: unknown. Patient died on 01/18/2007.
Nexavar Side Effects Report #5247389-1
Health Professional from UNITED STATES reported NEXAVAR problem on Feb 21, 2007. Female patient, 66 years of age, weighting 183.0 lb, was diagnosed with metastatic renal cell carcinoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: ascites, dyspnoea, hyperkalaemia, myocardial infarction, nephrotic syndrome, rash, troponin increased, weight increased. NEXAVAR dosage: TOTAL DAILY DOSE: 400 MG UNIT DOSE: 200 MG. During the same period patient was treated with AMARYL, ASPIRIN, COZAAR, GLUCOPHAGE, LASIX, TRICOR. Patient was hospitalized. Patient recovered.
Nexavar Side Effects Report #5247432-X
NEXAVAR problem was reported by a Health Professional from UNITED STATES on Jan 31, 2007. Male patient, 65 years of age, was diagnosed with prostate cancer metastatic and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: fatigue, keratoacanthoma, neuropathy. NEXAVAR dosage: TOTAL DAILY DOSE: 400 MG. Patient recovered.
Nexavar Side Effects Report #5247433-1
Health Professional from UNITED STATES reported NEXAVAR problem on Jan 31, 2007. Female patient, 63 years of age, was diagnosed with leiomyosarcoma metastatic and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: keratoacanthoma, leiomyosarcoma metastatic. NEXAVAR dosage: TOTAL DAILY DOSE: 400 MG. Patient recovered.
Nexavar Side Effects Report #5247465-3
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 19, 2007. Male patient, 52 years of age, weighting 141.1 lb, was diagnosed with metastatic renal cell carcinoma, back injury, chronic obstructive pulmonary disease and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: erythema, fatigue, hair growth abnormal, hyperkeratosis, hypotension, rash, temperature regulation disorder, weight decreased. NEXAVAR dosage: TOTAL DAILY DOSE: 800 MG UNIT DOSE: 200 MG. During the same period patient was treated with DILANTIN, PAXIL, FENTANYL TRANSDERMAL SYSTEM, SPIRIVA. Patient recovered.
Nexavar Side Effects Report #5248695-7
Physician from UNITED STATES reported NEXAVAR problem on Feb 07, 2007. Female patient, 68 years of age, weighting 127.9 lb, was diagnosed with essential thrombocythaemia and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: abdominal pain, alopecia, anorexia, arthralgia, asthenia, chills, diarrhoea, erythema, eye inflammation. NEXAVAR dosage: TOTAL DAILY DOSE: 200 MG UNIT DOSE: 200 MG. During the same period patient was treated with HYDREA. Patient recovered.
Nexavar Side Effects Report #5321017-9
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 20, 2006. Male patient, 51 years of age, weighting 235.0 lb, was diagnosed with metastatic renal cell carcinoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blister, pain of skin, rash, skin discolouration, skin swelling, tenderness. NEXAVAR dosage: 400 MG, BID, ORAL. Patient recovered.
Nexavar Side Effects Report #5321024-6
Pharmacist from UNITED STATES reported NEXAVAR problem on Nov 14, 2006. Male patient, 76 years of age, weighting 125.0 lb, was diagnosed with neoplasm malignant and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: anorexia, cough, diarrhoea haemorrhagic, dry skin, fatigue, feeling hot and cold, myalgia, nausea, pain of skin. NEXAVAR dosage: 400 MG, BID, ORAL. During the same period patient was treated with COUMADIN, FLOMAX, VITAMINS, ZESTRIL. Patient recovered.
Nexavar Side Effects Report #5321025-8
NEXAVAR problem was reported by a Pharmacist from UNITED STATES on Oct 23, 2006. Female patient, 65 years of age, weighting 147.0 lb, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, constipation, decreased appetite, erythema, hepatic enzyme increased, influenza like illness, pain in extremity, palmar-plantar erythrodysaesthesia syndrome, pyrexia. NEXAVAR dosage: unknown. During the same period patient was treated with ACTONEL. Patient recovered.
Nexavar Side Effects Report #5321070-2
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Nov 30, 2006. Male patient was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, dizziness, dry skin, headache, nausea, pruritus. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5321072-6
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 04, 2006. Male patient was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: stomach discomfort. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5321084-2
Pharmacist from UNITED STATES reported NEXAVAR problem on Nov 16, 2006. Male patient, 66 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: pruritus, rash, skin exfoliation. NEXAVAR dosage: 400 MG, BID, ORAL. Patient recovered.
Nexavar Side Effects Report #5321085-4
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 01, 2006. Female patient was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blister, decreased appetite. NEXAVAR dosage: unknown. During the same period patient was treated with PAIN PATCH, OXYCODONE, LASIX. Patient recovered.
Nexavar Side Effects Report #5321087-8
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Dec 05, 2006. Male patient was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: rash. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5321092-1
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 08, 2006. Male patient, 66 years of age, was diagnosed with hepatic neoplasm malignant and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blister, fatigue, libido decreased. NEXAVAR dosage: unknown. During the same period patient was treated with LORTAB. Patient recovered.
Nexavar Side Effects Report #5321180-X
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Apr 18, 2006. Male patient, 53 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: skin burning sensation. NEXAVAR dosage: 400 MG, BID, ORAL. During the same period patient was treated with BENADRYL, VICODIN. Patient recovered.
Nexavar Side Effects Report #5321181-1
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on June 28, 2006. Male patient, 49 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blister, pain in extremity. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5321188-4
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Aug 08, 2006. Male patient, weighting 120.0 lb, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: alopecia, decreased appetite, pruritus, rash, skin exfoliation, swelling face. NEXAVAR dosage: 600 MG, TOTAL DAILY, ORAL. Patient recovered.
Nexavar Side Effects Report #5321199-9
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 23, 2007. Male patient, 62 years of age, was diagnosed with malignant melanoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blister, diarrhoea, flatulence, hypertension, palmar-plantar erythrodysaesthesia syndrome. NEXAVAR dosage: 400 MG, BID, ORAL. Patient recovered.
Nexavar Side Effects Report #5321200-2
Health Professional from UNITED STATES reported NEXAVAR problem on Sept 19, 2006. Male patient, 63 years of age, was diagnosed with multiple myeloma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: frequent bowel movements. NEXAVAR dosage: 400 MG, BID, ORAL. Patient recovered.
Nexavar Side Effects Report #5321202-6
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 18, 2006. Female patient was diagnosed with non-small cell lung cancer and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: unevaluable event. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5321203-8
Health Professional from UNITED STATES reported NEXAVAR problem on Sept 18, 2006. Female patient, 46 years of age, was diagnosed with ovarian cancer and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: acne, arthralgia, back pain, blood pressure increased, dysphonia, hypoaesthesia, myalgia, paraesthesia. NEXAVAR dosage: unknown. During the same period patient was treated with HYCAMPTIN, PROTONIX, SUPPLEMENTAL IRON. Patient recovered.
Nexavar Side Effects Report #5321205-1
NEXAVAR problem was reported by a Health Professional from UNITED STATES on Sept 21, 2006. Female patient was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: diarrhoea. NEXAVAR dosage: unknown. Patient recovered.
Nexavar Side Effects Report #5321207-5
Pharmacist from UNITED STATES reported NEXAVAR problem on Sept 23, 2006. Male patient, 57 years of age, was diagnosed with neoplasm malignant and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: alopecia. NEXAVAR dosage: 400 MG, BID, ORAL. Patient recovered.
Nexavar Side Effects Report #5321208-7
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 25, 2006. Male patient, 78 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: blood pressure increased, diarrhoea, dysphonia, muscle spasms, pain in extremity. NEXAVAR dosage: unknown. During the same period patient was treated with NORVASC, BENICAR, SELENIUM SULFIDE, VITAMIN B, GARLIC, ASPIRIN. Patient recovered.
Nexavar Side Effects Report #5321221-X
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Dec 11, 2006. Male patient, 83 years of age, was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: rash macular, rash pruritic. NEXAVAR dosage: 400 MG, BID, ORAL. Patient recovered.
Nexavar Side Effects Report #5321222-1
NEXAVAR problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 12, 2006. Male patient was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: stomatitis, tongue ulceration. NEXAVAR dosage: unknown. Patient recovered.
Showing 1-50 of 1297 Next >
Drug Information: Sorafenib
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607051.html
soe raf' e nibWhy is this medication prescribed?
Sorafenib is used to treat advanced renal cell carcinoma (a type of cancer that begins in the kidneys). Sorafenib is in a class of medications called multikinase inhibitors. It works by slowing the spread of cancer cells.
How should this medicine be used?
Sorafenib comes as a tablet to take by mouth. It is usually taken twice a day. Sorafenib is taken without food, one hour before or 2 hours after a meal. Take sorafenib at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sorafenib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the tablets whole with water. Do not split, chew, or crush them.
Your doctor may decrease your dose of sorafenib during your treatment, or may tell you to stop taking sorafenib for a period of time if you experience side effects. Be sure to tell your doctor how you are feeling during your treatment with sorafenib.
Continue to take sorafenib even if you feel well. Do not stop taking sorafenib without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking sorafenib,
- tell your doctor and pharmacist if you are allergic to sorafenib or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants (blood thinners) such as warfarin (Coumadin), bupropion (Wellbutrin, Zyban), carbamazepine (Equetro, Tegretol), cyclophosphamide (Cytoxan, Neosar), dexamethasone, doxorubicin (Doxil, Adriamycin), efavirenz (Sustiva), ifosfamide, irinotecan (Camptosar), methadone (Dolophine, Methadose), phenobarbital, phenytoin (Dilantin, Phenytek), or rifampin (Rifadin, Rimactane). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you have or have ever had high blood pressure, bleeding problems, chest pain, a heart attack, kidney disease other than kidney cancer, or heart or liver disease.
- you should know that sorafenib may decrease fertility in men and women. However, you should not assume that you or your partner cannot become pregnant. If you are pregnant or breastfeeding, you should tell your doctor before you begin taking this drug. Use a reliable method of birth control during your treatment and for 2 weeks after you stop taking sorafenib. Talk to your doctor about birth control methods that will work for you. Sorafenib may harm the fetus.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking sorafenib.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Sorafenib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- tiredness
- weakness
- rash
- skin redness
- hair loss
- itching
- dry skin
- nausea
- vomiting
- loss of appetite
- constipation
- diarrhea
- stomach pain
- dry mouth
- mouth sores
- weight loss
- joint pain
- numbness, pain or tingling in hands or feet
- headache
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- unusual bruising or bleeding
- black and/or tarry stools
- red blood in stools
- bloody vomit
- vomiting material that looks like coffee grounds
- severe abdominal pain
- chest pain
- shortness of breath
- sudden severe headache
- confusion
- changes in vision
- seizures
- redness, pain, swelling or blisters on the palms of the hands or soles of the feet
Sorafenib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- diarrhea
- rash or other skin problems
What other information should I know?
Keep all appointments with your doctor. Your doctor will check your blood pressure every week during the first six weeks of your treatment and then from time to time as needed.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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