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Psoriasis (3)
High Blood Pressure (1)
Light Headedness (1)
Urticaria (1)
Hepartoxicity (1)
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Nimesulide Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 36 

Confusional State, Inadequate Diet, Pruritus, Erythema (8433432-5)
on Jun 04, 2012 Female from BRAZIL , 55 years of age, weighting 165.3 lb, was diagnosed with
  • osteoarthritis
  • arthralgia
and was treated with Nimesulide. Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: confusional state, inadequate diet, pruritus, erythema. Nimesulide dosage: N/A.
Associated medications used:
  • Acetaminophen W/ Codeine
  • Dipyrone Tab


Prostatic Disorder, Hearing Impaired (8421530-1)
Patient was taking Nimesulide. Patient felt the following Nimesulide side effects: prostatic disorder, hearing impaired on May 30, 2012 from BRAZIL Additional patient health information: Male , weighting 134.5 lb, was diagnosed with
  • rheumatoid arthritis
and. Nimesulide dosage: N/A.
Multiple prescriptions taken:
  • Remicade
  • Ranitidine
  • Hydroxychloroquine Sulfate
  • Methotrexate
  • Prednisone Tab
  • Remicade


Uterine Disorder (8345820-6)
Adverse event was reported on Apr 27, 2012 by a Female taking Nimesulide (Dosage: Unk) . Location: BRAZIL , weighting 147.7 lb, After Nimesulide was administered, patient encountered several Nimesulide side effects: uterine disorder.
Multiple concurrent drugs taken:
  • Prednisone Tab (Unk)
  • Enbrel (Unk)


Nephrolithiasis, Walking Disability, Injection Site Discolouration, Renal Cyst, Arthropathy, Pain (8229860-3)
on Mar 13, 2012 Female from BRAZIL , weighting 183.0 lb, was treated with Nimesulide. Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: nephrolithiasis, walking disability, injection site discolouration, renal cyst, arthropathy, pain. Nimesulide dosage: Unk.
Associated medications used:
  • Enbrel (50 Mg, Weekly,powder And Solvent For Solution For Injection)
  • Captopril (25 Mg, Unk)
  • Methotrexate (Unk)
  • Cyclobenzaprine Hcl (Unk)
  • Sodium Carbonate (Unk)
  • Enbrel (Unk,solution For Injection In Pre-filled Pen)
  • Metformin Hcl (850 Mg, Unk)
  • Aspirin (100 Mg, Unk)



Somnolence, Muscle Fatigue, Malaise, Wound, Nausea, Arthropathy, Asthenia, Nasopharyngitis, Blood Cholesterol Increased (8164181-9)
on Feb 15, 2012 Female from BRAZIL , weighting 103.6 lb, was diagnosed with
  • inflammation
  • osteoarthritis
and was treated with Nimesulide. Patient felt the following Nimesulide side effects: somnolence, muscle fatigue, malaise, wound, nausea, arthropathy, asthenia, nasopharyngitis, blood cholesterol increased. Nimesulide dosage: N/A.
Multiple prescriptions taken:
  • Sodium Chloride
  • Humira
  • Synthroid
  • Risedronate Sodium
  • Arava
  • Humira
  • Calcium Phosphate W/colecalciferol (400/600 Mg)
  • Deflazacort


Arthritis, Osteoarthritis, Joint Effusion, Synovitis, Female Sterilisation, Foreign Body, Postoperative Wound Infection, Purulent Discharge (8142623-2)
Patient was taking Nimesulide. After Nimesulide was administered, patient encountered several Nimesulide side effects: arthritis, osteoarthritis, joint effusion, synovitis, female sterilisation, foreign body, postoperative wound infection, purulent discharge on Feb 09, 2012 from BRAZIL Additional patient health information: Female , weighting 180.8 lb, . Nimesulide dosage: N/A.
Multiple concurrent drugs taken:
  • Prednisone Tab
  • Cyclobenzaprine
  • Humira
  • Cyclobenzaprine
  • Arava
  • Arava
  • Tramadol Hydrochloride
  • Fluoxetine


Road Traffic Accident, Skin Graft, Extremity Necrosis (8078319-5)
Adverse event was reported on Jan 12, 2012 by a Female taking Nimesulide (nimesulide) (nimesulide) (Dosage: 200 Mg (100 Mg, 2 In 1 D), Per Oral) was diagnosed with
  • extremity necrosis
  • hypertension
and. Location: BRAZIL , 61 years of age, Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: road traffic accident, skin graft, extremity necrosis.
Associated medications used:
  • Benicar (20 Mg (20 Mg, 1 In 1 D), Per Oral, 40 Mg (40 Mg, 1 In 1 D), Per Oral)
  • Benicar (20 Mg (20 Mg, 1 In 1 D), Per Oral, 40 Mg (40 Mg, 1 In 1 D), Per Oral)
  • Cephalexin (2000 Mg (500 Mg, 4 In 1 D), Per Oral)
Patient was hospitalized.

Renal Failure Acute, Osteomyelitis, Nephritic Syndrome (8064410-6)
on Jan 19, 2012 Male from ITALY , 57 years of age, was treated with Nimesulide. Patient felt the following Nimesulide side effects: renal failure acute, osteomyelitis, nephritic syndrome. Nimesulide dosage: N/A.
Multiple prescriptions taken:
  • Tizanidine Hcl
  • Cubicin
  • Ramipril
Patient was hospitalized.

Oedema Peripheral, Rheumatoid Arthritis, Joint Prosthesis User, Joint Swelling (8048083-4)
on Jan 09, 2012 Female from BRAZIL , 43 years of age, weighting 172.0 lb, was treated with Nimesulide. After Nimesulide was administered, patient encountered several Nimesulide side effects: oedema peripheral, rheumatoid arthritis, joint prosthesis user, joint swelling. Nimesulide dosage: Unk.
Multiple concurrent drugs taken:
  • Enbrel (50 Mg, Weekly)
  • Pantoprazole (Unk)
  • Prednisone (Unk)
  • Methotrexate (Unk)
  • Propan (Unk)


Pyrexia, Laryngitis, Osteoarthritis, Pharyngitis, Anaemia, Weight Decreased, Mass (7995384-1)
Patient was taking Nimesulide. Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: pyrexia, laryngitis, osteoarthritis, pharyngitis, anaemia, weight decreased, mass on Dec 16, 2011 from BRAZIL Additional patient health information: Female , weighting 172.0 lb, was diagnosed with
  • rheumatoid arthritis
and. Nimesulide dosage: N/A.
Associated medications used:
  • Deflazacort
  • Humira
  • Glucosamine
Patient was hospitalized.

Gastritis Erosive, Gastrointestinal Erosion, Erosive Duodenitis (7965078-7)
Adverse event was reported on Nov 30, 2011 by a Male taking Nimesulide (Dosage: N/A) . Location: RUSSIAN FEDERATION , weighting 205.0 lb, Patient felt the following Nimesulide side effects: gastritis erosive, gastrointestinal erosion, erosive duodenitis.
Multiple prescriptions taken:
  • Actemra
  • Actemra (Dosage From Reported As Flacon.)
  • Ranitidine Hcl
  • Chloroquine
Patient was hospitalized.

Bladder Transitional Cell Carcinoma (7957250-7)
on Nov 15, 2011 Male from CZECH REPUBLIC , 68 years of age, was treated with Nimesulide. After Nimesulide was administered, patient encountered several Nimesulide side effects: bladder transitional cell carcinoma. Nimesulide dosage: N/A.
Multiple concurrent drugs taken:
  • Losartan Potassium
  • Hydrochlorothiazide
  • Ibuprofen
  • Vildagliptin
  • Acetaminophen
  • Actos (30 Mg (30 Mg, 1 In 1 D), Per Oral)
  • Omeprazole
  • Diclophenac (diclofenac Sodium)
Patient was hospitalized.

Anal Fistula, Haemorrhoids (7829159-0)
on Oct 12, 2011 Female from BRAZIL , weighting 253.5 lb, was diagnosed with
  • inflammation
  • hypertension
  • pain
  • functional gastrointestinal disorder
and was treated with Nimesulide. Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: anal fistula, haemorrhoids. Nimesulide dosage: 1 Df, Every 8 Hour.
Associated medications used:
  • Exforge (1 Df, Qd (160 Mg Vals And 5 Mg Amlo))
  • Acetaminophen W/ Codeine (1 Df, Unk)
  • Plantago Ovata Husk (1 Df (1 Sachet Before Sleep))
Patient was hospitalized.

Decreased Appetite, Weight Decreased, Dyspepsia, Alanine Aminotransferase Increased, Immunoglobulins Abnormal (7827241-5)
Patient was taking Nimesulide. Patient felt the following Nimesulide side effects: decreased appetite, weight decreased, dyspepsia, alanine aminotransferase increased, immunoglobulins abnormal on Oct 13, 2011 from ITALY Additional patient health information: Female , 86 years of age, was diagnosed with
  • osteoarthritis
  • coronary artery disease
  • goitre
and. Nimesulide dosage: 100 Mg, As Needed.
Multiple prescriptions taken:
  • Atorvastatin Calcium (20 Mg, Daily)
  • Tapazole (5 Mg, Weekly)
Patient was hospitalized.

Hypersensitivity, Tongue Oedema, Presyncope, Abdominal Pain Upper, Infusion Related Reaction (7826552-7)
Adverse event was reported on Oct 10, 2011 by a Female taking Nimesulide (Dosage: N/A) . Location: ITALY , 52 years of age, After Nimesulide was administered, patient encountered several Nimesulide side effects: hypersensitivity, tongue oedema, presyncope, abdominal pain upper, infusion related reaction.
Multiple concurrent drugs taken:
  • Methylprednisolone
  • Plaquenil
  • Ranidil
  • Medrol
  • Remicade


Vascular Anomaly, Pain In Extremity, Hypertension (7743077-8)
on Sep 02, 2011 Female from BRAZIL , weighting 183.0 lb, was treated with Nimesulide. Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: vascular anomaly, pain in extremity, hypertension. Nimesulide dosage: N/A.
Associated medications used:
  • Tocilizumab (Form: Infusion)
  • Prednisone (Brand: Meticorten)
  • Omeprazole
  • Losartan Potassium
Patient was hospitalized.

Tenosynovitis, Arthritis Reactive, Benign Soft Tissue Neoplasm (7575589-4)
on Jun 15, 2011 Male from UKRAINE , weighting 187.4 lb, was diagnosed with
  • arthralgia
  • crohn's disease
and was treated with Nimesulide. Patient felt the following Nimesulide side effects: tenosynovitis, arthritis reactive, benign soft tissue neoplasm. Nimesulide dosage: N/A.
Multiple prescriptions taken:
  • Certolizumab Pegol (C87085)
  • Certolizumab Pegol
  • Certolizumab Pegol (At 0, 2 And 4 Weeks)
Patient was hospitalized.

Erythema Nodosum (7492845-9)
Patient was taking Nimesulide. After Nimesulide was administered, patient encountered several Nimesulide side effects: erythema nodosum on May 06, 2011 from ITALY Additional patient health information: Female , 25 years of age, . Nimesulide dosage: N/A.

Rheumatoid Arthritis, Duodenal Ulcer Haemorrhage, Lung Disorder, Pneumonia, Pyrexia (7399477-1)
Adverse event was reported on Apr 01, 2011 by a Male taking Nimesulide (Dosage: 100 Mg, Bid) was diagnosed with
  • rheumatoid arthritis
and. Location: UNITED STATES , 48 years of age, weighting 156.5 lb, Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: rheumatoid arthritis, duodenal ulcer haemorrhage, lung disorder, pneumonia, pyrexia.
Associated medications used:
  • Methotrexat
  • Metypred ^orion^
  • Folic Acid
  • Diclofenac (75 Mg, Qd)
  • Meloxicam
Patient was hospitalized.

Neck Pain, Myocardial Infarction, Malaise, Arthropathy, Weight Increased, Headache, Fatigue, Nasal Congestion, Groin Pain (7382050-9)
on Mar 16, 2011 Male from UNITED KINGDOM , weighting 205.0 lb, was treated with Nimesulide. Patient felt the following Nimesulide side effects: neck pain, myocardial infarction, malaise, arthropathy, weight increased, headache, fatigue, nasal congestion, groin pain. Nimesulide dosage: 100 Mg, Unk.
Multiple prescriptions taken:
  • Biofenac (aceclofenac) (100 Mg, Unk)
  • Tylex (30 Mg, Unk)
  • Tandrilax (Unk)
  • Cipro (500 Mg, Unk)
  • Captopril (25 Mg, Unk)
  • Tramal (50 Mg, Unk)
  • Rituximab (500 Mg/ml, Q14d)
Patient was hospitalized.

Osteoporosis, Bone Erosion, Procedural Pain, Blood Cholesterol Increased, Anaemia, Pain In Extremity, Tachycardia (7275400-5)
on Feb 03, 2011 Female from BRAZIL , weighting 134.5 lb, was diagnosed with
  • arthralgia
  • rheumatoid arthritis
  • hypertension
and was treated with Nimesulide. After Nimesulide was administered, patient encountered several Nimesulide side effects: osteoporosis, bone erosion, procedural pain, blood cholesterol increased, anaemia, pain in extremity, tachycardia. Nimesulide dosage: N/A.
Multiple concurrent drugs taken:
  • Diclofenac Sodium
  • Moduretic 5-50
  • Methotrexate
  • Humira
  • Prednisone
  • Zexin
Patient was hospitalized.

Oedema, Abdominal Distension, Hypertension, Malaise, Blister, Bursitis, Tendon Disorder, Antinuclear Antibody, Myalgia (7251516-4)
Patient was taking Nimesulide. Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: oedema, abdominal distension, hypertension, malaise, blister, bursitis, tendon disorder, antinuclear antibody, myalgia on Jan 17, 2011 from UNITED KINGDOM Additional patient health information: Female , weighting 149.9 lb, . Nimesulide dosage: 100 Mg, Unk.
Associated medications used:
  • Beserol (100 Mg, Q12h)
  • Rituximab (1000 Mg, Q15d)
  • Calcort (6 Mg, Q6h)
  • Dorflex (100 Mg, Unk)
  • Prednisone (Unk)
  • Captopril (25 Mg, Unk)
  • Miosan (5 Mg, Unk)
  • Omeprazole (20 Mg, Unk)


Dyspnoea, Chest Discomfort, Deformity, Hyperhidrosis, Feeling Hot, Hair Disorder, Swelling, Oropharyngeal Pain (7233298-5)
Adverse event was reported on Jan 14, 2011 by a Female taking Nimesulide (Dosage: N/A) was diagnosed with
  • rheumatoid arthritis
and. Location: BRAZIL , weighting 176.4 lb, Patient felt the following Nimesulide side effects: dyspnoea, chest discomfort, deformity, hyperhidrosis, feeling hot, hair disorder, swelling, oropharyngeal pain.
Multiple prescriptions taken:
  • Paracetamol
  • Actemra (Freq: 5 Ampoules/month, Missed One Dose In December)
  • Deflazacort
  • Amytril (Taken When Presents Pain)
  • Ranitidine
  • Dipyrone


Erythema (6614913-3)
on Feb 21, 2010 Female from ITALY , 49 years of age, was treated with Nimesulide. After Nimesulide was administered, patient encountered several Nimesulide side effects: erythema. Nimesulide dosage: N/A.
Multiple concurrent drugs taken:
  • Paracetamol
Patient was hospitalized.

Acute Hepatic Failure, Hepatotoxicity, Multi-organ Failure (5964576-5)
on Nov 04, 2008 Female from IRELAND , 61 years of age, was treated with Nimesulide (nimesulide). Directly after, patient experienced the unwanted or unexpected Nimesulide side effects: acute hepatic failure, hepatotoxicity, multi-organ failure. Nimesulide (nimesulide) dosage: N/A.
Associated medications used:
  • Fluoxetine
  • Aspirin
  • Valsartan And Hydrochlorothiazide
  • Nebivolol Hcl
  • Levothyroxine Sodium


Showing 1-25 of 36 

Nimesulide Health Episodes

How Can Nimesulide Affect You?

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Nimesulide Information

More About Nimesulide

Side Effects reported to FDA: 36. View Nimesulide Adverse Reports

Nimesulide safety alerts: No

Reported deaths: 3

Reported hospitalizations: 15

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