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Nitrofur Side Effects

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Common Nitrofur Side Effects


The most commonly reported Nitrofur side effects (click to view or check a box to report):

Dyspnoea (95)
Nausea (90)
Chills (87)
Headache (80)
Pyrexia (75)
Vomiting (61)
Asthenia (60)
Malaise (50)
Pain (50)
Cough (50)
Chest Pain (48)
Dizziness (48)
Fatigue (48)
Diarrhoea (41)
Rash (40)
Arthralgia (38)
Pruritus (33)
Myalgia (31)
Oedema Peripheral (31)
Pulmonary Fibrosis (30)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Nitrofur Side Effects Reported to FDA



Nitrofur Side Effect Report#9971415
Diarrhoea, Vomiting, Pyrexia, Chills, Lung Disorder, Lupus-like Syndrome, Interstitial Lung Disease, Antibody Test Positive, Dyspnoea
This is a report of a 50-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: prophylaxis urinary tract infection,bladder operation, who was treated with Nitrofurantoin Macrocrystals (dosage: 100 Mg/1 Pill Once Daily Taken By Mouth, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Diarrhoea, Vomiting, Pyrexia, Chills, Lung Disorder, Lupus-like Syndrome, Interstitial Lung Disease, Antibody Test Positive, Dyspnoea after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Nitrofurantoin Macrocrystals treatment in female patients, resulting in Diarrhoea side effect. The patient was hospitalized and became disabled.
Nitrofur Side Effect Report#9971379
Nausea, Pruritus, Pruritus, Pruritus, Urticaria, Eye Pruritus, Hypopnoea, Dizziness
This report suggests a potential Nitrofurantoin Nausea side effect(s) that can have serious consequences. A 48-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: urinary tract infection and used Nitrofurantoin (dosage: NA) starting
Mar 03, 2014. After starting Nitrofurantoin the patient began experiencing various side effects, including: Nausea, Pruritus, Pruritus, Pruritus, Urticaria, Eye Pruritus, Hypopnoea, DizzinessAdditional drugs used concurrently: NA. Although Nitrofurantoin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Nausea, may still occur.
Nitrofur Side Effect Report#9954041
Interstitial Lung Disease, Leukocytosis, Lymphopenia, Blood Lactate Dehydrogenase
This Interstitial Lung Disease problem was reported by a physician from DE. A 40-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: cystitis noninfective. On
Feb 09, 2014 this consumer started treatment with Nitrofurantoinum (dosage: 2 Dosage Forms Daily;). The following drugs were being taken at the same time: NA. When using Nitrofurantoinum, the patient experienced the following unwanted symptoms/side effects: Interstitial Lung Disease, Leukocytosis, Lymphopenia, Blood Lactate DehydrogenaseAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Interstitial Lung Disease, may become evident only after a product is in use by the general population.
Nitrofur Side Effect Report#9940524
Acute Respiratory Distress Syndrome, Maternal Exposure During Pregnancy
This Acute Respiratory Distress Syndrome side effect was reported by a health professional from EG. A 23-year-old female patient (weight:NA) experienced the following symptoms/conditions: urinary tract infection.The patient was prescribed Nitrofurantoin (drug dosage: NA), which was initiated on NS. Concurrently used drugs: NA..After starting to take Nitrofurantoin the consumer reported adverse symptoms, such as: Acute Respiratory Distress Syndrome, Maternal Exposure During PregnancyThese side effects may potentially be related to Nitrofurantoin. The patient was hospitalized.
Nitrofur Side Effect Report#9931991
Local Swelling, Pain In Extremity, Arthralgia, Joint Swelling
This is a report of a 73-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Nitrofurantoin Monohydrate (dosage: NA, start time:
Jan 28, 2014), combined with:
  • Simvastatin
  • Prednisone
  • Atenolol
  • Levothroxin
  • Aspirin
  • Vit E
  • Co Q10
  • Potassium
and developed a serious reaction and side effect(s): Local Swelling, Pain In Extremity, Arthralgia, Joint Swelling after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Nitrofurantoin Monohydrate treatment in female patients, resulting in Local Swelling side effect.
Nitrofur Side Effect Report#9931797
Oral Herpes, Pain
This report suggests a potential Nitrofurantoin Oral Herpes side effect(s) that can have serious consequences. A 50-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: cystitis and used Nitrofurantoin (dosage: NA) starting
Jan 06, 2014. After starting Nitrofurantoin the patient began experiencing various side effects, including: Oral Herpes, PainAdditional drugs used concurrently: NA. Although Nitrofurantoin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Oral Herpes, may still occur.
Nitrofur Side Effect Report#9928648
Respiratory Failure, Acute Respiratory Distress Syndrome, Dyspnoea, Tachypnoea, Cough, End-tidal Co2 Decreased, Oxygen Saturation Decreased, Breath Sounds Abnormal, Hypocapnia
This Respiratory Failure problem was reported by a health professional from EG. A 23-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection,prophylaxis. On NS this consumer started treatment with Nitrofurantoin (dosage: 1 Df, Bid). The following drugs were being taken at the same time:
  • Enoxaparin Sodium (40 Mg, Unk)
  • Remifentanil (0.1 Ug/kg/min)
  • Propofol (50 Mg/hour)
  • Methylprednisolone (1 Mg/kg/day)
When using Nitrofurantoin, the patient experienced the following unwanted symptoms/side effects: Respiratory Failure, Acute Respiratory Distress Syndrome, Dyspnoea, Tachypnoea, Cough, End-tidal Co2 Decreased, Oxygen Saturation Decreased, Breath Sounds Abnormal, HypocapniaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Respiratory Failure, may become evident only after a product is in use by the general population.
Nitrofur Side Effect Report#9874771
Pneumonia
This Pneumonia side effect was reported by a consumer or non-health professional from US. A 81-year-old female patient (weight:NA) experienced the following symptoms/conditions: cystitis.The patient was prescribed Nitrofurantoin Macro (drug dosage: NA), which was initiated on
Sep 08, 2011. Concurrently used drugs: NA..After starting to take Nitrofurantoin Macro the consumer reported adverse symptoms, such as: PneumoniaThese side effects may potentially be related to Nitrofurantoin Macro. The patient was hospitalized.
Nitrofur Side Effect Report#9859077
Rash, Back Pain, Oliguria, Prurigo, Macule, Erythema, Hypotension, Pyrexia
This is a report of a 77-year-old female patient (weight: NA) from PT, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Nitrofurantoin (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Rash, Back Pain, Oliguria, Prurigo, Macule, Erythema, Hypotension, Pyrexia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Nitrofurantoin treatment in female patients, resulting in Rash side effect. The patient was hospitalized.
Nitrofur Side Effect Report#9839016
Neuropathy Peripheral, Burning Sensation, Paraesthesia, Pain, Local Swelling, Rash Erythematous, Hypoaesthesia, Toxicity To Various Agents
This report suggests a potential Nitrofurantoin Neuropathy Peripheral side effect(s) that can have serious consequences. A 76-year-old female patient (weight: NA) from GB was diagnosed with the following symptoms/conditions: prophylaxis urinary tract infection and used Nitrofurantoin (dosage: 50 Milligram Daily;) starting
Feb 05, 2013. After starting Nitrofurantoin the patient began experiencing various side effects, including: Neuropathy Peripheral, Burning Sensation, Paraesthesia, Pain, Local Swelling, Rash Erythematous, Hypoaesthesia, Toxicity To Various AgentsAdditional drugs used concurrently:
  • Loperamide
  • Lansoprazole
  • Aspirin
  • Digoxin
  • Codeine Phosphate
Although Nitrofurantoin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Neuropathy Peripheral, may still occur.
Nitrofur Side Effect Report#9837558
Liver Function Test Abnormal, Immunoglobulins Increased
This Liver Function Test Abnormal problem was reported by a physician from GB. A 70-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: prophylaxis. On 201210 this consumer started treatment with Nitrofurantoin (dosage: 50 Milligram Daily; Inidcation: Prophylaxis For Recurrent Utis). The following drugs were being taken at the same time:
  • Amitriptyline
  • Aspirin
  • Atorvastatin
  • Bisoprolol
  • Enalapril
  • Tolterodine
  • Amlodipine
When using Nitrofurantoin, the patient experienced the following unwanted symptoms/side effects: Liver Function Test Abnormal, Immunoglobulins IncreasedThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Liver Function Test Abnormal, may become evident only after a product is in use by the general population.
Nitrofur Side Effect Report#9816176
Lung Disorder, Nocturia, Urinary Incontinence, Thinking Abnormal, Skin Irritation, Constipation, Speech Disorder
This Lung Disorder side effect was reported by a health professional from US. A 85-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Nitrofurantoin (drug dosage: Unk, 2x/day), which was initiated on NS. Concurrently used drugs:
  • Detrol La (Unk)
  • Magnesium (Unk)
  • Calcium (Unk)
.After starting to take Nitrofurantoin the consumer reported adverse symptoms, such as: Lung Disorder, Nocturia, Urinary Incontinence, Thinking Abnormal, Skin Irritation, Constipation, Speech DisorderThese side effects may potentially be related to Nitrofurantoin.
Nitrofur Side Effect Report#9813657
Musculoskeletal Chest Pain, Hyperhidrosis, Hypoxia, Musculoskeletal Chest Pain, Lung Infiltration
This is a report of a 82-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: urinary tract infection, who was treated with Nitrofurantoin (dosage: 1 Capsule, start time: NS), combined with:
  • Acetaminophen (tylenol)
  • Amb Home Oxygen
  • Apidra Solostar
  • B Complex
  • Calcium Carboante (caltrate)
  • Carvedilol (coreg)
  • Cholecalciferol (vitamin D)
  • Cyanocobalamin, Vitamin B-12
and developed a serious reaction and side effect(s): Musculoskeletal Chest Pain, Hyperhidrosis, Hypoxia, Musculoskeletal Chest Pain, Lung Infiltration after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Nitrofurantoin treatment in female patients, resulting in Musculoskeletal Chest Pain side effect. The patient was hospitalized.
Nitrofur Side Effect Report#9808249
Circulatory Collapse, Angina Pectoris, Dizziness, Tremor, Feeling Abnormal, Gait Disturbance
This report suggests a potential Nitrofurantoin-ratiopharm 100 Mg Retardkapseln Circulatory Collapse side effect(s) that can have serious consequences. A 65-year-old female patient (weight: NA) from DE was diagnosed with the following symptoms/conditions: cystitis noninfective,parkinson^s disease and used Nitrofurantoin-ratiopharm 100 Mg Retardkapseln (dosage: 100 Milligram Daily;) starting 201311. After starting Nitrofurantoin-ratiopharm 100 Mg Retardkapseln the patient began experiencing various side effects, including: Circulatory Collapse, Angina Pectoris, Dizziness, Tremor, Feeling Abnormal, Gait DisturbanceAdditional drugs used concurrently:
  • Stalevo
  • Sifrol Ret
  • Azilect
Although Nitrofurantoin-ratiopharm 100 Mg Retardkapseln demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Circulatory Collapse, may still occur.
Nitrofur Side Effect Report#9805281
Pulmonary Fibrosis
This Pulmonary Fibrosis problem was reported by a pharmacist from US. A 75-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: pulmonary fibrosis. On
Aug 20, 2013 this consumer started treatment with Nitrofurantoin (dosage: NA). The following drugs were being taken at the same time: NA. When using Nitrofurantoin, the patient experienced the following unwanted symptoms/side effects: Pulmonary FibrosisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Pulmonary Fibrosis, may become evident only after a product is in use by the general population.
Nitrofur Side Effect Report#9804117
Cheilitis, Skin Exfoliation, Nikolsky^s Sign
This Cheilitis side effect was reported by a health professional from FR. A 71-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Nitrofurantoin (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Pristinamycin
.After starting to take Nitrofurantoin the consumer reported adverse symptoms, such as: Cheilitis, Skin Exfoliation, Nikolsky^s SignThese side effects may potentially be related to Nitrofurantoin. The patient was hospitalized.
Nitrofur Side Effect Report#9803379
Neuropathy Peripheral, Dizziness, Clumsiness, Hypogeusia, Anosmia, Sensory Loss, Hypoaesthesia, Paraesthesia, Bradyphrenia
This is a report of a 34-year-old female patient (weight: NA) from GB, suffering from the following health symptoms/conditions: cystitis, who was treated with Nitrofurantoin (dosage: NA, start time:
Sep 13, 2013), combined with:
  • Sodium Citrate
  • Uva Ursi
  • Anadin Extra
  • Nurofen Express
  • Trimethoprim
and developed a serious reaction and side effect(s): Neuropathy Peripheral, Dizziness, Clumsiness, Hypogeusia, Anosmia, Sensory Loss, Hypoaesthesia, Paraesthesia, Bradyphrenia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Nitrofurantoin treatment in female patients, resulting in Neuropathy Peripheral side effect.
Nitrofur Side Effect Report#9788824
Paresis, Muscular Weakness
This report suggests a potential Nitrofurantoin-ratiopharm 100 Mg Retardkapseln Paresis side effect(s) that can have serious consequences. A 66-year-old female patient (weight: NA) from DE was diagnosed with the following symptoms/conditions: urinary tract infection and used Nitrofurantoin-ratiopharm 100 Mg Retardkapseln (dosage: 200 Milligram Daily;) starting
Feb 11, 2013. After starting Nitrofurantoin-ratiopharm 100 Mg Retardkapseln the patient began experiencing various side effects, including: Paresis, Muscular WeaknessAdditional drugs used concurrently: NA. Although Nitrofurantoin-ratiopharm 100 Mg Retardkapseln demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Paresis, may still occur.
Nitrofur Side Effect Report#9787921
Palpitations, Blood Pressure Systolic Increased, Renal Pain, Diarrhoea, Disorientation, Fatigue, Tremor, Balance Disorder, Dry Mouth
This Palpitations problem was reported by a consumer or non-health professional from US. A 89-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection. On
Dec 17, 2013 this consumer started treatment with Nitrofurantoin (dosage: Two Capsules Twice Daily Taken By Mouth). The following drugs were being taken at the same time: NA. When using Nitrofurantoin, the patient experienced the following unwanted symptoms/side effects: Palpitations, Blood Pressure Systolic Increased, Renal Pain, Diarrhoea, Disorientation, Fatigue, Tremor, Balance Disorder, Dry MouthAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Palpitations, may become evident only after a product is in use by the general population.
Nitrofur Side Effect Report#9781170
Myalgia, Fatigue, Chills, Tremor, Pyrexia, Dizziness, Rash
This Myalgia side effect was reported by a consumer or non-health professional from US. A 52-year-old female patient (weight:NA) experienced the following symptoms/conditions: cystitis.The patient was prescribed Nitrofurantoin (drug dosage: 1 Pill), which was initiated on
Dec 09, 2013. Concurrently used drugs: NA..After starting to take Nitrofurantoin the consumer reported adverse symptoms, such as: Myalgia, Fatigue, Chills, Tremor, Pyrexia, Dizziness, RashThese side effects may potentially be related to Nitrofurantoin.
Nitrofur Side Effect Report#9730516
Acute Hepatic Failure, Respiratory Failure, Cerebral Haemorrhage, Gastrointestinal Haemorrhage, Septic Shock, Clostridium Difficile Colitis, Coagulopathy, Pneumonia, Malnutrition
This is a report of a 50-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: urinary tract infection,pain, who was treated with Nitrofurantoin (dosage: NA, start time: NS), combined with:
  • Vicodin
  • Paracetamol
  • Hydromorphone Hydrochloride
  • Oral Contraceptive Nos (Estrogen Based)
and developed a serious reaction and side effect(s): Acute Hepatic Failure, Respiratory Failure, Cerebral Haemorrhage, Gastrointestinal Haemorrhage, Septic Shock, Clostridium Difficile Colitis, Coagulopathy, Pneumonia, Malnutrition after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Nitrofurantoin treatment in female patients, resulting in Acute Hepatic Failure side effect. The patient was hospitalized.
Nitrofur Side Effect Report#9729401
Hepatic Cirrhosis, Autoimmune Hepatitis, Jaundice, Chromaturia, Ascites, Oedema Peripheral
This report suggests a potential Nitrofurantoin Hepatic Cirrhosis side effect(s) that can have serious consequences. A 54-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: urinary tract infection and used Nitrofurantoin (dosage: NA) starting NS. After starting Nitrofurantoin the patient began experiencing various side effects, including: Hepatic Cirrhosis, Autoimmune Hepatitis, Jaundice, Chromaturia, Ascites, Oedema PeripheralAdditional drugs used concurrently: NA. Although Nitrofurantoin demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hepatic Cirrhosis, may still occur.
Nitrofur Side Effect Report#9728048
Headache, Nausea, Vomiting, Myalgia, Pyrexia, Night Sweats
This Headache problem was reported by a consumer or non-health professional from US. A 54-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: urinary tract infection. On
Nov 26, 2013 this consumer started treatment with Nitrofurantoin (dosage: NA). The following drugs were being taken at the same time: NA. When using Nitrofurantoin, the patient experienced the following unwanted symptoms/side effects: Headache, Nausea, Vomiting, Myalgia, Pyrexia, Night SweatsAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.
Nitrofur Side Effect Report#9728040
Miosis, Pharyngeal Oedema, Chest Discomfort
This Miosis side effect was reported by a consumer or non-health professional from US. A 78-year-old female patient (weight:NA) experienced the following symptoms/conditions: urinary tract infection.The patient was prescribed Nitrofurantoin (drug dosage: One Capsule, Twice Daily, Taken By Mouth), which was initiated on
Nov 30, 2013. Concurrently used drugs: NA..After starting to take Nitrofurantoin the consumer reported adverse symptoms, such as: Miosis, Pharyngeal Oedema, Chest DiscomfortThese side effects may potentially be related to Nitrofurantoin.
Nitrofur Side Effect Report#9708396
Atrial Fibrillation, Chest Discomfort, Heart Rate Irregular, Syncope, Dyspnoea
This is a report of a 55-year-old male patient (weight: NA) from DE, suffering from the following health symptoms/conditions: urogenital infection bacterial,prostatic specific antigen increased, who was treated with Nitrofurantoin-ratiopharm 100 Mg Retardkapseln (dosage: 200 Milligram Daily; 1-0-1, start time:
Oct 08, 2013), combined with: NA. and developed a serious reaction and side effect(s): Atrial Fibrillation, Chest Discomfort, Heart Rate Irregular, Syncope, Dyspnoea after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Nitrofurantoin-ratiopharm 100 Mg Retardkapseln treatment in male patients, resulting in Atrial Fibrillation side effect.


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The appearance of Nitrofur on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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What are common Nitrofur Side Effects for Women?

Women Side EffectsReports
Nausea 82
Chills 80
Dyspnoea 79
Headache 77
Pyrexia 67
Vomiting 55
Asthenia 51
Pain 48
Dizziness 47
Malaise 47

What are common Nitrofur Side Effects for Men?

Men Side EffectsReports
Dyspnoea 16
Asthenia 9
Pulmonary Fibrosis 9
Rash 9
Cough 8
Nausea 7
Pyrexia 7
Chills 6
Chromaturia 6
Abdominal Pain 5

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Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Nitrofur reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Discuss Nitrofur Side Effects

    Did You Have a Nitrofur Side Effect?

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    How Effective is Nitrofur for You?

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    Nitrofur Safety Alerts, Active Ingredients, Usage Information

    NDC0093-2130
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameNitrofurantoin Macrocrystals
    NameNitrofurantoin Macrocrystals
    Dosage FormCAPSULE
    RouteORAL
    On market since20070308
    LabelerTeva Pharmaceuticals USA Inc
    Active Ingredient(s)NITROFURANTOIN
    Strength(s)50
    Unit(s)mg/1
    Pharma ClassNitrofuran Antibacterial [EPC],Nitrofurans [Chemical/Ingredient]

    More About Nitrofur

    Side Effects reported to FDA: 726

    Nitrofur safety alerts: No

    Reported deaths: 31

    Reported hospitalizations: 230

    Latest Nitrofur clinical trials