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Insomnia (8)
Anxiety (6)
Chest Pain (5)
Tardive Dyskinesia Andakathisia (5)
Auditory Hallucinations (4)
Halucination (4)
Severe Headache (4)
>>View All User Submitted Nucynta Side Effects

Nucynta Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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  Showing 51-75 of 374 

Urinary Tract Infection, Choking (8242501-4)
on Mar 21, 2012 Female from CANADA , 37 years of age, was diagnosed with
  • fibromyalgia
and was treated with Nucynta Cr. Directly after, patient experienced the unwanted or unexpected Nucynta side effects: urinary tract infection, choking. Nucynta Cr dosage: 2 Times Per Day.

Pharyngeal Oedema, Speech Disorder, Swollen Tongue, Drooling, Dyspnoea, Dysphagia (8235229-8)
Patient was taking Nucynta. Patient felt the following Nucynta side effects: pharyngeal oedema, speech disorder, swollen tongue, drooling, dyspnoea, dysphagia on Mar 22, 2012 from UNITED STATES Additional patient health information: Male , weighting 250.0 lb, was diagnosed with
  • pain
  • contraception
  • nephrolithiasis
and. Nucynta dosage: 50 Mg Tablets Ndc 50458-0820-04.
Multiple prescriptions taken:
  • Alesse
  • Hydrochlorothiazide


Back Pain, Fungal Sepsis, Breakthrough Pain, Chest Discomfort, Immune System Disorder, Tremor (8231960-9)
Adverse event was reported on Mar 19, 2012 by a Male taking Nucynta (Dosage: 4 Times A Day) was diagnosed with
  • crohn's disease
  • depression
  • sleep disorder
  • headache
and. Location: UNITED STATES , weighting 110.0 lb, After Nucynta was administered, patient encountered several Nucynta side effects: back pain, fungal sepsis, breakthrough pain, chest discomfort, immune system disorder, tremor.
Multiple concurrent drugs taken:
  • Zoloft
  • Doxylamine Succinate
  • Topamax
  • Ambisome
Patient was hospitalized.

Dyspnoea, Hallucination, Dyskinesia, Abnormal Dreams (8230598-7)
on Mar 16, 2012 Female from UNITED STATES , 60 years of age, was diagnosed with
  • orthopedic procedure
and was treated with Nucynta Er. Directly after, patient experienced the unwanted or unexpected Nucynta side effects: dyspnoea, hallucination, dyskinesia, abnormal dreams. Nucynta Er dosage: N/A.


Blood Blister, Rash Macular, Pain In Extremity (8230597-5)
on Mar 16, 2012 Male from UNITED STATES , 74 years of age, weighting 190.0 lb, was diagnosed with
  • neuropathy peripheral
  • ill-defined disorder
and was treated with Nucynta. Patient felt the following Nucynta side effects: blood blister, rash macular, pain in extremity. Nucynta dosage: 1 Tablet Every 4 Hours.
Multiple prescriptions taken:
  • Coumadin


Mental Impairment, Activities Of Daily Living Impaired, Visual Impairment, Palpitations, Heart Rate Increased, Pruritus, Speech Disorder, Paranoia, Presyncope (8227205-6)
Patient was taking Nucynta. After Nucynta was administered, patient encountered several Nucynta side effects: mental impairment, activities of daily living impaired, visual impairment, palpitations, heart rate increased, pruritus, speech disorder, paranoia, presyncope on Mar 07, 2012 from UNITED STATES Additional patient health information: Female , weighting 145.0 lb, was diagnosed with
  • pain
and. Nucynta dosage: As Needed Up To 4 Times A Day.

Abdominal Discomfort, Blood Pressure Increased, Gastric Ulcer, Nausea (8227185-3)
Adverse event was reported on Mar 07, 2012 by a Female taking Nucynta (Dosage: 2 X 50 Mg Every 4-6 Hours) . Location: UNITED STATES , weighting 230.0 lb, Directly after, patient experienced the unwanted or unexpected Nucynta side effects: abdominal discomfort, blood pressure increased, gastric ulcer, nausea.

Hallucination, Visual, Breakthrough Pain, Hallucination, Auditory (8217753-7)
on Mar 12, 2012 Male from UNITED STATES , 29 years of age, was diagnosed with
  • back pain
and was treated with Nucynta. Patient felt the following Nucynta side effects: hallucination, visual, breakthrough pain, hallucination, auditory. Nucynta dosage: Four Times A Day Plus One A Day For Breakthrough Pain.

Abnormal Loss Of Weight (8214902-1)
on Mar 09, 2012 Female from UNITED STATES , weighting 197.0 lb, was diagnosed with
  • pain
and was treated with Nucynta Er. After Nucynta was administered, patient encountered several Nucynta side effects: abnormal loss of weight. Nucynta Er dosage: 1 To 2 Tablets Daily As Needed.

Withdrawal Syndrome, Lymphadenopathy, Platelet Count Increased, Panic Attack, Treatment Noncompliance (8214843-X)
Patient was taking Nucynta. Directly after, patient experienced the unwanted or unexpected Nucynta side effects: withdrawal syndrome, lymphadenopathy, platelet count increased, panic attack, treatment noncompliance on Mar 11, 2012 from UNITED STATES Additional patient health information: Female , 32 years of age, weighting 120.0 lb, . Nucynta dosage: 4 Times A Day.

Contusion, Depression, Sternal Fracture, Dizziness, Movement Disorder, Confusional State, Muscle Twitching, Dyspnoea (8212784-5)
Adverse event was reported on Mar 07, 2012 by a Female taking Nucynta (Dosage: N/A) . Location: UNITED STATES , 42 years of age, weighting 150.0 lb, Patient felt the following Nucynta side effects: contusion, depression, sternal fracture, dizziness, movement disorder, confusional state, muscle twitching, dyspnoea.

Paraesthesia, Blood Pressure Increased, Toxicity To Various Agents, Serotonin Syndrome (8212680-3)
on Mar 07, 2012 Female from UNITED STATES , 55 years of age, weighting 196.2 lb, was diagnosed with
  • pain
and was treated with Nucynta. After Nucynta was administered, patient encountered several Nucynta side effects: paraesthesia, blood pressure increased, toxicity to various agents, serotonin syndrome. Nucynta dosage: Every 4-6 Hours.
Multiple concurrent drugs taken:
  • Tobradex
  • Fluticasone
  • Clonidine
  • Paroxetine Hcl (Once Daily)
  • Ranitidine
  • Cytomel
Patient was hospitalized and became disabled.

Pain In Extremity, Blood Blister, Rash Macular (8212679-7)
on Mar 07, 2012 Male from UNITED STATES , 74 years of age, weighting 190.0 lb, was diagnosed with
  • neuropathy peripheral
  • ill-defined disorder
and was treated with Nucynta. Directly after, patient experienced the unwanted or unexpected Nucynta side effects: pain in extremity, blood blister, rash macular. Nucynta dosage: 1 Tablet Every 4 Hours.
Associated medications used:
  • Coumadin


Confusional State, Disorientation, Mental Disorder, Somnolence, Hallucination (8211742-4)
Patient was taking Nucynta. Patient felt the following Nucynta side effects: confusional state, disorientation, mental disorder, somnolence, hallucination on Mar 07, 2012 from UNITED STATES Additional patient health information: Male , 85 years of age, weighting 190.0 lb, was diagnosed with
  • pain
and. Nucynta dosage: N/A.
Multiple prescriptions taken:
  • Avinza (Am)
Patient was hospitalized.

Serotonin Syndrome, Withdrawal Syndrome (8211727-8)
Adverse event was reported on Mar 09, 2012 by a Male taking Nucynta Er (Dosage: Twice A Day) was diagnosed with
  • intervertebral disc protrusion
and. Location: UNITED STATES , weighting 190.0 lb, After Nucynta was administered, patient encountered several Nucynta side effects: serotonin syndrome, withdrawal syndrome.

Pharyngeal Oedema, Swollen Tongue (8205259-0)
on Mar 08, 2012 Female from UNITED STATES , weighting 160.0 lb, was diagnosed with
  • pain
  • nephrolithiasis
and was treated with Nucynta. Directly after, patient experienced the unwanted or unexpected Nucynta side effects: pharyngeal oedema, swollen tongue. Nucynta dosage: N/A.
Associated medications used:
  • Hydrochlorothiazide


Product Quality Issue, Palpitations, Heart Rate Increased, Speech Disorder, Paranoia, Hallucination, Pruritus, Visual Impairment, Mental Impairment (8193363-5)
on Mar 08, 2012 Female from UNITED STATES , weighting 145.0 lb, was diagnosed with
  • pain
and was treated with Nucynta. Patient felt the following Nucynta side effects: product quality issue, palpitations, heart rate increased, speech disorder, paranoia, hallucination, pruritus, visual impairment, mental impairment. Nucynta dosage: As Needed Up To 4 Times A Day.

Hallucination, Auditory, Nervousness, Insomnia, Loss Of Consciousness (8193362-3)
Patient was taking Nucynta. After Nucynta was administered, patient encountered several Nucynta side effects: hallucination, auditory, nervousness, insomnia, loss of consciousness on Feb 29, 2012 from UNITED STATES Additional patient health information: Female , weighting 134.0 lb, was diagnosed with
  • pain
and. Nucynta dosage: N/A.

Intentional Overdose, Confusional State, Pain (8179349-5)
Adverse event was reported on Feb 28, 2012 by a Male taking Nucynta (Dosage: N/A) . Location: UNITED STATES , 72 years of age, Directly after, patient experienced the unwanted or unexpected Nucynta side effects: intentional overdose, confusional state, pain. Patient was hospitalized.

Coma, Hallucination, Auditory, Nightmare (8178756-4)
on Mar 01, 2012 Male from UNITED STATES , 71 years of age, weighting 262.0 lb, was diagnosed with
  • pain
and was treated with Nucynta. Patient felt the following Nucynta side effects: coma, hallucination, auditory, nightmare. Nucynta dosage: ???. Patient was hospitalized.

Flatulence (8178453-5)
on Feb 27, 2012 Female from UNITED STATES , weighting 129.0 lb, was treated with Nucynta. After Nucynta was administered, patient encountered several Nucynta side effects: flatulence. Nucynta dosage: Unk.
Multiple concurrent drugs taken:
  • Vitamin D (Unk)
  • Hydrocodone (Unk)
  • Lantus (Unk)
  • Atenolol (Unk)
  • Metformin (Unk)
  • Lyrica (Unk)
  • Lovaza (Unk)


Psychotic Disorder (8177211-5)
Patient was taking Nucynta. Directly after, patient experienced the unwanted or unexpected Nucynta side effects: psychotic disorder on Feb 24, 2012 from UNITED STATES Additional patient health information: Male , 70 years of age, was diagnosed with
  • pain
and. Nucynta dosage: N/A.
Associated medications used:
  • Morphine Sulfate
  • Hydromorphone Hcl
  • Bupivacaine Hcl
  • Ms Contin
  • Morphine


Serotonin Syndrome, Withdrawal Syndrome (8169819-8)
Adverse event was reported on Feb 23, 2012 by a Male taking Nucynta Er (Dosage: Twice A Day) was diagnosed with
  • back pain
  • intervertebral disc protrusion
and. Location: UNITED STATES , weighting 190.0 lb, Patient felt the following Nucynta side effects: serotonin syndrome, withdrawal syndrome.
Multiple prescriptions taken:
  • Duragesic-100 (1 In 72hrs)
  • Duragesic-100 (1 In 72hrs)


Eye Disorder, Sedation, Depressed Level Of Consciousness (8169762-4)
on Feb 24, 2012 Female from UNITED STATES , 62 years of age, was diagnosed with
  • pain
  • depression
and was treated with Nucynta. After Nucynta was administered, patient encountered several Nucynta side effects: eye disorder, sedation, depressed level of consciousness. Nucynta dosage: N/A.
Multiple concurrent drugs taken:
  • Cymbalta (60 Mg Daily)


Presyncope, Hallucination, Mental Impairment, Visual Impairment, Paranoia, Activities Of Daily Living Impaired, Pruritus, Product Quality Issue, Dyspnoea (8163592-5)
on Feb 21, 2012 Female from UNITED STATES , weighting 145.0 lb, was diagnosed with
  • pain
and was treated with Nucynta. Directly after, patient experienced the unwanted or unexpected Nucynta side effects: presyncope, hallucination, mental impairment, visual impairment, paranoia, activities of daily living impaired, pruritus, product quality issue, dyspnoea. Nucynta dosage: As Needed Up To 4 Times A Day.

  Showing 51-75 of 374 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Nucynta Information

Alternative NUCYNTA Names:TAPENTADO

Active Ingredient: TAPENTADO

More About Nucynta

Side Effects reported to FDA: 374. View Nucynta Adverse Reports

Nucynta safety alerts: No

Reported deaths: 23

Reported hospitalizations: 103

Managing Your Medicines

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