Olanzapine Safety Questions, Olanzapine Answers
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Olanzapine Safety Reports
Total Olanzapine reports: 279.Olanzapine FDA safety alerts: 2002 2004 2005 .
Reported deaths: 66 Reported hospitalizations: 127.
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Reported Olanzapine Side Effects: weight increased, overdose, death, neuroleptic malignant syndrome, pulmonary embolism, somnolence, neutropenia, diabetes mellitus non-insulin-dependent, dyspnoea, diabetes mellitus insulin-dependent, deep vein thrombosis.
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Showing 1-50 of 279 Next >
Olanzapine Side Effects Report #5276587-6Consumer or non-health professional from DENMARK reported OLANZAPINE problem on Mar 20, 2007. Male patient, 71 years of age, was diagnosed with bipolar i disorder, restlessness, depression and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: fall, myoclonus, pneumonia. OLANZAPINE dosage: 5 MG, UNK. During the same period patient was treated with OXAPAX, CIPRALEX, LAMICTAL, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5276589-X
OLANZAPINE problem was reported by a Physician from THAILAND on Mar 19, 2007. Male patient, 40 years of age, was diagnosed with agitation and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, sepsis. OLANZAPINE dosage: unknown. During the same period patient was treated with BENZODIAZEPINE DERIVATIVES. Patient died on 12/22/2006.
Olanzapine Side Effects Report #5278227-9
Physician from JAPAN reported OLANZAPINE problem on Mar 16, 2007. Male patient, 38 years of age, weighting 165.3 lb, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: paroxysmal perceptual alteration. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with SEROQUEL. Patient recovered.
Olanzapine Side Effects Report #5278237-1
OLANZAPINE problem was reported by a Physician from DENMARK on Mar 22, 2007. Female patient, 66 years of age, was diagnosed with delusional disorder, persecutory type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: allergy to metals, erythema, face oedema, feeling hot, rash, swelling. OLANZAPINE dosage: 15-20 MG, DAILY (1/D). During the same period patient was treated with PERPHENAZINE, OXAZEPAM. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5284336-0
Physician from BELGIUM reported OLANZAPINE problem on Mar 22, 2007. Female patient, 15 years of age, was diagnosed with delusional disorder, persecutory type, diabetes mellitus insulin-dependent and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: agitation, delirium, hallucination, systemic lupus erythematosus. OLANZAPINE dosage: 5 MG, UNK. During the same period patient was treated with RISPERDAL, INSULIN. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5286558-1
OLANZAPINE problem was reported by a Physician from JAPAN on Mar 30, 2007. Male patient, 69 years of age, weighting 165.3 lb, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, tachycardia. OLANZAPINE dosage: 10 MG, 2/D. During the same period patient was treated with HALCION, VEGETAMIN A, VEGETAMIN B, SEPAZON, MAGMITT, MAGLAX, PRIMPERAN, GASMOTIN. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5290306-9
Physician from DENMARK reported OLANZAPINE problem on Apr 04, 2007. Female patient, weighting 8.82 lb, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: crying, feeding disorder neonatal, irritability, malaise, somnolence, weight decreased. OLANZAPINE dosage: unknown. During the same period patient was treated with ARIPIPRAZOLE, NORTRIPTYLINE, GRAVITAMON, VITAMIN D. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5290309-4
OLANZAPINE problem was reported by a Physician from GREECE on Apr 02, 2007. Female patient, 40 years of age, was diagnosed with psychotic disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: ascites, oedema, pericardial effusion, pleural effusion. OLANZAPINE dosage: 5 MG, DAILY (1/D). Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5290311-2
Physician from HUNGARY reported OLANZAPINE problem on Apr 02, 2007. Male patient, 25 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: delirium, extrapyramidal disorder, hyperhidrosis, hypotension, hypoxia, incontinence, leukocytosis, metabolic acidosis, neuroleptic malignant syndrome. OLANZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5298893-1
OLANZAPINE problem was reported by a Pharmacist from UNITED STATES on Apr 12, 2007. Male patient, 31 years of age, weighting 262.0 lb, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus. OLANZAPINE dosage: 30 MG QHS PO. During the same period patient was treated with HYDROXYZINE, ATORVASTATIN CALCIUM, DIVALPROEX. Patient recovered.
Olanzapine Side Effects Report #5299475-8
Physician from GREECE reported OLANZAPINE problem on Apr 11, 2007. Male patient, 24 years of age, weighting 235.9 lb, was diagnosed with depression and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, pulmonary embolism. OLANZAPINE dosage: 5 MG, DAILY (1/D). During the same period patient was treated with XANAX, CLARITHROMYCIN. Patient died on 02/21/2007.
Olanzapine Side Effects Report #5304096-4
OLANZAPINE problem was reported by a Physician from UNITED STATES on Apr 09, 2007. Male patient, 30 years of age, weighting 202.4 lb, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: decreased appetite, orthostatic hypotension. OLANZAPINE dosage: 10 MG, DAILY (1/D). Patient recovered.
Olanzapine Side Effects Report #5306887-2
Health Professional from UNITED STATES reported OLANZAPINE problem on Apr 11, 2007. Male patient, 34 years of age, was diagnosed with schizoaffective disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: anion gap increased, blood bicarbonate decreased, blood glucose increased, diabetes mellitus, diabetic ketoacidosis, glycosylated haemoglobin increased, urine ketone body present. OLANZAPINE dosage: 20 MG/D. During the same period patient was treated with LITHIUM CARBONATE, LAMOTRIGINE, CARBAMAZEPINE. Patient recovered.
Olanzapine Side Effects Report #5307452-3
OLANZAPINE problem was reported by a Physician from JAPAN on Apr 13, 2007. Male patient, 57 years of age, weighting 95.24 lb, was diagnosed with schizophrenia, residual type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: anaemia, blood thyroid stimulating hormone decreased, hypokalaemia, hypoproteinaemia, liver disorder. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with QUETIAPINE FUMARATE, PEROSPIRONE, FLUVOXAMINE MALEATE, PAROXETINE, CARBAMAZEPINE. Patient recovered.
Olanzapine Side Effects Report #5307453-5
Physician from FRANCE reported OLANZAPINE problem on Apr 12, 2007. Female patient, 36 years of age, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: anti-gad antibody positive, diabetes mellitus insulin-dependent, metabolic syndrome. OLANZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5311316-9
OLANZAPINE problem was reported by a Health Professional from UNITED STATES on Apr 17, 2007. Male patient, 43 years of age, was diagnosed with schizophrenia, paranoid type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: leukocytosis, monocyte count increased, neutrophil count increased, white blood cell count increased. OLANZAPINE dosage: 10 MG, QHS. During the same period patient was treated with PERPHENAZINE, VALPROATE, ATENOLOL, RANITIDINE, ACETYLSALICYLIC ACID SRT, CLOZAPINE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5314431-9
Physician from JAPAN reported OLANZAPINE problem on Apr 26, 2007. Male patient, 57 years of age, weighting 95.24 lb, was diagnosed with schizophrenia, residual type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: anaemia, blood thyroid stimulating hormone decreased, hypokalaemia, hypoproteinaemia, liver disorder. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with QUETIAPINE FUMARATE, PEROSPIRONE, FLUVOXAMINE MALEATE, PAROXETINE, CARBAMAZEPINE. Patient recovered.
Olanzapine Side Effects Report #5314434-4
OLANZAPINE problem was reported by a Physician from DENMARK on Apr 25, 2007. Female patient, weighting 8.82 lb, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: crying, feeding disorder neonatal, irritability, malaise, somnolence, weight decreased. OLANZAPINE dosage: unknown. During the same period patient was treated with ARIPIPRAZOLE, NORTRIPTYLINE, GRAVITAMON, VITAMIN D. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5314437-X
Physician from UNITED STATES reported OLANZAPINE problem on Apr 20, 2007. Male patient, 44 years of age, was diagnosed with schizoaffective disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, renal impairment. OLANZAPINE dosage: unknown. During the same period patient was treated with PAROXETINE, VALPROIC ACID, NAVANE. Patient recovered.
Olanzapine Side Effects Report #5315578-3
OLANZAPINE problem was reported by a Physician from JAPAN on Apr 25, 2007. Female patient, 22 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: blood pressure decreased, depressed level of consciousness, heart rate increased, lung disorder, somnolence. OLANZAPINE dosage: 50 MG, DAILY (1/D). During the same period patient was treated with VALPROATE, LORAZEPAM, AMOXAPINE, ETHYL LOFLAZEPATE, ETIZOLAM, ANAFRANIL. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5318195-4
Physician from ROMANIA reported OLANZAPINE problem on Apr 24, 2007. Female patient, 21 years of age, weighting 127.9 lb, was diagnosed with bipolar disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: bipolar disorder. OLANZAPINE dosage: 10 MG, UNK. During the same period patient was treated with VALPROATE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5318198-X
OLANZAPINE problem was reported by a Physician from ROMANIA on Apr 24, 2007. Male patient, 50 years of age, was diagnosed with bipolar disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: bipolar disorder. OLANZAPINE dosage: 10 MG, UNK. During the same period patient was treated with VALPROATE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5321823-0
Consumer or non-health professional from DENMARK reported OLANZAPINE problem on Apr 30, 2007. Male patient, 71 years of age, was diagnosed with bipolar i disorder, restlessness, depression and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: fall, myoclonus, pneumonia. OLANZAPINE dosage: 5 MG, UNK. During the same period patient was treated with OXAPAX, CIPRALEX, LAMICTAL, AMITRIPTYLINE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5323747-1
OLANZAPINE problem was reported by a Physician from ECUADOR on Apr 30, 2007. Male patient, 26 years of age, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: inguinal hernia, priapism. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with MIDAZOLAM. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5323773-2
Physician from GREECE reported OLANZAPINE problem on May 09, 2007. Male patient, 24 years of age, weighting 235.9 lb, was diagnosed with depression and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, pulmonary embolism. OLANZAPINE dosage: 5 MG, DAILY (1/D). During the same period patient was treated with XANAX, CLARITHROMYCIN. Patient died on 02/21/2007.
Olanzapine Side Effects Report #5326056-X
OLANZAPINE problem was reported by a Physician from GREECE on May 11, 2007. Male patient, 24 years of age, weighting 235.9 lb, was diagnosed with depression, nasopharyngitis and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, nasopharyngitis, pulmonary embolism. OLANZAPINE dosage: 5 MG, DAILY (1/D). During the same period patient was treated with XANAX, CLARITHROMYCIN. Patient died on 02/21/2007.
Olanzapine Side Effects Report #5328749-7
Consumer or non-health professional from UNITED STATES reported OLANZAPINE problem on May 16, 2007. Male patient, 79 years of age, weighting 170.0 lb, was diagnosed with schizophrenia, paranoid type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: hepatic neoplasm malignant. OLANZAPINE dosage: 25 MG 1XDAY. Patient recovered.
Olanzapine Side Effects Report #5330043-5
OLANZAPINE problem was reported by a Physician from BRAZIL on May 09, 2007. Male patient, 32 years of age, was diagnosed with schizophrenia, paranoid type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: neutropenia, prescribed overdose. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with CLOZAPINE. Patient recovered.
Olanzapine Side Effects Report #5331266-1
Physician from JAPAN reported OLANZAPINE problem on May 16, 2007. Male patient, 32 years of age, was diagnosed with schizophrenia, temporal lobe epilepsy and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: blood glucose decreased, disuse syndrome, gastroenteritis staphylococcal, neuroleptic malignant syndrome, sepsis. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with LULLAN, RISPERDAL, CARBAMAZEPINE. Patient was hospitalized and became disabled. Patient recovered.
Olanzapine Side Effects Report #5336488-1
OLANZAPINE problem was reported by a Physician from UNITED STATES on May 22, 2007. Female patient, 41 years of age, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, diabetic ketoacidosis, heparin-induced thrombocytopenia. OLANZAPINE dosage: 10 MG, DAILY (1/D). Patient was hospitalized. Patient died.
Olanzapine Side Effects Report #5337983-1
Physician from SPAIN reported OLANZAPINE problem on May 17, 2007. Female patient, 58 years of age, was diagnosed with schizophrenia, paranoid type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, blood glucose increased, electrocardiogram qt prolonged, heart rate increased, leukocytosis, loss of consciousness, metabolic acidosis, overdose. OLANZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5340102-9
OLANZAPINE problem was reported by a Physician from GREECE on May 29, 2007. Male patient, 24 years of age, weighting 235.9 lb, was diagnosed with depression, nasopharyngitis and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, nasopharyngitis, pulmonary embolism. OLANZAPINE dosage: 5 MG, DAILY (1/D). During the same period patient was treated with XANAX, CLARITHROMYCIN. Patient died on 02/21/2007.
Olanzapine Side Effects Report #5340103-0
Physician from JAPAN reported OLANZAPINE problem on May 25, 2007. Male patient, 66 years of age, weighting 165.3 lb, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: deep vein thrombosis, hyperlipidaemia, tachycardia. OLANZAPINE dosage: 10 MG, 2/D. During the same period patient was treated with HALCION, VEGETAMIN A, VEGETAMIN B, SEPAZON, MAGMITT, MAGLAX, PRIMPERAN, GASMOTIN. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5355381-1
OLANZAPINE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 28, 2007. Male patient, 29 years of age, was diagnosed with obsessive-compulsive disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: weight increased. OLANZAPINE dosage: unknown. During the same period patient was treated with ZOLOFT, DEPAKOTE. Patient recovered.
Olanzapine Side Effects Report #5357972-0
Consumer or non-health professional from UNITED STATES reported OLANZAPINE problem on Jan 03, 2007. Female patient, 58 years of age, weighting 190.9 lb, was diagnosed with depression and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: blood cholesterol abnormal, blood triglycerides increased, chest pain, diabetes mellitus, hypertension, hypotension, metabolic disorder. OLANZAPINE dosage: 5 MG. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5343567-1
OLANZAPINE problem was reported by a Physician from AUSTRALIA on May 22, 2007. Female patient, 32 years of age, was diagnosed with psychotic disorder, schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: neutropenia, white blood cell count decreased. OLANZAPINE dosage: 20 MG, DAILY (1/D). During the same period patient was treated with CLOZAPINE. Patient recovered.
Olanzapine Side Effects Report #5343568-3
Physician from UNITED KINGDOM reported OLANZAPINE problem on May 21, 2007. Female patient was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: agitation neonatal, foetal distress syndrome, hypertonia neonatal, hypoglycaemia neonatal, inappropriate antidiuretic hormone secretion, posture abnormal, streptococcal sepsis. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with PAROXETINE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5343569-5
OLANZAPINE problem was reported by a Physician from AUSTRALIA on May 21, 2007. Female patient, weighting 7.43 lb, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: agitation neonatal, foetal distress syndrome, hypertonia neonatal, hypoglycaemia neonatal, inappropriate antidiuretic hormone secretion, posture abnormal, streptococcal sepsis. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with PAROXETINE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5343586-5
Physician from TAIWAN, PROVINCE OF CHINA reported OLANZAPINE problem on May 24, 2007. Male patient, 62 years of age, was diagnosed with schizophrenia and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: electrocardiogram qt corrected interval prolonged, shock. OLANZAPINE dosage: 10 MG, DAILY (1/D). During the same period patient was treated with ARTANE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5350740-5
OLANZAPINE problem was reported by a Physician from ROMANIA on June 01, 2007. Female patient, 21 years of age, weighting 127.9 lb, was diagnosed with bipolar disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: bipolar disorder. OLANZAPINE dosage: 10 MG, UNK. During the same period patient was treated with VALPROATE. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5352834-7
Physician from SPAIN reported OLANZAPINE problem on June 01, 2007. Male patient, 25 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: loss of consciousness, overdose. OLANZAPINE dosage: unknown. Patient died.
Olanzapine Side Effects Report #5352842-6
OLANZAPINE problem was reported by a Physician from SPAIN on June 01, 2007. Male patient, 63 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: overdose. OLANZAPINE dosage: unknown. Patient died.
Olanzapine Side Effects Report #5352843-8
Physician from SPAIN reported OLANZAPINE problem on June 01, 2007. Female patient, 58 years of age, was diagnosed with schizophrenia, paranoid type and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: aspartate aminotransferase increased, blood creatine phosphokinase increased, blood glucose increased, electrocardiogram qt prolonged, intentional overdose, leukocytosis, loss of consciousness, metabolic acidosis. OLANZAPINE dosage: unknown. Patient was hospitalized. Patient recovered.
Olanzapine Side Effects Report #5352845-1
OLANZAPINE problem was reported by a Physician from SPAIN on June 01, 2007. Male patient, 38 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: overdose. OLANZAPINE dosage: unknown. Patient died.
Olanzapine Side Effects Report #5360234-9
Physician from SPAIN reported OLANZAPINE problem on June 12, 2007. Female patient, 63 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: overdose. OLANZAPINE dosage: unknown. Patient died.
Olanzapine Side Effects Report #5360238-6
OLANZAPINE problem was reported by a Physician from SPAIN on June 12, 2007. Female patient, 38 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: overdose. OLANZAPINE dosage: unknown. Patient died.
Olanzapine Side Effects Report #5360240-4
Physician from GREECE reported OLANZAPINE problem on June 07, 2007. Female patient, 43 years of age, was diagnosed with psychotic disorder and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: galactorrhoea. OLANZAPINE dosage: 10 MG, DAILY (1/D). Patient recovered.
Olanzapine Side Effects Report #5360253-2
OLANZAPINE problem was reported by a Physician from UNITED KINGDOM on June 11, 2007. Female patient was diagnosed with depression and was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: grand mal convulsion, white blood cell count increased. OLANZAPINE dosage: 7.5 MG, UNK. Patient recovered.
Olanzapine Side Effects Report #5363330-5
Physician from SWEDEN reported OLANZAPINE problem on May 11, 2007. Female patient was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: supraventricular extrasystoles. OLANZAPINE dosage: 5 MG, DAILY (1/D). Patient recovered.
Olanzapine Side Effects Report #5365401-6
OLANZAPINE problem was reported by a Physician from AUSTRALIA on June 12, 2007. Male patient, 55 years of age, was treated with OLANZAPINE. After drug was administered, patient experienced the following problems/side effects: agranulocytosis, diabetes mellitus. OLANZAPINE dosage: unknown. Patient recovered.
Showing 1-50 of 279 Next >
Drug Information: Olanzapine
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601213.html
(oh lan' za peen)IMPORTANT WARNING:
| [Posted 05/02/2007] FDA notified healthcare professionals that the Agency proposed that makers of all antidepressant medications update the existing black box warning on the prescribing information for their products to include warnings about the increased risks of suicidal thinking and behavior in young adults ages 18 to 24 years old during the first one to two months of treatment. The proposed labeling changes also state that scientific data did not show this increased risk in adults older than 24 years of age and that adults 65 years of age and older taking antidepressants have a decreased risk of suicidality. The proposed updates apply to the entire category of antidepressants. Individuals currently taking prescribed antidepressant medications should not stop taking them and should notify their healthcare professional if they have concerns. Manufacturers of antidepressant medications will have 30 days to submit their revised product labeling and revised Medication Guides to FDA for review. See the FDA press release for the list of products affected by the proposed antidepressant product labeling changes. For more information visit the FDA website at: http://www.fda.gov/medwatch/safety/2007/safety07.htm#Antidepressant, http://www.fda.gov/bbs/topics/NEWS/2007/NEW01624.html and http://www.fda.gov/cder/drug/antidepressants/default.htm. |
IMPORTANT WARNING:
| Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as olanzapine have an increased chance of death during treatment. Older adults with dementia may also have a greater chance of having a stroke or mini-stroke during treatment. If you experience any of the following symptoms, call your doctor immediately: slow or difficult speech, sudden dizziness or faintness, or weakness or numbness of an arm or leg.Olanzapine is not approved by the Food and Drug Administration (FDA) for the treatment of behavior disorders in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking olanzapine. For more information visit the FDA website: http://www.fda.gov/cder |
Why is this medication prescribed?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Olanzapine is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). It is also used to treat bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Olanzapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.
How should this medicine be used?
Olanzapine comes as a tablet and an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. It is usually taken once a day with or without food. Take olanzapine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take olanzapine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Do not try to push the orally disintegrating tablet through the foil. Instead ,use dry hands to peel back the foil packaging. Immediately take out the tablet and place it in your mouth. The tablet will quickly dissolve and can be swallowed with or without liquid.
Your doctor may start you on a low dose of olanzapine and gradually increase your dose.
Olanzapine may help control your symptoms, but it will not cure your condition. It may take several weeks or longer before you feel the full benefit of olanzapine. Continue to take olanzapine even if you feel well. Do not stop taking olanzapine without talking to your doctor. Your doctor will probably want to decrease your dose gradually.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Before taking olanzapine,
- tell your doctor and pharmacist if you are allergic to olanzapine or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants; antihistamines; carbamazepine (Tegretol); dopamine agonists such as bromocriptine (Parlodel), cabergoline (Dostinex), levodopa (Dopar, Larodopa), pergolide (Permax), and ropinirole (Requip); fluoroquinolone antibiotics including ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the United States), levofloxacin (Levaquin), norfloxacin (Noroxin), ofloxacin (Floxin), others; fluvoxamine (Luvox); ipratropium (Atrovent); medications for anxiety, hypertension, irritable bowel disease, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems; omeprazole (Prilosec); rifampin (Rifadin); sedatives; sleeping pills; ticlopidine (Ticlid); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you use or have ever used street drugs or have overused prescription medications and if you have or have ever had a stroke, a mini-stroke, heart disease or a heart attack, an irregular heartbeat, seizures, breast cancer, any condition that makes it difficult for you to swallow, high or low blood pressure, liver or prostate disease, paralytic ileus (condition in which food cannot move through the intestine); or glaucoma (an eye condition), or if you or anyone in your family has or has ever had diabetes. Also tell your doctor if you have ever had to stop taking a medication for mental illness because of severe side effects.
- tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while taking olanzapine, call your doctor. Do not breast-feed if you are taking olanzapine.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking olanzapine.
- you should know that olanzapine may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
- you should know that alcohol can add to the drowsiness caused by this medication. Do not drink alcohol while taking olanzapine.
- tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication.
- you should know that you may experience hyperglycemia (increases in your blood sugar) while you are taking this medication, even if you do not already have diabetes. If you have schizophrenia, you are more likely to develop diabetes than people who do not have schizophrenia, and taking olanzapine or similar medications may increase this risk. Tell your doctor immediately if you have any of the following symptoms while you are taking olanzapine: extreme thirst, frequent urination, extreme hunger, blurred vision, or weakness. It is very important to call your doctor as soon as you have any of these symptoms, because high blood sugar can cause a serious condition called ketoacidosis. Ketoacidosis may become life-threatening if it is not treated at an early stage. Symptoms of ketoacidosis include: dry mouth, nausea and vomiting, shortness of breath, breath that smells fruity, and decreased consciousness.
- you should know that olanzapine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking olanzapine. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
- you should know that olanzapine may make it harder for your body to cool down when it gets very hot. Tell your doctor if you plan to do vigorous exercise or be exposed to extreme heat.
- if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that the orally disintegrating tablets contain phenylalanine.
What special dietary instructions should I follow?
Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.
Be sure to drink plenty of water every day while you are taking this medication.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Olanzapine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- drowsiness
- dizziness
- restlessness
- unusual behavior
- depression
- difficulty falling asleep or staying asleep
- weakness
- difficulty walking
- constipation
- weight gain
- dry mouth
- pain in arms, legs, back, or joints
Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section or the SPECIAL PRECAUTIONS section, call your doctor immediately:
- seizures
- changes in vision
- swelling of the arms, hands, feet, ankles, or lower legs
- unusual movements of your face or body that you cannot control
- fever
- very stiff muscles
- excess sweating
- fast or irregular heartbeat
- rash
- hives
- difficulty breathing or swallowing
Olanzapine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Always store the orally disintegrating tablets in their sealed package, and use them immediately after opening the package. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- drowsiness
- slurred speech
- agitation
- fast heartbeat
- sudden movements that you cannot control
- coma (loss of consciousness for a period of time)
What other information should I know?
Pending revision, the material in this section should be considered in light of more recently available information in the MedWatch notification at the beginning of this monograph.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to olanzapine.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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