Orthoclone Side Effects summary

Total Orthoclone reports: 25. View

Orthoclone FDA safety alerts: No.

Reported deaths: 11

Reported hospitalizations: 11.

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Recently reported Orthoclone Side Effects


Common Orthoclone Side Effects
Cardiogenic shock 24%
Encephalopathy 20%
Brain herniation 16%
Brain oedema 16%
Cardio-respiratory arrest 16%
Haemolysis 16%
Meningitis aseptic 16%
Renal failure acute 16%
Death 12%
Pyrexia 12%
Aspergillosis 8%
Convulsion 8%
Heart transplant rejection 8%
Immunosuppression 8%
Multi-organ failure 8%
Musculoskeletal disorder 8%
Pneumonia  What is  Pneumonia                                                                                                                                                                                               8%
Respiratory failure 8%
Systemic inflammatory response syndrome 8%
Ventricular tachycardia 8%
Agitation 4%
Anaphylactic reaction 4%
Ascites 4%
Bronchospasm 4%
Capillary leak syndrome 4%
Chills 4%
Cold agglutinins positive 4%
Cold type haemolytic anaemia 4%
Complications of transplanted heart 4%
Complications of transplanted kidney 4%
Confusional state 4%
Depression  What is  Depression                                                                                                                                                                                              4%
Diffuse large b-cell lymphoma 4%
Dyspnoea 4%
Epstein-barr virus infection 4%
Fluid overload 4%
Headache  What is  Headache                                                                                                                                                                                                4%
Ileus 4%
Infection  What is  Infection                                                                                                                                                                                               4%
Influenza like illness 4%
Infusion related reaction 4%
Intracranial pressure increased 4%
Kidney transplant rejection 4%
Klebsiella infection 4%
Lymphoproliferative disorder 4%
Microangiopathic haemolytic anaemia 4%
Nausea  What is  Nausea                                                                                                                                                                                                  4%
Pain in extremity 4%
Photophobia 4%
Pulmonary oedema 4%
Renal failure 4%
Renal impairment 4%
Tachycardia 4%
Toxoplasmosis 4%

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Orthoclone Side Effects reported on Patientsville.com

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Orthoclone Side Effects reported to FDA

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Orthoclone Side Effects Report #5228434-6
Physician from JAPAN reported Orthoclone side effect on Jan 26, 2007. Male patient, 56 years of age, was diagnosed with transplant rejection, prophylaxis against transplant rejection, liver transplant What is  liver transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cardio-respiratory arrest, cardiogenic shock, encephalopathy, haemolysis, renal failure acute, ventricular tachycardia. Orthoclone dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, POLARAMINE, IMMUNE GLOBULIN INTRAVENOUS, VOLTAREN, CHLORTHALIDONE, CHLORPHENIRAMINE MALEATE, TACROLIMUS. Patient was hospitalized. Patient died on 01/26/2007.



Orthoclone Side Effects Report #5236862-8
Orthoclone side effect was reported by a Physician from JAPAN on Feb 05, 2007. Male patient, 56 years of age, was diagnosed with transplant rejection, prophylaxis against transplant rejection, liver transplant What is  liver transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cardio-respiratory arrest, cardiogenic shock, encephalopathy, haemolysis, multi-organ failure, pneumonia What is  pneumonia, renal failure acute. Orthoclone dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, POLARAMINE, IMMUNE GLOBULIN INTRAVENOUS, VOLTAREN, CHLORTHALIDONE, CHLORPHENIRAMINE MALEATE, TACROLIMUS. Patient was hospitalized. Patient died on 01/26/2007.



Orthoclone Side Effects Report #5254343-2
Physician from GERMANY reported Orthoclone side effect on Feb 27, 2007. Male patient, 16 years of age, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: heart transplant rejection. Orthoclone dosage: unknown. Patient died.



Orthoclone Side Effects Report #5228434-6
Orthoclone side effect was reported by a Physician from JAPAN on Jan 26, 2007. Male patient, 56 years of age, was diagnosed with transplant rejection, prophylaxis against transplant rejection, liver transplant What is  liver transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cardio-respiratory arrest, cardiogenic shock, encephalopathy, haemolysis, renal failure acute, ventricular tachycardia. Orthoclone dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, POLARAMINE, IMMUNE GLOBULIN INTRAVENOUS, VOLTAREN, CHLORTHALIDONE, CHLORPHENIRAMINE MALEATE, TACROLIMUS. Patient was hospitalized. Patient died on 01/26/2007.




Orthoclone Side Effects Report #5236862-8
Physician from JAPAN reported Orthoclone side effect on Feb 05, 2007. Male patient, 56 years of age, was diagnosed with transplant rejection, prophylaxis against transplant rejection, liver transplant What is  liver transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cardio-respiratory arrest, cardiogenic shock, encephalopathy, haemolysis, multi-organ failure, pneumonia What is  pneumonia, renal failure acute. Orthoclone dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, POLARAMINE, IMMUNE GLOBULIN INTRAVENOUS, VOLTAREN, CHLORTHALIDONE, CHLORPHENIRAMINE MALEATE, TACROLIMUS. Patient was hospitalized. Patient died on 01/26/2007.



Orthoclone Side Effects Report #5352699-3
Orthoclone side effect was reported by a Physician from GERMANY on May 31, 2007. Female patient, weighting 114.6 lb, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: ascites, capillary leak syndrome, convulsion, ileus, nausea What is  nausea, respiratory failure, tachycardia. Orthoclone dosage: unknown. Patient was hospitalized. Patient recovered.



Orthoclone Side Effects Report #5169783-X
Physician from ITALY reported Orthoclone side effect on Dec 01, 2006. Male patient, weighting 114.6 lb, was treated with Orthoclone. After drug was administered, patient experienced the following side effects: lymphoproliferative disorder. Orthoclone dosage: unknown. During the same period patient was treated with ATGAM. Patient died on 01/01/2003.



Orthoclone Side Effects Report #5474469-8
Orthoclone side effect was reported by a Health Professional from UNITED KINGDOM on Sept 26, 2007. Male patient, 26 years of age, weighting 145.5 lb, was diagnosed with kidney transplant rejection, thrombosis prophylaxis, dyspepsia and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: anaphylactic reaction, bronchospasm, influenza like illness, kidney transplant rejection, microangiopathic haemolytic anaemia, pyrexia, renal impairment. Orthoclone dosage: 5 MG, UNK. During the same period patient was treated with METHYLPREDNISOLONE, NEORAL, AZATHIOPRINE, TACROLIMUS, ASPIRIN, DOMPERIDONE, LANSOPRAZOLE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.



Orthoclone Side Effects Report #5598141-9
Health Professional from UNITED STATES reported Orthoclone side effect on Jan 17, 2008. Female patient, 18 years of age, was diagnosed with kidney transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: pulmonary oedema. Orthoclone dosage: 5 MG BOLUS IV. Patient recovered.




Orthoclone Side Effects Report #5716218-1
Orthoclone side effect was reported by a Physician from UNITED STATES on Apr 15, 2008. Male patient, 33 years of age, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: cold agglutinins positive. Orthoclone dosage: unknown. During the same period patient was treated with CYCLOSPORINE, THYMOGLOBULIN. Patient recovered.



Orthoclone Side Effects Report #5746621-5
Physician from UNITED STATES reported Orthoclone side effect on May 14, 2008. Male patient, 33 years of age, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: cold type haemolytic anaemia. Orthoclone dosage: unknown. During the same period patient was treated with CYCLOSPORINE, THYMOGLOBULIN. Patient recovered.



Orthoclone Side Effects Report #6010699-4
Orthoclone side effect was reported by a Physician from BRAZIL on Dec 10, 2008. Female patient, weighting 39.24 lb, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: meningitis aseptic, musculoskeletal disorder, systemic inflammatory response syndrome. Orthoclone dosage: unknown. Patient recovered.



Orthoclone Side Effects Report #6013996-1
Physician from BRAZIL reported Orthoclone side effect on Dec 10, 2008. Female patient, weighting 39.24 lb, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: meningitis aseptic, musculoskeletal disorder, systemic inflammatory response syndrome. Orthoclone dosage: unknown. Patient recovered.



Orthoclone Side Effects Report #4634928-4
Orthoclone side effect was reported by a Physician from on Apr 07, 2005. Female patient, 49 years of age, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: aspergillosis, cardiogenic shock, immunosuppression. Orthoclone dosage: unknown. During the same period patient was treated with TACROLIMUS, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient died.




Orthoclone Side Effects Report #4653439-3
Physician from reported Orthoclone side effect on Apr 29, 2005. Male patient, 49 years of age, weighting 220.5 lb, was diagnosed with transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: aspergillosis, cardiogenic shock, immunosuppression. Orthoclone dosage: unknown. During the same period patient was treated with TACROLIMUS, MYCOPHENOLATE MOFETIL, PREDNISONE, CYCLOSPORINE. Patient was hospitalized. Patient died on 07/15/2002.



Orthoclone Side Effects Report #4658417-6
Orthoclone side effect was reported by a Physician from on May 05, 2005. Female patient, 48 years of age, was diagnosed with transplant rejection, renal transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: diffuse large b-cell lymphoma, epstein-barr virus infection, toxoplasmosis. Orthoclone dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, STEROIDS. Patient was hospitalized. Patient recovered.



Orthoclone Side Effects Report #4761930-4
Physician from UNITED STATES reported Orthoclone side effect on Aug 02, 2004. Female patient, 41 years of age, was diagnosed with kidney transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: agitation, confusional state, depression What is  depression, encephalopathy, klebsiella infection, meningitis aseptic, pyrexia. Orthoclone dosage: unknown. During the same period patient was treated with TYLENOL, NORVASC, CATAPRES, NEORAL, BENADRYL, MINOXIDIL, LOPRESSOR, LANTUS. Patient was hospitalized. Patient recovered.



Orthoclone Side Effects Report #4761931-6
Orthoclone side effect was reported by a Pharmacist from UNITED STATES on July 28, 2004. Male patient, child 3 years of age, weighting 26.24 lb, was diagnosed with transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: dyspnoea, fluid overload, infusion related reaction. Orthoclone dosage: 5 MG, 1 IN 1 TOTAL; 2.5 MG, 1 IN 1 TOTAL; 2.5 MG, 1 IN 1 TOTAL; 5 MG. During the same period patient was treated with ORTHOCLONE OKT, ORTHOCLONE OKT, ORTHOCLONE OKT, TYLENOL, METHYLPRED, BENADRYL. Patient recovered.



Orthoclone Side Effects Report #4761932-8
Health Professional from UNITED STATES reported Orthoclone side effect on Feb 01, 2005. Female patient, 48 years of age, weighting 193.8 lb, was diagnosed with heart transplant rejection and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: renal failure, respiratory failure. Orthoclone dosage: 5 MG, 1 IN 1 DAY, INTRAVENOUS. Patient recovered.




Orthoclone Side Effects Report #4761933-X
Orthoclone side effect was reported by a Pharmacist from UNITED STATES on May 26, 2005. Male patient, 47 years of age, was treated with Orthoclone. After drug was administered, patient experienced the following side effects: convulsion. Orthoclone dosage: unknown. Patient recovered.



Orthoclone Side Effects Report #4834155-1
Physician from UNITED STATES reported Orthoclone side effect on Nov 11, 2005. Female patient was diagnosed with heart transplant What is  heart transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: heart transplant rejection. Orthoclone dosage: DOSE=0.1-0.2 MG/KG/DAY WITH A MAXIMUM DOSE OF 5 MG/DAY FOR 7 DOSES. During the same period patient was treated with ACETAMINOPHEN, HYDROCORTISONE, DIPHENYHYDRAMINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient died.



Orthoclone Side Effects Report #4836299-7
Orthoclone side effect was reported by a Physician from UNITED STATES on Nov 11, 2005. Female patient was diagnosed with heart transplant What is  heart transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: complications of transplanted kidney. Orthoclone dosage: DOSE=0.1-0.2 MG/KG/DAY WITH A MAXIMUM DOSE OF 5 MG/DAY FOR 7 DOSES. During the same period patient was treated with ACETAMINOPHEN, HYDROCORTISONE, DIPHENYHYDRAMINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient recovered.



Orthoclone Side Effects Report #4836300-0
Physician from UNITED STATES reported Orthoclone side effect on Nov 11, 2005. Female patient was diagnosed with heart transplant What is  heart transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: infection What is  infection. Orthoclone dosage: DOSE=0.1-0.2 MG/KG/DAY WITH A MAXIMUM DOSE OF 5 MG/DAY FOR 7 DOSES. During the same period patient was treated with ACETAMINOPHEN, HYDROCORTISONE, DIPHENYHYDRAMINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient died.



Orthoclone Side Effects Report #4838107-7
Orthoclone side effect was reported by a Physician from UNITED STATES on Nov 11, 2005. Female patient was diagnosed with heart transplant What is  heart transplant and was treated with Orthoclone. After drug was administered, patient experienced the following side effects: complications of transplanted heart. Orthoclone dosage: DOSE=0.1-0.2 MG/KG/DAY WITH A MAXIMUM DOSE OF 5 MG/DAY FOR 7 DOSES. During the same period patient was treated with ACETAMINOPHEN, HYDROCORTISONE, DIPHENYHYDRAMINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient recovered.




Orthoclone Side Effects Report #4883145-1
Consumer or non-health professional from UNITED STATES reported Orthoclone side effect on Jan 17, 2006. Female patient, 41 years of age, was treated with Orthoclone. After drug was administered, patient experienced the following side effects: chills, headache What is  headache, intracranial pressure increased, meningitis aseptic, pain in extremity, photophobia, pyrexia. Orthoclone dosage: unknown. Patient recovered.





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