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Review Oxaliplatin Safety Reports submitted to FDA

Total Oxaliplatin reports: 164.
Oxaliplatin FDA safety alerts: No.
Reported deaths: 44    Reported hospitalizations: 119.
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FDA Reported Oxaliplatin Side Effects: diarrhoea, dehydration, nausea, vomiting, disease progression, pyrexia, fatigue, dyspnoea exertional, asthenia, haemoglobin decreased, hypotension.
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Oxaliplatin Side Effects Report #5778498-6
Pharmacist from UNITED STATES reported OXALIPLATIN problem on June 18, 2008. Male patient, 60 years of age, weighting 441.0 lb, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: erythema, pruritus. OXALIPLATIN dosage: 170 MG ONCE IV. Patient recovered.

Oxaliplatin Side Effects Report #5778741-3
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on June 18, 2008. Male patient, 70 years of age, weighting 163.0 lb, was diagnosed with oesophageal adenocarcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: disease progression, dysphasia, oesophageal adenocarcinoma. OXALIPLATIN dosage: 164 MG EVERY OTHER WEEK IV DRIP. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, FOLFOX. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5783163-5
Health Professional from UNITED STATES reported OXALIPLATIN problem on June 19, 2008. Female patient, weighting 158.0 lb, was diagnosed with laryngeal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: blood culture positive, laryngeal cancer, malignant neoplasm progression, nausea, pneumonia, staphylococcal infection, vomiting. OXALIPLATIN dosage: 145MG DAY 1+15 Q 28 DAYS IV. During the same period patient was treated with XELODA. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5786037-9
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on June 20, 2008. Male patient, 56 years of age, weighting 139.0 lb, was diagnosed with oesophageal adenocarcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, dehydration, disease progression, dysphasia, oedema, oedema peripheral, pulmonary oedema, secretion discharge. OXALIPLATIN dosage: 115MG EVERY OTHER WEEK IV DRIP. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient died on 06/03/2008.

Oxaliplatin Side Effects Report #5788512-X
Health Professional from UNITED STATES reported OXALIPLATIN problem on June 25, 2008. Female patient, 41 years of age, weighting 132.3 lb, was diagnosed with rectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: catheter site related reaction, erythema, incision site complication, infection, pain, purulence. OXALIPLATIN dosage: 400MG/M2 = 67MG WEEKLY IV. During the same period patient was treated with FLUOROURACIL, AVASTIN. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5789261-4
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on June 25, 2008. Male patient, 70 years of age, weighting 163.0 lb, was diagnosed with oesophageal adenocarcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, condition aggravated, disease progression. OXALIPLATIN dosage: 164MG EVERY OTHER WEEK IV DRIP. During the same period patient was treated with LEUCOVORIN IVP, FLUOROURACIL, IVCI, FOLFOX. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5793653-7
Physician from GERMANY reported OXALIPLATIN problem on June 25, 2008. Female patient was diagnosed with colorectal cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, blood amylase increased, blood bilirubin increased. OXALIPLATIN dosage: unknown. During the same period patient was treated with CAPECITABINE, AVASTIN. Patient was hospitalized. Patient died on 04/25/2008.

Oxaliplatin Side Effects Report #5730332-6
OXALIPLATIN problem was reported by a Health Professional from TURKEY on Apr 17, 2008. Male patient, 66 years of age, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: chronic myeloid leukaemia, metastases to liver. OXALIPLATIN dosage: 130 MG/M2, (DAY 1 OF 21), 5 CYCLES. During the same period patient was treated with IRINOTECAN, LEUCOVORIN CALCIUM, FLUOROURACIL, RALTITREXED, CAPECITABINE. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5730423-X
Pharmacist from UNITED STATES reported OXALIPLATIN problem on May 05, 2008. Female patient, 66 years of age, was diagnosed with colon cancer stage iii and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: neuropathy peripheral. OXALIPLATIN dosage: 85 MG/M2 Q2WEEKS IV DRIP. Patient recovered.

Oxaliplatin Side Effects Report #5737611-7
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on May 12, 2008. Male patient, 52 years of age, weighting 179.9 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: clostridium difficile colitis, dehydration, nausea. OXALIPLATIN dosage: 85MG/M2 DAY 1+15/Q 28 D IV. During the same period patient was treated with DOCETAXEL, WARFARIN, LEXAPRO, OXYCONTIN, DECADRON. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5738687-3
Health Professional from UNITED STATES reported OXALIPLATIN problem on May 14, 2008. Male patient, 52 years of age, weighting 179.9 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: clostridium difficile colitis, dehydration, disease progression, lung cancer metastatic, nausea, vomiting. OXALIPLATIN dosage: 85MG/M2 DAY 1 AND 15 / Q 28 IV. During the same period patient was treated with DOCETAXEL, WARFARIN, LEXAPRO, OXYCONTIN, DECADRON. Patient was hospitalized. Patient died on 04/02/2008.

Oxaliplatin Side Effects Report #5743007-4
OXALIPLATIN problem was reported by a Physician from SPAIN on May 15, 2008. Male patient, weighting 172.0 lb, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: acute myocardial infarction. OXALIPLATIN dosage: unknown. During the same period patient was treated with XELODA. Patient died on 05/06/2008.

Oxaliplatin Side Effects Report #5744001-X
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on May 16, 2008. Male patient, 78 years of age, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: mucous membrane disorder, rectal haemorrhage, thrombocytopenia. OXALIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5746863-9
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on May 19, 2008. Male patient, weighting 233.9 lb, was diagnosed with colorectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, haematoma. OXALIPLATIN dosage: unknown. During the same period patient was treated with ATIVAN, METOPROLOL TARTRATE, VICODIN, CYMBALTA, LYRICA, FLUOROURACIL. Patient was hospitalized. Patient died on 05/07/2008.

Oxaliplatin Side Effects Report #5691428-0
Health Professional from UNITED STATES reported OXALIPLATIN problem on Apr 01, 2008. Male patient, 60 years of age, weighting 144.0 lb, was diagnosed with rectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: asthenia, disease progression, myoclonus, nuclear magnetic resonance imaging brain abnormal, unresponsive to stimuli. OXALIPLATIN dosage: unknown. During the same period patient was treated with BEVACIZUMAB, CETUXIMAB, XELODA, PEPCID, HYDROCHLOROTHIAZIDE, PHENYTOIN, DECADRON, MAG OXIDE. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5693051-0
OXALIPLATIN problem was reported by a Pharmacist from UNITED STATES on Apr 02, 2008. Male patient, 46 years of age, weighting 240.0 lb, was diagnosed with neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: flushing, hypotension, syncope. OXALIPLATIN dosage: 200MG IV DRIP. During the same period patient was treated with AVASTIN, ZOFRAN, DECADRON, CALCIUM, MAGNESIUM. Patient recovered.

Oxaliplatin Side Effects Report #5693154-0
Pharmacist from UNITED STATES reported OXALIPLATIN problem on Apr 02, 2008. Male patient, 43 years of age, weighting 221.0 lb, was diagnosed with neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: feeling hot, flushing, hypotension, infusion related reaction. OXALIPLATIN dosage: 200MG IV DRIP. During the same period patient was treated with AVASTIN, ALOXI, DECADRON, ATIVAN. Patient recovered.

Oxaliplatin Side Effects Report #5696229-5
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Apr 01, 2008. Male patient, weighting 188.5 lb, was diagnosed with neoplasm malignant, hyperkalaemia, pneumonia, clostridial infection, neutropenia and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: arrhythmia, aspiration, dehydration, hyperkalaemia, metabolic acidosis, vomiting. OXALIPLATIN dosage: unknown. During the same period patient was treated with DOCETAXEL, KAYEXALATE, BICARBONATE, ALBUTEROL, METRONIDAZOLE, FILGRASTIM. Patient was hospitalized. Patient died on 10/17/2007.

Oxaliplatin Side Effects Report #5696254-4
Physician from NETHERLANDS reported OXALIPLATIN problem on Mar 28, 2008. Female patient was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea. OXALIPLATIN dosage: unknown. During the same period patient was treated with XELODA. Patient was hospitalized. Patient died.

Oxaliplatin Side Effects Report #5698368-1
OXALIPLATIN problem was reported by a Consumer or non-health professional from ITALY on Mar 25, 2008. Female patient, 76 years of age, was diagnosed with rectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, biopsy salivary gland abnormal, carcinoembryonic antigen increased, gastrointestinal neoplasm, malignant neoplasm progression, metastases to lung, metastatic neoplasm, mucosal inflammation. OXALIPLATIN dosage: 100 MG/M2 STOPPED (ON DAY 1 FOR 2 14-DAYS-CYCLES). During the same period patient was treated with FOLINIC ACID, FLUOROURACIL, RALTITREXID. Patient was hospitalized. Patient died.

Oxaliplatin Side Effects Report #5704527-1
Pharmacist from UNITED STATES reported OXALIPLATIN problem on Apr 11, 2008. Male patient, 42 years of age, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest, convulsion, depressed level of consciousness. OXALIPLATIN dosage: unknown. Patient recovered.

Oxaliplatin Side Effects Report #5705835-0
OXALIPLATIN problem was reported by a Pharmacist from NETHERLANDS on Apr 02, 2008. Male patient, 62 years of age, weighting 198.4 lb, was diagnosed with colon cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, hypersensitivity. OXALIPLATIN dosage: 260 MG/500 ML (40-50 ML GIVEN). During the same period patient was treated with XELODA. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5705836-2
Health Professional from NETHERLANDS reported OXALIPLATIN problem on Apr 02, 2008. Male patient, 73 years of age, was diagnosed with colorectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: myocardial infarction. OXALIPLATIN dosage: unknown. During the same period patient was treated with AVASTIN, XELODA. Patient recovered.

Oxaliplatin Side Effects Report #5706195-1
OXALIPLATIN problem was reported by a Physician from CHINA on Apr 04, 2008. Male patient, 49 years of age, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: tinnitus. OXALIPLATIN dosage: unknown. During the same period patient was treated with XELODA. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5715592-X
Health Professional from UNITED STATES reported OXALIPLATIN problem on Apr 23, 2008. Male patient, 52 years of age, weighting 179.9 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: dehydration, nausea. OXALIPLATIN dosage: 85MG/M2 DAY 1+15/Q28D IV. During the same period patient was treated with DOCETAXEL, WARFARIN, LEXAPRO, OXYCONTIN, DECADRON. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5719318-5
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Apr 25, 2008. Male patient, 52 years of age, weighting 179.9 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: clostridium difficile colitis, dehydration, nausea, vomiting. OXALIPLATIN dosage: 85MG/M2 DAY 1+15/Q28ML IV. During the same period patient was treated with DOCETAXEL, WARFARIN, LEXAPRO, OXYCONTIN, DECADRON. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5345999-4
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on June 04, 2007. Male patient, 77 years of age, weighting 235.9 lb, was diagnosed with colorectal cancer metastatic, vitamin supplementation, dyspepsia, gout, depression and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea. OXALIPLATIN dosage: unknown. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, PRILOSEC, ALLOPURINOL, PREDNISONE, FLUOXETINE. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5346194-5
OXALIPLATIN problem was reported by a Health Professional from KOREA, REPUBLIC OF on May 30, 2007. Female patient, weighting 138.0 lb, was diagnosed with hepatic neoplasm malignant, hypothyroidism and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: pancytopenia. OXALIPLATIN dosage: unknown. During the same period patient was treated with DOXORUBICIN, SYNTHROID. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5350899-X
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on June 06, 2007. Female patient, weighting 119.0 lb, was diagnosed with pancreatic carcinoma metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: blood calcium decreased, blood chloride decreased, blood magnesium decreased, blood sodium decreased, electrocardiogram st-t change, hyperglycaemia, hypertension, transient ischaemic attack. OXALIPLATIN dosage: 130 MG/M2 DAY 1 OF 3 WEEKC INFUSION. During the same period patient was treated with DEXAMETHASONE, COMPAZINE, ATIVAN, PERCOCET, ZOFRAN. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5355775-4
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on June 11, 2007. Male patient, weighting 145.5 lb, was diagnosed with prostate cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cerebral atrophy, confusional state, mental status changes. OXALIPLATIN dosage: 94 MG/M^2 Q 21 DAYS IV. During the same period patient was treated with PEMETREXED, METFORMIN. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5355964-9
Health Professional from reported OXALIPLATIN problem on June 08, 2007. Female patient, 65 years of age, weighting 177.9 lb, was diagnosed with carcinoid tumour of the appendix and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: acidosis, bone marrow failure, haemoglobin decreased, leukopenia, lymphopenia, neutrophil count decreased, platelet count decreased, staphylococcal bacteraemia. OXALIPLATIN dosage: unknown. During the same period patient was treated with PREMPRO, LIPITOR. Patient died on 06/07/2007.

Oxaliplatin Side Effects Report #5357706-X
OXALIPLATIN problem was reported by a Health Professional from UNITED KINGDOM on June 05, 2007. Male patient, 55 years of age, weighting 143.3 lb, was diagnosed with colorectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: eye pain, laryngospasm, paraesthesia. OXALIPLATIN dosage: unknown. Patient recovered.

Oxaliplatin Side Effects Report #5358481-5
Physician from UNITED STATES reported OXALIPLATIN problem on June 14, 2007. Female patient, 71 years of age, weighting 152.1 lb, was diagnosed with adenocarcinoma, metastasis and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cerebrovascular accident, dysarthria, hemiparesis. OXALIPLATIN dosage: 175 MG EVERY 2 WEEKS IV DRIP. During the same period patient was treated with GEMCITABINE. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5358527-4
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on June 14, 2007. Male patient, 48 years of age, weighting 154.0 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: back pain, dyspnoea, flushing. OXALIPLATIN dosage: 149 MG EVERY 2 WEEKS IV. Patient recovered.

Oxaliplatin Side Effects Report #5362057-3
Health Professional from UNITED STATES reported OXALIPLATIN problem on June 15, 2007. Female patient, 65 years of age, weighting 178.0 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: anaemia postoperative, bacteraemia, metabolic acidosis, multi-organ failure, procedural hypotension, pyrexia, respiratory failure, tachycardia. OXALIPLATIN dosage: 482MG INTRAPERITONEAL. During the same period patient was treated with LIPITOR, PREMPRO. Patient died on 06/07/2007.

Oxaliplatin Side Effects Report #5314508-8
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on May 01, 2007. Male patient, 60 years of age, weighting 171.0 lb, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, blood potassium decreased, dehydration, diarrhoea, frequent bowel movements, nausea, pyrexia, vomiting. OXALIPLATIN dosage: 100 MG D 1 AND D 8 IV DRIP. During the same period patient was treated with XELODA. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5316089-1
Physician from UNITED STATES reported OXALIPLATIN problem on Apr 30, 2007. Male patient, weighting 159.0 lb, was diagnosed with colon cancer recurrent and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal distension, asthenia, cardiac arrest, diarrhoea, hepatitis, intestinal ischaemia, intestinal perforation, mucosal inflammation, myalgia. OXALIPLATIN dosage: unknown. During the same period patient was treated with XELODA, AVASTIN, ZOCOR. Patient was hospitalized. Patient died on 01/02/2007.

Oxaliplatin Side Effects Report #5316741-8
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on May 01, 2007. Male patient, 60 years of age, weighting 171.0 lb, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, dehydration, diarrhoea, nausea, pyrexia, vomiting. OXALIPLATIN dosage: 100 MG D1 + D8 IV DRIP. During the same period patient was treated with XELODA. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5323949-4
Health Professional from UNITED STATES reported OXALIPLATIN problem on May 09, 2007. Male patient, weighting 136.7 lb, was diagnosed with metastases to bone, metastases to liver, rectal cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: impaired healing, incision site complication, seroma, wound infection. OXALIPLATIN dosage: 85MG/M2 D1 AND D15 IV. During the same period patient was treated with AVASTIN, XELODA. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5327276-0
OXALIPLATIN problem was reported by a Health Professional from GERMANY on May 15, 2007. Male patient, 68 years of age, was diagnosed with colorectal cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, neutropenia, thrombocytopenia. OXALIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID. Patient died on 11/08/2006.

Oxaliplatin Side Effects Report #5328763-1
Health Professional from UNITED STATES reported OXALIPLATIN problem on May 16, 2007. Male patient, 60 years of age, weighting 158.0 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: flushing, infusion related reaction, pruritus. OXALIPLATIN dosage: unknown. Patient recovered.

Oxaliplatin Side Effects Report #5333106-3
OXALIPLATIN problem was reported by a Pharmacist from UNITED STATES on May 21, 2007. Male patient, 74 years of age, weighting 130.0 lb, was diagnosed with gastric cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: clostridial infection, diarrhoea, hypotension, neutropenia. OXALIPLATIN dosage: unknown. During the same period patient was treated with DOCETAXEL, FLUOROURACIL. Patient was hospitalized. Patient died on 02/15/2007.

Oxaliplatin Side Effects Report #5333186-5
Physician from GERMANY reported OXALIPLATIN problem on May 16, 2007. Male patient, weighting 185.2 lb, was diagnosed with colon cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: bradycardia, syncope. OXALIPLATIN dosage: unknown. Patient recovered.

Oxaliplatin Side Effects Report #5333504-8
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on May 22, 2007. Male patient, weighting 177.0 lb, was diagnosed with oesophageal adenocarcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: chills, decreased appetite, haemodynamic instability, hypernatraemia, hypotension, hypoxia, neutropenia, pulmonary embolism, pyrexia. OXALIPLATIN dosage: 50 MG/M2 1/WK --M-F 28 DY IV. During the same period patient was treated with CAPECITABINE, CETUXIMAB, CORTISONE ACETATE, ORAL POTASSIUM SUPPLEMENTS, LASIX, PREVACID. Patient died on 05/20/2007.

Oxaliplatin Side Effects Report #5334401-4
Health Professional from UNITED STATES reported OXALIPLATIN problem on May 23, 2007. Male patient, weighting 175.0 lb, was diagnosed with oesophageal adenocarcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: haemoptysis, hyperglycaemia, lymphoedema, visual acuity reduced. OXALIPLATIN dosage: 50 MG/M2 1/2K --M-F 28 DY IV. During the same period patient was treated with CAPECITABINE, CETUXIMAB, BENZONATATE, MUCINEX, RANITIDINE, PRILOSEC. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5336696-X
OXALIPLATIN problem was reported by a Pharmacist from UNITED STATES on May 24, 2007. Male patient, 46 years of age, weighting 164.0 lb, was diagnosed with pancreatic carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: dysaesthesia pharynx, glossodynia, infusion related reaction, speech disorder, tongue disorder. OXALIPLATIN dosage: unknown. During the same period patient was treated with AVASTIN, ASPIRIN, CAPTOPRIL, COREG, LASIX, GLIPZIDE, TUSSIONEX, ZOLOFT. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5293582-1
Health Professional from KOREA, REPUBLIC OF reported OXALIPLATIN problem on Apr 06, 2007. Female patient, weighting 138.0 lb, was diagnosed with hepatic neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: pancytopenia. OXALIPLATIN dosage: unknown. During the same period patient was treated with DOXORUBICIN. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5299327-3
OXALIPLATIN problem was reported by a Pharmacist from UNITED STATES on Apr 11, 2007. Male patient, 57 years of age, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: hypoaesthesia, neuropathy, paraesthesia. OXALIPLATIN dosage: unknown. Patient recovered.

Oxaliplatin Side Effects Report #5302634-9
Health Professional from UNITED KINGDOM reported OXALIPLATIN problem on Apr 11, 2007. Male patient, 55 years of age, weighting 143.3 lb, was diagnosed with colorectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: laryngospasm, paraesthesia. OXALIPLATIN dosage: unknown. Patient recovered.

Oxaliplatin Side Effects Report #5306830-6
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Apr 20, 2007. Male patient, weighting 277.0 lb, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: pallor, stridor, throat tightness. OXALIPLATIN dosage: 325MG IV. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5254325-0
Physician from JAPAN reported OXALIPLATIN problem on Feb 20, 2007. Male patient, weighting 149.9 lb, was diagnosed with rectal cancer, nausea, vomiting and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cardiac failure, cardiomegaly, disease progression, dyspnoea exertional, lymphangiosis carcinomatosa, metastases to lung. OXALIPLATIN dosage: unknown. During the same period patient was treated with DECADRON, KYTRIL, FLUOROURACIL, LEUCOVORIN CALCIUM. Patient died on 10/02/2006.

Oxaliplatin Side Effects Report #5256926-2
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Mar 05, 2007. Female patient, weighting 160.0 lb, was diagnosed with metastatic carcinoma of the bladder and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea, haemoglobin decreased, hypokalaemia, hypomagnesaemia, ill-defined disorder, liver function test abnormal, metastases to liver, nausea, urinary tract infection. OXALIPLATIN dosage: 110MG/M2 Q 21 DAYS IV DRIP. During the same period patient was treated with DOCETAXOL. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5259022-3
Physician from UNITED STATES reported OXALIPLATIN problem on Feb 20, 2007. Female patient, 60 years of age, weighting 196.0 lb, was diagnosed with colon cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: coronary artery occlusion, fall, metabolic disorder, myocardial infarction, stress. OXALIPLATIN dosage: 157MG IV. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, VALSARTAN, EZETIMIBE, NIACIN, ASPIRIN, MELOXICAM. Patient died on 02/16/2007.

Oxaliplatin Side Effects Report #5259029-6
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Feb 20, 2007. Female patient, 60 years of age, was diagnosed with colon cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: coronary artery occlusion, metabolic disorder, myocardial infarction, pulmonary embolism, stress. OXALIPLATIN dosage: 157MG IV. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, VALSARTAN, EZETIMIBE, NIACIN, ASPIRIN, MELOXICAM. Patient died on 02/16/2007.

Oxaliplatin Side Effects Report #5266047-0
Health Professional from UNITED STATES reported OXALIPLATIN problem on Mar 13, 2007. Male patient, weighting 170.6 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: asthenia, brain oedema, headache, mental status changes. OXALIPLATIN dosage: 85MG/M2 DAY 1+15 Q28 IV. During the same period patient was treated with DOCETAXEL DAYS. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5266048-2
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Mar 13, 2007. Male patient, 59 years of age, weighting 170.6 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: bacterial infection, blood culture positive, mental status changes, staphylococcal infection, white blood cell count increased. OXALIPLATIN dosage: 85MG/M2 DAYS 1+15/Q28 IV. During the same period patient was treated with DOCETAXEL. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5268324-6
Physician from UNITED STATES reported OXALIPLATIN problem on Mar 15, 2007. Male patient, weighting 159.2 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: pancytopenia. OXALIPLATIN dosage: 85 MG/M2 IV = 160MG Q2WEEKS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient recovered.

Oxaliplatin Side Effects Report #5268834-1
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Feb 20, 2007. Female patient, 60 years of age, weighting 196.0 lb, was diagnosed with colon cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: coronary artery disease, coronary artery occlusion, myocardial infarction, pulmonary embolism. OXALIPLATIN dosage: 157MG IV. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, VALSARTAN, EZETIMIBE, NIACIN, ASPIRIN, MELOXICAM. Patient died on 02/16/2007.

Oxaliplatin Side Effects Report #5270285-0
Health Professional from UNITED KINGDOM reported OXALIPLATIN problem on Mar 13, 2007. Female patient, 57 years of age, weighting 121.3 lb, was diagnosed with colorectal cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cerebral infarction, eye pain, headache, vision blurred. OXALIPLATIN dosage: 144 MG. During the same period patient was treated with FLUOROURACIL. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5271556-4
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Dec 13, 2006. Male patient, 68 years of age, weighting 161.0 lb, was diagnosed with colon cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, blood alkaline phosphatase increased, blood glucose increased, blood magnesium decreased, coronary arterial stent insertion, electrocardiogram st segment depression, nausea, vomiting. OXALIPLATIN dosage: 160MG IVPB Q2W. During the same period patient was treated with ASPIRIN, COZAAR, ZEBETA, LIPITOR, ALOXI, DECADRON, PLAVIX. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5272113-6
Health Professional from UNITED STATES reported OXALIPLATIN problem on Feb 20, 2007. Female patient, 60 years of age, was diagnosed with colorectal cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: myocardial infarction, pulmonary embolism. OXALIPLATIN dosage: 157 MILLIGRAM IV. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, VALSARTAN, EZETIMIBE, MELOXICAM, FLONASE, ASPIRIN. Patient died.

Oxaliplatin Side Effects Report #5279123-3
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Mar 27, 2007. Female patient, weighting 152.0 lb, was diagnosed with bladder cancer, metastasis and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: anaemia, diarrhoea, hypokalaemia, hyponatraemia, nausea, vomiting. OXALIPLATIN dosage: 110 MG/M2 Q 21 DAYS IV DRIP. During the same period patient was treated with DOCETAXOL. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5279859-4
Health Professional from UNITED STATES reported OXALIPLATIN problem on Mar 23, 2007. Female patient, weighting 271.0 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: arthritis infective, device related infection. OXALIPLATIN dosage: 85 MG/M2 Q 2 WK IV. During the same period patient was treated with LEUCOVORIN CALCIUM, AVASTIN. Patient was hospitalized. Patient recovered.

Oxaliplatin Side Effects Report #5283059-1
OXALIPLATIN problem was reported by a Pharmacist from UNITED STATES on Mar 28, 2007. Female patient, 47 years of age, weighting 146.0 lb, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: blood lactate dehydrogenase increased, dialysis, haematocrit decreased, haemoglobin decreased, platelet count decreased, renal failure. OXALIPLATIN dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

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