Oxaliplatin Safety Questions, Oxaliplatin Answers
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Oxaliplatin Safety Reports
Total Oxaliplatin reports: 178.Oxaliplatin FDA safety alerts: No.
Reported deaths: 50 Reported hospitalizations: 127.
Take Oxaliplatin Side Effects Survey or Share Your Oxaliplatin Story.
Reported Oxaliplatin Side Effects: diarrhoea, dehydration, nausea, vomiting, disease progression, pyrexia, fatigue, dyspnoea exertional, asthenia, haemoglobin decreased, hypotension.
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< Previous Showing 101-150 of 178 Next >
Oxaliplatin Side Effects Report #5102106-0Health Professional from UNITED STATES reported OXALIPLATIN problem on June 22, 2006. Female patient, 60 years of age, was diagnosed with chronic lymphocytic leukaemia refractory and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: disease progression. OXALIPLATIN dosage: unknown. During the same period patient was treated with RITUXAN, CYTARABINE, FLUDARABINE, SULFAMETHOXAZOLE, VALACYCLOVIR, LEVOFLOXACIN, PIOGLITAZONE, EXENATIDE. Patient was hospitalized. Patient died on 06/21/2006.
Oxaliplatin Side Effects Report #5105725-0
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Sept 12, 2006. Female patient, 65 years of age, was diagnosed with colorectal cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: thrombocytopenia, ventricular fibrillation. OXALIPLATIN dosage: unknown. During the same period patient was treated with ZOFRAN, COMPAZINE, PERCOCET, FLUOROURACIL. Patient died on 07/21/2006.
Oxaliplatin Side Effects Report #5105727-4
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on June 07, 2006. Female patient, weighting 189.6 lb, was diagnosed with pancreatic carcinoma metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: anorexia, blood calcium decreased, blood chloride decreased, blood potassium decreased, blood sodium decreased, disease progression, failure to thrive, oral intake reduced. OXALIPLATIN dosage: 190 MG (100 MG/M2) ON DAYS 1 AND 15. During the same period patient was treated with GEMCITABINE, AVASTIN. Patient was hospitalized. Patient died on 01/23/2006.
Oxaliplatin Side Effects Report #5108213-0
OXALIPLATIN problem was reported by a Consumer or non-health professional from UNITED STATES on June 05, 2006. Female patient, 48 years of age, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, back pain, cholecystitis, gallbladder disorder, neutrophil count decreased, operative haemorrhage, prothrombin time prolonged, white blood cell count decreased. OXALIPLATIN dosage: unknown. During the same period patient was treated with BENTYL, AVASTIN. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5110372-0
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on June 07, 2006. Female patient, weighting 189.6 lb, was diagnosed with pancreatic carcinoma metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: anorexia, blood calcium decreased, blood potassium decreased, blood sodium decreased, disease progression, failure to thrive, stomatitis. OXALIPLATIN dosage: 190 MG (100 MG/M2) ON DAYS 1 AND 15. During the same period patient was treated with GEMCITABINE, AVASTIN. Patient was hospitalized. Patient died on 01/23/2006.
Oxaliplatin Side Effects Report #5114201-0
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Sept 14, 2006. Female patient, weighting 62.83 lb, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: convulsion, reversible posterior leukoencephalopathy syndrome. OXALIPLATIN dosage: unknown. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5114231-9
Physician from UNITED STATES reported OXALIPLATIN problem on Sept 19, 2006. Female patient was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: catheter related infection, enteritis, haemoptysis, mucosal inflammation, neurotoxicity, platelet count decreased, pneumothorax, pseudomonal sepsis, septic embolus. OXALIPLATIN dosage: 85 MG/M2 (165 MG). During the same period patient was treated with LEUCOVORIN CALCIUM, ERBITUX, AVASTIN, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5117312-9
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Sept 11, 2006. Male patient, 56 years of age, weighting 176.0 lb, was diagnosed with pancreatic neoplasm and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: enteritis, febrile neutropenia, small intestinal obstruction. OXALIPLATIN dosage: 170 MG;Q2W;IV. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN CALCIUM, DEXAMETHASONE, LORAZEPAM, GRANISETRON, ACETAMINOFEN. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5117984-9
Health Professional from UNITED STATES reported OXALIPLATIN problem on Aug 03, 2006. Male patient, 51 years of age, was diagnosed with leukaemia and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: disease progression, hepatic failure. OXALIPLATIN dosage: unknown. During the same period patient was treated with FLUDARABINE, CYTARABINE. Patient was hospitalized. Patient died on 07/27/2006.
Oxaliplatin Side Effects Report #5119736-2
OXALIPLATIN problem was reported by a Health Professional from BRAZIL on Aug 29, 2006. Male patient was diagnosed with colorectal cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, sepsis. OXALIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, FOLINIC ACID, AVASTIN. Patient died on 08/12/2006.
Oxaliplatin Side Effects Report #5122678-X
Health Professional from UNITED STATES reported OXALIPLATIN problem on Oct 05, 2006. Male patient, 51 years of age, weighting 272.5 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: pyrexia. OXALIPLATIN dosage: 299 MG Q21 D IV. During the same period patient was treated with CAPECITABINE, NAPROSYN, HYDROCODONE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5126657-8
OXALIPLATIN problem was reported by a Pharmacist from UNITED STATES on Oct 12, 2006. Male patient, 74 years of age, weighting 201.1 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: rash. OXALIPLATIN dosage: 170MG, 170MG X 1 INTRAVEN. Patient recovered.
Oxaliplatin Side Effects Report #5126903-0
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on Oct 12, 2006. Male patient, weighting 206.0 lb, was diagnosed with neuroendocrine carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: anaemia, condition aggravated, fatigue. OXALIPLATIN dosage: 170 MG Q2WEEKS IV. During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL, BEVACIZUMAB, SANDOSTATIN LAR, LASIX, ACYCLOVIR, SPIRONOLACTONE, ARANESP. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5128965-3
OXALIPLATIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 16, 2006. Male patient, weighting 206.0 lb, was diagnosed with neuroendocrine carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: ascites, condition aggravated, fatigue, haemoglobin decreased, laboratory test interference, liver function test abnormal, performance status decreased. OXALIPLATIN dosage: 170 MG Q2WEEKS IV. During the same period patient was treated with LEUCOVORIN, BEVACIZUMAB, SANDOSTATIN LAR, LASIX, ACYCLOVIR, SPIRONOLACTONE, ARANESP. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5129853-9
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on Oct 06, 2006. Male patient, 65 years of age, was diagnosed with metastatic gastric cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: convulsion. OXALIPLATIN dosage: unknown. During the same period patient was treated with ATENOLOL, XANAX, PREVACID, DOXAZOSIN, BEVACIZUMAB. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5130855-7
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Oct 12, 2006. Male patient was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: dehydration, diarrhoea, fatigue, hypophosphataemia, hypotension, infection, neutrophil count decreased. OXALIPLATIN dosage: 85 MG/M2 (156 MG). During the same period patient was treated with LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5131480-4
Health Professional from UNITED KINGDOM reported OXALIPLATIN problem on Oct 13, 2006. Male patient, 63 years of age, weighting 198.4 lb, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest, diarrhoea, fall, fatigue. OXALIPLATIN dosage: unknown. During the same period patient was treated with XELODA. Patient was hospitalized. Patient died on 08/04/2006.
Oxaliplatin Side Effects Report #5134805-9
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Sept 19, 2006. Female patient was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: catheter related infection, enteritis, haemoptysis, mucosal inflammation, neurotoxicity, platelet count decreased, pneumothorax, pseudomonal sepsis, transient ischaemic attack. OXALIPLATIN dosage: 85 MG/M2 (165 MG). During the same period patient was treated with LEUCOVORIN CALCIUM, CETUXIMAB, BEVACIZUMAB, FLUOROURACIL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5134812-6
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on June 07, 2006. Female patient, weighting 189.6 lb, was diagnosed with pancreatic carcinoma metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: anorexia, disease progression, failure to thrive, laboratory test abnormal, stomatitis. OXALIPLATIN dosage: 190 MG (100 MG/M2) ON DAYS 1 AND 15. During the same period patient was treated with GEMCITABINE, BEVACIZUMAB. Patient was hospitalized. Patient died on 01/23/2006.
Oxaliplatin Side Effects Report #5136366-7
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Oct 23, 2006. Female patient, weighting 121.3 lb, was diagnosed with colorectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: agranulocytosis, asthenia, candidiasis, dehydration, diarrhoea, fatigue, oral intake reduced. OXALIPLATIN dosage: unknown. During the same period patient was treated with KYTRIL, IMODIUM, DEXAMETHASONE, ARANESP, ALOXI, IRINOTECAN, BEVACIZUMAB. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5140954-1
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on Oct 27, 2006. Male patient, weighting 206.0 lb, was diagnosed with neuroendocrine carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: ascites, failure to thrive, haemoglobin abnormal, liver function test abnormal, malignant neoplasm progression, neuroendocrine tumour, performance status decreased. OXALIPLATIN dosage: 170 MG Q2WEEKS IV. During the same period patient was treated with LEUCOVORIN, BEVACIZUMAB, SANDOSTATIN LAR, LASIX, ACYCLOVIR, SPIRONOLACTONE, ARANESP. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5142498-X
OXALIPLATIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 26, 2006. Male patient, weighting 205.9 lb, was diagnosed with neuroendocrine tumour and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: ascites, disease progression, failure to thrive, liver function test abnormal. OXALIPLATIN dosage: 170 MG (85 MG/M2) EVERY TWO WEEKS. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL, LEUCOVORIN, LOMOTIL, IMODIUM, ARANESP, SPIRONOLACTONE, ACYCLOVIR. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5144261-2
Health Professional from UNITED STATES reported OXALIPLATIN problem on Nov 02, 2006. Male patient, 72 years of age, weighting 149.9 lb, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: acute respiratory failure, aspiration, chronic obstructive pulmonary disease, constipation, dehydration, diarrhoea, haemodialysis, hypotension, hypoxia. OXALIPLATIN dosage: 130 MG DAY 1, 8 Q 21 DAYS IV. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient died on 10/24/2006.
Oxaliplatin Side Effects Report #5144788-3
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Nov 03, 2006. Male patient, weighting 140.2 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: pericardial effusion, pericardial effusion malignant, pleural effusion, pyrexia. OXALIPLATIN dosage: 85 MG/M2 IV D1 + 15. During the same period patient was treated with DOCETAXOL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5145790-8
Health Professional from JAPAN reported OXALIPLATIN problem on Oct 27, 2006. Female patient, 50 years of age, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: hepatic failure. OXALIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, CALCIUM LEVOFOLINATE. Patient died on 10/06/2006.
Oxaliplatin Side Effects Report #5146141-5
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Aug 21, 2006. Male patient, 72 years of age, weighting 149.9 lb, was diagnosed with oesophageal adenocarcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: constipation, dehydration, diarrhoea, hypotension, hypoxia, mental status changes, metabolic acidosis, mucosal inflammation, nausea. OXALIPLATIN dosage: 130 MG ON DAYS 1 AND 8 EVERY 21 DAYS. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient died on 10/24/2006.
Oxaliplatin Side Effects Report #5147799-7
Physician from UNITED STATES reported OXALIPLATIN problem on Nov 07, 2006. Female patient, 77 years of age, weighting 88.00 lb, was diagnosed with rectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, diarrhoea, frequent bowel movements, hypotension, nausea, pelvic pain, respiratory distress, vomiting. OXALIPLATIN dosage: 60 MG/M2 WEEKLY IV DRIP. During the same period patient was treated with SYNTHROID, ALBUTEROL, REGLAN, FLUOROURACIL, DOLASETRON, LORAZEPAM, PROCHLORPERAZINE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5151393-1
OXALIPLATIN problem was reported by a Pharmacist from UNITED STATES on Nov 10, 2006. Male patient, 56 years of age, weighting 210.1 lb, was diagnosed with neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: dyspnoea, flushing, infusion related reaction, paraesthesia oral, rash, urticaria. OXALIPLATIN dosage: 180 MG Q 2 WEEKS IV DRIP. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5152342-2
Physician from UNITED STATES reported OXALIPLATIN problem on Oct 23, 2006. Female patient, weighting 121.3 lb, was diagnosed with colorectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: agranulocytosis, dehydration, empyema, fatigue, pleural effusion, pleural infection, pneumonitis, respiratory failure. OXALIPLATIN dosage: unknown. During the same period patient was treated with KYTRIL, IMODIUM, DEXAMETHASONE, ARANESP, ALOXI, IRINOTECAN, BEVACIZUMAB. Patient was hospitalized. Patient died on 11/02/2006.
Oxaliplatin Side Effects Report #5153298-9
OXALIPLATIN problem was reported by a Health Professional from SPAIN on Nov 10, 2006. Male patient, weighting 173.5 lb, was diagnosed with neurological symptom and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: disease progression, thrombocytopenic purpura. OXALIPLATIN dosage: unknown. During the same period patient was treated with METOCLOPRAMID, LORAZEPAM, METAMIZOLE MAGNESIUM, LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient died on 11/12/2006.
Oxaliplatin Side Effects Report #5154134-7
Health Professional from UNITED STATES reported OXALIPLATIN problem on Nov 16, 2006. Male patient, weighting 184.0 lb, was diagnosed with colon cancer metastatic and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal distension, dehydration, diarrhoea, dyspnoea, nausea, small intestinal obstruction, vomiting. OXALIPLATIN dosage: 256.1 MG. Q3W, IV. During the same period patient was treated with BEVACIZUMAB, CLEOCIN T GEL, RESTORIL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5157719-7
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Oct 23, 2006. Female patient, weighting 121.3 lb, was diagnosed with colorectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: agranulocytosis, dehydration, empyema, fatigue, pleural effusion, pneumonitis, respiratory failure. OXALIPLATIN dosage: unknown. During the same period patient was treated with KYTRIL, IMODIUM, DEXAMETHASONE, ARANESP, ALOXI, IRINOTECAN, BEVACIZUMAB. Patient was hospitalized. Patient died on 11/02/2006.
Oxaliplatin Side Effects Report #5162015-8
Health Professional from SPAIN reported OXALIPLATIN problem on Nov 10, 2006. Male patient, weighting 173.5 lb, was diagnosed with neurological symptom and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: haemoglobin decreased, splenic haematoma, thrombocytopenic purpura. OXALIPLATIN dosage: unknown. During the same period patient was treated with METOCLOPRAMID, LORAZEPAM, METAMIZOLE MAGNESIUM, LEUCOVORIN CALCIUM, FLUOROURACIL. Patient was hospitalized. Patient died on 11/12/2006.
Oxaliplatin Side Effects Report #5163549-2
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Nov 28, 2006. Male patient, 75 years of age, weighting 125.7 lb, was diagnosed with rectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: fall, fatigue. OXALIPLATIN dosage: 40 MG/M2 IV. During the same period patient was treated with BEVACIZUMAB, FLUOROURACIL. Patient died on 11/16/2006.
Oxaliplatin Side Effects Report #5164322-1
Health Professional from UNITED STATES reported OXALIPLATIN problem on Nov 27, 2006. Male patient, 66 years of age, weighting 150.4 lb, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: anorexia, atrial flutter, dehydration, diarrhoea, dysphagia, nausea, tachycardia, vomiting. OXALIPLATIN dosage: 125 MG Q 7 DAYS IV. During the same period patient was treated with CAPECITABINE, TOPROL, LISINOPRIL, SUCRALFATE, NEXIUM, LIPITOR, PLAVIX, COLACE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5164711-5
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Nov 28, 2006. Male patient, 50 years of age, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, sick sinus syndrome. OXALIPLATIN dosage: 80 MG (40 MG/M2/WEEK) SCHEDULED FOR 5 WEEKS. During the same period patient was treated with FLUOROURACIL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5165969-9
Physician from UNITED STATES reported OXALIPLATIN problem on Aug 21, 2006. Male patient, 72 years of age, weighting 149.9 lb, was diagnosed with oesophageal adenocarcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: atrial tachycardia, constipation, dehydration, diarrhoea, hypotension, hypoxia, mental status changes, metabolic acidosis, mucosal inflammation. OXALIPLATIN dosage: 130 MG ON DAYS 1 AND 8 EVERY 21 DAYS. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient died on 10/24/2006.
Oxaliplatin Side Effects Report #5166701-5
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Dec 01, 2006. Male patient, 59 years of age, weighting 166.2 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: pain management. OXALIPLATIN dosage: 85MG/M2 DAYS 1 + 15. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5166914-2
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on Dec 04, 2006. Male patient, 56 years of age, weighting 280.0 lb, was diagnosed with colon cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: gait disturbance, nerve injury. OXALIPLATIN dosage: unknown. Patient recovered.
Oxaliplatin Side Effects Report #5169281-3
OXALIPLATIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 26, 2006. Male patient, weighting 205.9 lb, was diagnosed with neuroendocrine tumour and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: blood albumin decreased, brain natriuretic peptide increased, cyanosis, disease progression, failure to thrive, haemoglobin abnormal, metastases to liver, performance status decreased, pneumonia. OXALIPLATIN dosage: 170 MG (85 MG/M2) EVERY TWO WEEKS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, LOMOTIL, IMODIUM, ARANESP, SPIRONOLACTONE, ACYCLOVIR, LASIX. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5170403-9
Physician from JAPAN reported OXALIPLATIN problem on Dec 01, 2006. Female patient, 69 years of age, was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: angina pectoris. OXALIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEVOFOLINTE CALCIUM. Patient recovered.
Oxaliplatin Side Effects Report #5176954-5
OXALIPLATIN problem was reported by a Physician from UNITED STATES on Dec 12, 2006. Male patient, weighting 198.4 lb, was diagnosed with colon cancer stage iii and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: colon cancer, cryptococcosis, cytomegalovirus antibody positive, dyspnoea, fatigue, fungus sputum test positive, lung infiltration, metastases to lymph nodes, neuropathy. OXALIPLATIN dosage: 85MG/M2 EVERY 2WKS IV. Patient died on 09/05/2006.
Oxaliplatin Side Effects Report #5178971-8
Health Professional from UNITED STATES reported OXALIPLATIN problem on Dec 15, 2006. Male patient, 71 years of age, weighting 206.8 lb, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cellulitis, erythema, injection site reaction, oedema peripheral, pain in extremity. OXALIPLATIN dosage: 70 MG/M2 Q 7 DAYS IV. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5188058-6
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Dec 14, 2006. Male patient, weighting 170.6 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: brain oedema, headache. OXALIPLATIN dosage: 85 MG/M2. During the same period patient was treated with DOCETAXEL. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5190870-4
Health Professional from JAPAN reported OXALIPLATIN problem on Dec 13, 2006. Male patient, 75 years of age, was diagnosed with rectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: loss of consciousness. OXALIPLATIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5191247-8
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on Dec 20, 2006. Male patient, 71 years of age, weighting 213.4 lb, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: cellulitis. OXALIPLATIN dosage: 70 MG/M2 Q 7 DAYS IV. During the same period patient was treated with CAPECITABINE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5196695-8
Health Professional from UNITED STATES reported OXALIPLATIN problem on Dec 28, 2006. Male patient, 59 years of age, weighting 170.6 lb, was diagnosed with lung neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: bacillus infection, blood culture positive, staphylococcal infection. OXALIPLATIN dosage: 85MG/M2 DAYS 1 + 15 /Q28 IV. During the same period patient was treated with DOCETAXEL DAYS. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5385050-3
OXALIPLATIN problem was reported by a Health Professional from UNITED STATES on July 10, 2007. Male patient, 60 years of age, weighting 173.0 lb, was diagnosed with oesophageal carcinoma and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, blood potassium decreased, dehydration, diarrhoea, hypovolaemia. OXALIPLATIN dosage: 78 MG D1 - D8 IV. During the same period patient was treated with XELODA, TAXOTERE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5387671-0
Consumer or non-health professional from UNITED STATES reported OXALIPLATIN problem on July 12, 2007. Male patient, weighting 120.2 lb, was diagnosed with neoplasm malignant and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: dehydration, hypokalaemia, hyponatraemia, hypovolaemia. OXALIPLATIN dosage: 130MG/M2 Q 21 DAYS I.V.. During the same period patient was treated with CETUXIMAB, ACIPHEX, HYDROCHLOROTHIAZIDE, IRON SULPHATETHIAMIN COMPOUND, CELEBREX, TRIAMCINOLONE. Patient was hospitalized. Patient recovered.
Oxaliplatin Side Effects Report #5390866-3
OXALIPLATIN problem was reported by a Consumer or non-health professional from ITALY on July 02, 2007. Female patient, 76 years of age, was diagnosed with rectal cancer and was treated with OXALIPLATIN. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, carcinoembryonic antigen increased, disease progression, metastases to lung, metastases to salivary gland, metastases to skin, mucosal inflammation, rectal cancer metastatic, treatment noncompliance. OXALIPLATIN dosage: 100 MG/M2, ON DAY 1, REPEATED EVERY 14 DAYS,. During the same period patient was treated with FLUOROURACIL, RALTITREXED. Patient died on 05/01/2006.
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Drug Information: Oxaliplatin Injection
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607035.html
ox al" i pla' tinIMPORTANT WARNING:
| Oxaliplatin may cause severe allergic reactions. These allergic reactions may happen within a few minutes after you receive oxaliplatin and may cause death. Tell your doctor if you are allergic to oxaliplatin, carboplatin (Paraplatin), cisplatin (Platinol) or any other medications. If you experience any of the following symptoms, tell your doctor or other healthcare provider immediately: rash, hives, itching, reddening of the skin, difficulty breathing or swallowing, hoarseness, feeling as if your throat is closing, swelling of the lips and tongue, dizziness, lightheadness, or fainting. |
Why is this medication prescribed?
Oxaliplatin is used with other medications to treat advanced colon or rectal cancer (cancer that begins in the large intestine). Oxaliplatin is also used with other medications to prevent colon cancer from spreading in people who have had surgery to remove the tumor. Oxaliplatin is in a class of medications called platinum-containing antineoplastic agents. It works by killing cancer cells.
How should this medicine be used?
Oxaliplatin comes as a solution (liquid) to be injected into a vein. Oxaliplatin is administered by a doctor or nurse. It is usually given once every fourteen days.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before using oxaliplatin,
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention oral anticoagulants ('blood thinners') such as warfarin (Coumadin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had kidney disease.
- tell your doctor if you are pregnant or plan to become pregnant. Oxaliplatin may harm the fetus. You should use birth control to prevent pregnancy during your treatment with oxaliplatin. Talk to your doctor about types of birth control that will work for you.If you become pregnant while taking oxaliplatin, call your doctor. Do not breast-feed during your treatment with oxaliplatin.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using oxaliplatin.
- you should know that oxaliplatin may decrease your ability to fight infection. Stay away from people who are sick during your treatment with oxaliplatin.
- you should know that exposure to cold air or objects may make some of the side effects of oxaliplatin worse. You should not eat or drink anything colder than room temperature, touch any cold objects, go near air conditioners or freezers, wash your hands in cold water, or go outside in cold weather unless absolutely necessary for five days after you receive each dose of oxaliplatin. If you must go outside in cold weather, wear a hat, gloves, and a scarf, and cover your mouth and nose.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
Do not eat or drink anything that is colder than room temperature for five days after you receive each dose of oxaliplatin.
What should I do if I forget a dose?
Call your doctor as soon as possible if you are unable to keep an appointment to receive oxaliplatin. It is very important that you receive your treatment on schedule.
What side effects can this medication cause?
Oxaliplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- numbness, burning, or tingling in the fingers, toes, hands, feet, mouth, or throat
- pain in the hands or feet
- increased sensitivity, especially to cold
- decreased sense of touch
- nausea
- vomiting
- diarrhea
- constipation
- gas
- stomach pain
- heartburn
- sores in the mouth
- loss of appetite
- change in the ability to taste food
- weight gain or loss
- hiccups
- dry mouth
- muscle, back, or joint pain
- tiredness
- anxiety
- depression
- difficulty falling asleep or staying asleep
- hair loss
- dry skin
- redness or peeling of the skin on the hands and feet
- sweating
- flushing
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
- stumbling or loss of balance when walking
- difficulty with everyday activities such as writing or fastening buttons
- difficulty speaking
- strange feeling in the tongue
- tightening of the jaw
- chest pain or pressure
- cough
- shortness of breath
- sore throat, fever, chills, and other signs of infection
- pain, redness, or swelling in the place where oxaliplatin was injected
- pain when urinating
- decreased urination
- unusual bruising or bleeding
- nosebleed
- blood in urine
- vomit that is bloody or looks like coffee grounds
- bright red blood in stool
- black and tarry stools
- pale skin
- weakness
- problems with vision
- swelling of the arms, hands, feet, ankles, or lower legs
Oxaliplatin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- shortness of breath
- wheezing
- numbness or tingling in the fingers or toes
- vomiting
- chest pain
- slowed breathing
- slowed heartbeat
- tightening of the throat
- diarrhea
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to oxaliplatin.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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