Penfill Side Effects

Depression (8407980-8)
on May 18, 2006 Male patient from JAPAN , 71 years of age, was treated with Penfill 30r (insulin Human, Insulin Human Injection, Isophane)(View Usage). Patient experienced the following unwanted or unexpected effects: depression (What is depression?). Penfill 30r (insulin Human, Insulin Human Injection, Isophane) dosage: N/A.
Patient was taking other medications:

• DEPAS (ETIZOLAM) (View Depas (etizolam) Review and Depas (etizolam) Label )
• MAGMITT (MAGNESIUM OXIDE) (View Magmitt (magnesium Oxide) Review and Magmitt (magnesium Oxide) Label )
• MERISLON (BETAHISTINE MESILATE) (View Merislon (betahistine Mesilate) Review and Merislon (betahistine Mesilate) Label )
• PLETAL (50 Mg Milligram(s), Bid, Oral) (View Pletal Review and Pletal Label )
• MUCODYNE (CARBOCISTEINE) (View Mucodyne (carbocisteine) Review and Mucodyne (carbocisteine) Label )
• BASEN (VOGLIBOSE) (View Basen (voglibose) Review and Basen (voglibose) Label )

Acanthosis Nigricans, Injection Site Reaction (7134245-7)
Patient was taking Penfill R Chu (View Usage). Patient had the following side effects: acanthosis nigricans, injection site reaction on Nov 25, 2010 from JAPAN Additional patient health information: Male patient , 74 years of age, weighting 138.9 lb, was diagnosed with

• type 2 diabetes mellitus

and. Penfill R Chu dosage: 36 U, Qd.
Patient was taking other medications:

• PENFILL N CHU (12 U, Qd) (View Penfill N Chu Review and Penfill N Chu Label )

Anti-insulin Antibody Increased, Condition Aggravated, Diabetic Ketoacidotic Hyperglycaemic Coma, Hyperglycaemia, Hypoglycaemia, Psychiatric Symptom (7128379-0)
Adverse event was reported on Nov 17, 2010 by a Male patient taking Penfill 30r Chu (View Usage) (Dosage: Not Reported) was diagnosed with

• type 2 diabetes mellitus

and. Location: JAPAN , 78 years of age, After Penfill was administered, patient had the following side effects: anti-insulin antibody increased, condition aggravated, diabetic ketoacidotic hyperglycaemic coma, hyperglycaemia, hypoglycaemia, psychiatric symptom. Patient was hospitalized.

Acanthosis Nigricans, Injection Site Reaction (7125001-4)
on Nov 18, 2010 Male patient from JAPAN , 74 years of age, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill R Chu (View Usage). Patient experienced the following unwanted or unexpected effects: acanthosis nigricans, injection site reaction. Penfill R Chu dosage: 36 U, Qd.
Patient was taking other medications:

• PENFILL N CHU (12 U, Qd) (View Penfill N Chu Review and Penfill N Chu Label )

Anti-insulin Antibody Increased, Hypoglycaemia Unawareness (7110155-6)
on Nov 10, 2010 Female patient from JAPAN , 43 years of age, was diagnosed with

• diabetes mellitus

and was treated with Penfill 30r Chu(View Usage). Patient had the following side effects: anti-insulin antibody increased, hypoglycaemia unawareness. Penfill 30r Chu dosage: Unk, Bid.
Patient was taking other medications:

• NOVORAPID CHU FLEXPEN (Unk) (View Novorapid Chu Flexpen Review and Novorapid Chu Flexpen Label )
• LISPRO INSULIN (View Lispro Insulin Review and Lispro Insulin Label )

Anti-insulin Antibody Increased, Condition Aggravated, Diabetic Ketoacidotic Hyperglycaemic Coma, Hyperglycaemia, Hypoglycaemia, Psychiatric Symptom (7101775-3)
Patient was taking Penfill 30r Chu (View Usage). After Penfill was administered, patient had the following side effects: anti-insulin antibody increased, condition aggravated, diabetic ketoacidotic hyperglycaemic coma, hyperglycaemia, hypoglycaemia, psychiatric symptom on Nov 04, 2010 from JAPAN Additional patient health information: Male patient , 78 years of age, was diagnosed with

• type 2 diabetes mellitus

and. Penfill 30r Chu dosage: Not Reported. Patient was hospitalized.

Altered State Of Consciousness, Epilepsy, Hypoglycaemia, Retrograde Amnesia (6571030-9)
Adverse event was reported on Jan 28, 2010 by a Male patient taking Penfill N Chu (View Usage) (Dosage: Not Reported) was diagnosed with

• type 1 diabetes mellitus

and. Location: JAPAN , 39 years of age, Patient experienced the following unwanted or unexpected effects: altered state of consciousness, epilepsy (What is epilepsy?), hypoglycaemia, retrograde amnesia. Patient was hospitalized.

Oedema, Weight Increased (6567929-X)
on Jan 25, 2010 Female patient from JAPAN , 61 years of age, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill 30r Chu (View Usage). Patient had the following side effects: oedema, weight increased. Penfill 30r Chu dosage: Unk U, Unk.
Patient was taking other medications:

• ACTOS (/po) (View Actos Review and Actos Label )

Patient was hospitalized.

Altered State Of Consciousness, Epilepsy, Hypoglycaemia, Retrograde Amnesia (6550345-4)
on Jan 13, 2010 Male patient from JAPAN , 39 years of age, was diagnosed with

• type 1 diabetes mellitus

and was treated with Penfill N Chu(View Usage). After Penfill was administered, patient had the following side effects: altered state of consciousness, epilepsy (What is epilepsy?), hypoglycaemia, retrograde amnesia. Penfill N Chu dosage: Not Reported. Patient was hospitalized.

Hepatic Function Abnormal (6489625-X)
Patient was taking Penfill R Chu (View Usage). Patient experienced the following unwanted or unexpected effects: hepatic function abnormal on Dec 02, 2009 from JAPAN Additional patient health information: Female patient , 55 years of age, weighting 156.5 lb, was diagnosed with

• type 2 diabetes mellitus

and. Penfill R Chu dosage: Sliding Scale.
Patient was taking other medications:

• PENFILL N CHU (Sliding Scale) (View Penfill N Chu Review and Penfill N Chu Label )
• NOVOLIN R ((6+6+2+0) Iu, Qd) (View Novolin R Review and Novolin R Label )
• NOVOLIN N ((0+0+0+5) Iu, Qd) (View Novolin N Review and Novolin N Label )
• MAGMITT (990 Mg, Qd) (View Magmitt Review and Magmitt Label )
• ALOSENN /00476901/ (0.5 G, Qd) (View Alosenn /00476901/ Review and Alosenn /00476901/ Label )

Patient was hospitalized.

Hepatic Function Abnormal (6443449-8)
Adverse event was reported on Nov 06, 2009 by a Female patient taking Penfill R Chu (View Usage) (Dosage: Sliding Scale) was diagnosed with

• type 2 diabetes mellitus

and. Location: JAPAN , 55 years of age, weighting 156.5 lb, Patient had the following side effects: hepatic function abnormal.
Patient was taking other medications:

• PENFILL N CHU (Sliding Scale) (View Penfill N Chu Review and Penfill N Chu Label )
• NOVOLIN R ((6+6+2+0) Iu, Qd) (View Novolin R Review and Novolin R Label )
• NOVOLIN N ((0+0+0+5) Iu, Qd) (View Novolin N Review and Novolin N Label )
• MAGMITT (990 Mg, Qd) (View Magmitt Review and Magmitt Label )
• ALOSENN /00476901/ (0.5 G, Qd) (View Alosenn /00476901/ Review and Alosenn /00476901/ Label )

Patient was hospitalized.

Altered State Of Consciousness, Hypoglycaemic Coma (6412125-X)
on Oct 16, 2009 Female patient from JAPAN , 60 years of age, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill 50r Chu (View Usage). After Penfill was administered, patient had the following side effects: altered state of consciousness, hypoglycaemic coma. Penfill 50r Chu dosage: 16 Iu, Qd. Patient was hospitalized.

Altered State Of Consciousness, Hypoglycaemic Coma (6368311-0)
on Sep 11, 2009 Female patient from JAPAN , 60 years of age, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill 50r Chu(View Usage). Patient experienced the following unwanted or unexpected effects: altered state of consciousness, hypoglycaemic coma. Penfill 50r Chu dosage: 16 Iu, Qd. Patient was hospitalized.

Hypoglycaemia, Hypoglycaemic Coma, Intentional Overdose, Suicide Attempt (6335015-X)
Patient was taking Penfill 30r Chu (View Usage). Patient had the following side effects: hypoglycaemia, hypoglycaemic coma, intentional overdose, suicide attempt on Aug 19, 2009 from JAPAN Additional patient health information: Female patient , weighting 125.7 lb, was diagnosed with

• type 2 diabetes mellitus

and. Penfill 30r Chu dosage: 10+12+0 Iu, Qd. Patient was hospitalized.

Hypoglycaemia, Suicide Attempt (6301557-6)
Adverse event was reported on Jul 30, 2009 by a Male patient taking Penfill N Chu (View Usage) (Dosage: 13 Iu, Qd) was diagnosed with

• type 1 diabetes mellitus

and. Location: JAPAN , 37 years of age, After Penfill was administered, patient had the following side effects: hypoglycaemia, suicide attempt. Patient was hospitalized.

Hypoglycaemia, Suicide Attempt (6273527-8)
on Jul 10, 2009 Male patient from JAPAN , 37 years of age, was diagnosed with

• type 1 diabetes mellitus

and was treated with Penfill N Chu (View Usage). Patient experienced the following unwanted or unexpected effects: hypoglycaemia, suicide attempt. Penfill N Chu dosage: Unk Iu, Unk. Patient was hospitalized.

Blood Glucose Increased, Injection Site Reaction (6218171-3)
on May 28, 2009 Male patient from JAPAN , 50 years of age, weighting 163.1 lb, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill R Chu(View Usage). Patient had the following side effects: blood glucose increased, injection site reaction. Penfill R Chu dosage: 4-4-4.
Patient was taking other medications:

• PENFILL 30R CHU (14-18 Iu) (View Penfill 30r Chu Review and Penfill 30r Chu Label )
• LANTUS (View Lantus Review and Lantus Label )
• METFORMIN HYDROCHLORIDE (500 Mg, Qd) (View Metformin Hydrochloride Review and Metformin Hydrochloride Label )
• ALOTEC (5 Mg, Unk) (View Alotec Review and Alotec Label )

Patient was hospitalized.

Anti-insulin Antibody, Autoantibody Positive, Bladder Perforation, Blood Glucose Fluctuation (6139560-1)
Patient was taking Penfill 30r Chu (View Usage). After Penfill was administered, patient had the following side effects: anti-insulin antibody, autoantibody positive, bladder perforation, blood glucose fluctuation on Mar 19, 2009 from JAPAN Additional patient health information: Female patient , 58 years of age, was diagnosed with

• type 2 diabetes mellitus

and. Penfill 30r Chu dosage: Unk, Unk. Patient was hospitalized.

Anti-insulin Antibody Increased, Hypoglycaemia (6105104-3)
Adverse event was reported on Feb 24, 2009 by a Female patient taking Penfill R Chu (View Usage) (Dosage: N/A) was diagnosed with

• type 2 diabetes mellitus

and. Location: JAPAN , 70 years of age, weighting 154.3 lb, Patient experienced the following unwanted or unexpected effects: anti-insulin antibody increased, hypoglycaemia.
Patient was taking other medications:

• PENFILL 30R CHU (View Penfill 30r Chu Review and Penfill 30r Chu Label )
• HUMALOG (View Humalog Review and Humalog Label )
• LANTUS (View Lantus Review and Lantus Label )

Patient was hospitalized.

Anti-insulin Antibody, Hypoglycaemia (5972661-7)
on Nov 20, 2008 Male patient from JAPAN , 68 years of age, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill 30r Chu (View Usage). Patient had the following side effects: anti-insulin antibody, hypoglycaemia. Penfill 30r Chu dosage: (20-0-10).
Patient was taking other medications:

• PENFILL R CHU (Not Reported) (View Penfill R Chu Review and Penfill R Chu Label )
• PENFILL 10R CHU (Not Reported) (View Penfill 10r Chu Review and Penfill 10r Chu Label )
• PENFILL N CHU (Not Reported) (View Penfill N Chu Review and Penfill N Chu Label )

Patient was hospitalized.

Hypoglycaemic Coma, Intentional Overdose, Suicide Attempt (5951716-7)
on Nov 04, 2008 Male patient from JAPAN , 65 years of age, weighting 130.1 lb, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill 50r Chu(View Usage). After Penfill was administered, patient had the following side effects: hypoglycaemic coma, intentional overdose, suicide attempt. Penfill 50r Chu dosage: N/A.
Patient was taking other medications:

• PENFILL R CHU (View Penfill R Chu Review and Penfill R Chu Label )
• INSULIN (View Insulin Review and Insulin Label )
• SINLESTAL (750 Mg, Qd) (View Sinlestal Review and Sinlestal Label )
• PENFILL 30R CHU (View Penfill 30r Chu Review and Penfill 30r Chu Label )

Anorexia Nervosa, Hypoglycaemia (5795866-7)
Patient was taking Penfill 30r Chu (View Usage). Patient experienced the following unwanted or unexpected effects: anorexia nervosa, hypoglycaemia on Jun 19, 2008 from JAPAN Additional patient health information: Female patient , weighting 149.9 lb, was diagnosed with

• type 2 diabetes mellitus

and. Penfill 30r Chu dosage: N/A.
Patient was taking other medications:

• NOVORAPID CHU (View Novorapid Chu Review and Novorapid Chu Label )
• GLUFAST (30 Mg, Qd) (View Glufast Review and Glufast Label )

Patient was hospitalized.

Hepatic Function Abnormal (5788726-9)
Adverse event was reported on Jun 16, 2008 by a Female patient taking Penfill N Chu (View Usage) (Dosage: 8 Iu, Qd) was diagnosed with

• hyperglycaemia

and. Location: JAPAN , 57 years of age, Patient had the following side effects: hepatic function abnormal.
Patient was taking other medications:

• PENFILL R CHU (24 Iu, Qd) (View Penfill R Chu Review and Penfill R Chu Label )
• HUMALOG (24 U, Qd) (View Humalog Review and Humalog Label )

Blood Glucose Fluctuation, Hypoglycaemia (5781391-6)
on Jun 10, 2008 Female patient from JAPAN , 62 years of age, weighting 114.6 lb, was diagnosed with

• latent autoimmune diabetes in adults

and was treated with Penfill 30r Chu (View Usage). After Penfill was administered, patient had the following side effects: blood glucose fluctuation, hypoglycaemia. Penfill 30r Chu dosage: 20-0-10 Iu, Qd. Patient was hospitalized.

Anorexia Nervosa, Hypoglycaemia (5775341-6)
on Jun 06, 2008 Female patient from JAPAN , weighting 149.9 lb, was diagnosed with

• type 2 diabetes mellitus

and was treated with Penfill 30r Chu(View Usage). Patient experienced the following unwanted or unexpected effects: anorexia nervosa, hypoglycaemia. Penfill 30r Chu dosage: N/A.
Patient was taking other medications:

• NOVORAPID CHU (View Novorapid Chu Review and Novorapid Chu Label )
• GLUFAST (30 Mg, Qd) (View Glufast Review and Glufast Label )

Patient was hospitalized.