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Peridex Side Effects

Common Peridex Side Effects


The most commonly reported Peridex side effects (click to view or check a box to report):

Ageusia (5)
Vomiting (3)
Anxiety (3)
Osteonecrosis Of Jaw (3)
Type 2 Diabetes Mellitus (2)
Spinal Osteoarthritis (2)
Infection (2)
Osteoporosis (2)
Pain (2)
Pulmonary Embolism (2)
Osteolysis (2)
Osteoarthritis (2)
Gingival Hyperplasia (2)
Dizziness (2)
Dehydration (2)
Nausea (2)
Swelling Face (1)
Tongue Ulceration (1)
Osteomyelitis (1)
Tooth Deposit (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Peridex Side Effects Reported to FDA

The following Peridex reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Peridex on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Convulsion, Movement Disorder, Heart Rate Increased, Hypoaesthesia, Respiratory Disorder, Tremor
This is a report of a 59-year-old male patient (weight: NA) from US, suffering from the following symptoms/conditions: dental disorder prophylaxis, who was treated with Peridex ( Chlorhexidine Gluconate) 0.12% 3m (dosage: Oral Rinse Morning And Night Twice Daily Oral Rinse, start time: Mar 07, 2014), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
  • Convulsion
  • Movement Disorder
  • Heart Rate Increased
  • Hypoaesthesia
  • Respiratory Disorder
  • Tremor
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex ( Chlorhexidine Gluconate) 0.12% 3m treatment in male patients, resulting in convulsion side effect.

Ageusia
This report suggests a potential Peridex Ageusia side effect(s) that can have serious consequences. A 87-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: periodontal disease and used Peridex (dosage: 1/2 Oz 2 X Day Po) starting May 14, 2012. Soon after starting Peridex the patient began experiencing various side effects, including:
  • Ageusia
Drugs used concurrently: NA. Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as ageusia, may still occur.

Oral Pain, Lip Erosion, Tongue Ulceration, Glossitis, Stomatitis
This Oral Pain, Lip Erosion, Tongue Ulceration, Glossitis, Stomatitis problem was reported by a consumer or non-health professional from US. A 67-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: periodontal disease. On NS this consumer started treatment with Peridex (dosage: NA). The following drugs were being taken at the same time: NA. When commencing Peridex, the patient experienced the following unwanted symptoms/side effects:
  • Oral Pain
  • Lip Erosion
  • Tongue Ulceration
  • Glossitis
  • Stomatitis
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as oral pain, may become evident only after a product is in use by the general population.

Fall, Decubitus Ulcer, Pelvic Pain, Pancytopenia, Clostridium Difficile Colitis, Urinary Tract Infection, Renal Failure Acute, Vomiting, Metastases To Bone
This is a report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Peridex /00133002/ (dosage: NA) starting May 01, 2012. Concurrently used drugs:
  • Neurontin (300 Mg, Tid)
  • Oxycodone Hydrochloride (5 Mg, Prn)
  • Protonix (40 Mg, Qd)
  • Velcade (2.7 Mg, Cyclic)
  • Velcade (2.7 Mg, Cyclic)
  • Antibiotics
  • Decadron (40 Mg, Cyclic)
  • Cytoxan
Soon after that, the consumer experienced the following side effects:
  • Fall
  • Decubitus Ulcer
  • Pelvic Pain
  • Pancytopenia
  • Clostridium Difficile Colitis
  • Urinary Tract Infection
  • Renal Failure Acute
  • Vomiting
  • Metastases To Bone
The patient was hospitalized. This opens a possibility that Peridex /00133002/ treatment could cause the above reactions, including fall, and some female subjects may be more susceptible.


Dehydration, Rash, Vomiting, Speech Disorder, Nausea, Skin Ulcer
A 61-year-old male patient (weight: NA) from UNITED STATES with the following symptoms/conditions: NA started Peridex treatment (dosage: 12%) on Nov 02, 2011. Soon after starting Peridex treatment, the subject experienced various side effects, including:
  • Dehydration
  • Rash
  • Vomiting
  • Speech Disorder
  • Nausea
  • Skin Ulcer
Concurrently used drugs:
  • Robitussin Dm (5-100mg/5ml Syrup 4hrs)
  • Sinequan (10mg/ml Every 4hrs)
  • Ativan (1df = 1tab .5mg Every 4hrs)
  • Compazine (1df= 1tab Of 10mg Every 6hrs)
  • Ativan (1df = 1tab .5mg Every 4hrs)
  • Prevacid (1df = 1cap)
  • Silvadene
  • Tylenol (1df = 1tab 8hr Sustained Release 2/d Prn)
The patient was hospitalized. This finding indicates that some male patients could be more vulnerable to Peridex.

Swelling Face, Hypertension, Liver Disorder, Haemoptysis, Osteoarthritis, Osteonecrosis Of Jaw, Ilium Fracture, Haematemesis, Osteoporosis
A female patient from UNITED STATES (weight: NA) experienced symptoms, such as: NA and was treated with Peridex(dosage: NA). The treatment was initiated on NS. After that a consumer reported the following side effect(s):
  • Swelling Face
  • Hypertension
  • Liver Disorder
  • Haemoptysis
  • Osteoarthritis
  • Osteonecrosis Of Jaw
  • Ilium Fracture
  • Haematemesis
  • Osteoporosis
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Peridex efficacy:
  • Aspirin
  • Simvastatin (20 Mg, Unk)
  • Metformin Hcl (500 Mg, Unk)
  • Multi-vitamins
  • Femara (2.5 Mg, Unk)
  • Zocor
  • Amaryl (2 Mg, Unk)
  • Anticoagulants


Ageusia
In this report, Peridex was administered for the following condition: gingivitis.A 81-year-old female consumer from UNITED STATES (weight: NA) started Peridex treatment (dosage: NA) on Jan 05, 2012.Sometime after starting the treatment, the patient complained of the following side effect(s):
  • Ageusia
A possible interaction with other drugs could have contributed to this reaction: NA.Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Peridex treatment could be related to the listed above side effect(s).

Osteonecrosis Of Jaw, Anxiety, Osteolysis, Gout, Haematochezia, Pulmonary Embolism, Type 2 Diabetes Mellitus, Osteoporosis, Spinal Osteoarthritis
This is a report of the following Peridex side effect(s):
  • Osteonecrosis Of Jaw
  • Anxiety
  • Osteolysis
  • Gout
  • Haematochezia
  • Pulmonary Embolism
  • Type 2 Diabetes Mellitus
  • Osteoporosis
  • Spinal Osteoarthritis
A female patient from UNITED STATES (weight: NA) presented with the following condition: NA and received a treatment with Peridex (dosage: NA) starting: May 01, 2007.The following concurrently used drugs could have generated interactions:
  • Simvastatin
  • Omeprazole
  • Neurontin
  • Lyrica
  • Lidocaine
  • Procrit /00909301/
  • Glipizide
  • Hydrochlorothiazide
This report suggests that a Peridex treatment could be associated with the listed above side effect(s).

Ischaemia, Anxiety, Bone Loss, Influenza, Nodule, Spinal Osteoarthritis, Gastrointestinal Mucosal Disorder, Life Expectancy Shortened, Anhedonia
This Peridex report was submitted by a female consumer from UNITED STATES (weight: NA). The patient was diagnosed with: NA and Peridex was administered (dosage: NA) starting: Feb 18, 2005. The consumer developed a set of symptoms:
  • Ischaemia
  • Anxiety
  • Bone Loss
  • Influenza
  • Nodule
  • Spinal Osteoarthritis
  • Gastrointestinal Mucosal Disorder
  • Life Expectancy Shortened
  • Anhedonia
Other drugs used simultaneously:
  • Simavastatin (Unk)
  • Macrobid (100 Mg, Unk)
  • Tannic Acid (Unk)
  • Chlorhexidine Gluconate (Unk)
  • Diphenhydramine Hcl (50 Mg, Unk)
  • Tretinoin (Unk)
  • Bactrim
  • Zen
Those unexpected symptoms could be linked to a Peridex treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

Activities Of Daily Living Impaired, Haemorrhage, Asthenia
This is a report of a possible correlation between Peridex use and the following symptoms/side effect(s):
  • Activities Of Daily Living Impaired
  • Haemorrhage
  • Asthenia
which could contribute to an assessment of Peridex risk profile.A 92-year-old female consumer from CANADA (weight: NA) was suffering from surgery and was treated with Peridex (dosage: NA) starting Oct 01, 2008.Other concurrent medications: NA.

Osteonecrosis Of Jaw, Paraesthesia, Pain, Nephrolithiasis, Panic Attack, Infection, Type 2 Diabetes Mellitus, Deep Vein Thrombosis, Anxiety
A 70-year-old female patient from UNITED STATES (weight: NA) presented with the following symptoms: NA and after a treatment with Peridex (dosage: NA) experienced the following side effect(s):
  • Osteonecrosis Of Jaw
  • Paraesthesia
  • Pain
  • Nephrolithiasis
  • Panic Attack
  • Infection
  • Type 2 Diabetes Mellitus
  • Deep Vein Thrombosis
  • Anxiety
The treatment was started on May 01, 2007. Peridex was used in combination with the following drugs:
  • Coumadin
  • Simvastatin
  • Zometa (4 Mg, Qmo)
  • Clonazepam
  • Revlimid
  • Hydrochlorothiazide
  • Metoprolol Tartrate
  • Glipizide
This report could alert potential Peridex consumers.

Gingival Erythema, Pain, Decreased Interest, Osteolysis, Spinal Disorder, Metastases To Spine, Osteoarthritis, Bone Disorder, Gingival Infection
In this report, a female patient from UNITED STATES (weight: NA) was affected by a possible Peridex side effect.The patient was diagnosed with NA. After a treatment with Peridex (dosage: NA, start date: Oct 22, 2004), the patient experienced the following side effect(s):
  • Gingival Erythema
  • Pain
  • Decreased Interest
  • Osteolysis
  • Spinal Disorder
  • Metastases To Spine
  • Osteoarthritis
  • Bone Disorder
  • Gingival Infection
The following simultaneously used drugs could have led to this reaction:
  • Diovan (80 Mg, Qd)
  • Capecitabine
  • Amoxicillin (500 Mg, Tid)
  • Amoxicillin (500 Mg, Tid)
  • Amoxicillin (500 Mg, Tid)
  • Levaquin
  • Oxycodone Hcl
  • Neupogen
The findings here stress that side effects should be taken into consideration when evaluating a Peridex treatment.

Renal Papillary Necrosis, Infection, Vomiting, Urinary Retention, Constipation, Dehydration, Abdominal Pain, Weight Decreased, Haematuria
This is a report of a male patient from UNITED STATES (weight: NA), who used Peridex (dosage: NA) for a treatment of NA. After starting a treatment on Apr 20, 2006, the patient experienced the following side effect(s):
  • Renal Papillary Necrosis
  • Infection
  • Vomiting
  • Urinary Retention
  • Constipation
  • Dehydration
  • Abdominal Pain
  • Weight Decreased
  • Haematuria
The following drugs could possibly have interacted with the Peridex treatment
  • Lemon (Unk)
  • Bisacodyl
  • Exjade (1875 Mg, Daily)
  • Blood Transfusion, Auxiliary Products
  • Keppra (8 Ml, Bid)
  • Folic Acid (1 Mg, Daily)
  • Zantac (10 Ml, Bid)
  • Drisdol (5 Ml, Every 3 Months)
The patient was hospitalized.Taken together, these observations suggest that a Peridex treatment could be related to side effect(s), such as Renal Papillary Necrosis, Infection, Vomiting, Urinary Retention, Constipation, Dehydration, Abdominal Pain, Weight Decreased, Haematuria.

Cellulitis, Discomfort, Gingival Bleeding, Oropharyngeal Pain, Myalgia, Feeling Jittery, Dyspnoea, Decreased Appetite, Gingival Hyperplasia
This cellulitis side effect was reported by a physician from UNITED STATES. A female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Peridex (dosage: NA), which was started on Feb 18, 2005. Concurrently used drugs:
  • Tamoxifen
  • Simvastatin (20 , Daily)
  • Evoxac (30mg)
  • Tobradex (Unk)
  • Pravachol (20 Mg)
  • Macrobid (100 Mg)
  • Meclizine (12.5 Mg)
  • Chlorhexidine Gluconate (Unk)
When starting to take Peridex the consumer reported the following symptoms:
  • Cellulitis
  • Discomfort
  • Gingival Bleeding
  • Oropharyngeal Pain
  • Myalgia
  • Feeling Jittery
  • Dyspnoea
  • Decreased Appetite
  • Gingival Hyperplasia
These side effects may potentially be related to Peridex.

Tooth Discolouration
This is a Peridex side effect report of a 56-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: dental operation, who was treated with Peridex (dosage:1 Tbsp 3x Daily Top, start time: Mar 23, 2011), combined with: NA., and developed a serious reaction and a tooth discolouration side effect. The patient presented with:
  • Tooth Discolouration
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Peridex treatment in female patients suffering from dental operation, resulting in tooth discolouration.

Injury, Osteomyelitis, Fistula, Gingival Hyperplasia, Malaise, Laryngeal Oedema, Dizziness, Hiatus Hernia, Periodontal Disease
This report suggests a potential Peridex injury side effect(s) that can have serious consequences. A female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Peridex (dosage: NA) starting Mar 22, 2004. Soon after starting Peridex the patient began experiencing various side effects, including:
  • Injury
  • Osteomyelitis
  • Fistula
  • Gingival Hyperplasia
  • Malaise
  • Laryngeal Oedema
  • Dizziness
  • Hiatus Hernia
  • Periodontal Disease
Drugs used concurrently:
  • Simvastatin (20 , Daily)
  • Fosamax (Unk)
  • Levaquin (500 Mg)
  • Alprazolam (0.25 Mg)
  • Tretinoin (Unk)
  • Faslodex
  • Propranolol Hydrochloride
  • Citalopram Hydrobromide
Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as injury, may still occur.

Pulmonary Embolism, Altered State Of Consciousness, Haemorrhoids, Prostate Cancer, Depression, Hypophagia, Prostatic Specific Antigen Increased, Atelectasis, Stress
This pulmonary embolism problem was reported by a consumer or non-health professional from UNITED STATES. A male patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jan 07, 2008 a consumer started treatment with Peridex (dosage: Unk). The following drugs/medications were being taken at the same time:
  • Hydrocort
  • Apap Tab
  • Dolasetron
  • Relafen (750 Mg Every 12 Hours)
  • Pantoprazole
  • Loperamide
  • Acyclovir (200 Mg, Unk)
  • Oramorph Sr (Unk)
When commencing Peridex, the patient experienced the following unwanted symptoms /side effects:
  • Pulmonary Embolism
  • Altered State Of Consciousness
  • Haemorrhoids
  • Prostate Cancer
  • Depression
  • Hypophagia
  • Prostatic Specific Antigen Increased
  • Atelectasis
  • Stress
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as pulmonary embolism, may become evident only after a product is in use by the general population.

Diarrhoea, Ageusia, Abdominal Discomfort, Muscular Weakness, Headache, Nausea, Dizziness, Somnolence
This is a Peridex side effect report of a male patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: gingivitis and was treated with Peridex (dosage: 15ml Once Daily Dental) starting Feb 11, 2011. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Diarrhoea
  • Ageusia
  • Abdominal Discomfort
  • Muscular Weakness
  • Headache
  • Nausea
  • Dizziness
  • Somnolence
This opens a possibility that Peridex could cause diarrhoea and that some male patients may be more susceptible.

Sensitivity Of Teeth, Tooth Deposit
A 67-year-old male patient (weight: NA) from UNITED STATES with the following symptoms: periodontal disease started Peridex treatment (dosage: Capfull -1-2 Ml- Twice Per Day Po) on Apr 20, 2010. Soon after starting Peridex treatment, the consumer experienced several side effects, including:
  • Sensitivity Of Teeth
  • Tooth Deposit
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Peridex side effects, such as sensitivity of teeth.

Blood Pressure Increased
This blood pressure increased side effect was reported by a consumer or non-health professional from UNITED STATES. A 73-year-old female patient (weight:NA) experienced the following symptoms/conditions: periodontal disease.The patient was prescribed Peridex (dosage: Applies Topically To Two Teeth One Time Po), which was started on Aug 05, 2008. Concurrently used drugs: NA..When starting to take Peridex the consumer reported symptoms, such as:
  • Blood Pressure Increased
These side effects may potentially be related to Peridex.

Ageusia
This is a report of a 53-year-old male patient (weight: NA) from UNITED STATES, suffering from the following symptoms/conditions: gingivitis, who was treated with Peridex (dosage: Oral Rinse Once Daily, start time: Apr 01, 2003), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
  • Ageusia
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex treatment in male patients, resulting in ageusia side effect.

Ageusia
This report suggests a potential Peridex Ageusia side effect(s) that can have serious consequences. A 53-year-old male patient (weight: NA) from UNITED STATES was diagnosed with the following symptoms/conditions: gingival disorder and used Peridex (dosage: .15 Ml Once @ Night Every Day) starting Mar 01, 2003. Soon after starting Peridex the patient began experiencing various side effects, including:
  • Ageusia
Drugs used concurrently: NA. Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as ageusia, may still occur.



Keep Track of Side Effects

Note Your Observations

It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


    Discuss Peridex Side Effects

    Did You Have a Peridex Side Effect?

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    How Effective is Peridex for You?

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    Peridex Safety Alerts, Active Ingredients, Usage Information

    NDC48878-0620
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NamePeridex
    Namechlorhexidine gluconate
    Dosage FormRINSE
    RouteORAL
    On market since19860813
    Labeler3M ESPE Dental Products
    Active Ingredient(s)CHLORHEXIDINE GLUCONATE
    Strength(s)1.2
    Unit(s)mg/mL
    Pharma ClassDecreased Cell Wall Integrity [PE]

    Peridex Dosage, Warnings, Usage.

    Side Effects reported to FDA: 22

    Peridex safety alerts: No

    Reported hospitalizations: 2

    Latest Peridex clinical trials