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Peridex Side Effects

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Common Peridex Side Effects


The most commonly reported Peridex side effects (click to view or check a box to report):

Ageusia (5)
Vomiting (3)
Anxiety (3)
Osteonecrosis Of Jaw (3)
Type 2 Diabetes Mellitus (2)
Spinal Osteoarthritis (2)
Infection (2)
Osteoporosis (2)
Pain (2)
Pulmonary Embolism (2)
Osteolysis (2)
Osteoarthritis (2)
Gingival Hyperplasia (2)
Dizziness (2)
Dehydration (2)
Nausea (2)
Swelling Face (1)
Tongue Ulceration (1)
Osteomyelitis (1)
Tooth Deposit (1)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Peridex Side Effects Reported to FDA



Peridex Side Effect Report#9995824
Convulsion, Movement Disorder, Heart Rate Increased, Hypoaesthesia, Respiratory Disorder, Tremor
This is a report of a 59-year-old male patient (weight: NA) from US, suffering from the following health symptoms/conditions: dental disorder prophylaxis, who was treated with Peridex ( Chlorhexidine Gluconate) 0.12% 3m (dosage: Oral Rinse Morning And Night Twice Daily Oral Rinse, start time:
Mar 07, 2014), combined with: NA. and developed a serious reaction and side effect(s): Convulsion, Movement Disorder, Heart Rate Increased, Hypoaesthesia, Respiratory Disorder, Tremor after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex ( Chlorhexidine Gluconate) 0.12% 3m treatment in male patients, resulting in Convulsion side effect.
Peridex Side Effect Report#8957400
Ageusia
This report suggests a potential Peridex Ageusia side effect(s) that can have serious consequences. A 87-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: periodontal disease and used Peridex (dosage: 1/2 Oz 2 X Day Po) starting
May 14, 2012. After starting Peridex the patient began experiencing various side effects, including: AgeusiaAdditional drugs used concurrently: NA. Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Ageusia, may still occur.
Peridex Side Effect Report#8839374
Oral Pain, Lip Erosion, Tongue Ulceration, Glossitis, Stomatitis
This Oral Pain problem was reported by a consumer or non-health professional from US. A 67-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: periodontal disease. On NS this consumer started treatment with Peridex (dosage: NA). The following drugs were being taken at the same time: NA. When using Peridex, the patient experienced the following unwanted symptoms/side effects: Oral Pain, Lip Erosion, Tongue Ulceration, Glossitis, StomatitisAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Oral Pain, may become evident only after a product is in use by the general population.
Peridex Side Effect Report#8381216-9
Fall, Decubitus Ulcer, Pelvic Pain, Pancytopenia, Clostridium Difficile Colitis, Urinary Tract Infection, Renal Failure Acute, Vomiting, Metastases To Bone
This Fall side effect was reported by a physician from United States. A female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Peridex /00133002/ (drug dosage: NA), which was initiated on
May 01, 2012. Concurrently used drugs:
  • Neurontin (300 Mg, Tid)
  • Oxycodone Hydrochloride (5 Mg, Prn)
  • Protonix (40 Mg, Qd)
  • Velcade (2.7 Mg, Cyclic)
  • Velcade (2.7 Mg, Cyclic)
  • Antibiotics
  • Decadron (40 Mg, Cyclic)
  • Cytoxan
.After starting to take Peridex /00133002/ the consumer reported adverse symptoms, such as: Fall, Decubitus Ulcer, Pelvic Pain, Pancytopenia, Clostridium Difficile Colitis, Urinary Tract Infection, Renal Failure Acute, Vomiting, Metastases To BoneThese side effects may potentially be related to Peridex /00133002/. The patient was hospitalized.
Peridex Side Effect Report#8228167-8
Dehydration, Rash, Vomiting, Speech Disorder, Nausea, Skin Ulcer
This is a report of a 61-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Peridex (dosage: 12%, start time:
Nov 02, 2011), combined with:
  • Robitussin Dm (5-100mg/5ml Syrup 4hrs)
  • Sinequan (10mg/ml Every 4hrs)
  • Ativan (1df = 1tab .5mg Every 4hrs)
  • Compazine (1df= 1tab Of 10mg Every 6hrs)
  • Ativan (1df = 1tab .5mg Every 4hrs)
  • Prevacid (1df = 1cap)
  • Silvadene
  • Tylenol (1df = 1tab 8hr Sustained Release 2/d Prn)
and developed a serious reaction and side effect(s): Dehydration, Rash, Vomiting, Speech Disorder, Nausea, Skin Ulcer after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex treatment in male patients, resulting in Dehydration side effect. The patient was hospitalized.
Peridex Side Effect Report#8198324-8
Swelling Face, Hypertension, Liver Disorder, Haemoptysis, Osteoarthritis, Osteonecrosis Of Jaw, Ilium Fracture, Haematemesis, Osteoporosis
This report suggests a potential Peridex Swelling Face side effect(s) that can have serious consequences. A female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: NA and used Peridex (dosage: NA) starting NS. After starting Peridex the patient began experiencing various side effects, including: Swelling Face, Hypertension, Liver Disorder, Haemoptysis, Osteoarthritis, Osteonecrosis Of Jaw, Ilium Fracture, Haematemesis, OsteoporosisAdditional drugs used concurrently:
  • Aspirin
  • Simvastatin (20 Mg, Unk)
  • Metformin Hcl (500 Mg, Unk)
  • Multi-vitamins
  • Femara (2.5 Mg, Unk)
  • Zocor
  • Amaryl (2 Mg, Unk)
  • Anticoagulants
Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Swelling Face, may still occur.
Peridex Side Effect Report#8181625-7
Ageusia
This Ageusia problem was reported by a consumer or non-health professional from United States. A 81-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: gingivitis. On
Jan 05, 2012 this consumer started treatment with Peridex (dosage: NA). The following drugs were being taken at the same time: NA. When using Peridex, the patient experienced the following unwanted symptoms/side effects: AgeusiaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Ageusia, may become evident only after a product is in use by the general population.
Peridex Side Effect Report#7917882-9
Osteonecrosis Of Jaw, Anxiety, Osteolysis, Gout, Haematochezia, Pulmonary Embolism, Type 2 Diabetes Mellitus, Osteoporosis, Spinal Osteoarthritis
This Osteonecrosis Of Jaw side effect was reported by a consumer or non-health professional from United States. A female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Peridex (drug dosage: NA), which was initiated on
May 01, 2007. Concurrently used drugs:
  • Simvastatin
  • Omeprazole
  • Neurontin
  • Lyrica
  • Lidocaine
  • Procrit /00909301/
  • Glipizide
  • Hydrochlorothiazide
.After starting to take Peridex the consumer reported adverse symptoms, such as: Osteonecrosis Of Jaw, Anxiety, Osteolysis, Gout, Haematochezia, Pulmonary Embolism, Type 2 Diabetes Mellitus, Osteoporosis, Spinal OsteoarthritisThese side effects may potentially be related to Peridex.
Peridex Side Effect Report#7712890-5
Ischaemia, Anxiety, Bone Loss, Influenza, Nodule, Spinal Osteoarthritis, Gastrointestinal Mucosal Disorder, Life Expectancy Shortened, Anhedonia
This is a report of a female patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Peridex (dosage: NA, start time:
Feb 18, 2005), combined with:
  • Simavastatin (Unk)
  • Macrobid (100 Mg, Unk)
  • Tannic Acid (Unk)
  • Chlorhexidine Gluconate (Unk)
  • Diphenhydramine Hcl (50 Mg, Unk)
  • Tretinoin (Unk)
  • Bactrim
  • Zen
and developed a serious reaction and side effect(s): Ischaemia, Anxiety, Bone Loss, Influenza, Nodule, Spinal Osteoarthritis, Gastrointestinal Mucosal Disorder, Life Expectancy Shortened, Anhedonia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex treatment in female patients, resulting in Ischaemia side effect.
Peridex Side Effect Report#7655082-0
Activities Of Daily Living Impaired, Haemorrhage, Asthenia
This report suggests a potential Peridex Activities Of Daily Living Impaired side effect(s) that can have serious consequences. A 92-year-old female patient (weight: NA) from Canada was diagnosed with the following symptoms/conditions: surgery and used Peridex (dosage: NA) starting
Oct 01, 2008. After starting Peridex the patient began experiencing various side effects, including: Activities Of Daily Living Impaired, Haemorrhage, AstheniaAdditional drugs used concurrently: NA. Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Activities Of Daily Living Impaired, may still occur.
Peridex Side Effect Report#7632898-8
Osteonecrosis Of Jaw, Paraesthesia, Pain, Nephrolithiasis, Panic Attack, Infection, Type 2 Diabetes Mellitus, Deep Vein Thrombosis, Anxiety
This Osteonecrosis Of Jaw problem was reported by a consumer or non-health professional from United States. A 70-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
May 01, 2007 this consumer started treatment with Peridex (dosage: NA). The following drugs were being taken at the same time:
  • Coumadin
  • Simvastatin
  • Zometa (4 Mg, Qmo)
  • Clonazepam
  • Revlimid
  • Hydrochlorothiazide
  • Metoprolol Tartrate
  • Glipizide
When using Peridex, the patient experienced the following unwanted symptoms/side effects: Osteonecrosis Of Jaw, Paraesthesia, Pain, Nephrolithiasis, Panic Attack, Infection, Type 2 Diabetes Mellitus, Deep Vein Thrombosis, AnxietyAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Osteonecrosis Of Jaw, may become evident only after a product is in use by the general population.
Peridex Side Effect Report#7564444-1
Gingival Erythema, Pain, Decreased Interest, Osteolysis, Spinal Disorder, Metastases To Spine, Osteoarthritis, Bone Disorder, Gingival Infection
This Gingival Erythema side effect was reported by a consumer or non-health professional from United States. A female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Peridex (drug dosage: NA), which was initiated on
Oct 22, 2004. Concurrently used drugs:
  • Diovan (80 Mg, Qd)
  • Capecitabine
  • Amoxicillin (500 Mg, Tid)
  • Amoxicillin (500 Mg, Tid)
  • Amoxicillin (500 Mg, Tid)
  • Levaquin
  • Oxycodone Hcl
  • Neupogen
.After starting to take Peridex the consumer reported adverse symptoms, such as: Gingival Erythema, Pain, Decreased Interest, Osteolysis, Spinal Disorder, Metastases To Spine, Osteoarthritis, Bone Disorder, Gingival InfectionThese side effects may potentially be related to Peridex.
Peridex Side Effect Report#7456578-7
Renal Papillary Necrosis, Infection, Vomiting, Urinary Retention, Constipation, Dehydration, Abdominal Pain, Weight Decreased, Haematuria
This is a report of a male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Peridex (dosage: NA, start time:
Apr 20, 2006), combined with:
  • Lemon (Unk)
  • Bisacodyl
  • Exjade (1875 Mg, Daily)
  • Blood Transfusion, Auxiliary Products
  • Keppra (8 Ml, Bid)
  • Folic Acid (1 Mg, Daily)
  • Zantac (10 Ml, Bid)
  • Drisdol (5 Ml, Every 3 Months)
and developed a serious reaction and side effect(s): Renal Papillary Necrosis, Infection, Vomiting, Urinary Retention, Constipation, Dehydration, Abdominal Pain, Weight Decreased, Haematuria after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex treatment in male patients, resulting in Renal Papillary Necrosis side effect. The patient was hospitalized.
Peridex Side Effect Report#7426132-1
Cellulitis, Discomfort, Gingival Bleeding, Oropharyngeal Pain, Myalgia, Feeling Jittery, Dyspnoea, Decreased Appetite, Gingival Hyperplasia
This report suggests a potential Peridex Cellulitis side effect(s) that can have serious consequences. A female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: NA and used Peridex (dosage: NA) starting
Feb 18, 2005. After starting Peridex the patient began experiencing various side effects, including: Cellulitis, Discomfort, Gingival Bleeding, Oropharyngeal Pain, Myalgia, Feeling Jittery, Dyspnoea, Decreased Appetite, Gingival HyperplasiaAdditional drugs used concurrently:
  • Tamoxifen
  • Simvastatin (20 , Daily)
  • Evoxac (30mg)
  • Tobradex (Unk)
  • Pravachol (20 Mg)
  • Macrobid (100 Mg)
  • Meclizine (12.5 Mg)
  • Chlorhexidine Gluconate (Unk)
Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Cellulitis, may still occur.
Peridex Side Effect Report#7397587-6
Tooth Discolouration
This Tooth Discolouration problem was reported by a consumer or non-health professional from United States. A 56-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: dental operation. On
Mar 23, 2011 this consumer started treatment with Peridex (dosage: 1 Tbsp 3x Daily Top). The following drugs were being taken at the same time: NA. When using Peridex, the patient experienced the following unwanted symptoms/side effects: Tooth DiscolourationAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Tooth Discolouration, may become evident only after a product is in use by the general population.
Peridex Side Effect Report#7373233-2
Injury, Osteomyelitis, Fistula, Gingival Hyperplasia, Malaise, Laryngeal Oedema, Dizziness, Hiatus Hernia, Periodontal Disease
This Injury side effect was reported by a health professional from United States. A female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Peridex (drug dosage: NA), which was initiated on
Mar 22, 2004. Concurrently used drugs:
  • Simvastatin (20 , Daily)
  • Fosamax (Unk)
  • Levaquin (500 Mg)
  • Alprazolam (0.25 Mg)
  • Tretinoin (Unk)
  • Faslodex
  • Propranolol Hydrochloride
  • Citalopram Hydrobromide
.After starting to take Peridex the consumer reported adverse symptoms, such as: Injury, Osteomyelitis, Fistula, Gingival Hyperplasia, Malaise, Laryngeal Oedema, Dizziness, Hiatus Hernia, Periodontal DiseaseThese side effects may potentially be related to Peridex.
Peridex Side Effect Report#7370076-0
Pulmonary Embolism, Altered State Of Consciousness, Haemorrhoids, Prostate Cancer, Depression, Hypophagia, Prostatic Specific Antigen Increased, Atelectasis, Stress
This is a report of a male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Peridex (dosage: Unk, start time:
Jan 07, 2008), combined with:
  • Hydrocort
  • Apap Tab
  • Dolasetron
  • Relafen (750 Mg Every 12 Hours)
  • Pantoprazole
  • Loperamide
  • Acyclovir (200 Mg, Unk)
  • Oramorph Sr (Unk)
and developed a serious reaction and side effect(s): Pulmonary Embolism, Altered State Of Consciousness, Haemorrhoids, Prostate Cancer, Depression, Hypophagia, Prostatic Specific Antigen Increased, Atelectasis, Stress after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex treatment in male patients, resulting in Pulmonary Embolism side effect.
Peridex Side Effect Report#7311577-0
Diarrhoea, Ageusia, Abdominal Discomfort, Muscular Weakness, Headache, Nausea, Dizziness, Somnolence
This report suggests a potential Peridex Diarrhoea side effect(s) that can have serious consequences. A male patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: gingivitis and used Peridex (dosage: 15ml Once Daily Dental) starting
Feb 11, 2011. After starting Peridex the patient began experiencing various side effects, including: Diarrhoea, Ageusia, Abdominal Discomfort, Muscular Weakness, Headache, Nausea, Dizziness, SomnolenceAdditional drugs used concurrently: NA. Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Diarrhoea, may still occur.
Peridex Side Effect Report#6785217-3
Sensitivity Of Teeth, Tooth Deposit
This Sensitivity Of Teeth problem was reported by a consumer or non-health professional from United States. A 67-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: periodontal disease. On
Apr 20, 2010 this consumer started treatment with Peridex (dosage: Capfull -1-2 Ml- Twice Per Day Po). The following drugs were being taken at the same time: NA. When using Peridex, the patient experienced the following unwanted symptoms/side effects: Sensitivity Of Teeth, Tooth DepositAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Sensitivity Of Teeth, may become evident only after a product is in use by the general population.
Peridex Side Effect Report#5856740-0
Blood Pressure Increased
This Blood Pressure Increased side effect was reported by a consumer or non-health professional from United States. A 73-year-old female patient (weight:NA) experienced the following symptoms/conditions: periodontal disease.The patient was prescribed Peridex (drug dosage: Applies Topically To Two Teeth One Time Po), which was initiated on
Aug 05, 2008. Concurrently used drugs: NA..After starting to take Peridex the consumer reported adverse symptoms, such as: Blood Pressure IncreasedThese side effects may potentially be related to Peridex.
Peridex Side Effect Report#5329424-5
Ageusia
This is a report of a 53-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: gingivitis, who was treated with Peridex (dosage: Oral Rinse Once Daily, start time:
Apr 01, 2003), combined with: NA. and developed a serious reaction and side effect(s): Ageusia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Peridex treatment in male patients, resulting in Ageusia side effect.
Peridex Side Effect Report#5037673-9
Ageusia
This report suggests a potential Peridex Ageusia side effect(s) that can have serious consequences. A 53-year-old male patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: gingival disorder and used Peridex (dosage: .15 Ml Once @ Night Every Day) starting
Mar 01, 2003. After starting Peridex the patient began experiencing various side effects, including: AgeusiaAdditional drugs used concurrently: NA. Although Peridex demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Ageusia, may still occur.


The appearance of Peridex on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Peridex reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Peridex Safety Alerts, Active Ingredients, Usage Information

    NDC48878-0620
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NamePeridex
    Namechlorhexidine gluconate
    Dosage FormRINSE
    RouteORAL
    On market since19860813
    Labeler3M ESPE Dental Products
    Active Ingredient(s)CHLORHEXIDINE GLUCONATE
    Strength(s)1.2
    Unit(s)mg/mL
    Pharma ClassDecreased Cell Wall Integrity [PE]

    Peridex Dosage, Warnings, Usage.

    Side Effects reported to FDA: 22

    Peridex safety alerts: No

    Reported hospitalizations: 2

    Latest Peridex clinical trials