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Peridex Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Fall, Decubitus Ulcer, Pelvic Pain, Pancytopenia, Clostridium Difficile Colitis, Urinary Tract Infection, Renal Failure Acute, Vomiting, Metastases To Bone (8381216-9)
on May 14, 2012 Female from UNITED STATES , weighting 187.4 lb, was treated with Peridex /00133002/. Directly after, patient experienced the unwanted or unexpected Peridex side effects: fall, decubitus ulcer, pelvic pain, pancytopenia, clostridium difficile colitis, urinary tract infection, renal failure acute, vomiting, metastases to bone. Peridex /00133002/ dosage: N/A.
Associated medications used:
  • Neurontin (300 Mg, Tid)
  • Oxycodone Hydrochloride (5 Mg, Prn)
  • Protonix (40 Mg, Qd)
  • Velcade (2.7 Mg, Cyclic)
  • Velcade (2.7 Mg, Cyclic)
  • Antibiotics
  • Decadron (40 Mg, Cyclic)
  • Cytoxan
Patient was hospitalized.

Dehydration, Rash, Vomiting, Speech Disorder, Nausea, Skin Ulcer (8228167-8)
Patient was taking Peridex. Patient felt the following Peridex side effects: dehydration, rash, vomiting, speech disorder, nausea, skin ulcer on Dec 21, 2011 from UNITED STATES Additional patient health information: Male , 61 years of age, . Peridex dosage: 12%.
Multiple prescriptions taken:
  • Robitussin Dm (5-100mg/5ml Syrup 4hrs)
  • Sinequan (10mg/ml Every 4hrs)
  • Ativan (1df = 1tab .5mg Every 4hrs)
  • Compazine (1df= 1tab Of 10mg Every 6hrs)
  • Ativan (1df = 1tab .5mg Every 4hrs)
  • Prevacid (1df = 1cap)
  • Silvadene
  • Tylenol (1df = 1tab 8hr Sustained Release 2/d Prn)
Patient was hospitalized.

Swelling Face, Hypertension, Liver Disorder, Haemoptysis, Osteoarthritis, Osteonecrosis Of Jaw, Ilium Fracture, Haematemesis, Osteoporosis (8198324-8)
Adverse event was reported on Mar 01, 2012 by a Female taking Peridex (Dosage: N/A) . Location: UNITED STATES , weighting 138.0 lb, After Peridex was administered, patient encountered several Peridex side effects: swelling face, hypertension, liver disorder, haemoptysis, osteoarthritis, osteonecrosis of jaw, ilium fracture, haematemesis, osteoporosis.
Multiple concurrent drugs taken:
  • Aspirin
  • Simvastatin (20 Mg, Unk)
  • Metformin Hcl (500 Mg, Unk)
  • Multi-vitamins
  • Femara (2.5 Mg, Unk)
  • Zocor
  • Amaryl (2 Mg, Unk)
  • Anticoagulants


Ageusia (8181625-7)
on Mar 01, 2012 Female from UNITED STATES , 81 years of age, weighting 120.0 lb, was diagnosed with
  • gingivitis
and was treated with Peridex. Directly after, patient experienced the unwanted or unexpected Peridex side effects: ageusia. Peridex dosage: N/A.


Osteonecrosis Of Jaw, Anxiety, Osteolysis, Gout, Haematochezia, Pulmonary Embolism, Type 2 Diabetes Mellitus, Osteoporosis, Spinal Osteoarthritis (7917882-9)
on Nov 09, 2011 Female from UNITED STATES , weighting 184.0 lb, was treated with Peridex. Patient felt the following Peridex side effects: osteonecrosis of jaw, anxiety, osteolysis, gout, haematochezia, pulmonary embolism, type 2 diabetes mellitus, osteoporosis, spinal osteoarthritis. Peridex dosage: N/A.
Multiple prescriptions taken:
  • Simvastatin
  • Omeprazole
  • Neurontin
  • Lyrica
  • Lidocaine
  • Procrit /00909301/
  • Glipizide
  • Hydrochlorothiazide


Ischaemia, Anxiety, Bone Loss, Influenza, Nodule, Spinal Osteoarthritis, Gastrointestinal Mucosal Disorder, Life Expectancy Shortened, Anhedonia (7712890-5)
Patient was taking Peridex. After Peridex was administered, patient encountered several Peridex side effects: ischaemia, anxiety, bone loss, influenza, nodule, spinal osteoarthritis, gastrointestinal mucosal disorder, life expectancy shortened, anhedonia on Aug 17, 2011 from UNITED STATES Additional patient health information: Female , weighting 99.98 lb, . Peridex dosage: N/A.
Multiple concurrent drugs taken:
  • Simavastatin (Unk)
  • Macrobid (100 Mg, Unk)
  • Tannic Acid (Unk)
  • Chlorhexidine Gluconate (Unk)
  • Diphenhydramine Hcl (50 Mg, Unk)
  • Tretinoin (Unk)
  • Bactrim
  • Zen


Activities Of Daily Living Impaired, Haemorrhage, Asthenia (7655082-0)
Adverse event was reported on Jul 19, 2011 by a Female taking Peridex (Dosage: N/A) was diagnosed with
  • surgery
and. Location: CANADA , 92 years of age, Directly after, patient experienced the unwanted or unexpected Peridex side effects: activities of daily living impaired, haemorrhage, asthenia.

Osteonecrosis Of Jaw, Paraesthesia, Pain, Nephrolithiasis, Panic Attack, Infection, Type 2 Diabetes Mellitus, Deep Vein Thrombosis, Anxiety (7632898-8)
on Jul 13, 2011 Female from UNITED STATES , 70 years of age, was treated with Peridex. Patient felt the following Peridex side effects: osteonecrosis of jaw, paraesthesia, pain, nephrolithiasis, panic attack, infection, type 2 diabetes mellitus, deep vein thrombosis, anxiety. Peridex dosage: N/A.
Multiple prescriptions taken:
  • Coumadin
  • Simvastatin
  • Zometa (4 Mg, Qmo)
  • Clonazepam
  • Revlimid
  • Hydrochlorothiazide
  • Metoprolol Tartrate
  • Glipizide


Gingival Erythema, Pain, Decreased Interest, Osteolysis, Spinal Disorder, Metastases To Spine, Osteoarthritis, Bone Disorder, Gingival Infection (7564444-1)
on Jun 14, 2011 Female from UNITED STATES , weighting 123.9 lb, was treated with Peridex. After Peridex was administered, patient encountered several Peridex side effects: gingival erythema, pain, decreased interest, osteolysis, spinal disorder, metastases to spine, osteoarthritis, bone disorder, gingival infection. Peridex dosage: N/A.
Multiple concurrent drugs taken:
  • Diovan (80 Mg, Qd)
  • Capecitabine
  • Amoxicillin (500 Mg, Tid)
  • Amoxicillin (500 Mg, Tid)
  • Amoxicillin (500 Mg, Tid)
  • Levaquin
  • Oxycodone Hcl
  • Neupogen


Renal Papillary Necrosis, Infection, Vomiting, Urinary Retention, Constipation, Dehydration, Abdominal Pain, Weight Decreased, Haematuria (7456578-7)
Patient was taking Peridex. Directly after, patient experienced the unwanted or unexpected Peridex side effects: renal papillary necrosis, infection, vomiting, urinary retention, constipation, dehydration, abdominal pain, weight decreased, haematuria on Apr 20, 2011 from UNITED STATES Additional patient health information: Male , weighting 109.7 lb, . Peridex dosage: N/A.
Associated medications used:
  • Lemon (Unk)
  • Bisacodyl
  • Exjade (1875 Mg, Daily)
  • Blood Transfusion, Auxiliary Products
  • Keppra (8 Ml, Bid)
  • Folic Acid (1 Mg, Daily)
  • Zantac (10 Ml, Bid)
  • Drisdol (5 Ml, Every 3 Months)
Patient was hospitalized.

Cellulitis, Discomfort, Gingival Bleeding, Oropharyngeal Pain, Myalgia, Feeling Jittery, Dyspnoea, Decreased Appetite, Gingival Hyperplasia (7426132-1)
Adverse event was reported on Apr 08, 2011 by a Female taking Peridex (Dosage: N/A) . Location: UNITED STATES , weighting 99.98 lb, Patient felt the following Peridex side effects: cellulitis, discomfort, gingival bleeding, oropharyngeal pain, myalgia, feeling jittery, dyspnoea, decreased appetite, gingival hyperplasia.
Multiple prescriptions taken:
  • Tamoxifen
  • Simvastatin (20 , Daily)
  • Evoxac (30mg)
  • Tobradex (Unk)
  • Pravachol (20 Mg)
  • Macrobid (100 Mg)
  • Meclizine (12.5 Mg)
  • Chlorhexidine Gluconate (Unk)


Tooth Discolouration (7397587-6)
on Apr 01, 2011 Female from UNITED STATES , 56 years of age, weighting 120.0 lb, was diagnosed with
  • dental operation
and was treated with Peridex. After Peridex was administered, patient encountered several Peridex side effects: tooth discolouration. Peridex dosage: 1 Tbsp 3x Daily Top.

Injury, Osteomyelitis, Fistula, Gingival Hyperplasia, Malaise, Laryngeal Oedema, Dizziness, Hiatus Hernia, Periodontal Disease (7373233-2)
on Mar 11, 2011 Female from UNITED STATES , weighting 99.98 lb, was treated with Peridex. Directly after, patient experienced the unwanted or unexpected Peridex side effects: injury, osteomyelitis, fistula, gingival hyperplasia, malaise, laryngeal oedema, dizziness, hiatus hernia, periodontal disease. Peridex dosage: N/A.
Associated medications used:
  • Simvastatin (20 , Daily)
  • Fosamax (Unk)
  • Levaquin (500 Mg)
  • Alprazolam (0.25 Mg)
  • Tretinoin (Unk)
  • Faslodex
  • Propranolol Hydrochloride
  • Citalopram Hydrobromide


Pulmonary Embolism, Altered State Of Consciousness, Haemorrhoids, Prostate Cancer, Depression, Hypophagia, Prostatic Specific Antigen Increased, Atelectasis, Stress (7370076-0)
Patient was taking Peridex. Patient felt the following Peridex side effects: pulmonary embolism, altered state of consciousness, haemorrhoids, prostate cancer, depression, hypophagia, prostatic specific antigen increased, atelectasis, stress on Mar 09, 2011 from UNITED STATES Additional patient health information: Male , weighting 405.7 lb, . Peridex dosage: Unk.
Multiple prescriptions taken:
  • Hydrocort
  • Apap Tab
  • Dolasetron
  • Relafen (750 Mg Every 12 Hours)
  • Pantoprazole
  • Loperamide
  • Acyclovir (200 Mg, Unk)
  • Oramorph Sr (Unk)


Diarrhoea, Ageusia, Abdominal Discomfort, Muscular Weakness, Headache, Nausea, Dizziness, Somnolence (7311577-0)
Adverse event was reported on Feb 16, 2011 by a Male taking Peridex (Dosage: 15ml Once Daily Dental) was diagnosed with
  • gingivitis
and. Location: UNITED STATES , weighting 162.0 lb, After Peridex was administered, patient encountered several Peridex side effects: diarrhoea, ageusia, abdominal discomfort, muscular weakness, headache, nausea, dizziness, somnolence.

Sensitivity Of Teeth, Tooth Deposit (6785217-3)
on Jun 22, 2010 Male from UNITED STATES , 67 years of age, weighting 150.0 lb, was diagnosed with
  • periodontal disease
and was treated with Peridex. Directly after, patient experienced the unwanted or unexpected Peridex side effects: sensitivity of teeth, tooth deposit. Peridex dosage: Capfull -1-2 Ml- Twice Per Day Po.

Blood Pressure Increased (5856740-0)
on Aug 22, 2008 Female from UNITED STATES , 73 years of age, weighting 170.0 lb, was diagnosed with
  • periodontal disease
and was treated with Peridex. Patient felt the following Peridex side effects: blood pressure increased. Peridex dosage: Applies Topically To Two Teeth One Time Po.

Ageusia (5329424-5)
Patient was taking Peridex. After Peridex was administered, patient encountered several Peridex side effects: ageusia on May 25, 2006 from UNITED STATES Additional patient health information: Male , 53 years of age, was diagnosed with
  • gingivitis
and. Peridex dosage: Oral Rinse Once Daily.

Ageusia (5037673-9)
Adverse event was reported on Jun 26, 2006 by a Male taking Peridex (Dosage: .15 Ml Once @ Night Every Day) was diagnosed with
  • gingival disorder
and. Location: UNITED STATES , 53 years of age, weighting 150.0 lb, Directly after, patient experienced the unwanted or unexpected Peridex side effects: ageusia.

Peridex Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Peridex Information

Alternative PERIDEX Names:CHLORHEXI

Active Ingredient: CHLORHEXI

Peridex Dosage, Warnings, Usage.

Side Effects reported to FDA: 19. View Peridex Adverse Reports

Peridex safety alerts: No

Reported hospitalizations: 2

Managing Your Medicines

Tips for Taking Medicines Properly

Before Taking Peridex

Find Out How to Take Peridex

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