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Posaconazole Safety Reports
Total Posaconazole reports: 49.Posaconazole FDA safety alerts: No.
Reported deaths: 20 Reported hospitalizations: 36.
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Reported Posaconazole Side Effects: disease progression, nausea, condition aggravated, bronchitis, blood alkaline phosphatase increased, cardiac failure congestive, respiratory failure, hypercapnia, haemoglobin decreased, haematocrit decreased, pneumonia fungal.
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Posaconazole Side Effects Report #5208042-3
Physician from MALAYSIA reported POSACONAZOLE problem on Dec 26, 2006. Male patient, 41 years of age, weighting 110.2 lb, was diagnosed with fusarium infection, sepsis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: haematocrit decreased, haemoglobin decreased, haemorrhoids, platelet count decreased, red blood cell count decreased, upper gastrointestinal haemorrhage. POSACONAZOLE dosage: 200 MG, QID; PO. During the same period patient was treated with IMIPENEM, ACYCLOVIR, OMEPRAZOLE, DAFLON, IMMUNE GLOBULIN INTRAVENOUS. Patient was hospitalized. Patient died on 12/23/2006.
Posaconazole Side Effects Report #5208057-5
POSACONAZOLE problem was reported by a Physician from GERMANY on Dec 28, 2006. Male patient, 75 years of age, was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, cardiac failure. POSACONAZOLE dosage: 300 MG, QD; IV. During the same period patient was treated with METOPROLOL SUCCINATE, POTASSIUM CHLORIDE, RAMIPRIL. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5209733-0
Physician from BELGIUM reported POSACONAZOLE problem on Dec 27, 2006. Male patient, 48 years of age, weighting 158.7 lb, was diagnosed with prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: haematocrit decreased, haemoglobin decreased, multi-organ failure, pneumonia. POSACONAZOLE dosage: 400 MG; IV; 300 MG; IV; 400 MG; IV-SEE IMAGE. Patient was hospitalized. Patient died on 12/24/2006.
Posaconazole Side Effects Report #5215233-4
POSACONAZOLE problem was reported by a Physician from BELGIUM on Jan 08, 2007. Female patient, 30 years of age, weighting 110.2 lb, was diagnosed with fungal infection, pleuritic pain and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, bronchitis, disease progression, hypercapnia, lung neoplasm, nausea, pleuritic pain, pneumonia, respiratory failure. POSACONAZOLE dosage: SEE IMGAE. During the same period patient was treated with MORPHINE, AMBISOME, NEORAL. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5220124-9
Pharmacist from UNITED STATES reported POSACONAZOLE problem on Jan 25, 2007. Female patient, 29 years of age, weighting 260.1 lb, was diagnosed with fungal skin infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: oedema peripheral. POSACONAZOLE dosage: 200MG QID PO. Patient recovered.
Posaconazole Side Effects Report #5228823-X
POSACONAZOLE problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 12, 2006. Female patient, 58 years of age, was treated with POSACONAZOLE. POSACONAZOLE dosage: unknown. Patient died on 11/24/2004.
Posaconazole Side Effects Report #5237881-8
Consumer or non-health professional from UNITED STATES reported POSACONAZOLE problem on Jan 31, 2007. Female patient, 58 years of age, was treated with POSACONAZOLE. POSACONAZOLE dosage: unknown. Patient died on 11/24/2004.
Posaconazole Side Effects Report #5237950-2
POSACONAZOLE problem was reported by a Physician from MALAYSIA on Jan 30, 2007. Male patient, 41 years of age, weighting 110.2 lb, was diagnosed with fungal sepsis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: haematocrit decreased, haemoglobin decreased, monocyte percentage increased, neutrophil percentage decreased, red blood cell count decreased, upper gastrointestinal haemorrhage. POSACONAZOLE dosage: 200 MG; QID; PO. During the same period patient was treated with IMIPENEM, ACYCLOVIR, OMEPRAZOLE, DAFLON, IMMUNE GLOBULIN INTRAVENOUS. Patient was hospitalized. Patient died on 12/23/2006.
Posaconazole Side Effects Report #5243841-3
Physician from BELGIUM reported POSACONAZOLE problem on Feb 01, 2007. Female patient, 30 years of age, weighting 110.2 lb, was diagnosed with fungal infection, pleuritic pain and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, bronchitis, disease progression, hypercapnia, lung neoplasm, nausea, pleuritic pain, pneumonia, pulmonary mycosis. POSACONAZOLE dosage: unknown. During the same period patient was treated with MORPHINE, AMBISON, NEORAL. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5251992-2
POSACONAZOLE problem was reported by a Physician from CANADA on Feb 12, 2007. Male patient, 20 years of age, weighting 152.1 lb, was diagnosed with prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, haemoglobin decreased, haemolytic uraemic syndrome, intra-abdominal haemorrhage, multi-organ failure, thrombotic thrombocytopenic purpura. POSACONAZOLE dosage: 200 MG; TID; PO. During the same period patient was treated with FOLIC ACID, PENICILLIN V POTASSIUM, PREDNISONE, BENADRYL, HYDROCORTISONE, IMURAN, AMPHOTERICIN B. Patient was hospitalized. Patient died on 11/11/1999.
Posaconazole Side Effects Report #5252063-1
Physician from GERMANY reported POSACONAZOLE problem on Feb 09, 2007. Male patient, 75 years of age, was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, cardiac failure. POSACONAZOLE dosage: 300 MG QD IV. During the same period patient was treated with METOPROLOL SUCCINATE, POTASSIUM CHLORIDE, RAMIPRIL, BELOK ZOK MITE. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5254741-7
POSACONAZOLE problem was reported by a Pharmacist from UNITED STATES on Feb 12, 2007. Male patient, 51 years of age, was diagnosed with zygomycosis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: stem cell transplant. POSACONAZOLE dosage: unknown. During the same period patient was treated with AMPHOTERICIN B. Patient died.
Posaconazole Side Effects Report #5270184-4
Physician from CANADA reported POSACONAZOLE problem on Mar 01, 2007. Female patient was treated with POSACONAZOLE. POSACONAZOLE dosage: unknown. Patient died on 02/27/2007.
Posaconazole Side Effects Report #5271124-4
POSACONAZOLE problem was reported by a Physician from SWITZERLAND on Mar 02, 2007. Male patient, 48 years of age, weighting 216.1 lb, was diagnosed with sinusitis fungal, pain, herpes virus infection, prophylaxis, pneumonia, sedation and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: arteriosclerosis, arteriosclerosis coronary artery, bradycardia, bradypnoea, brain stem syndrome, cardiovascular disorder, cerebral disorder, coma, condition aggravated. POSACONAZOLE dosage: 400 MG; BID; PO. During the same period patient was treated with MORPHINE, ACYCLOVIR, TAXOBACTAM, PROPOFOL, ABELCET, VORICONAZOLE, DIFLUCAN. Patient was hospitalized. Patient died on 08/07/2005.
Posaconazole Side Effects Report #5282611-7
Physician from UNITED STATES reported POSACONAZOLE problem on Mar 13, 2007. Female patient, 67 years of age, weighting 143.0 lb, was diagnosed with systemic mycosis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: atelectasis, blood albumin decreased, blood potassium decreased, cardiac failure congestive, chronic obstructive pulmonary disease, condition aggravated, fibrin d dimer increased, haematocrit decreased, haemoglobin decreased. POSACONAZOLE dosage: 400 MG; BID. During the same period patient was treated with CIPROFLOXACIN, ATENOLOL, AVANDIA, ASPIRIN, ALBUTEROL SULPHATE, FISH OIL, GLYBURIDE. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5285017-X
POSACONAZOLE problem was reported by a Physician from SWITZERLAND on Mar 20, 2007. Male patient, 48 years of age, weighting 216.1 lb, was diagnosed with fungal infection, pain, antiviral prophylaxis, pneumonia, sedation and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: bradycardia, bradypnoea, cerebral disorder, coma, condition aggravated, hepatic enzyme increased, hypotension, liver disorder, respiratory failure. POSACONAZOLE dosage: 400 MG;BID;PO. During the same period patient was treated with MORPHINE, ACYCLOVIR, TAXOBACTAM, PROPOFOL, ABELCET, VORICONAZOLE, DIFLUCAN. Patient was hospitalized. Patient died on 08/07/2005.
Posaconazole Side Effects Report #5291416-2
Physician from CANADA reported POSACONAZOLE problem on Mar 19, 2007. Male patient, weighting 131.8 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest, lung infection, pulmonary haemorrhage, zygomycosis. POSACONAZOLE dosage: 400 MG;BID;PO. During the same period patient was treated with CODEINE, ATARAX, LORAZEPAM, OLANZAPINE, BENADRYL, LINEZOLID, CIPROFLOXACIN. Patient was hospitalized. Patient died on 02/27/2007.
Posaconazole Side Effects Report #5314766-X
POSACONAZOLE problem was reported by a Physician from GERMANY on Apr 11, 2007. Male patient, 75 years of age, was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, cardiac failure. POSACONAZOLE dosage: 300 MG; QD; IV. During the same period patient was treated with METOPROLOL SUCCINATE, POTASSIUM CHLORIDE, RAMIPRIL, BELOK ZOK MITE. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5316289-0
Physician from UNITED STATES reported POSACONAZOLE problem on Apr 16, 2007. Female patient, 61 years of age, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia recurrent, dehydration, nausea, pyrexia, vomiting. POSACONAZOLE dosage: 400 MG; BID; PO. Patient was hospitalized. Patient died on 07/03/2006.
Posaconazole Side Effects Report #5321088-X
POSACONAZOLE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 24, 2007. Female patient, 17 years of age, weighting 185.2 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: electrocardiogram qt corrected interval prolonged, palpitations, tachyarrhythmia. POSACONAZOLE dosage: 400 MG; BID; PO. During the same period patient was treated with EPINEPHRINE. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5323102-4
Physician from GERMANY reported POSACONAZOLE problem on Apr 23, 2007. Male patient, 61 years of age, weighting 174.2 lb, was diagnosed with fungal infection, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in intestine, acute graft versus host disease in skin, cholelithiasis, cholestasis, constipation, convulsion, cystitis, cytomegalovirus infection, dehydration. POSACONAZOLE dosage: 200 MG; QID; PO. During the same period patient was treated with PROGRAF, ACYCLOVIR, SANDIMMUNE, DECORTIN, CELLCEPT, GANCICLOVIR, BELOC ZOC COMP. Patient was hospitalized. Patient died on 05/21/2006.
Posaconazole Side Effects Report #5325755-3
POSACONAZOLE problem was reported by a Physician from UNITED STATES on May 01, 2007. Male patient, 43 years of age, weighting 156.0 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, atrioventricular block first degree, blood culture positive, blood pressure decreased, cardiac failure congestive, diphtheria, fluid overload, infected skin ulcer, left atrial dilatation. POSACONAZOLE dosage: 400 MG; BID; PO. During the same period patient was treated with REGLAN, SYNTHROID, MEGACE, LISINOPRIL, PROTONIX, PREDNISONE, PHOS LO, LANTUS. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5325810-8
Physician from GERMANY reported POSACONAZOLE problem on Apr 30, 2007. Male patient, 71 years of age, weighting 176.4 lb, was diagnosed with antifungal prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: bacterial sepsis, pyrexia. POSACONAZOLE dosage: unknown. During the same period patient was treated with CYTARABINE, DAUNORUBICIN, PRIMAXIN, VANCOMYCIN, TAZOBAC, GENTAMICIN. Patient was hospitalized. Patient died on 04/28/2007.
Posaconazole Side Effects Report #5326536-7
POSACONAZOLE problem was reported by a Physician from UNITED STATES on May 04, 2007. Male patient, 20 years of age, weighting 123.5 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, cholelithiasis, dehydration, hyperbilirubinaemia, hypoalbuminaemia, hypotension, oral intake reduced. POSACONAZOLE dosage: 400 MG; BID; PO. During the same period patient was treated with ZENERGAN, DEPAKENE, MEGACE, FOLIC ACID, PREVACID. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5331085-6
Physician from GERMANY reported POSACONAZOLE problem on May 08, 2007. Male patient, 71 years of age, weighting 176.4 lb, was diagnosed with antifungal prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: bacterial sepsis. POSACONAZOLE dosage: unknown. During the same period patient was treated with CYTARABINE, DAUNORUBICIN, PRIMAXIN, VANCOMYCIN, TAZOBAC, GENTAMICIN. Patient was hospitalized. Patient died on 04/28/2007.
Posaconazole Side Effects Report #5331990-0
POSACONAZOLE problem was reported by a Physician from UNITED STATES on Feb 12, 2007. Female patient was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: anaemia haemolytic autoimmune. POSACONAZOLE dosage: 200 MG; Q6H; PO. During the same period patient was treated with VORICONAZOLE, MICAFUNGIN, AMBISOME, CASPOFUNGIN, BUDESONIDE. Patient recovered.
Posaconazole Side Effects Report #5355219-2
Consumer or non-health professional from UNITED STATES reported POSACONAZOLE problem on Apr 25, 2007. Male patient, weighting 14.55 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased. POSACONAZOLE dosage: unknown. During the same period patient was treated with AMBISOME, ETOPOSIDE, DEXAMETHASONE, CYCLOSPORINE. Patient recovered.
Posaconazole Side Effects Report #5353175-4
POSACONAZOLE problem was reported by a Health Professional from UNITED STATES on June 05, 2007. Female patient, 61 years of age, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia recurrent, cardio-respiratory arrest, dehydration, nausea, pyrexia, vomiting. POSACONAZOLE dosage: 400 MG;BID;PO. Patient was hospitalized. Patient died on 07/03/2006.
Posaconazole Side Effects Report #5100061-0
Physician from UNITED STATES reported POSACONAZOLE problem on Aug 23, 2006. Female patient, 56 years of age, weighting 110.2 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: anorexia, condition aggravated, dilatation atrial, disease progression, fungal infection, hyperkalaemia, hypoaesthesia, pain, sinus congestion. POSACONAZOLE dosage: 400 MG; BID; PO. During the same period patient was treated with NORVASC, BICARBONATE, EPOGEN, DUPHALAC, PREVACID, SYNTHROID, ZOLOFT, PREDNISONE. Patient recovered.
Posaconazole Side Effects Report #5108064-7
POSACONAZOLE problem was reported by a Health Professional from UNITED STATES on Sept 01, 2006. Female patient, 17 years of age, weighting 185.2 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: electrocardiogram qt corrected interval prolonged, palpitations, tachyarrhythmia. POSACONAZOLE dosage: 400 MG, BID; PO. During the same period patient was treated with EPINEPHRINE. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5119287-5
Physician from UNITED STATES reported POSACONAZOLE problem on Sept 13, 2006. Female patient, 66 years of age, weighting 173.0 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: blood albumin decreased, blood creatinine increased, blood potassium decreased, bradycardia, brain natriuretic peptide increased, cardiac failure congestive, condition aggravated, electrocardiogram abnormal, electrocardiogram qt corrected interval prolonged. POSACONAZOLE dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, ATENOLOL, AVANDIA, ASPIRIN, ALBUTEROL SULPHATE, FISH OIL, GLYBURIDE. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5120895-6
POSACONAZOLE problem was reported by a Physician from PORTUGAL on Sept 15, 2006. Male patient was diagnosed with aspergillosis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: coma, malnutrition. POSACONAZOLE dosage: 200 MG; QD; NGT. During the same period patient was treated with LIPOSSOMAL ANPHOTERICINE B, VORICONAZOLE, CASPOPHUNGINE. Patient recovered.
Posaconazole Side Effects Report #5126359-8
Physician from UNITED STATES reported POSACONAZOLE problem on Sept 26, 2006. Female patient, 66 years of age, weighting 173.0 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: aspiration pleural cavity abnormal, blood albumin decreased, blood creatine increased, blood potassium decreased, cardiac failure congestive, condition aggravated, dyspnoea, electrocardiogram qt corrected interval prolonged, electrolyte imbalance. POSACONAZOLE dosage: 400 MG;BID. During the same period patient was treated with CIPROFLOXACIN, ATENOLOL, AVANDIA, ASPIRIN, ALBUTEROL SULATE, FISH OIL, GLYBURIDE, SYNTHROID. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5136019-5
POSACONAZOLE problem was reported by a Consumer or non-health professional from GERMANY on Sept 21, 2006. Female patient, child 10 years of age, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: adenovirus infection, multi-organ failure, stem cell transplant, transplant rejection. POSACONAZOLE dosage: 200 MG; QID; PO. During the same period patient was treated with METHYLPREDNISOLONE, CYCLOSPORINE, ATGAM, FLUCONAZOLE, TRIMETHOPRIM, AMPHOTERICIN B, VORICONAZOLE, CASPOFUNGIN. Patient was hospitalized. Patient died on 02/01/2005.
Posaconazole Side Effects Report #5139691-9
Physician from FRANCE reported POSACONAZOLE problem on Oct 06, 2006. Female patient, 40 years of age, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: ascites, aspergillosis, blood disorder, blood pressure decreased, bronchitis, coma, culture urine positive, cytolytic hepatitis, disease progression. POSACONAZOLE dosage: 400 MG; BID; PO. During the same period patient was treated with EFFEXOR, VORICONAZOLE, ROCEPHIN, CIFLOX, VITAMIN CAP, RED BLOOD CELLS, PLATELETS, POLARAMINE. Patient was hospitalized. Patient died on 12/22/2002.
Posaconazole Side Effects Report #5141161-9
POSACONAZOLE problem was reported by a Physician from BELGIUM on Oct 06, 2006. Female patient, 30 years of age, weighting 110.2 lb, was diagnosed with fungal infection, pleuritic pain and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, bronchitis, disease progression, hepatic enzyme increased, hypercapnia, lung neoplasm, nausea, pleuritic pain, pneumonia fungal. POSACONAZOLE dosage: unknown. During the same period patient was treated with MORPHINE, AMBISOME, NEORAL. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5147342-2
Physician from UNITED STATES reported POSACONAZOLE problem on Oct 16, 2006. Male patient, 43 years of age, weighting 156.0 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, atrioventricular block first degree, blood pressure decreased, cardiac failure congestive, dilatation atrial, fluid overload, fungal infection, infected skin ulcer, mitral valve incompetence. POSACONAZOLE dosage: 400 MG; BID; PO. During the same period patient was treated with REGLAN, SYNTHROID, MEGACE, LISINOPRIL, PROTONIX, PREDNISONE, PHOSLO, LANTUS. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5148250-3
POSACONAZOLE problem was reported by a Physician from GERMANY on Aug 22, 2006. Female patient, 50 years of age, was diagnosed with neutropenia and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: lung infiltration, respiratory failure. POSACONAZOLE dosage: unknown. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5153632-X
Physician from GERMANY reported POSACONAZOLE problem on Oct 30, 2006. Male patient, 61 years of age, weighting 174.2 lb, was diagnosed with fungal infection, prophylaxis against graft versus host disease, antiviral prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: bacterial sepsis, benign prostatic hyperplasia, blood disorder, cardiac failure, cholelithiasis, cholestasis, condition aggravated, constipation, convulsion. POSACONAZOLE dosage: 200 MG;QID;PO. During the same period patient was treated with PROGRAF, ACYCLOVIR, SANDIMMUNE, DECORTIN, GANCICLOVIR, CELLCEPT, BELOC ZOC COMP. Patient was hospitalized. Patient died on 05/21/2006.
Posaconazole Side Effects Report #5162112-7
POSACONAZOLE problem was reported by a Physician from BELGIUM on Nov 07, 2006. Female patient, 30 years of age, weighting 110.2 lb, was diagnosed with fungal infection, pleuritic pain and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: bacterial infection, blood alkaline phosphatase increased, bronchitis, disease progression, fungal infection, hypercapnia, lung infiltration, nausea, nodule. POSACONAZOLE dosage: unknown. During the same period patient was treated with MORPHINE, AMBISOME, NEORAL. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5165182-5
Physician from BELGIUM reported POSACONAZOLE problem on Nov 20, 2006. Female patient, 30 years of age, weighting 110.2 lb, was diagnosed with fungal infection, pleuritic pain and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, bronchitis, disease progression, hypercapnia, nausea, pleuritic pain, pneumonia, respiratory failure, stenotrophomonas infection. POSACONAZOLE dosage: 200 MG QID PO ; 400 MG BID ; 200 MG QID ; 200 MG BID. During the same period patient was treated with MORPHINE, NEOROL, MEDROL. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5167462-6
POSACONAZOLE problem was reported by a Physician from BELGIUM on Nov 20, 2006. Female patient, 30 years of age, weighting 110.2 lb, was diagnosed with fungal infection, pleuritic pain and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, bronchitis, disease progression, hypercapnia, lung neoplasm, nausea, pneumonia, respiratory failure, stenotrophomonas infection. POSACONAZOLE dosage: unknown. During the same period patient was treated with MORPHINE, AMBISOME, NEORAL, PARENTERAL NUTRITION, MEDROL. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5170150-3
Pharmacist from BELGIUM reported POSACONAZOLE problem on Dec 04, 2006. Male patient, 32 years of age, was diagnosed with fungal skin infection, scedosporium infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: disease progression, fungal skin infection, scedosporium infection, shock. POSACONAZOLE dosage: 800 MG; QD; PO. During the same period patient was treated with SYMBICORT, DURAGESIC, XANAX, MOXON, PERINDOPRIL ERBUMINE, LANTUS, NOVORAPID. Patient died on 09/04/2006.
Posaconazole Side Effects Report #5179512-1
POSACONAZOLE problem was reported by a Physician from GERMANY on Nov 23, 2006. Female patient, 50 years of age, was diagnosed with neutropenia and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in liver, acute graft versus host disease in skin, catheter related infection, haemolytic anaemia, pneumonia, polyneuropathy, renal failure acute, respiratory failure. POSACONAZOLE dosage: unknown. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5182667-6
Physician from UNITED STATES reported POSACONAZOLE problem on Nov 29, 2006. Male patient, 30 years of age, was diagnosed with aspergillosis, acute lymphocytic leukaemia and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: capillary leak syndrome, leukopenia, palmar-plantar erythrodysaesthesia syndrome. POSACONAZOLE dosage: unknown. During the same period patient was treated with CLOFARABINE. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5199526-5
POSACONAZOLE problem was reported by a Physician from BELGIUM on Dec 19, 2006. Male patient, 48 years of age, weighting 158.7 lb, was diagnosed with prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: haematocrit decreased, haemoglobin decreased, pneumonia, respiratory distress. POSACONAZOLE dosage: 300 MG; QD. Patient was hospitalized. Patient recovered.
Posaconazole Side Effects Report #5460963-2
Consumer or non-health professional from UNITED STATES reported POSACONAZOLE problem on Apr 25, 2007. Male patient, weighting 14.55 lb, was diagnosed with fungal infection and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: hepatic enzyme increased. POSACONAZOLE dosage: 60 MG; TID; PO; 30 MG; TID; PO. During the same period patient was treated with AMBISOME, ETOPOSIDE, DEXAMETHASONE, CYCLOSPORINE. Patient recovered.
Posaconazole Side Effects Report #5448644-2
POSACONAZOLE problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 07, 2007. Female patient, 60 years of age, was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: vision blurred. POSACONAZOLE dosage: 200 MG PO TID. During the same period patient was treated with MICAFUNGIN, LEVOTHYROXINE, PREDNISONE, BACTRIM, OMEPRAZOLE, CALCIUM WITH VITAMIN D, DARBEPOETIN. Patient recovered.
Posaconazole Side Effects Report #5449274-9
Physician from GERMANY reported POSACONAZOLE problem on Aug 28, 2007. Male patient, 68 years of age, was diagnosed with antifungal prophylaxis and was treated with POSACONAZOLE. After drug was administered, patient experienced the following problems/side effects: blood culture positive, fungal sepsis, klebsiella infection, pathogen resistance, trichosporon infection. POSACONAZOLE dosage: 200 MG;TID ; 200 MG;QID. During the same period patient was treated with MITOXANTRON, DAUNORUBICIN, THIOGUANINE, CYTARABINE, PIPERACILLIN, TAZOBACTAM. Patient recovered.
Drug Information: Posaconazole
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a607036.html
poe" sa kon' a zoleWhy is this medication prescribed?
Posaconazole is used to prevent serious fungal infections in people with a weakened ability to fight infection. Posaconazole is also used to treat yeast infections of the mouth and throat including yeast infections that could not be treated successfully with other medications. Posaconazole is in a class of antifungals called triazoles. It works by slowing the growth of fungi that cause infection.
How should this medicine be used?
Posaconazole comes as a suspension (liquid) to take by mouth. Each dose should be taken with a full meal or liquid nutritional supplement. When posaconazole is used to prevent fungal infections, it is usually taken three times a day. When posaconazole is used to treat yeast infections of the mouth and throat, it is usually taken once or twice a day. The length of your treatment depends on your general health, the type of infection you have, and how well you respond to this medication. Take posaconazole at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take posaconazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Shake the liquid well before each use to mix the medication evenly.
Posaconazole comes with a dosing spoon to measure your dose. The spoon should be rinsed thoroughly with water after each use and before storing.
Continue to take posaconazole until your doctor tells you that you should stop, even if you feel better. Do not stop taking posaconazole without talking to your doctor. If you stop taking posaconazole too soon, your infection may not be completely treated.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking posaconazole,
- tell your doctor and pharmacist if you are allergic to posaconazole; other antifungal medications such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend); simethicone; any other medications; or any of the ingredients in posaconazole. Ask your pharmacist for a list of the ingredients.
- do not take posaconazole if you are taking any of the following medications: astemizole (Hismanal) (not available in the U.S.); cisapride (Propulsid); ergot-type medications such as bromocriptine (Parlodel), cabergoline (Dostinex), dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Germinal, Hydergine), ergonovine (Ergotrate), ergotamine (Bellergal-S, Cafergot, Ergomar, Wigraine), methylergonovine (Methergine), and pergolide (Permax); halofantrine (Halfan) (not available in the U.S.); pimozide (Orap); quinidine; or terfenadine (Seldane) (not available in the U.S.).
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: benzodiazepines such as alprazolam (Xanax), diazepam (Valium), midazolam (Versed), and triazolam (Halcion); calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), nifedipine (Adalat, Procardia), nisoldipine (Sular), and verapamil (Calan, Isoptin, Verelan); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor), lovastatin (Mevacor), and simvastatin (Zocor); cimetidine (Tagamet); cyclosporine (Gengraf, Neoral, Sandimmune); erythromycin (E.E.S., E-Mycin, Erythrocin), glipizide (Glucotrol); phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); sirolimus (Rapamune); tacrolimus (Prograf); vinblastine; and vincristine. Many other medications may also interact with posaconazole, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you cannot eat a full meal or liquid nutritional supplement and if you have or have ever had an irregular heartbeat; kidney or liver disease; or low levels of calcium, magnesium, or potassium in your blood.Also tell your doctor if you develop severe diarrhea or vomiting at any time during your treatment.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking posaconazole, call your doctor.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Posaconazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- fever
- headache
- chills or shaking
- dizziness
- weakness
- swelling of the hands, feet, ankles, or lower legs
- diarrhea
- vomiting
- stomach pain
- constipation
- heartburn
- weight loss
- rash
- itching
- back or muscle pain
- sores on the lips, mouth, or throat
- difficulty falling asleep or staying asleep
- anxiety
- increased sweating
- nosebleeds
- coughing
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- unusual bruising or bleeding
- extreme tiredness
- lack of energy
- loss of appetite
- nausea
- pain in the upper right part of the stomach
- yellowing of the skin or eyes
- flu-like symptoms
- dark urine
- pale stools
- fast, pounding, or irregular heartbeat
- sudden loss of consciousness
- shortness of breath
- decreased urination
Posaconazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze this medication. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to posaconazole.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. If you still have symptoms of infection after you finish taking posaconazole, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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