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Primperan Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 91 

Febrile Neutropenia, Diarrhoea, Epistaxis, Mucosal Inflammation (8071260-3)
on Jan 13, 2012 Male from SPAIN , 60 years of age, weighting 149.9 lb, was diagnosed with
  • nausea
  • allergy prophylaxis
  • vomiting
  • non-small cell lung cancer
and was treated with Primperan Tab. Directly after, patient experienced the unwanted or unexpected Primperan side effects: febrile neutropenia, diarrhoea, epistaxis, mucosal inflammation. Primperan Tab dosage: Mg, As Needed.
Associated medications used:
  • Dexamethasone (1 Mg, 2x/day)
  • Ondansetron (3 Mg, 3x/day)
  • Carboplatin (714 Mg, Every 3 Weeks)
  • Erlotinib Hydrochloride (150 Mg, 1x/day)
  • Lorazepam (1 G, 3x/day)
  • Paracetamol (1 G, 3x/day)
  • Paclitaxel (360 Mg, Every 3 Weeks)
  • Cp-751,871 (1360 Mg, Every 3 Weeks)
Patient was hospitalized.

Eosinophil Count Increased, Toxic Skin Eruption (8064436-2)
Patient was taking Primperan Tab. Patient felt the following Primperan side effects: eosinophil count increased, toxic skin eruption on Jan 19, 2012 from FRANCE Additional patient health information: Male , 68 years of age, was diagnosed with
  • hiccups
  • hepatic neoplasm malignant
and. Primperan Tab dosage: 10 Mg, Unk.
Multiple prescriptions taken:
  • Lipiodol (Unk)
  • Valsartan
  • Propranolol
  • Pantoprazole (40 Mg, 1x/day)
  • Doxorubicin Hcl (Unk)
  • Allopurinol
  • Sorafenib (800 Mg, 1x/day)
  • Desloratadine
Patient was hospitalized.

Toxic Skin Eruption, Gastritis, Hyperthermia, Portal Hypertensive Gastropathy, Heart Rate Decreased, Blood Pressure Increased, Hiccups (8021408-1)
Adverse event was reported on Dec 30, 2011 by a Male taking Primperan Tab (Dosage: 10 Mg, Unk) was diagnosed with
  • hiccups
  • hepatic neoplasm malignant
and. Location: FRANCE , 68 years of age, After Primperan was administered, patient encountered several Primperan side effects: toxic skin eruption, gastritis, hyperthermia, portal hypertensive gastropathy, heart rate decreased, blood pressure increased, hiccups.
Multiple concurrent drugs taken:
  • Nexavar (400 Mg, Bid)
  • Valsartan
  • Desloratadine
  • Lipiodol (Unk)
  • Doxorubicin Hcl (Unk)
  • Allopurinol
  • Pantoprazole (40 Mg, Qd)
Patient was hospitalized.

Pancreatitis Acute, Proteinuria, Hypoalbuminaemia, White Blood Cell Count Increased, C-reactive Protein Increased, Haematuria, Glomerulonephropathy, Renal Failure Acute (7972955-X)
on Dec 06, 2011 Male from FRANCE , 51 years of age, was treated with Primperan Tab. Directly after, patient experienced the unwanted or unexpected Primperan side effects: pancreatitis acute, proteinuria, hypoalbuminaemia, white blood cell count increased, c-reactive protein increased, haematuria, glomerulonephropathy, renal failure acute. Primperan Tab dosage: N/A.
Associated medications used:
  • Pf-02341066 (250 Mg, Unk)
  • Esidrix (Unk)
Patient was hospitalized.


Gastrointestinal Disorder, Herpes Zoster (7968823-X)
on Nov 28, 2011 Male from JAPAN , 34 years of age, was diagnosed with
  • abdominal discomfort
and was treated with Primperan Tab. Patient felt the following Primperan side effects: gastrointestinal disorder, herpes zoster. Primperan Tab dosage: N/A.
Multiple prescriptions taken:
  • Motilium
  • Lexiva
  • Ritonavir
  • Truvada
  • Prezista
  • Loperamide Hcl
  • Loxonin
  • Lexiva
Patient was hospitalized.

Nail Avulsion, Pyrexia, Decreased Appetite, Neuropathy Peripheral, Fatigue, Stomatitis, Blood Magnesium Decreased, Colorectal Cancer, Rash (7949493-3)
Patient was taking Primperan Tab. After Primperan was administered, patient encountered several Primperan side effects: nail avulsion, pyrexia, decreased appetite, neuropathy peripheral, fatigue, stomatitis, blood magnesium decreased, colorectal cancer, rash on Nov 16, 2011 from JAPAN Additional patient health information: Male , 76 years of age, weighting 152.1 lb, . Primperan Tab dosage: Unk.
Multiple concurrent drugs taken:
  • Fluorouracil
  • Brotizolam (Unk)
  • Levoleucovorin Calcium
  • Levofloxacin (Unk)
  • Irinotecan Hcl
  • Famotidine (Unk)
  • Lac B (Unk)
  • Fluorouracil


Hyponatraemia, Inappropriate Antidiuretic Hormone Secretion, Diarrhoea, Nausea, Decreased Appetite, Vomiting (7934789-1)
Adverse event was reported on Oct 27, 2011 by a Female taking Primperan Tab (Dosage: N/A) . Location: JAPAN , 51 years of age, weighting 108.9 lb, Directly after, patient experienced the unwanted or unexpected Primperan side effects: hyponatraemia, inappropriate antidiuretic hormone secretion, diarrhoea, nausea, decreased appetite, vomiting.
Associated medications used:
  • Peginterferon Alfa-2b (300 Mg; Bid;unk)
  • Peginterferon Alfa-2b (300 Mg; Bid;unk)
  • Peginterferon Alfa-2b (300 Mg; Bid;unk)
  • Peginterferon Alfa-2b (300 Mg; Bid;unk)
  • Acetaminophen
  • Selbex
  • Potassium Chloride
  • Ensure
Patient was hospitalized.

Henoch-schonlein Purpura (7916953-0)
on Nov 10, 2011 Male from JAPAN , 72 years of age, was treated with Primperan Tab. Patient felt the following Primperan side effects: henoch-schonlein purpura. Primperan Tab dosage: Daily Dose 15 Mg.
Multiple prescriptions taken:
  • Loramet (Daily Dose 1 Mg)
  • Loperamide Hcl (1.0 Mg, Prn)
  • Nexavar (200 Mg, Qd)
  • Cefdinir (Daily Dose 300 Mg)
  • Loxonin (Daily Dose 180 Mg)
  • Lansoprazole (Daily Dose 30 Mg)


Inappropriate Antidiuretic Hormone Secretion (7892456-7)
on Oct 20, 2011 Female from JAPAN , 51 years of age, weighting 108.9 lb, was treated with Primperan /00041901/. After Primperan was administered, patient encountered several Primperan side effects: inappropriate antidiuretic hormone secretion. Primperan /00041901/ dosage: N/A.
Multiple concurrent drugs taken:
  • Ribavirin (Unk;unk)
  • Ribavirin (Unk;unk)
  • Ribavirin (Unk;unk)
  • Ribavirin (Unk;unk)
  • Ribavirin (Unk;unk)
  • Ribavirin (Unk;unk)
  • Ribavirin (Unk;unk)
  • Ribavirin (Unk;unk)
Patient was hospitalized.

Condition Aggravated, Haemolytic Anaemia, Blood Calcium Decreased, Thrombocytopenia, Haemodynamic Instability, Platelet Count Increased, Blood Phosphorus Decreased (7850894-2)
Patient was taking Primperan Tab. Directly after, patient experienced the unwanted or unexpected Primperan side effects: condition aggravated, haemolytic anaemia, blood calcium decreased, thrombocytopenia, haemodynamic instability, platelet count increased, blood phosphorus decreased on Oct 10, 2011 from FRANCE Additional patient health information: Female , 17 years of age, . Primperan Tab dosage: N/A.
Associated medications used:
  • Artesunate (120 Mg; 2/1 Day; Iv)
  • Riamet (1 Dosage Form; 4/1 Day; Po)
  • Ceftriaxone (2 Gram; ; Iv)
  • Acetaminophen (Iv)
Patient was hospitalized.

Biliary Cirrhosis Primary (7816980-8)
Adverse event was reported on Sep 21, 2011 by a Female taking Primperan Tab (Dosage: N/A) . Location: FRANCE , 74 years of age, Patient felt the following Primperan side effects: biliary cirrhosis primary.
Multiple prescriptions taken:
  • Hydrocortisone (Hydrokortison Nycomed Tablet)
  • Voltaren (1 Df : 11.6mg/g,voltaren Gel 11.6mg/g)
  • Lysodren (About A Half Month Later)
  • Oxycodone Hcl
  • Zolpidem Tartrate
  • Fragmin
  • Inderal


Arthralgia, Bone Pain, Blood Immunoglobulin G Increased (7808951-2)
on Oct 03, 2011 Female from GERMANY , 68 years of age, weighting 114.6 lb, was treated with Primperan Tab. After Primperan was administered, patient encountered several Primperan side effects: arthralgia, bone pain, blood immunoglobulin g increased. Primperan Tab dosage: N/A.
Multiple concurrent drugs taken:
  • Erbitux (250mg/m2 15dec10,500mg/m2 28dec,11jan11,12+26apr,10+24may,7+21jun2011)
  • Irinotecan Hcl (7+28dec10,11jan,12+26apr,10+24may,7+21jun11)
  • Fluorouracil (400mg/m2 7dec,08,28dec10,11-11jan11,12-12,26-26apr;10-10,24-24may,07+21jun11,1200mg/m2 7,8,28dec10)
  • Ondansetron (8mg 07+28dec10,11jan,12+26apr,10+24may,7+21jun11)
  • Polaramine (7,15+28dec10,11jan,12+26apr,10+24may,7+21jun11)
  • Calcium Carbonate (7,+28dec10,11jan,12+26apr,10+24may,7+21jun11)
  • Zopiclone
  • Methylprednisolone (120mg 7,+28dec10,11jan,12+26apr,10+24may,7+21jun11)


Tendon Disorder, Peripheral Sensory Neuropathy, Periarthritis (7795346-3)
on Sep 21, 2011 Female from FRANCE , weighting 211.6 lb, was treated with Primperan Tab. Directly after, patient experienced the unwanted or unexpected Primperan side effects: tendon disorder, peripheral sensory neuropathy, periarthritis. Primperan Tab dosage: N/A.
Associated medications used:
  • Neurontin (300 Milligram)
  • Emend
  • Magnesium Sulfate (1 Amp)
  • Magnesium Sulfate (1 Milligram)
  • Magnesium 2 (4 Amp)
  • Pneumococcus Vaccine
  • Ventolin
  • Zofran (8 Milligram)
Patient was hospitalized.

Blood Pressure Decreased (7759127-9)
Patient was taking Primperan Tab. Patient felt the following Primperan side effects: blood pressure decreased on Sep 14, 2011 from JAPAN Additional patient health information: Female , 81 years of age, . Primperan Tab dosage: Unk Ukn, Unk.
Multiple prescriptions taken:
  • Exelon (4.5 Mg Daily)
  • Polycarbophil Calcium (Unk Ukn, Unk)
  • Exelon (Unk Ukn, Unk)
  • Yokukan-san (Unk Ukn, Unk)
  • Ensure (Unk Ukn, Unk)


Platelet Count Decreased, Decreased Appetite, Blood Urine Present, Neutrophil Count Decreased, Malnutrition, Metastases To Spine, Bronchitis, Anaemia, Hypoaesthesia (7752659-9)
Adverse event was reported on Sep 09, 2011 by a Male taking Primperan Tab (Dosage: N/A) . Location: JAPAN , 63 years of age, weighting 143.3 lb, After Primperan was administered, patient encountered several Primperan side effects: platelet count decreased, decreased appetite, blood urine present, neutrophil count decreased, malnutrition, metastases to spine, bronchitis, anaemia, hypoaesthesia.
Multiple concurrent drugs taken:
  • Betamethasone
  • Celestamine Tab
  • Depakene
  • Magnesium Hydroxide Tab
  • Magmitt
  • Temodal (See Image)
  • Temodal (See Image)
  • Temodal (See Image)
Patient was hospitalized and became disabled.

Cardio-respiratory Arrest, Staphylococcal Sepsis, Depression, Nausea, Endocarditis, Clonus, Renal Failure, Appendicitis Perforated, Malaise (7744340-7)
on Aug 19, 2011 Male from FRANCE , 79 years of age, was diagnosed with
  • nausea
and was treated with Primperan Tab. Directly after, patient experienced the unwanted or unexpected Primperan side effects: cardio-respiratory arrest, staphylococcal sepsis, depression, nausea, endocarditis, clonus, renal failure, appendicitis perforated, malaise. Primperan Tab dosage: 1 Df;qd;iv 3 Df;qd. Patient was hospitalized.

Disease Progression, Decreased Appetite (7736573-0)
on Aug 30, 2011 Male from JAPAN , 76 years of age, weighting 87.52 lb, was diagnosed with
  • prostate cancer
and was treated with Primperan Tab. Patient felt the following Primperan side effects: disease progression, decreased appetite. Primperan Tab dosage: N/A.
Multiple prescriptions taken:
  • Oxycontin
  • Zantac
  • Ramelteon
  • Oxycontin
  • Taxotere (Form: Drops)
  • Dexamethasone
  • Paraplatin (Form: Drop)
  • Oxycontin
Patient was hospitalized.

White Blood Cell Count Decreased, Pneumonia, Platelet Count Decreased (7724622-5)
Patient was taking Primperan Tab. After Primperan was administered, patient encountered several Primperan side effects: white blood cell count decreased, pneumonia, platelet count decreased on Aug 30, 2011 from JAPAN Additional patient health information: Male , 70 years of age, weighting 110.2 lb, was diagnosed with
  • prophylaxis
and. Primperan Tab dosage: 10 Mg, 1x/day.
Multiple concurrent drugs taken:
  • Polaramine (5 Mg, 1x/day)
  • Glyceol (200 Ml, 1x/day)
  • Famotidine (20 Mg, 1x/day)
  • Rinderon #1 (4 Mg, 1x/day)
  • Sodium Bicarbonate (2 G, 1x/day)
  • Temsirolimus (25 Mg, 1x/day)
  • Vitamedin Intravenous (1 Ampule, 1x/day)
  • Vitamedin Intravenous


Blood Bilirubin Increased (7688706-2)
Adverse event was reported on Apr 07, 2011 by a Male taking Primperan Tab (Dosage: 30mg Per Day) . Location: JAPAN , weighting 94.80 lb, Directly after, patient experienced the unwanted or unexpected Primperan side effects: blood bilirubin increased.
Associated medications used:
  • Ciprofloxacin Hcl (600mg Per Day)
  • Sulfamethoxazole (2iuax Per Day)
  • Kytril (6mg Per Day)
  • Micardis (40mg Per Day)
  • Furosemide (40mg Per Day)
  • Funguard (150mg Per Day)
  • Neo-minophagen-c (40ml Per Day)
  • Fulcaliq (903ml Per Day)


Headache, Lymphopenia, Hyperthyroidism (7679516-0)
on Aug 05, 2011 Female from FRANCE , 55 years of age, weighting 105.8 lb, was treated with Primperan Tab. Patient felt the following Primperan side effects: headache, lymphopenia, hyperthyroidism. Primperan Tab dosage: N/A.
Multiple prescriptions taken:
  • Ipilimumab
  • Acupan
  • Acetaminophen


Lipase Increased, Ileus, Nausea (7647786-0)
on Jul 28, 2011 Male from NETHERLANDS , 57 years of age, was treated with Primperan Tab. After Primperan was administered, patient encountered several Primperan side effects: lipase increased, ileus, nausea. Primperan Tab dosage: N/A.
Multiple concurrent drugs taken:
  • Oramorph Sr
  • Capecitabine (Interrupted On 12apr11; Restarted On 15apr11)
  • Ondansetron
  • Bms833923 (Interrupted On 12apr11; Restarted 15apr11-unk)
  • Cisplatin
Patient was hospitalized.

White Blood Cell Count Decreased, Pneumonia, Platelet Count Decreased (7644577-1)
Patient was taking Primperan Tab. Directly after, patient experienced the unwanted or unexpected Primperan side effects: white blood cell count decreased, pneumonia, platelet count decreased on Jul 26, 2011 from JAPAN Additional patient health information: Male , 70 years of age, weighting 110.2 lb, was diagnosed with
  • prophylaxis
  • hypophagia
and. Primperan Tab dosage: 10 Mg, 1x/day.
Associated medications used:
  • Vitamedin Intravenous (1 Ampule, 1x/day)
  • Temsirolimus (25 Mg, 1x/day)
  • Hachiazule (2 G, 1x/day)
  • Polaramine (5 Mg, 1x/day)
  • Glyceol (200 Ml, 1x/day)
  • Famotidine (20 Mg, 1x/day)
  • Rinderon #1 (4 Mg, 1x/day)
  • Temsirolimus (25 Mg, 1x/day)


Thrombocytopenia, Condition Aggravated (7641506-1)
Adverse event was reported on Jul 08, 2011 by a Male taking Primperan Tab (Dosage: (df (3 In 1 D) Oral)) . Location: FRANCE , 85 years of age, Patient felt the following Primperan side effects: thrombocytopenia, condition aggravated.
Multiple prescriptions taken:
  • Multaq ((df Oral))
  • Erythrocin ((750 Mg, (250 Mg, 3 In 1 D) Oral))
  • Inexium /01479302/ (inexium) 40 Mg ((80 Mg, 80 Mg (40 Mg, 2 In 1 D) Oral))
Patient was hospitalized.

Thrombocytopenia (7600246-5)
on Jul 01, 2011 Male from FRANCE , 85 years of age, was treated with Primperan Tab. After Primperan was administered, patient encountered several Primperan side effects: thrombocytopenia. Primperan Tab dosage: N/A.
Multiple concurrent drugs taken:
  • Esomeprazole Magnesium
  • Multaq
  • Erythromycin Stearate
Patient was hospitalized.

Hiccups, Rash, Aphagia (7588419-1)
on May 18, 2011 Male from JAPAN , 71 years of age, weighting 141.1 lb, was diagnosed with
  • hiccups
  • hepatic neoplasm malignant
and was treated with Primperan Tab. Directly after, patient experienced the unwanted or unexpected Primperan side effects: hiccups, rash, aphagia. Primperan Tab dosage: 10 Mg.
Associated medications used:
  • Nexavar (200 Mg, Tid)
  • Atarax (25 Mg, Bid)
  • Pastaron (Unk)
  • Atarax (Unk)
  • Phenobarbital Tab (200 Mg)
  • Phenobarbital Tab (100 Mg)
Patient was hospitalized.

Showing 1-25 of 91 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Primperan Information

More About Primperan

Side Effects reported to FDA: 91. View Primperan Adverse Reports

Primperan safety alerts: No

Reported deaths: 27

Reported hospitalizations: 50

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