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Propylene Glycol Side Effects

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Common Propylene Glycol Side Effects



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If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Propylene Glycol Side Effects Reported to FDA



Propylene Glycol Side Effect Report#8653611
Eye Injury, Corneal Abrasion
This is a report of a 63-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Propylene Glycol (dosage: (ophthalmic), start time: 2012), combined with: NA. and developed a serious reaction and side effect(s): Eye Injury, Corneal Abrasion after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Propylene Glycol treatment in female patients, resulting in Eye Injury side effect.
Propylene Glycol Side Effect Report#8477771-0
Eye Injury, Injury Corneal
This report suggests a potential Propylene Glycol Eye Injury side effect(s) that can have serious consequences. A 63-year-old female patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: NA and used Propylene Glycol (dosage: NA) starting
Jan 01, 2012. After starting Propylene Glycol the patient began experiencing various side effects, including: Eye Injury, Injury CornealAdditional drugs used concurrently: NA. Although Propylene Glycol demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Eye Injury, may still occur.
Propylene Glycol Side Effect Report#8462282-9
Medical Device Complication, Uterine Perforation
This Medical Device Complication problem was reported by a consumer or non-health professional from United States. A 32-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Oct 24, 2011 this consumer started treatment with Propylene Glycol (dosage: NA). The following drugs were being taken at the same time:
  • Protonix
  • Advair Diskus 100/50
  • Mirena (Levonorgestrel Daily Intra-uterine)
  • Mirena (Levonorgestrel Daily Intra-uterine)
  • Azelex
  • Rhinocort
When using Propylene Glycol, the patient experienced the following unwanted symptoms/side effects: Medical Device Complication, Uterine PerforationThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Medical Device Complication, may become evident only after a product is in use by the general population.
Propylene Glycol Side Effect Report#8334413-2
Reaction To Preservatives
This Reaction To Preservatives side effect was reported by a consumer or non-health professional from United States. A 67-year-old female patient (weight:NA) experienced the following symptoms/conditions: dry eye,eye inflammation.The patient was prescribed Propylene Glycol (drug dosage: NA), which was initiated on
Mar 07, 2011. Concurrently used drugs:
  • Lotemax
.After starting to take Propylene Glycol the consumer reported adverse symptoms, such as: Reaction To PreservativesThese side effects may potentially be related to Propylene Glycol.
Propylene Glycol Side Effect Report#8283506-7
Renal Failure, Lactic Acidosis, Renal Tubular Necrosis, Accidental Overdose, Acidosis, Hypotension
This is a report of a 50-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Propylene Glycol (dosage: 2 Mg/min During 10 Hours, start time: NS), combined with:
  • Lorazepam (2 Mg/min During 10 Hours)
and developed a serious reaction and side effect(s): Renal Failure, Lactic Acidosis, Renal Tubular Necrosis, Accidental Overdose, Acidosis, Hypotension after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Propylene Glycol treatment in male patients, resulting in Renal Failure side effect. The patient was hospitalized.
Propylene Glycol Side Effect Report#8242425-2
Dyspnoea, Balance Disorder, Headache
This report suggests a potential Propylene Glycol Dyspnoea side effect(s) that can have serious consequences. A male patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: NA and used Propylene Glycol (dosage: Two Doses) starting
Jan 06, 2012. After starting Propylene Glycol the patient began experiencing various side effects, including: Dyspnoea, Balance Disorder, HeadacheAdditional drugs used concurrently:
  • Bisoprolol Fumarate (6.25)
  • Rebif
  • Aspirin
  • Tramadol Hcl (4-6 Times)
  • Soma (Every Evening)
Although Propylene Glycol demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dyspnoea, may still occur.
Propylene Glycol Side Effect Report#8117276-X
Muscle Contractions Involuntary, Bipolar Disorder, Cystitis Interstitial, Restless Legs Syndrome, Tachycardia, Heart Rate Irregular, Dyspnoea Exertional, Serotonin Syndrome, Bladder Disorder
This Muscle Contractions Involuntary problem was reported by a consumer or non-health professional from United States. A 53-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 01, 2008 this consumer started treatment with Propylene Glycol (dosage: NA). The following drugs were being taken at the same time:
  • Armitex Sq
  • Clobax
  • Align
  • Cymbalta (60)
  • Losartan Potassium
  • Elmiron
  • Rustasus (0.5 Cc Bid)
  • Seroquel
When using Propylene Glycol, the patient experienced the following unwanted symptoms/side effects: Muscle Contractions Involuntary, Bipolar Disorder, Cystitis Interstitial, Restless Legs Syndrome, Tachycardia, Heart Rate Irregular, Dyspnoea Exertional, Serotonin Syndrome, Bladder DisorderThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Muscle Contractions Involuntary, may become evident only after a product is in use by the general population.
Propylene Glycol Side Effect Report#8061093-6
Increased Upper Airway Secretion, Odynophagia
This Increased Upper Airway Secretion side effect was reported by a consumer or non-health professional from United States. A 88-year-old female patient (weight:NA) experienced the following symptoms/conditions: dry eye.The patient was prescribed Propylene Glycol (drug dosage: NA), which was initiated on NS. Concurrently used drugs:
  • Restasis (Unk)
  • Thera Tears
  • Tears Naturale
.After starting to take Propylene Glycol the consumer reported adverse symptoms, such as: Increased Upper Airway Secretion, OdynophagiaThese side effects may potentially be related to Propylene Glycol.
Propylene Glycol Side Effect Report#6124513-X
Blood Urine Present, Dermatitis, Feeling Of Body Temperature Change, Gingival Infection, Immunosuppression, Solvent Sensitivity
This is a report of a 56-year-old male patient (weight: NA) from United States, suffering from the following health symptoms/conditions: NA, who was treated with Propylene Glycol (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Blood Urine Present, Dermatitis, Feeling Of Body Temperature Change, Gingival Infection, Immunosuppression, Solvent Sensitivity after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Propylene Glycol treatment in male patients, resulting in Blood Urine Present side effect.



The appearance of Propylene Glycol on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Propylene Glycol reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Propylene Glycol Safety Alerts, Active Ingredients, Usage Information

    More About Propylene glycol

    Side Effects reported to FDA: 9

    Propylene Glycol safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 3

    Latest Propylene Glycol clinical trials

    Propylene Glycol Reviews

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