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Tiredness (6)
Headache (5)
Apathy (4)
Dyspnea (4)
Amnesia (3)
Amnesia, Extremely Tired, Headache (2)
Extremely Tired (2)
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Prozac Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 1761 

Product Quality Issue, Dyspnoea (8395520-1)
on Jun 03, 2011 Female from UNITED STATES , 51 years of age, was treated with Prozac. Directly after, patient experienced the unwanted or unexpected Prozac side effects: product quality issue, dyspnoea. Prozac dosage: N/A.
Associated medications used:
  • Enablex


Hyperhidrosis, Depression (8394339-5)
Patient was taking Prozac. Patient felt the following Prozac side effects: hyperhidrosis, depression on May 24, 2012 from UNITED STATES Additional patient health information: Male , weighting 295.0 lb, was diagnosed with
  • depression
  • routine health maintenance
  • exposure to mould
and. Prozac dosage: N/A.
Multiple prescriptions taken:
  • Multiple Vitamin
  • Sporanox


Osteoarthritis, Joint Dislocation, Bone Disorder, Intervertebral Disc Protrusion, Osteoporosis, Neck Pain, Spinal Osteoarthritis (8379766-4)
Adverse event was reported on May 15, 2012 by a Female taking Prozac (Dosage: N/A) . Location: UNITED STATES , 54 years of age, weighting 269.6 lb, After Prozac was administered, patient encountered several Prozac side effects: osteoarthritis, joint dislocation, bone disorder, intervertebral disc protrusion, osteoporosis, neck pain, spinal osteoarthritis.
Multiple concurrent drugs taken:
  • Aspirin
  • Clonazepam
  • Nexium
  • Nexium
  • Nexium
  • Toprol-xl
Patient was hospitalized.

Basal Cell Carcinoma, Osteonecrosis Of Jaw, Primary Sequestrum, Tenderness, Sinusitis, Glaucoma, Malignant Melanoma In Situ, Clavicle Fracture (8379357-5)
on May 21, 2012 Female from UNITED STATES , weighting 220.0 lb, was treated with Prozac. Directly after, patient experienced the unwanted or unexpected Prozac side effects: basal cell carcinoma, osteonecrosis of jaw, primary sequestrum, tenderness, sinusitis, glaucoma, malignant melanoma in situ, clavicle fracture. Prozac dosage: N/A.
Associated medications used:
  • Zyrtec
  • Chlorhexidine Dental ^aco^ (.12 %, Tid)
  • Prilosec (10 Mg, Qd)
  • Alprazolam (0.25 Mg, Qhs)
  • Ketorolac Tromethamine
  • Coumadin
  • Magnesium Carbonate
  • Celebrex



Dizziness, Convulsion, Diplopia, Migraine (8367731-2)
on May 11, 2012 Female from UNITED STATES , 36 years of age, was treated with Prozac. Patient felt the following Prozac side effects: dizziness, convulsion, diplopia, migraine. Prozac dosage: N/A.
Multiple prescriptions taken:
  • Maxalt
  • Keppra
  • Klonopin
  • Lamictal (500mg See Dosage Text)


Cardiac Disorder (8365532-2)
Patient was taking Prozac. After Prozac was administered, patient encountered several Prozac side effects: cardiac disorder on May 04, 2012 from UNITED STATES Additional patient health information: Male , 59 years of age, . Prozac dosage: N/A.

Weight Decreased (8357794-2)
Adverse event was reported on Apr 11, 2011 by a Female taking Prozac (Dosage: 40 Mg Qd) was diagnosed with
  • depression
  • paroxysmal nocturnal haemoglobinuria
and. Location: UNITED STATES , weighting 593.0 lb, Directly after, patient experienced the unwanted or unexpected Prozac side effects: weight decreased.
Associated medications used:
  • Soliris (600 Mg Qw)
  • Soliris (900 Mg, Q2w)
  • Hydrocortisone (20 Mg Qd)
  • Synthroid (175 Mcg Qd)
  • Metformin Hcl (500 Mg Bid)
  • Fosamax (70 Mg Qw)
  • Florinef (0.1 Mg Qd)
  • Qvar 40 (80 Mg 2 Puffs Bid)


Musculoskeletal Discomfort, Nausea (8356108-1)
on May 16, 2011 Female from UNITED STATES , 49 years of age, weighting 341.7 lb, was treated with Prozac. Patient felt the following Prozac side effects: musculoskeletal discomfort, nausea. Prozac dosage: N/A.
Multiple prescriptions taken:
  • Premarin
  • Protonix
  • Fexofenadine
  • Aspirin
  • Mirapex
  • Etodolac
  • Gilenya (0.5 Mg, Qd, Oral)
  • Calcium


Oedema Peripheral, Joint Swelling, Anxiety, Deep Vein Thrombosis, Pain In Extremity, Formication, Vein Disorder, Fear (8355952-4)
on May 05, 2012 Female from UNITED STATES , 45 years of age, weighting 219.0 lb, was treated with Prozac. After Prozac was administered, patient encountered several Prozac side effects: oedema peripheral, joint swelling, anxiety, deep vein thrombosis, pain in extremity, formication, vein disorder, fear. Prozac dosage: N/A.
Multiple concurrent drugs taken:
  • Yasmin (Unk)
  • Yasmin (Unk)
  • Drospirenone And Ethinyl Estradiol (Unk)
  • Fluoxetine
  • Drospirenone And Ethinyl Estradiol
  • Nexium


Abdominal Discomfort, Abdominal Pain, Back Pain, Dyspnoea, Abdominal Pain Upper (8347468-6)
Patient was taking Prozac. Directly after, patient experienced the unwanted or unexpected Prozac side effects: abdominal discomfort, abdominal pain, back pain, dyspnoea, abdominal pain upper on May 06, 2011 from UNITED STATES Additional patient health information: Male , 37 years of age, . Prozac dosage: N/A.
Associated medications used:
  • Gilenya (0.5 Mg, Qd, Oral)
  • Baclofen


Palpitations, Heart Rate Increased, Anxiety (8347254-7)
Adverse event was reported on Jan 13, 2011 by a Female taking Prozac (Dosage: N/A) . Location: UNITED STATES , 47 years of age, Patient felt the following Prozac side effects: palpitations, heart rate increased, anxiety.
Multiple prescriptions taken:
  • Copaxone
  • Baclofen
  • Gilenya (0.5 Mg, Qd, Oral)


Blood Triglycerides Increased, Anaemia, Blood Cholesterol Increased (8343538-7)
on May 04, 2012 Female from UNITED STATES , weighting 156.5 lb, was diagnosed with
  • depression
and was treated with Prozac. After Prozac was administered, patient encountered several Prozac side effects: blood triglycerides increased, anaemia, blood cholesterol increased. Prozac dosage: Unk.
Multiple concurrent drugs taken:
  • Clonazepam (Unk)
  • Chantix (0.5 Mg, 1x/day)


Sinus Tachycardia, Orthostatic Hypotension, Fall, Syncope, Mydriasis (8341773-5)
on Apr 23, 2012 Male from UNITED STATES , 26 years of age, was diagnosed with
  • tic
and was treated with Prozac. Directly after, patient experienced the unwanted or unexpected Prozac side effects: sinus tachycardia, orthostatic hypotension, fall, syncope, mydriasis. Prozac dosage: 20 Mg, Qd.
Associated medications used:
  • Atomoxetine Hydrochloride (100 Mg, Qd)
Patient was hospitalized.

Abdominal Discomfort, Platelet Count Decreased (8340622-9)
Patient was taking Prozac. Patient felt the following Prozac side effects: abdominal discomfort, platelet count decreased on Sep 24, 2009 from UNITED STATES Additional patient health information: Female , weighting 200.2 lb, . Prozac dosage: N/A.
Multiple prescriptions taken:
  • Treanda
  • Treanda
  • Baclofen
  • Insulin
  • Carafate
  • Phenergan
  • Percocet
  • Folic Acid


Anaphylactic Reaction, Pharyngeal Oedema, Swelling Face (8337371-X)
Adverse event was reported on Apr 26, 2012 by a Male taking Prozac (Dosage: N/A) was diagnosed with
  • depression
  • hepatitis c
and. Location: UNITED STATES , weighting 271.2 lb, After Prozac was administered, patient encountered several Prozac side effects: anaphylactic reaction, pharyngeal oedema, swelling face.
Multiple concurrent drugs taken:
  • Pegasys
  • Incivek
  • Lisinopril
  • Ziac (As Reported: 5-6.25 Mg)
  • Ribavirin


Feeling Jittery, Mood Altered, Insomnia, Asthenia, Headache, Abdominal Pain Upper (8337022-4)
on Jul 29, 2011 Male from UNITED STATES , weighting 154.1 lb, was treated with Prozac. Directly after, patient experienced the unwanted or unexpected Prozac side effects: feeling jittery, mood altered, insomnia, asthenia, headache, abdominal pain upper. Prozac dosage: N/A.
Associated medications used:
  • Nuvigil (25 Milligram;)
  • Nuvigil (50 Milligram;)
  • Nuvigil
  • Nuvigil (75 ;)
  • Nuvigil (50 Milligram;)
  • Klonopin
  • Zyprexa


Tremor (8335044-0)
on Apr 14, 2010 Female from UNITED STATES , weighting 150.1 lb, was diagnosed with
  • depression
  • sleep apnoea syndrome
  • poor peripheral circulation
  • varicose vein
and was treated with Prozac. Patient felt the following Prozac side effects: tremor. Prozac dosage: N/A.
Multiple prescriptions taken:
  • Nuvigil
  • Aspirin (325 Milligram;)
  • Aspirin
  • Vitamin
  • Nuvigil


Vomiting, Asthenia, Nausea (8334409-0)
Patient was taking Prozac. After Prozac was administered, patient encountered several Prozac side effects: vomiting, asthenia, nausea on Jun 09, 2011 from UNITED STATES Additional patient health information: Female , weighting 150.1 lb, . Prozac dosage: N/A.
Multiple concurrent drugs taken:
  • Nuvigil (150 Milligram;)


Nervousness, Anxiety, Panic Attack, Road Traffic Accident, Emotional Disorder, Suicidal Ideation, Insomnia, Fear (8329181-4)
Adverse event was reported on Apr 27, 2012 by a Female taking Prozac (Dosage: Unk) was diagnosed with
  • depression
and. Location: UNITED STATES , weighting 103.0 lb, Directly after, patient experienced the unwanted or unexpected Prozac side effects: nervousness, anxiety, panic attack, road traffic accident, emotional disorder, suicidal ideation, insomnia, fear.
Associated medications used:
  • Valium (Unk)
  • Vistaril (Unk)
  • Xanax (2 Mg, 3x/day)
  • Soma (350 Mg, 3x/day)
  • Xanax (Unk)


Hallucination, Abnormal Dreams (8322749-0)
on Apr 07, 2011 Female from UNITED STATES , weighting 155.1 lb, was diagnosed with
  • depression
  • cerebrovascular accident
and was treated with Prozac. Patient felt the following Prozac side effects: hallucination, abnormal dreams. Prozac dosage: N/A.
Multiple prescriptions taken:
  • Aspirin
  • Toprol-xl
  • Provigil (200 Milligram;)
  • Xanax (.5 Milligram;)
  • Wellbutrin


Ataxia, Back Pain (8321739-1)
on Apr 23, 2012 Female from UNITED STATES , 54 years of age, was treated with Prozac. After Prozac was administered, patient encountered several Prozac side effects: ataxia, back pain. Prozac dosage: N/A.
Multiple concurrent drugs taken:
  • Gilenya


Suicide Attempt, Emotional Disorder, Somnolence, Overdose, Feeling Abnormal (8317002-5)
Patient was taking Prozac. Directly after, patient experienced the unwanted or unexpected Prozac side effects: suicide attempt, emotional disorder, somnolence, overdose, feeling abnormal on Apr 13, 2012 from UNITED STATES Additional patient health information: Female , 49 years of age, weighting 155.0 lb, . Prozac dosage: N/A.
Associated medications used:
  • Ziprasidone Hydrochloride (geodon) (60 Mg (6 Mg, 1 In 1 D), Oral)
  • Celexa
  • Risperidone
  • Ambien
  • Hydroxyzine Hydrochloride
  • Depakote
Patient was hospitalized.

Blood Cholesterol Increased, Headache (8316330-7)
Adverse event was reported on Apr 24, 2012 by a Female taking Prozac (Dosage: Unk) . Location: UNITED STATES , weighting 125.7 lb, Patient felt the following Prozac side effects: blood cholesterol increased, headache.
Multiple prescriptions taken:
  • Myfortic (Unk)
  • Lipitor (20 Mg, Once Daily)
  • Zocor (Unk)


Hypomania (8313767-7)
on Aug 08, 2011 Male from UNITED STATES , 36 years of age, was diagnosed with
  • depression
and was treated with Prozac. After Prozac was administered, patient encountered several Prozac side effects: hypomania. Prozac dosage: 80 Milligram;.
Multiple concurrent drugs taken:
  • Provigil (100 Milligram;)


Hallucination, Visual, Anxiety (8313758-6)
on Aug 08, 2011 Male from UNITED STATES , weighting 269.0 lb, was diagnosed with
  • attention deficit/hyperactivity disorder
  • fatigue
and was treated with Prozac. Directly after, patient experienced the unwanted or unexpected Prozac side effects: hallucination, visual, anxiety. Prozac dosage: 40 Milligram;.
Associated medications used:
  • Provigil
  • Concerta (36 Milligram;)
  • Provigil (100 Milligram;)


Showing 1-25 of 1761 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Prozac Information

Alternative PROZAC Names:FLUOXETIN

Active Ingredient: FLUOXETIN

Prozac Dosage, Warnings, Usage.

Side Effects reported to FDA: 1761. View Prozac Adverse Reports

Prozac safety alerts: 2005

Reported deaths: 213

Reported hospitalizations: 640

Prozac (fluoxetine)

Audience: Neuropsychiatric healthcare professionals and consumers

[UPDATE 07/08/2005] FDA notified healthcare professionals about the availability of updated Healthcare Professional and Patient Information Sheets for antidepressant medications that were the subject of a June 30, 2005 Public Health Advisory issued about the risk of suicidality (suicidal thinking or behavior) in adults being treated with antidepressant medications.

[Posted 07/01/2005] In response to recent scientific publications that report the possibility of increased risk of suicidal behavior in adults treated with antidepressants, the FDA has issued a Public Health Advisory to update patients and healthcare providers with the latest information on this subject. Even before the publication of these recent reports, FDA had already begun the process of reviewing available data to determine whether there is an increased risk of suicidal behavior in adults taking antidepressants. The Agency has asked manufacturers to provide information from their trials using an approach similar to that used in the evaluation of the risk of suicidal behavior in the pediatric population taking antidepressants. This effort will involve hundreds of clinical trials and may take more than a year to complete.

[July 08, 2005 - Healthcare Professional and Patient Information Sheets - FDA]
[June 30, 2005 - Public Health Advisory - FDA]
[June 30, 2005 - Drug Information Page - FDA]


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