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Diarrehea (20)
Drowsiness (12)
Nausea (12)
Upset Stomach (8)
Altered Taste (6)
Diarrhea (6)
Douleur Urinoire (6)
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Pyostacine Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 38 

Condition Aggravated, Nasal Abscess, Cellulitis, Oedema (8479546-5)
on Jun 29, 2012 Female from FRANCE , 48 years of age, was diagnosed with
  • nasal abscess
and was treated with Pyostacine. Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: condition aggravated, nasal abscess, cellulitis, oedema. Pyostacine dosage: Unk.
Associated medications used:
  • Ibuprofen (advil) (400 Mg, 3x/day)
Patient was hospitalized.

Vomiting, Gastric Ulcer Haemorrhage, Dizziness, Melaena, Arthritis, Duodenal Ulcer, Hiatus Hernia, Haematuria (8413556-9)
Patient was taking Pyostacine. Patient felt the following Pyostacine side effects: vomiting, gastric ulcer haemorrhage, dizziness, melaena, arthritis, duodenal ulcer, hiatus hernia, haematuria on May 25, 2012 from FRANCE Additional patient health information: Male , weighting 114.6 lb, . Pyostacine dosage: 1g Twice Per Day.
Multiple prescriptions taken:
  • Domperidone (20mg Three Times Per Day)
  • Trimebutine (200mg Three Times Per Day)
  • Desloratadine (5mg Twice Per Day)
  • Acetaminophen And Codeine Phosphate
  • Arixtra (7.5mg Per Day)
  • Altizide + Spironolactone (1unit In The Morning)
Patient was hospitalized.

Posterior Reversible Encephalopathy Syndrome (8383067-8)
Adverse event was reported on May 11, 2012 by a Female taking Pyostacine (Dosage: N/A) . Location: FRANCE , 56 years of age, After Pyostacine was administered, patient encountered several Pyostacine side effects: posterior reversible encephalopathy syndrome.
Multiple concurrent drugs taken:
  • Lexomil
  • Lyrica
  • Lyrica
  • Keppra
  • Tramadol Hcl
  • Citalopram Hydrobromide
  • Oxynorm
  • Prednisolone
Patient was hospitalized.

Dermatitis Exfoliative (8297302-8)
on Apr 03, 2012 Female from FRANCE , 85 years of age, was diagnosed with
  • pyelonephritis
and was treated with Pyostacine (pristinamycin) (pristinamycin). Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: dermatitis exfoliative. Pyostacine (pristinamycin) (pristinamycin) dosage: 3 Gm (1 Gm, 3 In 1 D), Oral.
Associated medications used:
  • Levothyrox 75 (levothyroxine Sodium) (tablet) (levothyroxine Sodium) (75 Mcg (75 Mcg 1 In 1 D), Oral)
  • Lasilix Special (furosemide) (500 Mg, Tablet) (furosemide) (250 Mg (250 Mg, 1 In 1 D), Oral)
Patient was hospitalized.


Cytolytic Hepatitis, Hepatitis Cholestatic (8296482-8)
on Apr 16, 2012 Male from FRANCE , 82 years of age, was treated with Pyostacine. Patient felt the following Pyostacine side effects: cytolytic hepatitis, hepatitis cholestatic. Pyostacine dosage: 500 Mg, 3x/day.
Multiple prescriptions taken:
  • Oxycodone Hcl (10 Mg, 1x/day)
  • Nexium
  • Aspirin
  • Potassium Chloride (1000 Mg, 1x/day)
  • Plavix
  • Solu-medrol (90 Mg, 1x/day)
  • Amoxicillin Trihydrate (2 G, 3x/day)
  • Ofloxacin (200 Mg, 2x/day)
Patient was hospitalized.

Pyrexia, Cardiac Failure, Erythema, Pruritus, Rales, Rash Macular, Tachycardia (8271091-5)
Patient was taking Pyostacine. After Pyostacine was administered, patient encountered several Pyostacine side effects: pyrexia, cardiac failure, erythema, pruritus, rales, rash macular, tachycardia on Apr 04, 2012 from FRANCE Additional patient health information: Female , 64 years of age, was diagnosed with
  • antibiotic prophylaxis
  • pain
and. Pyostacine dosage: Unk.
Multiple concurrent drugs taken:
  • Tramadol Hcl (150 Mg, As Needed)
  • Digoxin (1 Df, 1x/day)
  • Repaglinide (1 Mg, 3x/day)
  • Amoxicillin Trihydrate (Unk)
  • Zithromax (250 Mg, 2 Tablets Per Week)
  • Captopril (25 Mg, 1x/day)
  • Previscan
  • Nozinan (4% Oral Solution 20 Gtt, At Bedtime)
Patient was hospitalized.

Odynophagia, Pyrexia, Agranulocytosis (8269370-0)
Adverse event was reported on Mar 28, 2012 by a Female taking Pyostacine (Dosage: N/A) was diagnosed with
  • pyrexia
and. Location: FRANCE , weighting 114.6 lb, Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: odynophagia, pyrexia, agranulocytosis.
Associated medications used:
  • Meteospasmyl
  • Mabthera (Second Course)
  • Mabthera (Sixth Course)
  • Mabthera (Seventh Course)
  • Nexium
  • Colposeptine
  • Mabthera (Third Course)
  • Mabthera (Eighth Course)
Patient was hospitalized.

Condition Aggravated, Renal Failure, Eosinophilia (8217375-8)
on Feb 28, 2012 Female from DENMARK , 55 years of age, was diagnosed with
  • erysipelas
and was treated with Pyostacine (pristinamycin). Patient felt the following Pyostacine side effects: condition aggravated, renal failure, eosinophilia. Pyostacine (pristinamycin) dosage: Po.
Multiple prescriptions taken:
  • Clindamycin Hcl
  • Piperacillin And Tazobactam
  • Amoxicillin
  • Ramipril (Po)
Patient was hospitalized.

Asthenia, Blood Creatinine Increased, Neutropenia, Erysipelas, Bullous Impetigo, Cd4 Lymphocytes Decreased, Leukopenia, Cellulitis, Wound Infection (8022619-1)
on Dec 19, 2011 Male from FRANCE , 50 years of age, weighting 134.5 lb, was treated with Pyostacine (pristinamycin). After Pyostacine was administered, patient encountered several Pyostacine side effects: asthenia, blood creatinine increased, neutropenia, erysipelas, bullous impetigo, cd4 lymphocytes decreased, leukopenia, cellulitis, wound infection. Pyostacine (pristinamycin) dosage: Tid.
Multiple concurrent drugs taken:
  • Reyataz
  • Peginterferon Alfa-2b (0.5 Ml;qw)
  • Truvada
  • Boceprevir (sch-503034) (800 Mg;tid)
  • Rebetol (400 Mg;bid)
  • Emtriva
  • Norvir
  • Desloratadine
Patient was hospitalized.

Maternal Exposure During Pregnancy (7946439-9)
Patient was taking Pyostacine (pristinamycin). Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: maternal exposure during pregnancy on Nov 10, 2011 from SWITZERLAND Additional patient health information: Female , 17 years of age, was diagnosed with
  • pruritus
and. Pyostacine (pristinamycin) dosage: N/A.
Associated medications used:
  • Locoid (Topical)


Maternal Exposure During Pregnancy (7935833-8)
Adverse event was reported on Nov 07, 2011 by a Female taking Pyostacine (pristinamycin) (Dosage: 500 Mg, /d, Transplacental) was diagnosed with
  • pruritus
and. Location: SWITZERLAND , 17 years of age, Patient felt the following Pyostacine side effects: maternal exposure during pregnancy.
Multiple prescriptions taken:
  • Locoid (Topical)


Sepsis, Skin Infection (7890058-X)
on Oct 31, 2011 Male from UNITED STATES , weighting 127.9 lb, was diagnosed with
  • ulcer
  • pain
and was treated with Pyostacine. After Pyostacine was administered, patient encountered several Pyostacine side effects: sepsis, skin infection. Pyostacine dosage: Unk.
Multiple concurrent drugs taken:
  • Acetaminophen (1000 Mg, Prn)
  • Perikabiven (800 Kcal)
  • Nexium (20 Mg, Unk)
  • Potassium Chloride (312 Mg, Unk)
  • Gemcitabine Hydrochloride (1000 Mg/m2, Qd)
  • Oxycodone Hcl (Unk Unk, Prn)
  • Motilium (30 Mg, Tid)
  • Duragesic-100 (Unk Unk, Tid)
Patient was hospitalized.

Nikolsky's Sign, Erythema, Toxic Skin Eruption (7750143-X)
on Sep 09, 2011 Male from FRANCE , 73 years of age, was treated with Pyostacine. Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: nikolsky's sign, erythema, toxic skin eruption. Pyostacine dosage: Unk.
Associated medications used:
  • Ciprofloxacin (Unk)
  • Amikacin (Unk)
  • Speciafoldine
  • Pantoprazole
  • Acetaminophen
  • Duragesic-100
  • Ferrous Sulfate Tab
  • Piperacillin And Tazobactam (Unk)
Patient was hospitalized.

Palmar-plantar Erythrodysaesthesia Syndrome, Hyponatraemia, Coma, Hypokalaemia, Convulsion, Inappropriate Antidiuretic Hormone Secretion (7554364-0)
Patient was taking Pyostacine. Patient felt the following Pyostacine side effects: palmar-plantar erythrodysaesthesia syndrome, hyponatraemia, coma, hypokalaemia, convulsion, inappropriate antidiuretic hormone secretion on Jun 14, 2011 from FRANCE Additional patient health information: Female , weighting 127.9 lb, was diagnosed with
  • cough
and. Pyostacine dosage: Other Indication: Bronchitis..
Multiple prescriptions taken:
  • Pneumorel (Other Indication: Bronchitis.)
  • Lercanidipine
  • Nicardipine Hcl
  • Xeloda
  • Aredia
  • Xeloda
  • Kardegic
Patient was hospitalized.

Diarrhoea, Fall, Hypotension, Renal Failure Acute, Vomiting (7132499-4)
Adverse event was reported on Nov 24, 2010 by a Female taking Pyostacine (Dosage: N/A) was diagnosed with
  • infection
and. Location: FRANCE , 83 years of age, After Pyostacine was administered, patient encountered several Pyostacine side effects: diarrhoea, fall, hypotension, renal failure acute, vomiting.
Multiple concurrent drugs taken:
  • Lasix
  • Ixprim
  • Lyrica
  • Lisinopril And Hydrochlorothiazide
  • Zanidip
Patient was hospitalized.

Leukocytoclastic Vasculitis (6248953-3)
on Jun 15, 2009 Male from , 52 years of age, was diagnosed with
  • erysipelas
and was treated with Pyostacine. Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: leukocytoclastic vasculitis. Pyostacine dosage: N/A.
Associated medications used:
  • Torental
  • Tracleer
  • Tracleer
Patient was hospitalized.

Colitis, International Normalised Ratio Increased, Rectal Haemorrhage (6209987-8)
on May 25, 2009 Female from , 84 years of age, was treated with Pyostacine. Patient felt the following Pyostacine side effects: colitis, international normalised ratio increased, rectal haemorrhage. Pyostacine dosage: N/A.
Multiple prescriptions taken:
  • Lovenox
  • Hydrocortisone /00028607/
  • Previscan /00789001/
  • Kardegic /00002703/
  • Clamoxyl /00249601/
  • Paracetamol
  • Topalgic
  • Bricanyl
Patient was hospitalized.

Erythema, Skin Exfoliation, Toxic Epidermal Necrolysis (6165594-7)
Patient was taking Pyostacine. After Pyostacine was administered, patient encountered several Pyostacine side effects: erythema, skin exfoliation, toxic epidermal necrolysis on Apr 09, 2009 from Additional patient health information: Female , 80 years of age, was diagnosed with
  • hyperthermia
and. Pyostacine dosage: N/A.
Multiple concurrent drugs taken:
  • Lasilix /00032601/
  • Cortancyl
  • Norset
  • Prazepam
  • Lepticur
  • Celectol
  • Laxatives
  • Previscan /00789001/
Patient was hospitalized.

Colitis, International Normalised Ratio Increased, Rectal Haemorrhage (6072075-8)
Adverse event was reported on Feb 02, 2009 by a Female taking Pyostacine (Dosage: N/A) . Location: , 84 years of age, Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: colitis, international normalised ratio increased, rectal haemorrhage.
Associated medications used:
  • Lovenox
  • Hydrocortisone /00028607/
  • Previscan /00789001/
  • Kardegic /00002703/
  • Clamoxyl /00249601/
  • Paracetamol
  • Topalgic
  • Bricanyl
Patient was hospitalized.

Fall, Nausea (5700620-8)
on Apr 01, 2008 Female from , 52 years of age, was treated with Pyostacine. Patient felt the following Pyostacine side effects: fall, nausea. Pyostacine dosage: N/A.
Multiple prescriptions taken:
  • Ketek
  • Flanid
Patient was hospitalized.

Condition Aggravated, Rash Pustular (5641071-4)
on Feb 18, 2008 Female from , 94 years of age, was treated with Pyostacine. After Pyostacine was administered, patient encountered several Pyostacine side effects: condition aggravated, rash pustular. Pyostacine dosage: N/A.
Multiple concurrent drugs taken:
  • Lasilix /00032601/
  • Lanzor
  • Cordarone
  • Kardegic /00002703/
  • Tiapridal /00435701/
  • Forlax
  • Noctran
  • Dermoval /00337102/
Patient was hospitalized.

Condition Aggravated, Rash Pustular (5585627-6)
Patient was taking Pyostacine. Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: condition aggravated, rash pustular on Jan 02, 2008 from Additional patient health information: Female , 94 years of age, . Pyostacine dosage: N/A.
Associated medications used:
  • Lasix
  • Lanzor
  • Cordarone
  • Kardegic /00002703/
  • Tiapridal /00435701/
  • Forlax
  • Noctran
  • Dermoval /00337102/
Patient was hospitalized.

Asthenia, Eosinophilia, Face Oedema, Inflammation, Nephritis Interstitial, Odynophagia, Pruritus, Purpura (5472754-7)
Adverse event was reported on Sep 21, 2007 by a Male taking Pyostacine (Dosage: N/A) . Location: , 71 years of age, Patient felt the following Pyostacine side effects: asthenia, eosinophilia, face oedema, inflammation, nephritis interstitial, odynophagia, pruritus, purpura.
Multiple prescriptions taken:
  • Lovenox
  • Vancomycin
  • Josir
  • Gaviscon /01405501/
  • Rifadin
  • Oflocet /00731801/
  • Imovane
  • Topalgic
Patient was hospitalized.

Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Gamma-glutamyltransferase Increased, Liver Disorder, Pruritus (5276883-2)
on Mar 22, 2007 Female from , 40 years of age, weighting 238.1 lb, was treated with Pyostacine. After Pyostacine was administered, patient encountered several Pyostacine side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, liver disorder, pruritus. Pyostacine dosage: N/A.
Multiple concurrent drugs taken:
  • Lovenox
  • Dafalgan /00020001/
Patient was hospitalized.

Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Gamma-glutamyltransferase Increased, Liver Disorder, Pruritus (5217041-7)
on Jan 19, 2007 Female from , 40 years of age, weighting 238.1 lb, was treated with Pyostacine. Directly after, patient experienced the unwanted or unexpected Pyostacine side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, liver disorder, pruritus. Pyostacine dosage: N/A.
Associated medications used:
  • Lovenox
  • Dafalgan /00020001/
Patient was hospitalized.

Showing 1-25 of 38 

Pyostacine Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pyostacine Information

More About Pyostacine

Side Effects reported to FDA: 38. View Pyostacine Adverse Reports

Pyostacine safety alerts: No

Reported deaths: 1

Reported hospitalizations: 28

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