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Pyostacine Side Effects

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Common Pyostacine Side Effects


The most commonly reported Pyostacine side effects (click to view or check a box to report):

Pruritus (7)
Eosinophilia (6)
Deafness Bilateral (5)
Condition Aggravated (5)
Alanine Aminotransferase Increased (4)
Erythema (4)
Diarrhoea (4)
Gastrointestinal Disorder (3)
Aspartate Aminotransferase Increased (3)
Gamma-glutamyltransferase Increased (3)
Nausea (3)
Liver Disorder (3)
Vomiting (3)
Visual Field Defect (3)
Pyrexia (2)
Rash Pustular (2)
Odynophagia (2)
International Normalised Ratio Increased (2)
Hypotension (2)
Maternal Exposure During Pregnancy (2)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Pyostacine Side Effects Reported to FDA



Pyostacine Side Effect Report#9669202
Angioedema, Blood Pressure Decreased, Respiratory Gas Exchange Disorder
This is a report of a 76-year-old female patient (weight: NA) from FR, suffering from the following health symptoms/conditions: wound infection, who was treated with Pyostacine (dosage: NA, start time:
Sep 30, 2013), combined with:
  • Rifadine
and developed a serious reaction and side effect(s): Angioedema, Blood Pressure Decreased, Respiratory Gas Exchange Disorder after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Pyostacine treatment in female patients, resulting in Angioedema side effect.
Pyostacine Side Effect Report#9213914
Hypovolaemic Shock, Hypotension, Renal Failure Acute, Diarrhoea, Vomiting, Ventricular Hyperkinesia, Dehydration, Gastrointestinal Disorder
This report suggests a potential Pyostacine Hypovolaemic Shock side effect(s) that can have serious consequences. A 63-year-old male patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: cough and used Pyostacine (dosage: NA) starting
Feb 22, 2013. After starting Pyostacine the patient began experiencing various side effects, including: Hypovolaemic Shock, Hypotension, Renal Failure Acute, Diarrhoea, Vomiting, Ventricular Hyperkinesia, Dehydration, Gastrointestinal DisorderAdditional drugs used concurrently:
  • Lasilix
  • Perindopril
  • Kardegic
  • Allopurinol
  • Adenuric
  • Epoetin Beta (Every 15 Days)
  • Cardensiel
The patient was hospitalized. Although Pyostacine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hypovolaemic Shock, may still occur.
Pyostacine Side Effect Report#8479546-5
Condition Aggravated, Nasal Abscess, Cellulitis, Oedema
This Condition Aggravated problem was reported by a health professional from France. A 48-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: nasal abscess. On
Apr 09, 2012 this consumer started treatment with Pyostacine (dosage: Unk). The following drugs were being taken at the same time:
  • Ibuprofen (advil) (400 Mg, 3x/day)
When using Pyostacine, the patient experienced the following unwanted symptoms/side effects: Condition Aggravated, Nasal Abscess, Cellulitis, OedemaThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Condition Aggravated, may become evident only after a product is in use by the general population.
Pyostacine Side Effect Report#8413556-9
Vomiting, Gastric Ulcer Haemorrhage, Dizziness, Melaena, Arthritis, Duodenal Ulcer, Hiatus Hernia, Haematuria
This Vomiting side effect was reported by a physician from France. A male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Pyostacine (drug dosage: 1g Twice Per Day), which was initiated on
Dec 01, 2011. Concurrently used drugs:
  • Domperidone (20mg Three Times Per Day)
  • Trimebutine (200mg Three Times Per Day)
  • Desloratadine (5mg Twice Per Day)
  • Acetaminophen And Codeine Phosphate
  • Arixtra (7.5mg Per Day)
  • Altizide + Spironolactone (1unit In The Morning)
.After starting to take Pyostacine the consumer reported adverse symptoms, such as: Vomiting, Gastric Ulcer Haemorrhage, Dizziness, Melaena, Arthritis, Duodenal Ulcer, Hiatus Hernia, HaematuriaThese side effects may potentially be related to Pyostacine. The patient was hospitalized.
Pyostacine Side Effect Report#8383067-8
Posterior Reversible Encephalopathy Syndrome
This is a report of a 56-year-old female patient (weight: NA) from France, suffering from the following health symptoms/conditions: NA, who was treated with Pyostacine (dosage: NA, start time:
Jan 31, 2012), combined with:
  • Lexomil
  • Lyrica
  • Lyrica
  • Keppra
  • Tramadol Hcl
  • Citalopram Hydrobromide
  • Oxynorm
  • Prednisolone
and developed a serious reaction and side effect(s): Posterior Reversible Encephalopathy Syndrome after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Pyostacine treatment in female patients, resulting in Posterior Reversible Encephalopathy Syndrome side effect. The patient was hospitalized.
Pyostacine Side Effect Report#8297302-8
Dermatitis Exfoliative
This report suggests a potential Pyostacine (pristinamycin) (pristinamycin) Dermatitis Exfoliative side effect(s) that can have serious consequences. A 85-year-old female patient (weight: NA) from France was diagnosed with the following symptoms/conditions: pyelonephritis and used Pyostacine (pristinamycin) (pristinamycin) (dosage: 3 Gm (1 Gm, 3 In 1 D), Oral) starting
Dec 07, 2011. After starting Pyostacine (pristinamycin) (pristinamycin) the patient began experiencing various side effects, including: Dermatitis ExfoliativeAdditional drugs used concurrently:
  • Levothyrox 75 (levothyroxine Sodium) (tablet) (levothyroxine Sodium) (75 Mcg (75 Mcg 1 In 1 D), Oral)
  • Lasilix Special (furosemide) (500 Mg, Tablet) (furosemide) (250 Mg (250 Mg, 1 In 1 D), Oral)
The patient was hospitalized. Although Pyostacine (pristinamycin) (pristinamycin) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dermatitis Exfoliative, may still occur.
Pyostacine Side Effect Report#8296482-8
Cytolytic Hepatitis, Hepatitis Cholestatic
This Cytolytic Hepatitis problem was reported by a health professional from France. A 82-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Feb 27, 2012 this consumer started treatment with Pyostacine (dosage: 500 Mg, 3x/day). The following drugs were being taken at the same time:
  • Oxycodone Hcl (10 Mg, 1x/day)
  • Nexium
  • Aspirin
  • Potassium Chloride (1000 Mg, 1x/day)
  • Plavix
  • Solu-medrol (90 Mg, 1x/day)
  • Amoxicillin Trihydrate (2 G, 3x/day)
  • Ofloxacin (200 Mg, 2x/day)
When using Pyostacine, the patient experienced the following unwanted symptoms/side effects: Cytolytic Hepatitis, Hepatitis CholestaticThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Cytolytic Hepatitis, may become evident only after a product is in use by the general population.
Pyostacine Side Effect Report#8271091-5
Pyrexia, Cardiac Failure, Erythema, Pruritus, Rales, Rash Macular, Tachycardia
This Pyrexia side effect was reported by a health professional from France. A 64-year-old female patient (weight:NA) experienced the following symptoms/conditions: antibiotic prophylaxis,pain.The patient was prescribed Pyostacine (drug dosage: Unk), which was initiated on
Jan 09, 2012. Concurrently used drugs:
  • Tramadol Hcl (150 Mg, As Needed)
  • Digoxin (1 Df, 1x/day)
  • Repaglinide (1 Mg, 3x/day)
  • Amoxicillin Trihydrate (Unk)
  • Zithromax (250 Mg, 2 Tablets Per Week)
  • Captopril (25 Mg, 1x/day)
  • Previscan
  • Nozinan (4% Oral Solution 20 Gtt, At Bedtime)
.After starting to take Pyostacine the consumer reported adverse symptoms, such as: Pyrexia, Cardiac Failure, Erythema, Pruritus, Rales, Rash Macular, TachycardiaThese side effects may potentially be related to Pyostacine. The patient was hospitalized.
Pyostacine Side Effect Report#8269370-0
Odynophagia, Pyrexia, Agranulocytosis
This is a report of a female patient (weight: NA) from France, suffering from the following health symptoms/conditions: pyrexia, who was treated with Pyostacine (dosage: NA, start time:
Jun 17, 2008), combined with:
  • Meteospasmyl
  • Mabthera (Second Course)
  • Mabthera (Sixth Course)
  • Mabthera (Seventh Course)
  • Nexium
  • Colposeptine
  • Mabthera (Third Course)
  • Mabthera (Eighth Course)
and developed a serious reaction and side effect(s): Odynophagia, Pyrexia, Agranulocytosis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Pyostacine treatment in female patients, resulting in Odynophagia side effect. The patient was hospitalized.
Pyostacine Side Effect Report#8217375-8
Condition Aggravated, Renal Failure, Eosinophilia
This report suggests a potential Pyostacine (pristinamycin) Condition Aggravated side effect(s) that can have serious consequences. A 55-year-old female patient (weight: NA) from Denmark was diagnosed with the following symptoms/conditions: erysipelas and used Pyostacine (pristinamycin) (dosage: Po) starting
Jan 27, 2012. After starting Pyostacine (pristinamycin) the patient began experiencing various side effects, including: Condition Aggravated, Renal Failure, EosinophiliaAdditional drugs used concurrently:
  • Clindamycin Hcl
  • Piperacillin And Tazobactam
  • Amoxicillin
  • Ramipril (Po)
The patient was hospitalized. Although Pyostacine (pristinamycin) demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Condition Aggravated, may still occur.
Pyostacine Side Effect Report#8022619-1
Asthenia, Blood Creatinine Increased, Neutropenia, Erysipelas, Bullous Impetigo, Cd4 Lymphocytes Decreased, Leukopenia, Cellulitis, Wound Infection
This Asthenia problem was reported by a physician from France. A 50-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Sep 09, 2011 this consumer started treatment with Pyostacine (pristinamycin) (dosage: Tid). The following drugs were being taken at the same time:
  • Reyataz
  • Peginterferon Alfa-2b (0.5 Ml;qw)
  • Truvada
  • Boceprevir (sch-503034) (800 Mg;tid)
  • Rebetol (400 Mg;bid)
  • Emtriva
  • Norvir
  • Desloratadine
When using Pyostacine (pristinamycin), the patient experienced the following unwanted symptoms/side effects: Asthenia, Blood Creatinine Increased, Neutropenia, Erysipelas, Bullous Impetigo, Cd4 Lymphocytes Decreased, Leukopenia, Cellulitis, Wound InfectionThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Asthenia, may become evident only after a product is in use by the general population.
Pyostacine Side Effect Report#7946439-9
Maternal Exposure During Pregnancy
This Maternal Exposure During Pregnancy side effect was reported by a consumer or non-health professional from Switzerland. A 17-year-old female patient (weight:NA) experienced the following symptoms/conditions: pruritus.The patient was prescribed Pyostacine (pristinamycin) (drug dosage: NA), which was initiated on
Nov 01, 2010. Concurrently used drugs:
  • Locoid (Topical)
.After starting to take Pyostacine (pristinamycin) the consumer reported adverse symptoms, such as: Maternal Exposure During PregnancyThese side effects may potentially be related to Pyostacine (pristinamycin).
Pyostacine Side Effect Report#7935833-8
Maternal Exposure During Pregnancy
This is a report of a 17-year-old female patient (weight: NA) from Switzerland, suffering from the following health symptoms/conditions: pruritus, who was treated with Pyostacine (pristinamycin) (dosage: 500 Mg, /d, Transplacental, start time:
Nov 01, 2010), combined with:
  • Locoid (Topical)
and developed a serious reaction and side effect(s): Maternal Exposure During Pregnancy after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Pyostacine (pristinamycin) treatment in female patients, resulting in Maternal Exposure During Pregnancy side effect.
Pyostacine Side Effect Report#7890058-X
Sepsis, Skin Infection
This report suggests a potential Pyostacine Sepsis side effect(s) that can have serious consequences. A male patient (weight: NA) from United States was diagnosed with the following symptoms/conditions: ulcer,pain and used Pyostacine (dosage: Unk) starting
Jun 07, 2011. After starting Pyostacine the patient began experiencing various side effects, including: Sepsis, Skin InfectionAdditional drugs used concurrently:
  • Acetaminophen (1000 Mg, Prn)
  • Perikabiven (800 Kcal)
  • Nexium (20 Mg, Unk)
  • Potassium Chloride (312 Mg, Unk)
  • Gemcitabine Hydrochloride (1000 Mg/m2, Qd)
  • Oxycodone Hcl (Unk Unk, Prn)
  • Motilium (30 Mg, Tid)
  • Duragesic-100 (Unk Unk, Tid)
The patient was hospitalized. Although Pyostacine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Sepsis, may still occur.
Pyostacine Side Effect Report#7750143-X
Nikolsky's Sign, Erythema, Toxic Skin Eruption
This Nikolsky's Sign problem was reported by a health professional from France. A 73-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
May 28, 2011 this consumer started treatment with Pyostacine (dosage: Unk). The following drugs were being taken at the same time:
  • Ciprofloxacin (Unk)
  • Amikacin (Unk)
  • Speciafoldine
  • Pantoprazole
  • Acetaminophen
  • Duragesic-100
  • Ferrous Sulfate Tab
  • Piperacillin And Tazobactam (Unk)
When using Pyostacine, the patient experienced the following unwanted symptoms/side effects: Nikolsky's Sign, Erythema, Toxic Skin EruptionThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Nikolsky's Sign, may become evident only after a product is in use by the general population.
Pyostacine Side Effect Report#7554364-0
Palmar-plantar Erythrodysaesthesia Syndrome, Hyponatraemia, Coma, Hypokalaemia, Convulsion, Inappropriate Antidiuretic Hormone Secretion
This Palmar-plantar Erythrodysaesthesia Syndrome side effect was reported by a physician from France. A female patient (weight:NA) experienced the following symptoms/conditions: cough.The patient was prescribed Pyostacine (drug dosage: Other Indication: Bronchitis.), which was initiated on
Mar 01, 2009. Concurrently used drugs:
  • Pneumorel (Other Indication: Bronchitis.)
  • Lercanidipine
  • Nicardipine Hcl
  • Xeloda
  • Aredia
  • Xeloda
  • Kardegic
.After starting to take Pyostacine the consumer reported adverse symptoms, such as: Palmar-plantar Erythrodysaesthesia Syndrome, Hyponatraemia, Coma, Hypokalaemia, Convulsion, Inappropriate Antidiuretic Hormone SecretionThese side effects may potentially be related to Pyostacine. The patient was hospitalized.
Pyostacine Side Effect Report#7132499-4
Diarrhoea, Fall, Hypotension, Renal Failure Acute, Vomiting
This is a report of a 83-year-old female patient (weight: NA) from France, suffering from the following health symptoms/conditions: infection, who was treated with Pyostacine (dosage: NA, start time:
Jun 22, 2010), combined with:
  • Lasix
  • Ixprim
  • Lyrica
  • Lisinopril And Hydrochlorothiazide
  • Zanidip
and developed a serious reaction and side effect(s): Diarrhoea, Fall, Hypotension, Renal Failure Acute, Vomiting after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Pyostacine treatment in female patients, resulting in Diarrhoea side effect. The patient was hospitalized.
Pyostacine Side Effect Report#6248953-3
Leukocytoclastic Vasculitis
This report suggests a potential Pyostacine Leukocytoclastic Vasculitis side effect(s) that can have serious consequences. A 52-year-old male patient (weight: NA) from was diagnosed with the following symptoms/conditions: erysipelas and used Pyostacine (dosage: NA) starting
Jan 01, 2009. After starting Pyostacine the patient began experiencing various side effects, including: Leukocytoclastic VasculitisAdditional drugs used concurrently:
  • Torental
  • Tracleer
  • Tracleer
The patient was hospitalized. Although Pyostacine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Leukocytoclastic Vasculitis, may still occur.
Pyostacine Side Effect Report#6209987-8
Colitis, International Normalised Ratio Increased, Rectal Haemorrhage
This Colitis problem was reported by a consumer or non-health professional from . A 84-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Jan 07, 2009 this consumer started treatment with Pyostacine (dosage: NA). The following drugs were being taken at the same time:
  • Lovenox
  • Hydrocortisone /00028607/
  • Previscan /00789001/
  • Kardegic /00002703/
  • Clamoxyl /00249601/
  • Paracetamol
  • Topalgic
  • Bricanyl
When using Pyostacine, the patient experienced the following unwanted symptoms/side effects: Colitis, International Normalised Ratio Increased, Rectal HaemorrhageThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Colitis, may become evident only after a product is in use by the general population.
Pyostacine Side Effect Report#6165594-7
Erythema, Skin Exfoliation, Toxic Epidermal Necrolysis
This Erythema side effect was reported by a consumer or non-health professional from . A 80-year-old female patient (weight:NA) experienced the following symptoms/conditions: hyperthermia.The patient was prescribed Pyostacine (drug dosage: NA), which was initiated on
Jan 26, 2009. Concurrently used drugs:
  • Lasilix /00032601/
  • Cortancyl
  • Norset
  • Prazepam
  • Lepticur
  • Celectol
  • Laxatives
  • Previscan /00789001/
.After starting to take Pyostacine the consumer reported adverse symptoms, such as: Erythema, Skin Exfoliation, Toxic Epidermal NecrolysisThese side effects may potentially be related to Pyostacine. The patient was hospitalized.
Pyostacine Side Effect Report#6072075-8
Colitis, International Normalised Ratio Increased, Rectal Haemorrhage
This is a report of a 84-year-old female patient (weight: NA) from , suffering from the following health symptoms/conditions: NA, who was treated with Pyostacine (dosage: NA, start time:
Jan 07, 2009), combined with:
  • Lovenox
  • Hydrocortisone /00028607/
  • Previscan /00789001/
  • Kardegic /00002703/
  • Clamoxyl /00249601/
  • Paracetamol
  • Topalgic
  • Bricanyl
and developed a serious reaction and side effect(s): Colitis, International Normalised Ratio Increased, Rectal Haemorrhage after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Pyostacine treatment in female patients, resulting in Colitis side effect. The patient was hospitalized.
Pyostacine Side Effect Report#5700620-8
Fall, Nausea
This report suggests a potential Pyostacine Fall side effect(s) that can have serious consequences. A 52-year-old female patient (weight: NA) from was diagnosed with the following symptoms/conditions: NA and used Pyostacine (dosage: NA) starting
Feb 04, 2008. After starting Pyostacine the patient began experiencing various side effects, including: Fall, NauseaAdditional drugs used concurrently:
  • Ketek
  • Flanid
The patient was hospitalized. Although Pyostacine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Fall, may still occur.
Pyostacine Side Effect Report#5641071-4
Condition Aggravated, Rash Pustular
This Condition Aggravated problem was reported by a consumer or non-health professional from . A 94-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Oct 04, 2007 this consumer started treatment with Pyostacine (dosage: NA). The following drugs were being taken at the same time:
  • Lasilix /00032601/
  • Lanzor
  • Cordarone
  • Kardegic /00002703/
  • Tiapridal /00435701/
  • Forlax
  • Noctran
  • Dermoval /00337102/
When using Pyostacine, the patient experienced the following unwanted symptoms/side effects: Condition Aggravated, Rash PustularThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Condition Aggravated, may become evident only after a product is in use by the general population.
Pyostacine Side Effect Report#5585627-6
Condition Aggravated, Rash Pustular
This Condition Aggravated side effect was reported by a consumer or non-health professional from . A 94-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Pyostacine (drug dosage: NA), which was initiated on
Oct 04, 2007. Concurrently used drugs:
  • Lasix
  • Lanzor
  • Cordarone
  • Kardegic /00002703/
  • Tiapridal /00435701/
  • Forlax
  • Noctran
  • Dermoval /00337102/
.After starting to take Pyostacine the consumer reported adverse symptoms, such as: Condition Aggravated, Rash PustularThese side effects may potentially be related to Pyostacine. The patient was hospitalized.
Pyostacine Side Effect Report#5472754-7
Asthenia, Eosinophilia, Face Oedema, Inflammation, Nephritis Interstitial, Odynophagia, Pruritus, Purpura
This is a report of a 71-year-old male patient (weight: NA) from , suffering from the following health symptoms/conditions: NA, who was treated with Pyostacine (dosage: NA, start time:
Jan 01, 2006), combined with:
  • Lovenox
  • Vancomycin
  • Josir
  • Gaviscon /01405501/
  • Rifadin
  • Oflocet /00731801/
  • Imovane
  • Topalgic
and developed a serious reaction and side effect(s): Asthenia, Eosinophilia, Face Oedema, Inflammation, Nephritis Interstitial, Odynophagia, Pruritus, Purpura after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Pyostacine treatment in male patients, resulting in Asthenia side effect. The patient was hospitalized.


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The appearance of Pyostacine on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.

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It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

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  • Log Form

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    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Pyostacine reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

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    Pyostacine Safety Alerts, Active Ingredients, Usage Information

    More About Pyostacine

    Side Effects reported to FDA: 40

    Pyostacine safety alerts: No

    Reported deaths: 1

    Reported hospitalizations: 29

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