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Hallucinations (1)
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Rasagiline Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Parkinson's Disease (8414719-9)
on May 23, 2012 Male from CHINA , weighting 178.6 lb, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline Mesylate. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: parkinson's disease. Rasagiline Mesylate dosage: N/A.
Associated medications used:
  • Sinemet (1st Dose)
  • Sinemet (3rd Dose)
  • Sinemet (1st Dose)
  • Entacapone (200 Milligram;)
  • Piribedil Sustained Release Tablets (150 Milligram;)
  • Madopar (1st Dose)
  • Sinemet (2nd Dose)
Patient was hospitalized.

Jealous Delusion, Marital Problem (8343681-2)
Patient was taking Rasagiline. Patient felt the following Rasagiline side effects: jealous delusion, marital problem on May 02, 2012 from SPAIN Additional patient health information: Male , 61 years of age, was diagnosed with
  • parkinson's disease
and. Rasagiline dosage: 1 Mg.
Multiple prescriptions taken:
  • Pramipexole Dihydrochloride (2.1 Mg)


Laryngeal Cancer (8164413-7)
Adverse event was reported on Feb 13, 2012 by a Male taking Rasagiline Mesylate (Dosage: 1 Milligram; Ol- Adagio Fu, 1mg/day) was diagnosed with
  • parkinson's disease
and. Location: ARGENTINA , weighting 165.3 lb, After Rasagiline was administered, patient encountered several Rasagiline side effects: laryngeal cancer.
Multiple concurrent drugs taken:
  • Carbidopa + Levodopa (100/25 Bid)


Serotonin Syndrome, Neuroleptic Malignant Syndrome (8164107-8)
on Feb 07, 2012 Male from DENMARK , 81 years of age, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: serotonin syndrome, neuroleptic malignant syndrome. Rasagiline dosage: N/A.
Associated medications used:
  • Finasteride (finasteride)(finasteride)
  • Omeprazole
  • Stalevo (stalevo) (stalevo)
  • Dalteparin (dalteparin) (dalteparin)
  • Calcium W/colecalciferol(calcium, Colecalciferol)(calcium, Colecalcife
  • Alendronic Acid (alendronic Acid)(alendronic Acid)
  • Citalopram Hydrobromide
  • Midodrine (midodrine) (midodrine)
Patient was hospitalized.


Quality Of Life Decreased, Confusional State, Cognitive Disorder, Activities Of Daily Living Impaired, Apathy (8126115-2)
on Jan 31, 2012 Male from BRAZIL , 72 years of age, was treated with Rasagiline. Patient felt the following Rasagiline side effects: quality of life decreased, confusional state, cognitive disorder, activities of daily living impaired, apathy. Rasagiline dosage: N/A.
Multiple prescriptions taken:
  • Domperidone (30 Mg/daily)
  • Benserazide Hydrochloride W/levodopa (100/25 Mg)
  • Entacapone (200 Mg/day)
  • Enablex (7.5 Mg, Unk)
  • Lactulose
  • Rivastigmine (2 Mg, Tid)
  • Amantadine Hcl (300 Mg/day)
  • Tolcapone (300 Mg/day)


Squamous Cell Carcinoma (8105727-6)
Patient was taking Rasagiline Mesylate. After Rasagiline was administered, patient encountered several Rasagiline side effects: squamous cell carcinoma on Jan 26, 2012 from ARGENTINA Additional patient health information: Male , weighting 165.3 lb, was diagnosed with
  • parkinson's disease
and. Rasagiline Mesylate dosage: 1 Milligram; Ol- Adagio Fu, 1mg/day.

Squamous Cell Carcinoma (8094859-7)
Adverse event was reported on Jan 24, 2012 by a Male taking Rasagiline Mesylate (Dosage: 1 Milligram; Ol- Adagio Fu, 1mg/day) was diagnosed with
  • parkinson's disease
and. Location: ARGENTINA , weighting 165.3 lb, Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: squamous cell carcinoma.
Associated medications used:
  • Carbidopa + Levodopa (100/25 Bid)


Hyperpyrexia, Muscle Rigidity, Neuroleptic Malignant Syndrome, Hypertonia, Serotonin Syndrome, Hyperhidrosis, Blood Creatine Phosphokinase Increased (7788856-6)
on Sep 13, 2011 Male from , 81 years of age, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline. Patient felt the following Rasagiline side effects: hyperpyrexia, muscle rigidity, neuroleptic malignant syndrome, hypertonia, serotonin syndrome, hyperhidrosis, blood creatine phosphokinase increased. Rasagiline dosage: 1 Mg (1 Mg,1 In 1 D),oral.
Multiple prescriptions taken:
  • Midodrine Hydrochloride
  • Piperacillin And Tazobactam (pip/tazo)
  • Stalevo 100
  • Alendronate Sodium
  • Finasteride
  • Citalopram Hydrobromide (10 Mg (10 Mg,1 In 1 D),oral)
  • Calcium And Colecalciferol (lekovit Ca)
  • Omeprazole
Patient was hospitalized.

Aggression, Paranoia, Suicidal Ideation, Euphoric Mood, Excessive Exercise, Voyeurism, Panic Attack, Sudden Onset Of Sleep, Delusion (7652799-9)
on Jul 12, 2011 Male from , 65 years of age, weighting 189.6 lb, was treated with Rasagiline Mesylate (rasagiline). After Rasagiline was administered, patient encountered several Rasagiline side effects: aggression, paranoia, suicidal ideation, euphoric mood, excessive exercise, voyeurism, panic attack, sudden onset of sleep, delusion. Rasagiline Mesylate (rasagiline) dosage: N/A.
Multiple concurrent drugs taken:
  • Ropinirole (750 Micrograms, 3 In 1 D, Oral Use)
  • Requip Xl (36 Milligram, 1 In 1 D, Oral Use)
  • Co-careldopa (carbidopa, Levodopa) (carbidopa, Levodopa)
  • Sinemet (carbidopa, Carbidopa Monohydrate, Levodopa) (carbidopa, Carbi
Patient was hospitalized and became disabled.

Feeling Drunk, Tremor (7649625-0)
Patient was taking Rasagiline. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: feeling drunk, tremor on Jul 31, 2011 from UNITED STATES Additional patient health information: Male , weighting 229.3 lb, . Rasagiline dosage: 1 Mg, 1x/day.
Associated medications used:
  • Neurontin (300 Mg, 3x/day)
  • Neurontin
  • Dyazide (Unk)
  • Neurontin


Obsessive Thoughts, Aggression, Dementia, Obsessive-compulsive Disorder, Libido Increased, Impulse-control Disorder, Excessive Sexual Fantasies, Personality Change, Withdrawal Syndrome (7217988-6)
Adverse event was reported on Jan 07, 2011 by a Male taking Rasagiline Mesylate (Dosage: N/A) . Location: UNITED KINGDOM , 67 years of age, weighting 189.6 lb, Patient felt the following Rasagiline side effects: obsessive thoughts, aggression, dementia, obsessive-compulsive disorder, libido increased, impulse-control disorder, excessive sexual fantasies, personality change, withdrawal syndrome.
Multiple prescriptions taken:
  • Sinemet
  • Ropinirole
  • Requip Xl


Anaemia, Asthenia, Folate Deficiency, Gastritis Atrophic, Macrocytosis, Oedema Peripheral, Vitamin B12 Deficiency (7090200-7)
on Oct 29, 2010 Male from ARGENTINA , weighting 172.0 lb, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline Mesylate. After Rasagiline was administered, patient encountered several Rasagiline side effects: anaemia, asthenia, folate deficiency, gastritis atrophic, macrocytosis, oedema peripheral, vitamin b12 deficiency. Rasagiline Mesylate dosage: N/A. Patient was hospitalized.

Anaemia, Asthenia, Oedema Peripheral (7059940-X)
on Oct 14, 2010 Male from ARGENTINA , weighting 172.0 lb, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline Mesylate. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: anaemia, asthenia, oedema peripheral. Rasagiline Mesylate dosage: N/A. Patient was hospitalized.

Anaemia, Asthenia, Oedema Peripheral (7047866-7)
Patient was taking Rasagiline Mesylate. Patient felt the following Rasagiline side effects: anaemia, asthenia, oedema peripheral on Oct 06, 2010 from ARGENTINA Additional patient health information: Male , weighting 172.0 lb, was diagnosed with
  • parkinson's disease
and. Rasagiline Mesylate dosage: N/A. Patient was hospitalized.

Anaemia, Asthenia, Oedema Peripheral (7040282-3)
Adverse event was reported on Sep 29, 2010 by a Male taking Rasagiline Mesylate (Dosage: N/A) was diagnosed with
  • parkinson's disease
and. Location: ARGENTINA , weighting 172.0 lb, After Rasagiline was administered, patient encountered several Rasagiline side effects: anaemia, asthenia, oedema peripheral. Patient was hospitalized.

Convulsion, Hypersensitivity (6955964-9)
on Aug 26, 2010 Female from UNITED STATES , 42 years of age, weighting 178.4 lb, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline. Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: convulsion, hypersensitivity. Rasagiline dosage: 1mg Daily Po. Patient was hospitalized.

Tardive Dyskinesia (6425923-3)
on Nov 03, 2009 Male from UNITED STATES , 64 years of age, was treated with Rasagiline. Patient felt the following Rasagiline side effects: tardive dyskinesia. Rasagiline dosage: Po.

Confusional State, Hallucination, Visual (6397611-3)
Patient was taking Rasagiline. After Rasagiline was administered, patient encountered several Rasagiline side effects: confusional state, hallucination, visual on Sep 28, 2009 from SPAIN Additional patient health information: Female , 66 years of age, was diagnosed with
  • parkinson's disease
  • depression
and. Rasagiline dosage: 1 Mg/day.
Multiple concurrent drugs taken:
  • Escitalopram (10 Mg/day)
Patient was hospitalized.

Diarrhoea, Nausea, Vomiting (6030578-6)
Adverse event was reported on Jan 06, 2009 by a Male taking Rasagiline (Dosage: 1 Mg Every Day Po) was diagnosed with
  • parkinson's disease
and. Location: UNITED STATES , 63 years of age, weighting 170.7 lb, Directly after, patient experienced the unwanted or unexpected Rasagiline side effects: diarrhoea, nausea, vomiting.
Associated medications used:
  • Carbidopa And Levodopa (50/200 Mg Bid Po)


Blood Pressure Inadequately Controlled, Hypertension (6028832-7)
on Jan 05, 2009 Male from UNITED STATES , 79 years of age, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline. Patient felt the following Rasagiline side effects: blood pressure inadequately controlled, hypertension. Rasagiline dosage: 1 Mg Every Day Po.

Myocardial Infarction (6003124-0)
on Dec 08, 2008 Female from SOUTH AFRICA , weighting 152.1 lb, was diagnosed with
  • parkinson's disease
and was treated with Rasagiline Mesilate. After Rasagiline was administered, patient encountered several Rasagiline side effects: myocardial infarction. Rasagiline Mesilate dosage: N/A.
Multiple concurrent drugs taken:
  • Sinemet (100/25)
  • Bromocriptine
  • Amantadine Hcl
  • Metformin Hcl
  • Amlodipine
  • Enalapril Maleate


(5084837-4)
Patient was taking Rasagiline Mesylate. on Aug 01, 2006 from GERMANY Additional patient health information: Male , 80 years of age, . Rasagiline Mesylate dosage: 1 Milligram.
Associated medications used:
  • Carbidopa And Levodopa
  • Seroquel
  • Melperone Hydrochloride


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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Rasagiline Information

More About Rasagiline

Side Effects reported to FDA: 22. View Rasagiline Adverse Reports

Rasagiline safety alerts: No

Reported deaths: 1

Reported hospitalizations: 5

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