Rasburicase Side Effects summary

Total Rasburicase reports: 18. View

Rasburicase FDA safety alerts: No.

Reported deaths: 2

Reported hospitalizations: 5.

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Recently reported Rasburicase Side Effects


Common Rasburicase Side Effects
Dyspnoea 39%
Aspartate aminotransferase increased 17%
Bronchospasm 17%
Cardiac arrest  What is  Cardiac arrest                                                                                                                                                                                          17%
Confusional state 17%
Hyperthermia 17%
Hypotension 17%
Oxygen saturation decreased 17%
Platelet count decreased 17%
Acidosis 11%
Alanine aminotransferase increased 11%
Blood bilirubin increased 11%
Blood lactate dehydrogenase increased 11%
Blood methaemoglobin present 11%
Chills 11%
Cough 11%
Gastrointestinal haemorrhage 11%
Haematuria 11%
Haemolysis 11%
Hepatic failure 11%
Hepatotoxicity 11%
Hyperbilirubinaemia 11%
Hypoxia 11%
Liver function test abnormal 11%
Methaemoglobinaemia 11%
Pulmonary haemorrhage 11%
Alanine aminotransferase decreased 6%
Anaemia 6%
Anaphylactic reaction 6%
Anti-hbs antibody 6%
Anti-hbs antibody positive 6%
Ascites 6%
Blood creatinine increased 6%
Blood fibrinogen increased 6%
Blood ph increased 6%
Blood potassium decreased 6%
Blood pressure decreased 6%
Cholelithiasis 6%
Condition aggravated 6%
Cytomegalovirus antibody positive 6%
Feeling hot 6%
Gallbladder disorder 6%
Gamma-glutamyltransferase increased 6%
Glucose-6-phosphate dehydrogenase deficiency 6%
Haemoglobin decreased 6%
Hepatitis b  What is  Hepatitis b                                                                                                                                                                                             6%
Hyperkalaemia 6%
Infusion related reaction 6%
Loss of consciousness 6%
Muscle twitching 6%
No therapeutic response 6%
Obstructive airways disorder 6%
Po2 increased 6%
Refusal of treatment by relative 6%
Renal failure acute 6%
Syncope 6%
Tachypnoea 6%
Thrombocytopenia 6%
Tumour lysis syndrome 6%
Venous oxygen saturation decreased 6%
Ventricular tachycardia 6%

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Rasburicase Side Effects Report #5221745-X
Pharmacist from UNITED STATES reported Rasburicase side effect on Jan 25, 2007. Male patient, child 12 years of age, weighting 132.3 lb, was diagnosed with blood uric acid increased, tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: glucose-6-phosphate dehydrogenase deficiency, hypoxia, loss of consciousness, methaemoglobinaemia, no therapeutic response. Rasburicase dosage: 10.5MG ONCE IV. Patient recovered.



Rasburicase Side Effects Report #5427401-7
Rasburicase side effect was reported by a Pharmacist from UNITED STATES on Aug 24, 2007. Male patient, 40 years of age, weighting 185.0 lb, was diagnosed with tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: acidosis, blood methaemoglobin present, hypoxia. Rasburicase dosage: 15 MG DAILY IV ONCE. Patient recovered.



Rasburicase Side Effects Report #5875964-X
Pharmacist from UNITED STATES reported Rasburicase side effect on Sept 08, 2008. Female patient was diagnosed with blood uric acid increased and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: acidosis, cardiac arrest What is  cardiac arrest, hyperkalaemia, renal failure acute, ventricular tachycardia. Rasburicase dosage: unknown. Patient was hospitalized. Patient recovered.



Rasburicase Side Effects Report #6027214-1
Rasburicase side effect was reported by a Pharmacist from UNITED STATES on Dec 31, 2008. Male patient, weighting 130.0 lb, was diagnosed with tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: blood methaemoglobin present, blood ph increased, oxygen saturation decreased, tachypnoea, venous oxygen saturation decreased. Rasburicase dosage: 6 MG ONCE IV BOLUS. Patient was hospitalized. Patient recovered.




Rasburicase Side Effects Report #4565649-4
Pharmacist from reported Rasburicase side effect on Jan 25, 2005. Male patient, 58 years of age, weighting 229.3 lb, was diagnosed with blood uric acid increased, prophylaxis, tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: blood creatinine increased, dyspnoea, methaemoglobinaemia, oxygen saturation decreased, po2 increased, tumour lysis syndrome. Rasburicase dosage: 15MG Q DAY INTRAVENOUS. During the same period patient was treated with DOXORUBICIN, CISPLATIN, CYTARABINE, DEXAMETHASONE, ALLOPURINOL, DOCUSATE. Patient recovered.



Rasburicase Side Effects Report #4572201-3
Rasburicase side effect was reported by a Consumer or non-health professional from on Jan 03, 2005. Male patient, 55 years of age, weighting 171.3 lb, was diagnosed with hyperuricaemia, leukaemia, neoplasm malignant and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: haemolysis, hyperbilirubinaemia. Rasburicase dosage: 0.2 MG/KG QD - INTRAVENOUSNOS. During the same period patient was treated with CYTARABINE, IDARUBICIN, VALSARTAN, GRANISETRON, DEXAMETHASONE. Patient recovered.



Rasburicase Side Effects Report #4579890-8
Consumer or non-health professional from reported Rasburicase side effect on Jan 20, 2005. Male patient, 55 years of age, weighting 171.3 lb, was diagnosed with hyperuricaemia and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: anaemia, haemolysis, hyperbilirubinaemia, platelet count decreased. Rasburicase dosage: H0.2 MG/KG QD -INTRAVENOUS NOS. During the same period patient was treated with CYTARABINE, IDARUBICIN, VALSARTAN, GRANISETRON, DEXAMETHASONE. Patient recovered.



Rasburicase Side Effects Report #4582433-6
Rasburicase side effect was reported by a Physician from on Jan 21, 2005. Male patient, 44 years of age, weighting 207.2 lb, was diagnosed with hyperuricaemia, tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: alanine aminotransferase decreased, aspartate aminotransferase increased, blood fibrinogen increased, blood lactate dehydrogenase increased, confusional state, dyspnoea, gamma-glutamyltransferase increased, liver function test abnormal. Rasburicase dosage: 0.2 MG/KG QD - INTRAVENOUS NOS. During the same period patient was treated with ALLOPURINOL, CYTARABINE, MITOXANTRONE, PIPERACILLIN, GENTAMICIN, CEFTAZIDIME, VANCOMYCIN. Patient recovered.



Rasburicase Side Effects Report #4607178-5
Pharmacist from reported Rasburicase side effect on Mar 11, 2005. Male patient, 14 years of age, weighting 163.1 lb, was diagnosed with blood uric acid increased and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: anaphylactic reaction, obstructive airways disorder. Rasburicase dosage: 11 MG IV X 1. Patient recovered.




Rasburicase Side Effects Report #4610244-1
Rasburicase side effect was reported by a Physician from on Jan 21, 2005. Male patient, 44 years of age, weighting 207.2 lb, was diagnosed with hyperuricaemia, tumour lysis syndrome, acute leukaemia and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anti-hbs antibody, ascites, aspartate aminotransferase increased, blood bilirubin increased, confusional state, cough, cytomegalovirus antibody positive, dyspnoea. Rasburicase dosage: 0.2 MG/KG QD - INTRAVENOUS NOS. During the same period patient was treated with ALLOPURINOL, CYTARABINE, MITOXANTRONE, PIPERACILLIN, GENTAMICIN, CEFTAZIDIME, VANCOMYCIN. Patient recovered.



Rasburicase Side Effects Report #4619117-1
Health Professional from reported Rasburicase side effect on Apr 14, 2003. Female patient, weighting 121.3 lb, was treated with Rasburicase. After drug was administered, patient experienced the following side effects: bronchospasm, dyspnoea, hyperthermia, hypotension. Rasburicase dosage: 10.5 MG. During the same period patient was treated with LYSANXIA, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, RITUXIMAB. Patient was hospitalized. Patient recovered.



Rasburicase Side Effects Report #4624808-2
Rasburicase side effect was reported by a Health Professional from on Apr 14, 2003. Female patient, weighting 121.3 lb, was treated with Rasburicase. After drug was administered, patient experienced the following side effects: bronchospasm, chills, dyspnoea, hyperthermia, hypotension. Rasburicase dosage: 10.5 MG. During the same period patient was treated with LYSANXIA, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, RITUXIMAB. Patient was hospitalized. Patient recovered.



Rasburicase Side Effects Report #4639249-1
Health Professional from reported Rasburicase side effect on Oct 29, 2004. Female patient, weighting 126.3 lb, was diagnosed with hyperuricaemia and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, gallbladder disorder, gastrointestinal haemorrhage, haematuria, hepatic failure, hepatitis b What is  hepatitis b, hepatotoxicity, platelet count decreased, pulmonary haemorrhage. Rasburicase dosage: unknown. During the same period patient was treated with ALLOPURINOL, VANCOMYCIN, FORTAZ, NAFCILLIN, ACYCLOVIR, SPORANOX, CIPROFLOXACIN. Patient died on 11/16/2004.



Rasburicase Side Effects Report #4640183-1
Rasburicase side effect was reported by a Health Professional from on Apr 14, 2003. Female patient, 57 years of age, was diagnosed with hyperuricaemia, non-hodgkin's lymphoma and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: blood potassium decreased, bronchospasm, chills, dyspnoea, haemoglobin decreased, hyperthermia, hypotension. Rasburicase dosage: 10.5 MG INTRAVENOUS NOS. During the same period patient was treated with LYSANXIA, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, PREDNISONE, RITUXIMAB. Patient was hospitalized. Patient recovered.




Rasburicase Side Effects Report #4651407-9
Consumer or non-health professional from reported Rasburicase side effect on Apr 08, 2005. Female patient, 70 years of age, weighting 126.3 lb, was diagnosed with hyperuricaemia, leukaemia, lymphoma What is  lymphoma, tumour lysis syndrome and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: cardiac arrest What is  cardiac arrest, cholelithiasis, gastrointestinal haemorrhage, haematuria, hepatic failure, hepatotoxicity, platelet count decreased, pulmonary haemorrhage, refusal of treatment by relative. Rasburicase dosage: 0.2 MG/KG QD - INTRAVENOUS NOS. During the same period patient was treated with ALLOPURINOL, VANCOMYCIN, CEFTAZIDIME, NAFCILLIN, ACYCLOVIR. Patient died on 11/16/2004.



Rasburicase Side Effects Report #4835468-X
Rasburicase side effect was reported by a Pharmacist from UNITED STATES on Nov 22, 2005. Male patient, weighting 416.2 lb, was diagnosed with hyperuricaemia, stem cell transplant and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: blood pressure decreased, feeling hot, infusion related reaction, oxygen saturation decreased, syncope. Rasburicase dosage: 15 MG IV X 1 DOSE. During the same period patient was treated with LEVOFLOXACIN, FLUCONAZOLE, VALACYCLOVIR, PANTOPRAZOLE, GABAPENTIN, SERTRALINE, METOLAZONE. Patient recovered.



Rasburicase Side Effects Report #4903714-X
Health Professional from UNITED STATES reported Rasburicase side effect on Jan 21, 2005. Male patient, weighting 207.2 lb, was diagnosed with hyperuricaemia and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anti-hbs antibody positive, aspartate aminotransferase increased, blood lactate dehydrogenase increased, confusional state, cough, dyspnoea, liver function test abnormal, muscle twitching. Rasburicase dosage: unknown. During the same period patient was treated with ALLOPURINOL, CYTARABINE, MITOXANTRONE, ZOSYN, GENTAMICIN, FORTAZ, VANCOMYCIN, ACYCLOVIR. Patient recovered.



Rasburicase Side Effects Report #5029217-2
Rasburicase side effect was reported by a Pharmacist from UNITED STATES on June 16, 2006. Female patient, 46 years of age, weighting 171.1 lb, was diagnosed with blood uric acid increased and was treated with Rasburicase. After drug was administered, patient experienced the following side effects: blood bilirubin increased, condition aggravated, thrombocytopenia. Rasburicase dosage: 1.5MG DAILY X3 DAYS IV. Patient recovered.





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I took clavulin for 7 days at the beginning of Sept. On Oct. 3 I became itchy from head to toe. Bloo

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