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Itching (32)
Itching In Vagina (15)
Frozen Shoulder (8)
RED RASHESH AROUND ARMS AND MOUTH BURNING SENS (7)
Sewear Pain In Shoulder (6)
Vomiting (6)
Fever (4)
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Rifampicin Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 466 

Hepatic Failure, Blood Alkaline Phosphatase Increased, Agitation, Adverse Reaction, Alanine Aminotransferase Increased, Pseudolymphoma, Blood Bilirubin Increased, Prothrombin Time Prolonged (8333695-0)
on Apr 23, 2012 Female from UNITED KINGDOM , 32 years of age, was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: hepatic failure, blood alkaline phosphatase increased, agitation, adverse reaction, alanine aminotransferase increased, pseudolymphoma, blood bilirubin increased, prothrombin time prolonged. Rifampicin dosage: Dose Unit: 600 Mg.
Associated medications used:
  • Doxycycline
  • Clarithromycin
  • Acetaminophen (Dose As Used: 2-4 G For Several Weeks)
Patient was hospitalized.

Heart Rate Increased, Deep Vein Thrombosis, Groin Pain, Pulmonary Embolism, Hypotension, Chest Pain, Respiratory Rate Increased, Swelling, Dyspnoea (8333541-5)
Patient was taking Rifampicin. Patient felt the following Rifampicin side effects: heart rate increased, deep vein thrombosis, groin pain, pulmonary embolism, hypotension, chest pain, respiratory rate increased, swelling, dyspnoea on Apr 25, 2012 from INDIA Additional patient health information: Male , 22 years of age, was diagnosed with
  • pulmonary tuberculosis
and. Rifampicin dosage: N/A.
Multiple prescriptions taken:
  • Isoniazid
  • Ethambutol Hydrochloride
  • Pyrazinamide
Patient was hospitalized.

Groin Pain, Coagulation Time Shortened, Deep Vein Thrombosis, Antithrombin Iii Decreased, Bleeding Time Shortened, Swelling, Fibrin Degradation Products Increased (8333519-1)
Adverse event was reported on Apr 25, 2012 by a Male taking Rifampicin (Dosage: N/A) was diagnosed with
  • pleural effusion
and. Location: INDIA , 26 years of age, After Rifampicin was administered, patient encountered several Rifampicin side effects: groin pain, coagulation time shortened, deep vein thrombosis, antithrombin iii decreased, bleeding time shortened, swelling, fibrin degradation products increased.
Multiple concurrent drugs taken:
  • Isoniazid
  • Ethambutol Hydrochloride
  • Isoniazid
  • Pyrazinamide
  • Ethambutol Hydrochloride


Blister, Blood Bilirubin Increased, Hepatic Enzyme Increased, Rash, Porphyria Non-acute (8322844-6)
on Apr 24, 2012 Male from HONG KONG , 59 years of age, was diagnosed with
  • pulmonary tuberculosis
and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: blister, blood bilirubin increased, hepatic enzyme increased, rash, porphyria non-acute. Rifampicin dosage: 600 Mg, Three Times A Week.
Associated medications used:
  • Isoniazid (600 Mg, Three Times A Week)
  • Ethambutol Hydrochloride (1.5 G, Three Times A Week)
  • Ethambutol Hydrochloride (700 Mg, Daily)
  • Pyrazinamide (2 G, Three Times A Week)



Pyrexia, Hepatic Function Abnormal, Erythema (8322829-X)
on Apr 23, 2012 Male from JAPAN , 63 years of age, was treated with Rifampicin. Patient felt the following Rifampicin side effects: pyrexia, hepatic function abnormal, erythema. Rifampicin dosage: N/A.
Multiple prescriptions taken:
  • Isoniazid
  • Ethambutol Hydrochloride
  • Pyrazinamide
Patient was hospitalized.

Lichenoid Keratosis (8320994-1)
Patient was taking Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: lichenoid keratosis on Apr 24, 2012 from ITALY Additional patient health information: Male , 66 years of age, was diagnosed with
  • prophylaxis
  • psoriasis
and. Rifampicin dosage: N/A.
Multiple concurrent drugs taken:
  • Methotrexate
  • Folina
  • Ramipril
  • Furosemide
Patient was hospitalized.

Hepatic Failure, Confusional State, Haemoglobin Decreased, Agitation, Prothrombin Time Prolonged, Encephalopathy, Hodgkin's Disease, Pseudolymphoma (8315690-0)
Adverse event was reported on Apr 23, 2012 by a Female taking Rifampicin (Dosage: 600 Mg, Bid) was diagnosed with
  • animal scratch
and. Location: UNITED KINGDOM , 32 years of age, Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: hepatic failure, confusional state, haemoglobin decreased, agitation, prothrombin time prolonged, encephalopathy, hodgkin's disease, pseudolymphoma.
Associated medications used:
  • Clarithromycin
  • Doxycycline (Unk)
Patient was hospitalized.

Visual Acuity Reduced (8282806-4)
on Apr 02, 2012 Female from SOUTH AFRICA , weighting 85.10 lb, was diagnosed with
  • pulmonary tuberculosis
and was treated with Rifampicin. Patient felt the following Rifampicin side effects: visual acuity reduced. Rifampicin dosage: Unk.
Multiple prescriptions taken:
  • Isoniazid (Unk)
  • Moxifloxacin (Unk)
  • Pyrazinamide (Unk)


Abdominal Pain, Benign Salivary Gland Neoplasm (8280786-9)
on Mar 30, 2012 Male from KOREA, REPUBLIC OF , 60 years of age, was diagnosed with
  • latent tuberculosis
and was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: abdominal pain, benign salivary gland neoplasm. Rifampicin dosage: N/A.
Multiple concurrent drugs taken:
  • Humira
  • Sulfasalazine
  • Meloxicam
  • Humira
  • Meloxicam
  • Sulfasalazine


Unresponsive To Stimuli, Immobile, Eye Movement Disorder, Pulmonary Embolism (8266908-4)
Patient was taking Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: unresponsive to stimuli, immobile, eye movement disorder, pulmonary embolism on Apr 04, 2012 from UNITED STATES Additional patient health information: Male , weighting 237.0 lb, . Rifampicin dosage: N/A. Patient was hospitalized.

Porphyria Non-acute (8241591-2)
Adverse event was reported on Mar 22, 2012 by a Male taking Rifampicin (Dosage: 600 Mg, Unk) was diagnosed with
  • pulmonary tuberculosis
and. Location: HONG KONG , 59 years of age, Patient felt the following Rifampicin side effects: porphyria non-acute.
Multiple prescriptions taken:
  • Pyrazinamide (2 G, 3x/week)
  • Isoniazid (600 Mg, Unk)
  • Ethambutol (1.5 G, Unk)
Patient was hospitalized.

Pneumonia, Hydrocephalus (8235672-7)
on Mar 22, 2012 Female from JAPAN , 79 years of age, weighting 81.57 lb, was diagnosed with
  • atypical mycobacterial infection
  • prophylaxis
and was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: pneumonia, hydrocephalus. Rifampicin dosage: N/A.
Multiple concurrent drugs taken:
  • Sodium Gualenate Hydrate/l-glutamine (1g Daily)
  • Ethambutol Hydrochloride
  • Lactomin (2g Daily)
  • Clarithromycin


Haemolytic Anaemia, Eosinophilic Pneumonia (8232294-9)
on Mar 15, 2012 Male from UNITED KINGDOM , 76 years of age, weighting 198.4 lb, was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: haemolytic anaemia, eosinophilic pneumonia. Rifampicin dosage: Dose Unit:u.
Associated medications used:
  • Cubicin
Patient was hospitalized.

Interstitial Lung Disease (8225370-8)
Patient was taking Rifampicin. Patient felt the following Rifampicin side effects: interstitial lung disease on Mar 15, 2012 from JAPAN Additional patient health information: Male , 73 years of age, weighting 121.3 lb, was diagnosed with
  • postoperative wound infection
and. Rifampicin dosage: N/A.
Multiple prescriptions taken:
  • Cubicin
  • Tenormin (Divided Dose Frequency U)
  • Vancomycin
  • Amlodipine (Divided Dose Frequency U)
  • Candesartan Cilexetil (Divided Dose Frequency U)


Coordination Abnormal, Muscular Weakness, Confusional State, Dyspnoea (8220879-5)
Adverse event was reported on Mar 09, 2012 by a Female taking Rifampicin (Dosage: N/A) . Location: UNITED KINGDOM , 68 years of age, After Rifampicin was administered, patient encountered several Rifampicin side effects: coordination abnormal, muscular weakness, confusional state, dyspnoea.
Multiple concurrent drugs taken:
  • Ethambutol Hydrochloride
  • Antineoplastic Agents
  • Antineoplastic Agents
  • Antineoplastic Agents
Patient was hospitalized.

Haemophilus Infection, Mycobacterium Avium Complex Infection (8215030-1)
on Mar 08, 2012 Male from JAPAN , 51 years of age, was diagnosed with
  • mycobacterium avium complex infection
  • asthma
and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: haemophilus infection, mycobacterium avium complex infection. Rifampicin dosage: N/A.
Associated medications used:
  • Fluticasone Furoate (800 Mcg)
  • Prednisolone
  • Ethambutol Hydrochloride
  • Clarithromycin


Bronchitis Haemophilus, Mycobacterium Avium Complex Infection (8215029-5)
on Mar 08, 2012 Male from JAPAN , 66 years of age, was diagnosed with
  • mycobacterium avium complex infection
  • asthma
and was treated with Rifampicin. Patient felt the following Rifampicin side effects: bronchitis haemophilus, mycobacterium avium complex infection. Rifampicin dosage: N/A.
Multiple prescriptions taken:
  • Fluticasone Furoate (800 Mcg)
  • Prednisolone
  • Clarithromycin
  • Ethambutol Hydrochloride


Hypoaesthesia, Subarachnoid Haemorrhage, Neurogenic Bladder (8206567-X)
Patient was taking Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: hypoaesthesia, subarachnoid haemorrhage, neurogenic bladder on Mar 08, 2012 from JAPAN Additional patient health information: Male , 82 years of age, weighting 88.18 lb, . Rifampicin dosage: N/A.
Multiple concurrent drugs taken:
  • Ethambutol Hydrochloride
  • Astomin
  • Clarithromycin
  • Mucodyne
  • Mucosolvan


Haemoglobin Decreased, Pulmonary Tuberculosis, Toxic Epidermal Necrolysis (8204984-5)
Adverse event was reported on Feb 27, 2012 by a Male taking Rifampicin (Dosage: N/A) . Location: INDIA , 67 years of age, weighting 110.2 lb, Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: haemoglobin decreased, pulmonary tuberculosis, toxic epidermal necrolysis.
Associated medications used:
  • Pyrazinamide (;three Times A Week; 250mg;)
  • Isoniazid
  • Ethambutol Hydrochloride (;three Times A Week; 100 Mg;)
  • Ethambutol Hydrochloride (;three Times A Week; 100 Mg;)


Hyponatraemia, Altered State Of Consciousness, Diarrhoea, Adrenal Insufficiency, Vomiting (8202660-6)
on Mar 05, 2012 Female from JAPAN , 86 years of age, was diagnosed with
  • infection
and was treated with Rifampicin. Patient felt the following Rifampicin side effects: hyponatraemia, altered state of consciousness, diarrhoea, adrenal insufficiency, vomiting. Rifampicin dosage: N/A.
Multiple prescriptions taken:
  • Minocycline Hydrochloride
  • Sulfamethoxazole And Trimethoprim
  • Amikacin Sulfate
  • Vancomycin Hydrochloride


Prothrombin Time Prolonged, Disseminated Intravascular Coagulation, Functional Gastrointestinal Disorder, Cholangitis, Renal Failure Acute, Haemolysis, Hypersensitivity (8201792-6)
on Mar 02, 2012 Female from FRANCE , 48 years of age, was diagnosed with
  • tuberculosis
and was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: prothrombin time prolonged, disseminated intravascular coagulation, functional gastrointestinal disorder, cholangitis, renal failure acute, haemolysis, hypersensitivity. Rifampicin dosage: 600 Mg/day.
Multiple concurrent drugs taken:
  • Ethambutol (120 Mg/day)
Patient was hospitalized.

Liver Function Test Abnormal, Peripheral Ischaemia, Hepatitis Cholestatic, Jaundice (8189989-5)
Patient was taking Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: liver function test abnormal, peripheral ischaemia, hepatitis cholestatic, jaundice on Feb 24, 2012 from ARGENTINA Additional patient health information: Male , 75 years of age, was diagnosed with
  • infected skin ulcer
and. Rifampicin dosage: N/A.
Associated medications used:
  • Hmg Coa Reductase Inhibitors
Patient was hospitalized.

Hypocalcaemia, Hypokalaemia, Alkalosis, Blood Parathyroid Hormone Increased (8188803-1)
Adverse event was reported on Feb 21, 2012 by a Female taking Rifampicin (Dosage: N/A) . Location: TURKEY , 38 years of age, Patient felt the following Rifampicin side effects: hypocalcaemia, hypokalaemia, alkalosis, blood parathyroid hormone increased.
Multiple prescriptions taken:
  • Tetracycline Hydrochloride (X 4 Weeks Prior To Second Hospitalization)
  • Streptomycin
Patient was hospitalized.

Disseminated Intravascular Coagulation, Haemolysis (8180428-7)
on Feb 23, 2012 Female from POLAND , 53 years of age, was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: disseminated intravascular coagulation, haemolysis. Rifampicin dosage: 450 Mg, Unk. Patient was hospitalized.

Vitamin D Deficiency, Tetany, Hypocalcaemia, Alkalosis Hypokalaemic (8179946-7)
on Feb 20, 2012 Female from TURKEY , 38 years of age, was diagnosed with
  • brucellosis
and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: vitamin d deficiency, tetany, hypocalcaemia, alkalosis hypokalaemic. Rifampicin dosage: N/A.
Associated medications used:
  • Streptomycin
  • Tetracycline


Showing 1-25 of 466 

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Rifampicin Information

More About Rifampicin

Side Effects reported to FDA: 466. View Rifampicin Adverse Reports

Rifampicin safety alerts: No

Reported deaths: 97

Reported hospitalizations: 227

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