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Rifampicin Side Effects

Report Rifampicin Side Effects

If you experienced any harmful or unwanted effects of Rifampicin, please share your experience. This could help to raise awareness about Rifampicin side effects, identify uknown risks and inform health professionals and patients taking Rifampicin.

Examples: headache, dizziness


The most commonly reported Rifampicin side effects are:
Itching (35 reports)
Itching In Vagina (15 reports)
Frozen Shoulder (8 reports)
RED RASHESH AROUND ARMS AND MOUTH BURNING SENS (8 reports)
Sewear Pain In Shoulder (6 reports)
Vomiting (6 reports)
Fever (4 reports)
Frozen Shoulder, Sewear Pain In Shoulder (4 reports)
I Had Fever (3 reports)

If you have experienced a side effect listed above, you can check a box to report it.


To view a complete list of submitted side effects, please follow the link Rifampicin side effects . You can also compare Rifampicin side effects or view FDA reports.

Rifampicin Side Effects reported to FDA

The following Rifampicin reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
The FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Rifampicin on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has identified a causal relationship between the drug and the listed risk.

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Adrenocortical Insufficiency Acute, Postpartum Hypopituitarism
on Jan 02, 2014 Female from IN , 46 years of age, was diagnosed with and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: adrenocortical insufficiency acute, postpartum hypopituitarism. Rifampicin dosage: Unk.
Associated medications used:

Haemorrhage Intracranial, Hemiparesis, Convulsion, Speech Disorder, Somnolence, Musculoskeletal Stiffness, Meningism, Loss Of Consciousness, Altered State Of Consciousness
Patient was taking Rifampicin. Patient felt the following Rifampicin side effects: haemorrhage intracranial, hemiparesis, convulsion, speech disorder, somnolence, musculoskeletal stiffness, meningism, loss of consciousness, altered state of consciousness on Dec 26, 2013 from TR Additional patient health information: Female , 18 years of age, was diagnosed with and. Rifampicin dosage: 600 Mg, Unk.
Multiple prescriptions taken: Patient was hospitalized.

Epistaxis, Thrombocytopenia, Ecchymosis, Petechiae
Adverse event was reported on Dec 26, 2013 by a Female taking Rifampicin (Dosage: 600 Mg, Unk) was diagnosed with and. Location: TR , 35 years of age, After Rifampicin was administered, patient encountered several Rifampicin side effects: epistaxis, thrombocytopenia, ecchymosis, petechiae.
Multiple concurrent drugs taken: Patient was hospitalized.

Hepatic Failure, Ascites, Abdominal Pain, Abdominal Distension, Fatigue, Jaundice, Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, Gamma-glutamyltransferase Increased
on Dec 19, 2013 Female from TR , 47 years of age, was diagnosed with and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: hepatic failure, ascites, abdominal pain, abdominal distension, fatigue, jaundice, aspartate aminotransferase increased, alanine aminotransferase increased, gamma-glutamyltransferase increased. Rifampicin dosage: N/A.
Associated medications used: Patient was hospitalized.


Angioedema, Pruritus, Lip Swelling, Eyelid Oedema
on Dec 11, 2013 Female from US , 62 years of age, was diagnosed with and was treated with Rifampicin. Patient felt the following Rifampicin side effects: angioedema, pruritus, lip swelling, eyelid oedema. Rifampicin dosage: N/A.
Multiple prescriptions taken:
  • Metoprolol
  • Atorvastatin
  • Calcium
  • Vitamin D
  • Multivitamins
Patient was hospitalized.

Liver Injury, Tubulointerstitial Nephritis, Renal Failure Acute, Anaemia, Blood Creatinine Increased, Pyrexia, Chills
Patient was taking Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: liver injury, tubulointerstitial nephritis, renal failure acute, anaemia, blood creatinine increased, pyrexia, chills on Dec 06, 2013 from JP Additional patient health information: Male , 47 years of age, was diagnosed with and. Rifampicin dosage: 450 Mg Daily.
Multiple concurrent drugs taken:
  • Isoniazid (300 Mg, Unk)
  • Ethambutol (750 Mg, Unk)
  • Ethambutol (500 Mg, Unk)
  • Pyrazinamide (1.2 G, Unk)
  • Pyrazinamide (1 G, Unk)
Patient was hospitalized.

Hepatitis Fulminant
Adverse event was reported on Dec 05, 2013 by a Female taking Rifampicin Sandoz (Dosage: 450 Mg, Unk) was diagnosed with and. Location: JP , 71 years of age, weighting 101.4 lb, Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: hepatitis fulminant.
Associated medications used:
  • Iscotin (300 Mg, Unk)
  • Pyramide (1.2 G, Unk)
  • Amlodipine Besilate
  • Ebutol (750 Mg, Unk)
  • Pyridoxal (20 Mg, Unk)
  • Celecox
  • Gamofa
  • Diovan


Eosinophilic Pneumonia Acute, Dyspnoea, Pyrexia, Hypoxia, Cough
on Dec 05, 2013 Male from GB , 73 years of age, was treated with Rifampicin. Patient felt the following Rifampicin side effects: eosinophilic pneumonia acute, dyspnoea, pyrexia, hypoxia, cough. Rifampicin dosage: N/A.
Multiple prescriptions taken:

Renal Failure Acute, Transplant Dysfunction, Hyperuricaemia
on Dec 09, 2013 Male from TN , 38 years of age, was diagnosed with and was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: renal failure acute, transplant dysfunction, hyperuricaemia. Rifampicin dosage: Unk.
Multiple concurrent drugs taken:
  • Isoniazid (Unk)
  • Ethambutol (Unk)
  • Pyrazinamide (Unk)
  • Mycophenolate Mofetil (Unk)


Renal Failure Acute, Transplant Dysfunction
Patient was taking Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: renal failure acute, transplant dysfunction on Dec 02, 2013 from TN Additional patient health information: Male , 42 years of age, was diagnosed with and. Rifampicin dosage: Unk.
Associated medications used:
  • Isoniazid (Unk)
  • Ethambutol (Unk)
  • Pyrazinamide (Unk)
  • Azathioprine (Unk)
  • Antilymphocyte Serum (Unk)


Renal Failure Acute, Transplant Dysfunction
Adverse event was reported on Dec 02, 2013 by a Male taking Rifampicin (Dosage: Unk) was diagnosed with and. Location: TN , 60 years of age, Patient felt the following Rifampicin side effects: renal failure acute, transplant dysfunction.
Multiple prescriptions taken:
  • Isoniazid (Unk)
  • Ethambutol (Unk)
  • Pyrazinamide (Unk)
  • Mycophenolate Mofetil (Unk)


Transplant Dysfunction
on Dec 02, 2013 Male from TN , 39 years of age, was diagnosed with and was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: transplant dysfunction. Rifampicin dosage: Unk.
Multiple concurrent drugs taken:
  • Isoniazid (Unk)
  • Ethambutol (Unk)
  • Pyrazinamide (Unk)
  • Azathioprine (Unk)
  • Antilymphocyte Serum (Unk)


Renal Failure Acute, Complications Of Transplanted Kidney
on Dec 02, 2013 Female from TN , 14 years of age, was diagnosed with and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: renal failure acute, complications of transplanted kidney. Rifampicin dosage: Unk.
Associated medications used:
  • Isoniazid (Unk)
  • Ethambutol (Unk)
  • Pyrazinamide (Unk)
  • Mycophenolate Mofetil (Unk)
  • Antilymphocyte Serum (Unk)


Renal Failure Acute, Transplant Dysfunction
Patient was taking Rifampicin. Patient felt the following Rifampicin side effects: renal failure acute, transplant dysfunction on Dec 02, 2013 from TN Additional patient health information: Male , 37 years of age, was diagnosed with and. Rifampicin dosage: Unk.
Multiple prescriptions taken:
  • Isoniazid (Unk)
  • Ethambutol (Unk)
  • Pyrazinamide (Unk)
  • Tacrolimus (Unk)
  • Mycophenolate Mofetil (Unk)
  • Antilymphocyte Serum (Unk)


Transplant Dysfunction
Adverse event was reported on Dec 02, 2013 by a Male taking Rifampicin (Dosage: Unk) was diagnosed with and. Location: TN , 27 years of age, After Rifampicin was administered, patient encountered several Rifampicin side effects: transplant dysfunction.
Multiple concurrent drugs taken:
  • Isoniazid (Unk)
  • Ethambutol (Unk)
  • Pyrazinamide (Unk)
  • Azathioprine (Unk)
  • Antilymphocyte Serum (Unk)


Embolism, Cardiac Valve Vegetation, Staphylococcal Bacteraemia, No Therapeutic Response
on Mar 25, 2014 Male from GB , 40 years of age, was diagnosed with and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: embolism, cardiac valve vegetation, staphylococcal bacteraemia, no therapeutic response. Rifampicin dosage: N/A.
Associated medications used:

Liver Injury
on Nov 19, 2013 Male from FR , 74 years of age, was treated with Rifampicin. Patient felt the following Rifampicin side effects: liver injury. Rifampicin dosage: N/A.
Multiple prescriptions taken:
  • Cordarone
  • Lovenox (Strngth: 6000iu)
  • Kardegic
  • Vancomycine
  • Lasilix (Strength: 40mg)
  • Tahor (Strength: 10mg)
  • Bisoprolol (Strength: 10mg)
  • Eupantol (Strength: 20mg)


Cardiac Failure, Platelet Count Decreased, Mediastinal Abscess, Body Temperature Increased
Patient was taking Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: cardiac failure, platelet count decreased, mediastinal abscess, body temperature increased on Nov 18, 2013 from JP Additional patient health information: Male , 54 years of age, was diagnosed with and. Rifampicin dosage: N/A.
Multiple concurrent drugs taken: Patient was hospitalized.

Melaena, Abdominal Pain
Adverse event was reported on Nov 27, 2013 by a Female taking Rifampicin Sandoz (Dosage: 450 Mg, Daily) was diagnosed with and. Location: JP , 26 years of age, Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: melaena, abdominal pain.
Associated medications used:
  • Esanbutol (750 Mg, Daily)
  • Iscotin (400 Mg, Unk)
  • Pydoxal (20 Mg, Tid)


Acute Prerenal Failure, Adrenocortical Insufficiency Acute, Malaise, Depressed Level Of Consciousness, Nausea, Vomiting, Blood Pressure Decreased, Hyponatraemia, Dry Skin
on Nov 12, 2013 Female from TR , 44 years of age, was diagnosed with and was treated with Rifampicin. Patient felt the following Rifampicin side effects: acute prerenal failure, adrenocortical insufficiency acute, malaise, depressed level of consciousness, nausea, vomiting, blood pressure decreased, hyponatraemia, dry skin. Rifampicin dosage: N/A. Patient was hospitalized.

Paraplegia
on Nov 18, 2013 Female from GR , 81 years of age, was diagnosed with and was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: paraplegia. Rifampicin dosage: N/A.
Multiple concurrent drugs taken: Patient was hospitalized and became disabled.

Adrenocortical Insufficiency Acute, Malaise, Nausea, Vomiting, Depressed Level Of Consciousness, Blood Pressure Decreased, Heart Rate Increased, Body Temperature Increased, Mucosal Discolouration
Patient was taking Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: adrenocortical insufficiency acute, malaise, nausea, vomiting, depressed level of consciousness, blood pressure decreased, heart rate increased, body temperature increased, mucosal discolouration on Nov 20, 2013 from TR Additional patient health information: Female , 44 years of age, was diagnosed with and. Rifampicin dosage: N/A.
Associated medications used: Patient was hospitalized.

Encephalopathy, Cholecystitis, Hepatitis Cholestatic, Liver Function Test Abnormal, Nausea, Vomiting, Jaundice
Adverse event was reported on Nov 06, 2013 by a Male taking Rifampicin (Dosage: 300 Mg, Bid) was diagnosed with and. Location: GB , 25 years of age, weighting 155.9 lb, Patient felt the following Rifampicin side effects: encephalopathy, cholecystitis, hepatitis cholestatic, liver function test abnormal, nausea, vomiting, jaundice.
Multiple prescriptions taken: Patient was hospitalized.

Adrenocortical Insufficiency Acute
on Nov 06, 2013 Female from TR , 44 years of age, was diagnosed with and was treated with Rifampicin. After Rifampicin was administered, patient encountered several Rifampicin side effects: adrenocortical insufficiency acute. Rifampicin dosage: Unk.
Multiple concurrent drugs taken:
  • Isoniazide (Unk)
  • Pyrazinamide (Unk)
  • Ethambutol (Unk)
Patient was hospitalized.

Cardiomyopathy, Overdose, Electrocardiogram Abnormal, Troponin I Increased, Blood Creatine Phosphokinase Increased, Systolic Dysfunction, Ejection Fraction Decreased, Arrhythmia, Cardiogenic Shock
on Oct 31, 2013 Male from PL , 19 years of age, was diagnosed with and was treated with Rifampicin. Directly after, patient experienced the unwanted or unexpected Rifampicin side effects: cardiomyopathy, overdose, electrocardiogram abnormal, troponin i increased, blood creatine phosphokinase increased, systolic dysfunction, ejection fraction decreased, arrhythmia, cardiogenic shock. Rifampicin dosage: N/A.
Associated medications used: Patient was hospitalized.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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Safety Alerts, Active Ingredients, Usage Information

More About Rifampicin

Side Effects reported to FDA: 674

Rifampicin safety alerts: No

Reported deaths: 134

Reported hospitalizations: 323

Latest Rifampicin clinical trials