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Ringers Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Neonatal Respiratory Distress Syndrome, Premature Baby, Maternal Exposure During Pregnancy (7729707-5)
on Aug 29, 2011 Patient from AUSTRIA , weighting 4.41 lb, was diagnosed with
  • maternal exposure during pregnancy
and was treated with Ringers Injection In Plastic Container. Directly after, patient experienced the unwanted or unexpected Ringers side effects: neonatal respiratory distress syndrome, premature baby, maternal exposure during pregnancy. Ringers Injection In Plastic Container dosage: N/A.
Associated medications used:
  • Succinylcholine Chloride
  • Fentanyl Citrate
  • Thiopental Sodium (teva)


Arthralgia, Mobility Decreased, Condition Aggravated, Dysphagia, Muscle Rigidity, Pain In Extremity, Myotonia (7368593-2)
Patient was taking Ringers Acetate. Patient felt the following Ringers side effects: arthralgia, mobility decreased, condition aggravated, dysphagia, muscle rigidity, pain in extremity, myotonia on Mar 01, 2011 from JAPAN Additional patient health information: Female , 24 years of age, weighting 134.5 lb, . Ringers Acetate dosage: N/A.
Multiple prescriptions taken:
  • Oxytocin (5 Iu, Intravenous)
  • Methylergometrine Maleate (methylergometrine Maleate) (0.2 Mg, Intravenous)
  • Acetazolamide
Patient was hospitalized.

Blood Pressure Increased, Chills, Pyrexia (5664731-8)
Adverse event was reported on Mar 03, 2008 by a Male taking Ringers Injection In Plastic Container (Dosage: N/A) was diagnosed with
  • hypokalaemia
and. Location: POLAND , 68 years of age, weighting 198.4 lb, After Ringers was administered, patient encountered several Ringers side effects: blood pressure increased, chills, pyrexia.
Multiple concurrent drugs taken:
  • Potassium Chloride


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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Ringers Information

Alternative RINGERS Names:DEXTROSE, SODIUM CH

Active Ingredient: CALCIUM C

More About Ringers

Side Effects reported to FDA: 3. View Ringers Adverse Reports

Ringers safety alerts: 2013

Reported hospitalizations: 1

Lactated Ringers and 5 Percent Dextrose Injection, USP, 1000 ML, Flexible Containers: Recall - Due to Non-Sterility

[Posted 01/28/2013]

AUDIENCE: Pharmacy, Patient, Health Professional

ISSUE: Hospira, Inc. is initiating a voluntary nationwide user-level recall of one lot of Lactated Ringers and 5% Dextrose Injection, USP, 1000 mL, Flexible Container, NDC 0409-7929-09. This action is due to one confirmed customer report where a spore-like structured particulate, consistent with mold, was noted in the solution. Hospira has not received reports of any adverse events associated with this issue for this lot, and has not identified any quality issues with retention samples for this lot. If contaminated solution is used on a patient, this may cause thrombosis, phlebitis, bacteremia, sepsis, septic shock and/or endocarditis, or result in a fatal infection in a broad array of patients.

BACKGROUND: The product is used as a source of water, electrolytes and calories or as an alkalizing agent and is packaged in a 1000 mL flexible container, lot number 05-019-JT, with an expiration date of May 1, 2013. The affected lot was distributed nationwide between June 2011 and January 2012 to wholesalers/distributors, hospitals and pharmacies.

RECOMMENDATION: Anyone with an existing inventory should stop use and distribution, quarantine the product immediately, and call Stericycle at 1-888-965-5798 between the hours of 8am to 5pm EST, Monday through Friday, to arrange for the return of the product. Replacement product from other lots is available. For medical inquiries, please contact Hospira Medical Communications at 1-800-615-0187.

Healthcare professionals and patients are encouraged to report adverse events or side effects related to the use of these products to the FDA's MedWatch Safety Information and Adverse Event Reporting Program:

  • Complete and submit the report Online: www.fda.gov/MedWatch/report.htm
  • Download form or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178

[01/25/2013 - Firm Press Release - Hospira, Inc]

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