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Symlin Safety Reports
Total Symlin reports: 836.Symlin FDA safety alerts: No.
Reported deaths: 9 Reported hospitalizations: 56.
Take Symlin Side Effects Survey or Share Your Symlin Story.
Reported Symlin Side Effects: blood glucose increased, nausea, weight decreased, injection site pain, blood glucose decreased, decreased appetite, fatigue, injection site bruising, abdominal distension, incorrect dose administered, diarrhoea.
Symlin Usage.
Showing 1-50 of 836 Next >
Symlin Side Effects Report #5283438-2Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Oct 30, 2006. Male patient, 58 years of age, weighting 280.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: decreased appetite, dyspepsia, fatigue, nausea. SYMLIN dosage: unknown. During the same period patient was treated with METFORMIN, ACTOS, LANTUS, NOVOLOG, PRILOSEC. Patient recovered.
Symlin Side Effects Report #5283440-0
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 21, 2006. Male patient, 50 years of age, weighting 290.0 lb, was diagnosed with diabetes mellitus and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: alopecia, constipation, decreased appetite, nausea. SYMLIN dosage: unknown. During the same period patient was treated with NOVOLOG, HUMALOG, LANTUS, HUMULIN N, PROGRAF, CELLCEPT, PREDNISONE, NORVASC. Patient recovered.
Symlin Side Effects Report #5283441-2
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 22, 2006. Male patient, 60 years of age, weighting 224.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: decreased appetite, hypersomnia, sluggishness. SYMLIN dosage: unknown. During the same period patient was treated with HUMULIN, METFORMIN, AVANDIA. Patient recovered.
Symlin Side Effects Report #5283442-4
SYMLIN problem was reported by a Health Professional from UNITED STATES on Nov 28, 2006. Female patient, 28 years of age, was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: alopecia, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS. Patient recovered.
Symlin Side Effects Report #5283443-6
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 28, 2006. Female patient, 69 years of age, weighting 194.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site haemorrhage. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, NOVOLOG. Patient recovered.
Symlin Side Effects Report #5283444-8
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 29, 2006. Female patient, 51 years of age, weighting 220.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: abdominal distension, abdominal pain upper, liver function test abnormal. SYMLIN dosage: unknown. During the same period patient was treated with INSULIN, LASIX, ATENOLOL. Patient recovered.
Symlin Side Effects Report #5283445-X
Consumer or non-health professional from UNITED KINGDOM reported SYMLIN problem on Nov 29, 2006. Female patient, 73 years of age, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, decreased appetite. SYMLIN dosage: unknown. During the same period patient was treated with HUMALOG, LANTUS. Patient recovered.
Symlin Side Effects Report #5283473-4
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 11, 2006. Female patient, 63 years of age, weighting 249.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, decreased appetite. SYMLIN dosage: unknown. During the same period patient was treated with NOVOLOG, LANTUS, HUMULIN R. Patient recovered.
Symlin Side Effects Report #5283474-6
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 11, 2006. Male patient, 56 years of age, weighting 270.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: feeling cold, tremor. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, HUMALOG. Patient recovered.
Symlin Side Effects Report #5283477-1
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 14, 2006. Male patient, 70 years of age, weighting 220.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site pain. SYMLIN dosage: unknown. During the same period patient was treated with HUMALOG, LANTUS. Patient recovered.
Symlin Side Effects Report #5283479-5
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Sept 26, 2006. Female patient, 54 years of age, weighting 196.0 lb, was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: cough, cough decreased, glossodynia, rhinorrhoea. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, HUMALOG. Patient recovered.
Symlin Side Effects Report #5283481-3
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 13, 2006. Female patient was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site bruising. SYMLIN dosage: unknown. Patient recovered.
Symlin Side Effects Report #5283482-5
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Sept 25, 2006. Female patient was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased. SYMLIN dosage: unknown. During the same period patient was treated with NOVOLOG. Patient recovered.
Symlin Side Effects Report #5283484-9
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 14, 2006. Female patient, 53 years of age, was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: colitis microscopic, diarrhoea. SYMLIN dosage: unknown. Patient recovered.
Symlin Side Effects Report #5283485-0
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Sept 28, 2006. Female patient, 50 years of age, weighting 173.0 lb, was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: hypersensitivity, hypersomnia, injection site pain, injection site rash, mental impairment, nausea. SYMLIN dosage: unknown. During the same period patient was treated with EPIDRA INSULIN, ZYRTEC. Patient recovered.
Symlin Side Effects Report #5283488-6
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 01, 2006. Male patient, 49 years of age, weighting 220.0 lb, was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: fatigue, hypoaesthesia oral, nausea. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS. Patient recovered.
Symlin Side Effects Report #5283489-8
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 15, 2006. Female patient was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: abdominal distension, fatigue, injection site bruising. SYMLIN dosage: unknown. During the same period patient was treated with INSULIN. Patient recovered.
Symlin Side Effects Report #5283491-6
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 29, 2006. Female patient, 58 years of age, was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site bruising, injection site pain. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, NOVOLOG. Patient recovered.
Symlin Side Effects Report #5283501-6
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 15, 2006. Female patient, 57 years of age, weighting 203.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea, dizziness, nausea. SYMLIN dosage: unknown. During the same period patient was treated with HUMALOG, LANTUS. Patient recovered.
Symlin Side Effects Report #5283505-3
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 15, 2006. Male patient was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: fatigue, injection site bruising. SYMLIN dosage: unknown. Patient recovered.
Symlin Side Effects Report #5283520-X
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Oct 01, 2006. Female patient, 71 years of age, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site erythema, injection site pruritus, nausea. SYMLIN dosage: unknown. Patient recovered.
Symlin Side Effects Report #5283523-5
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 01, 2006. Female patient, 47 years of age, weighting 176.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: abdominal discomfort, asthenia, blood iron decreased, full blood count decreased, sluggishness, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, HUMALOG. Patient recovered.
Symlin Side Effects Report #5283524-7
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 15, 2006. Female patient was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: fatigue, injection site bruising. SYMLIN dosage: unknown. Patient recovered.
Symlin Side Effects Report #5283526-0
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 29, 2006. Male patient, 62 years of age, weighting 285.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, blood glucose decreased, blood glucose increased, decreased appetite, nausea, somnolence, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with HUMULIN, ACTOS. Patient recovered.
Symlin Side Effects Report #5283528-4
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Sept 29, 2006. Male patient, 62 years of age, weighting 420.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site haemorrhage, injection site pain, injection site urticaria, weight decreased. SYMLIN dosage: unknown. Patient recovered.
Symlin Side Effects Report #5283529-6
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 16, 2006. Male patient, 65 years of age, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: abdominal distension, blood glucose increased, eructation, flatulence, nausea, vomiting, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with HUMALOG. Patient recovered.
Symlin Side Effects Report #5283531-4
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Sept 30, 2006. Male patient, 66 years of age, weighting 244.5 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose decreased, blood glucose increased, constipation, injection site erythema, injection site pain, weight increased. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, NOVOLOG, BYETTA. Patient recovered.
Symlin Side Effects Report #5283534-X
SYMLIN problem was reported by a Pharmacist from UNITED STATES on Oct 16, 2006. Male patient, 51 years of age, weighting 197.0 lb, was diagnosed with diabetes mellitus and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: breath alcohol test positive. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, NOVOLOG. Patient recovered.
Symlin Side Effects Report #5283536-3
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Oct 16, 2006. Female patient, 50 years of age, weighting 200.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose decreased, decreased appetite, headache, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with AMARYL, ACTOS, AXERT. Patient recovered.
Symlin Side Effects Report #5283537-5
SYMLIN problem was reported by a Health Professional from UNITED STATES on Nov 06, 2006. Female patient, 21 years of age, was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: diarrhoea. SYMLIN dosage: unknown. During the same period patient was treated with NOVOLOG PEN, LANTUS. Patient recovered.
Symlin Side Effects Report #5283540-5
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Oct 18, 2006. Female patient, 57 years of age, weighting 165.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, feeling abnormal, nausea. SYMLIN dosage: unknown. During the same period patient was treated with BYETTA, NOVOLOG, NOVOLIN N. Patient recovered.
Symlin Side Effects Report #5283541-7
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 06, 2006. Male patient, 72 years of age, weighting 370.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site bruising, injection site pain. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, ASPIRIN. Patient recovered.
Symlin Side Effects Report #5283545-4
Health Professional from UNITED STATES reported SYMLIN problem on Oct 19, 2006. Male patient, 51 years of age, weighting 249.0 lb, was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: anorexia, decreased appetite, food craving, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with HUMAGLOG, LANTUS. Patient recovered.
Symlin Side Effects Report #5283549-1
SYMLIN problem was reported by a Health Professional from UNITED STATES on Nov 07, 2006. Male patient was diagnosed with diabetes mellitus and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: condition aggravated, muscle spasms. SYMLIN dosage: unknown. During the same period patient was treated with INSULIN. Patient recovered.
Symlin Side Effects Report #5283550-8
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Oct 19, 2006. Female patient, 75 years of age, weighting 143.0 lb, was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, diarrhoea, early satiety, fatigue, nausea, thirst. SYMLIN dosage: unknown. During the same period patient was treated with HUMALOG. Patient recovered.
Symlin Side Effects Report #5283554-5
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 07, 2006. Female patient, 44 years of age, was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased. SYMLIN dosage: unknown. During the same period patient was treated with HUMALOG. Patient recovered.
Symlin Side Effects Report #5283555-7
Physician from UNITED STATES reported SYMLIN problem on Oct 19, 2006. Female patient, 59 years of age, weighting 290.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, dry throat, increased upper airway secretion, sinus congestion, tremor, weight fluctuation. SYMLIN dosage: unknown. During the same period patient was treated with HUMULIN. Patient recovered.
Symlin Side Effects Report #5283558-2
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 29, 2006. Female patient, 66 years of age, weighting 153.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: increased appetite, weight increased. SYMLIN dosage: unknown. During the same period patient was treated with AVANDIA. Patient recovered.
Symlin Side Effects Report #5283561-2
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 08, 2006. Female patient, 60 years of age, weighting 213.5 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: decreased appetite. SYMLIN dosage: unknown. During the same period patient was treated with AVANDAMET. Patient recovered.
Symlin Side Effects Report #5283562-4
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 19, 2006. Male patient, 73 years of age, weighting 244.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: decreased appetite, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS. Patient recovered.
Symlin Side Effects Report #5283564-8
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Oct 19, 2006. Female patient, 65 years of age, weighting 180.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site pain, weight increased. SYMLIN dosage: unknown. During the same period patient was treated with LEVEMIR, LANTUS, LOTREL, SOTALOL HYDROCHLORIDE, HUMALOG. Patient recovered.
Symlin Side Effects Report #5283572-7
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 20, 2006. Female patient, 62 years of age, weighting 188.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site pain. SYMLIN dosage: unknown. During the same period patient was treated with METFORMIN, AMARYL, NOVO FLEXPEN. Patient recovered.
Symlin Side Effects Report #5283578-8
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 08, 2006. Female patient, 68 years of age, weighting 220.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: alopecia, condition aggravated. SYMLIN dosage: unknown. During the same period patient was treated with NOVOLOG, LANTUS. Patient recovered.
Symlin Side Effects Report #5283579-X
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 09, 2006. Male patient was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: injection site pain. SYMLIN dosage: unknown. Patient recovered.
Symlin Side Effects Report #5283589-2
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Nov 09, 2006. Female patient, 65 years of age, weighting 139.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: decreased appetite, energy increased. SYMLIN dosage: unknown. During the same period patient was treated with NOVOLOG, LANTUS. Patient recovered.
Symlin Side Effects Report #5283590-9
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 02, 2006. Female patient, 57 years of age, was diagnosed with diabetes mellitus insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased. SYMLIN dosage: unknown. During the same period patient was treated with HUMULIN R. Patient recovered.
Symlin Side Effects Report #5283591-0
Health Professional from UNITED STATES reported SYMLIN problem on Oct 02, 2006. Female patient, 46 years of age, was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: dyspnoea, eye infection, fatigue, immunisation reaction, lymphadenopathy, malaise, oedema peripheral, pharyngolaryngeal pain, pyrexia. SYMLIN dosage: unknown. During the same period patient was treated with HEPATITIS B VACCINE. Patient recovered.
Symlin Side Effects Report #5283593-4
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 03, 2006. Male patient, 66 years of age, weighting 225.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose decreased, dysgeusia, tremor, weight decreased. SYMLIN dosage: unknown. During the same period patient was treated with HUMALOG, LANTUS. Patient recovered.
Symlin Side Effects Report #5283594-6
Consumer or non-health professional from UNITED STATES reported SYMLIN problem on Oct 03, 2006. Male patient, 55 years of age, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: blood glucose increased. SYMLIN dosage: unknown. During the same period patient was treated with BYETTA, INSULIN R U, LANTUS. Patient recovered.
Symlin Side Effects Report #5283614-9
SYMLIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 04, 2006. Female patient, 64 years of age, weighting 217.0 lb, was diagnosed with diabetes mellitus non-insulin-dependent and was treated with SYMLIN. After drug was administered, patient experienced the following problems/side effects: constipation, dysgeusia. SYMLIN dosage: unknown. During the same period patient was treated with LANTUS, APIDRA. Patient recovered.
Showing 1-50 of 836 Next >
Drug Information: Pramlintide Injection
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a605031.html
(pram' lin tide)IMPORTANT WARNING:
| You will use pramlintide with mealtime insulin to control your blood sugar levels. When you use insulin, there is a chance that you will experience hypoglycemia (low blood sugar). This risk may be greater during the first 3 hours after you inject pramlintide, especially if you have Type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood). You may harm yourself or others if your blood sugar drops while you are involved in an activity that requires you to be alert or to think clearly. Do not drive a car or use heavy machinery until you know how pramlintide affects your blood sugar. Talk to your doctor about what other activities you should avoid while you are using pramlintide.Tell your doctor if you have had diabetes for a long time, if you have diabetic nerve disease, if you cannot tell when your blood sugar is low, and if you needed medical treatment for hypoglycemia several times in the past 6 months. Also tell your doctor if you are taking any of the following medications: angiotensin converting enzyme (ACE) inhibitors used to treat high blood pressure, heart disease, or diabetic kidney disease; beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); clonidine (Catapres); disopyramide (Norpace); fenofibrate (Lofibra, Tricor); fluoxetine (Prozac, Sarafem); gemfibrozil (Lopid); guanethidine (Ismelin); other medications for diabetes; monoamine oxidase (MAO) inhibitors such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl), and tranylcypromine (Parnate); pentoxifylline (Trental); propoxyphene (Darvon); reserpine (Serpalan, Serpasil); salicylate pain relievers such as aspirin; and sulfonamide antibiotics such as trimethoprim/sulfamethoxazole (Bactrim, Septra).While you are using pramlintide, you must measure your blood sugar before and after every meal and at bedtime. You also will need to see or talk to your doctor often, and frequently change your doses of pramlintide and insulin according to your doctor's directions. Tell your doctor if you think that it will be difficult for you to do these things, if you have had difficulty checking your blood sugar or using your insulin correctly in the past, or if you find it difficult to manage your treatment after you start using pramlintide.Your doctor will decrease your dose of insulin when you start using pramlintide. Your doctor will start you on a low dose of pramlintide and will gradually increase your dose. Call your doctor right away if you have an upset stomach during this time; your dose may need to be changed or you may have to stop using pramlintide. Your doctor will probably change your dose of insulin once you are using a dose of pramlintide that is right for you. Follow all of these directions carefully and ask your doctor or pharmacist right away if you are not sure how much insulin or pramlintide you should use.The risk of hypoglycemia may be greater in certain situations. Call your doctor if you plan to be more active than usual. If you have any of the following conditions you should not use pramlintide and should call your doctor to find out what to do: you plan to skip a meal.you plan to eat a meal with less than 250 calories or 30 grams of carbohydrates.you cannot eat because you are sick.you cannot eat because you are scheduled for surgery or a medical test.your blood sugar is very low before a meal.Alcohol may cause a decrease in blood sugar. Ask your doctor about the safe use of alcoholic beverages while you are using pramlintide.Call your doctor right away if your blood sugar is lower than normal or if you have any of the following symptoms of low blood sugar: hunger, headache, sweating, shaking of a part of your body that you cannot control, irritability, difficulty concentrating, loss of consciousness, coma, or a seizure. Be sure that you always have a fast acting source of sugar such as hard candy, juice, glucose tablets, or glucagon available to treat hypoglycemia.Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with pramlintide and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also obtain the Medication Guide from the FDA website: http://www.fda.gov. |
Why is this medication prescribed?
Pramlintide is used with mealtime insulin to control blood sugar levels in people who have diabetes. Pramlintide is only used to treat patients whose blood sugar could not be controlled by insulin or insulin and an oral medication for diabetes. Pramlintide is in a class of medications called antihyperglycemics. It works by slowing the movement of food through the stomach. This prevents blood sugar from rising too high after a meal, and may decrease appetite and cause weight loss.
How should this medicine be used?
Pramlintide comes as a solution (liquid) to inject subcutaneously (just under the skin). It is usually injected several times a day, before each meal that includes at least 250 calories or 30 grams of carbohydrate. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use pramlintide exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
Pramlintide controls diabetes but does not cure it. Continue to use pramlintide even if you feel well. Do not stop using pramlintide without talking to your doctor. If you do stop using pramlintide for any reason, do not start using it again without talking to your doctor.
Use a U-100 insulin syringe to inject pramlintide. It is best to use the 0.3-mL size. Use the table in the medication guide to find the number of insulin syringe units that matches your prescribed dose (in micrograms [mcg]) of pramlintide. Ask your doctor or pharmacist if you are not sure how many syringe units of medication you will need to inject.
Use a new syringe and needle for each injection. Do not mix pramlintide and insulin in the same syringe, and do not use the same syringe or needle to inject pramlintide and insulin one after another. Throw away your needle and syringe in a puncture-resistant container that is out of the reach of children. Talk to your doctor or pharmacist about how to throw away the puncture-resistant container.
You can inject pramlintide anywhere on your stomach or thigh. Do not inject pramlintide into your arm. Choose a different spot to inject pramlintide every day. Be sure that the spot you choose is more than 2 inches away from the spot where you will inject insulin.
You should inject pramlintide under the skin the same way that you inject insulin. Allow the vial of pramlintide to warm to room temperature before you inject the medication. Look at the liquid in the vial before you inject it, and do not use it if it is cloudy. If you have questions about injecting pramlintide, ask your doctor or pharmacist.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before using pramlintide,
- tell your doctor and pharmacist if you are allergic to pramlintide, any other medications, or metacresol.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: antihistamines; certain antidepressants ('mood elevators') called tricyclic antidepressants; certain medications to treat asthma, diarrhea, lung disease, mental illness, motion sickness, overactive bladder, pain, Parkinson's disease, stomach or intestinal cramps, ulcers, and upset stomach; cisapride (Propulsid); laxatives; metoclopramide (Reglan); and stool softeners. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking a medication for pain such as acetaminophen (Tylenol), take it at least 1 hour before or 2 hours after you use pramlintide.
- tell your doctor if you have or have ever had gastroparesis (slowed movement of food from the stomach to the small intestine) and if you are being treated with dialysis (treatment to clean the blood outside the body when the kidneys are not working well).
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using pramlintide, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using pramlintide.
What special dietary instructions should I follow?
Your doctor, dietitian, or diabetes educator will help you create a meal plan that works for you. Follow the meal plan carefully.
What should I do if I forget a dose?
Skip the missed dose and use your usual dose of pramlintide before your next major meal. Do not use a double dose to make up for a missed one.
What side effects can this medication cause?
Pramlintide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- redness, swelling, bruising, or itching in the place where you injected pramlintide
- loss of appetite
- stomach pain
- indigestion
- upset stomach
- excessive tiredness
- dizziness
- coughing
- sore throat
- joint pain
Some side effects can be serious. If you experience any of the symptoms listed in the IMPORTANT WARNING section, call your doctor immediately.
Pramlintide may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Keep unopened vials of pramlintide in the refrigerator, but do not freeze them. Throw away any vials that were frozen or exposed to heat. You may store opened vials of pramlintide in the refrigerator or at room temperature, and you must use them within 28 days. Throw away any medication left in an opened vial after 28 days and any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- upset stomach
- vomiting
- diarrhea
- dizziness
- flushing
What other information should I know?
Do not let anyone else use your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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