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Tavegyl Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Adverse Event (7364498-1)
on Mar 08, 2011 Female from SWEDEN , 23 years of age, was treated with Tavegyl. Directly after, patient experienced the unwanted or unexpected Tavegyl side effects: adverse event. Tavegyl dosage: N/A.
Associated medications used:
  • Pulmicort
  • Tradolan
  • Bricanyl
  • Singulair
  • Diazepam
  • Nozinan
  • Flunitrazepam
  • Zolpidem Tartrate
Patient was hospitalized.

Liver Disorder (7211529-5)
Patient was taking Tavegyl. Patient felt the following Tavegyl side effects: liver disorder on Dec 27, 2010 from JAPAN Additional patient health information: Male , 48 years of age, . Tavegyl dosage: Unk, Unk.

Caesarean Section, Premature Labour (7062281-8)
Adverse event was reported on Jul 08, 2009 by a Female taking Tavegyl (nch) (Dosage: 2 Mg, Unk) was diagnosed with
  • prophylaxis
  • cervix carcinoma
and. Location: SWITZERLAND , 32 years of age, weighting 165.3 lb, After Tavegyl was administered, patient encountered several Tavegyl side effects: caesarean section, premature labour.
Multiple concurrent drugs taken:
  • Cisplatin (140 Mg)
  • Paclitaxel (330 Mg)
  • Dexamethasone (20 Mg)
  • Zofran (8 Mg)
  • Zofran (8 Mg, Qd)
  • Zofran
  • Zantic (50 Mg)
  • Celestone/sch/ (12 Mg)


Hyperventilation, Palpitations, Panic Disorder (6872146-X)
on Jul 15, 2010 Female from JAPAN , weighting 127.9 lb, was treated with Tavegyl (nch). Directly after, patient experienced the unwanted or unexpected Tavegyl side effects: hyperventilation, palpitations, panic disorder. Tavegyl (nch) dosage: 1 Mg, Qd.
Associated medications used:
  • Lorazepam (0.5 Mg, Bid)
  • Paxil (10 Mg, Qd)
  • Talion (10 Mg, Bid)
  • Meilax (Unk, Unk)
  • Lorazepam (Unk, Unk)
Patient was hospitalized.


Hyperventilation, Palpitations, Panic Disorder (6861159-X)
on Jun 17, 2010 Female from JAPAN , weighting 127.9 lb, was treated with Tavegyl (nch). Patient felt the following Tavegyl side effects: hyperventilation, palpitations, panic disorder. Tavegyl (nch) dosage: 1 Mg, Qd.
Multiple prescriptions taken:
  • Lorazepam (0.5 Mg, Bid)
  • Paxil (10 Mg, Qd)
  • Talion (10 Mg, Bid)
  • Meilax (Unk, Unk)
  • Lorazepam (Unk, Unk)
Patient was hospitalized.

Hyperventilation, Palpitations, Panic Disorder (6803885-4)
Patient was taking Tavegyl (nch). After Tavegyl was administered, patient encountered several Tavegyl side effects: hyperventilation, palpitations, panic disorder on Jun 17, 2010 from JAPAN Additional patient health information: Female , weighting 127.9 lb, . Tavegyl (nch) dosage: 1 Mg, Qd.
Multiple concurrent drugs taken:
  • Lorazepam (0.5 Mg, Bid)
  • Paxil (10 Mg, Qd)
  • Talion (10 Mg, Bid)
  • Meilax (Unk, Unk)
  • Lorazepam (Unk, Unk)
Patient was hospitalized.

Cardiac Failure, Oedema (6791290-9)
Adverse event was reported on Jun 18, 2010 by a Female taking Tavegyl (nch) (Dosage: 2 Mg, Qd) was diagnosed with
  • pruritus
and. Location: JAPAN , 86 years of age, Directly after, patient experienced the unwanted or unexpected Tavegyl side effects: cardiac failure, oedema.
Associated medications used:
  • Slow-fe (nch) (50 Mg, Qd)
  • Allelock (5 Mg, Qd)
  • Lanirapid (0.05 Mg, Qd)
  • Lasix (40 Mg, Qd)
  • Aldactone (2 Mg, Qd)
  • Aldactone (4 Mg, Qd)
  • Denopamine (10 Mg, Qd)
  • Denopamine (20 Mg, Qd)


Cardiac Failure, Oedema (6791285-5)
on Jun 16, 2010 Female from JAPAN , 86 years of age, was diagnosed with
  • pruritus
and was treated with Tavegyl (nch). Patient felt the following Tavegyl side effects: cardiac failure, oedema. Tavegyl (nch) dosage: 2 Mg, Qd.
Multiple prescriptions taken:
  • Slow-fe (nch) (50 Mg, Qd)
  • Allelock (5 Mg, Qd)
  • Lanirapid (0.05 Mg, Qd)
  • Lasix (40 Mg, Qd)
  • Aldactone (2 Mg, Qd)
  • Denopamine (10 Mg, Qd)
  • Warfarin (1 Mg, Qd)
  • Urinorm (50 Mg, Qd)


Congenital Eye Disorder, Cryptophthalmos (6786952-3)
on Jun 17, 2010 Female from JAPAN , weighting 6.61 lb, was treated with Tavegyl (nch). After Tavegyl was administered, patient encountered several Tavegyl side effects: congenital eye disorder, cryptophthalmos. Tavegyl (nch) dosage: Unk, Unk.
Multiple concurrent drugs taken:
  • Lorazepam (Unk, Unk)
  • Paxil (Unk, Unk)
  • Talion (Unk, Unk)


Cardiac Failure, Oedema (6775747-2)
Patient was taking Tavegyl (nch). Directly after, patient experienced the unwanted or unexpected Tavegyl side effects: cardiac failure, oedema on Jun 10, 2010 from JAPAN Additional patient health information: Female , 86 years of age, was diagnosed with
  • pruritus
and. Tavegyl (nch) dosage: Unk,unk.

Nausea, Pain, Pruritus, Urticaria (6498799-6)
Adverse event was reported on Dec 04, 2009 by a Female taking Tavegyl (nch) (Dosage: Unk, Unk) was diagnosed with
  • urticaria
  • influenza
and. Location: SWEDEN , child 6 years of age, Patient felt the following Tavegyl side effects: nausea, pain, pruritus, urticaria.

Anaphylactoid Reaction, Burning Sensation, Flushing, Rash, Syncope (6239752-7)
on Jun 12, 2009 Female from SWITZERLAND , 49 years of age, was treated with Tavegyl (nch) (clemastine Hydrogen Fumarate). After Tavegyl was administered, patient encountered several Tavegyl side effects: anaphylactoid reaction, burning sensation, flushing, rash, syncope. Tavegyl (nch) (clemastine Hydrogen Fumarate) dosage: N/A.
Multiple concurrent drugs taken:
  • Venofer (300 Mg, Qd, Intravenous)
  • Venofer (300 Mg, Qd, Intravenous)
  • Solu-cortef
  • Metoprolol Succinate
  • Lisinopril
  • Progesterone
  • Estrogens (no Ingredients/substances)


Agranulocytosis, Alanine Aminotransferase Increased, Basophil Count Increased, Blood Lactate Dehydrogenase Increased, Febrile Neutropenia, Hordeolum, Leukopenia, Lymphocyte Count Increased, Lymphocyte Stimulation Test Positive (5835270-6)
on Jul 18, 2008 Male from JAPAN , 59 years of age, weighting 145.5 lb, was diagnosed with
  • bronchitis
and was treated with Tavegyl (clemastine Hydrogen Fumarate). Directly after, patient experienced the unwanted or unexpected Tavegyl side effects: agranulocytosis, alanine aminotransferase increased, basophil count increased, blood lactate dehydrogenase increased, febrile neutropenia, hordeolum, leukopenia, lymphocyte count increased, lymphocyte stimulation test positive. Tavegyl (clemastine Hydrogen Fumarate) dosage: 0.5 G Daily, Oral.
Associated medications used:
  • Theo-dur (2 Df Daily, Oral)
  • Clarithromycin (2 Df Daily, Oral)
  • Mucosta (rebamipide) (3 Df Daily, Oral)
  • Asverin (tipepidine Hibenzate) (0.3 G Daily, Oral)
  • Procaterol Hcl (0.2 G Daily, Oral)
  • Seltepnon (teprenone) (1 G Daily, Oral)
Patient was hospitalized.

Enzyme Abnormality, Hot Flush, Loss Of Consciousness, Nausea, Pupil Fixed, Respiratory Arrest, Respiratory Failure (5220778-7)
Patient was taking Tavegyl (nch) (clemastine Hydrogen Fumarate) Ampoule. Patient felt the following Tavegyl side effects: enzyme abnormality, hot flush, loss of consciousness, nausea, pupil fixed, respiratory arrest, respiratory failure on Jan 12, 2007 from GERMANY Additional patient health information: Male , 72 years of age, weighting 152.1 lb, . Tavegyl (nch) (clemastine Hydrogen Fumarate) Ampoule dosage: 2.68 Mg, Once/single, Intravenous.
Multiple prescriptions taken:
  • Solu-decortin-h (prednisolone Sodium Succinate) (Intravenous)
  • Paclitaxel


Anaphylactic Reaction, Feeling Hot, Hyperhidrosis, Malaise, Paraesthesia, Pulse Absent, Shock (5141048-1)
Adverse event was reported on Sep 08, 2006 by a Male taking Tavegyl (nch) (clemastine Hydrogen Fumarate) Tablet (Dosage: 1 Mg, Once/single, Oral) was diagnosed with
  • pruritus
and. Location: JAPAN , 25 years of age, After Tavegyl was administered, patient encountered several Tavegyl side effects: anaphylactic reaction, feeling hot, hyperhidrosis, malaise, paraesthesia, pulse absent, shock.
Multiple concurrent drugs taken:
  • Veen D (calcium Chloride Dihydrate, Glucose, Potassium Chloride, Sodiu
Patient was hospitalized.

Feeling Hot, Hyperhidrosis, Malaise, Pulse Absent, Shock (5102703-2)
on Aug 08, 2006 Male from JAPAN , 25 years of age, was diagnosed with
  • pruritus
and was treated with Tavegyl (nch) (clemastine Hydrogen Fumarate) Tablet. Directly after, patient experienced the unwanted or unexpected Tavegyl side effects: feeling hot, hyperhidrosis, malaise, pulse absent, shock. Tavegyl (nch) (clemastine Hydrogen Fumarate) Tablet dosage: 1 Mg, Once/single, Oral.
Associated medications used:
  • Veen D (calcium Chloride Dihydrate, Glucose, Potassium Chloride, Sodiu
Patient was hospitalized.

Feeling Hot, Hyperhidrosis, Malaise, Pain, Pruritus, Pulse Absent, Shock, Sunburn (5087228-5)
on Aug 08, 2006 Male from JAPAN , 25 years of age, was diagnosed with
  • pruritus
and was treated with Tavegyl (nch) (clemastine Hydrogen Fumarate) Tablet. Patient felt the following Tavegyl side effects: feeling hot, hyperhidrosis, malaise, pain, pruritus, pulse absent, shock, sunburn. Tavegyl (nch) (clemastine Hydrogen Fumarate) Tablet dosage: 1 Mg, Once/single, Oral.
Multiple prescriptions taken:
  • Veen D(calcium Chloride Dihydrate, Glucose, Potassium Chloride, Sodium (Infusion)
Patient was hospitalized.

Bradycardia (4758730-8)
Patient was taking Tavegyl (nch) (clemastine Hydrogen Fumarate) Tablet. After Tavegyl was administered, patient encountered several Tavegyl side effects: bradycardia on Aug 19, 2005 from SWITZERLAND Additional patient health information: Male , 68 years of age, was diagnosed with
  • angioneurotic oedema
and. Tavegyl (nch) (clemastine Hydrogen Fumarate) Tablet dosage: 1 Mg, Bid, Oral.
Multiple concurrent drugs taken:
  • Metoprolol Succinate (25 Mg, Qd, Oral)
  • Prednisone
  • Enalapril Maleate
  • Aspirin
  • Plavix
  • Nexium
  • Atacand
  • Simcora (simvastatin)


Toxic Epidermal Necrolysis (4726038-2)
Adverse event was reported on Jul 14, 2005 by a Male taking Tavegyl (nch) (clemastine Hydrogen Fumarate) (Dosage: Oral) was diagnosed with
  • urticaria
and. Location: JAPAN , 31 years of age, Directly after, patient experienced the unwanted or unexpected Tavegyl side effects: toxic epidermal necrolysis.
Associated medications used:
  • Atarax
  • Talion (bepotastine Besialte)
Patient was hospitalized.

Toxic Epidermal Necrolysis (4686804-9)
on May 24, 2005 Male from , 31 years of age, was diagnosed with
  • urticaria
and was treated with Tavegyl (nch) (clemastine Hydrogen Fumarate). Patient felt the following Tavegyl side effects: toxic epidermal necrolysis. Tavegyl (nch) (clemastine Hydrogen Fumarate) dosage: Oral.
Multiple prescriptions taken:
  • Atarax
  • Talion (bepotastine Besilate)
Patient was hospitalized.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Tavegyl Information

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