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Review Tigecycline Safety Reports submitted to FDA

Total Tigecycline reports: 57.
Tigecycline FDA safety alerts: No.
Reported deaths: 21    Reported hospitalizations: 24.
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FDA Reported Tigecycline Side Effects: renal failure acute, nausea, multi-organ failure, dehydration, aspartate aminotransferase increased, alanine aminotransferase increased, abdominal abscess, vomiting, renal tubular necrosis, diarrhoea, jaundice.
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Tigecycline Side Effects Report #5650314-2
Pharmacist from UNITED STATES reported TIGECYCLINE problem on Mar 04, 2008. Male patient, 64 years of age, weighting 154.6 lb, was diagnosed with infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: international normalised ratio fluctuation. TIGECYCLINE dosage: 100 MG ONCE IV. Patient was hospitalized and became disabled. Patient recovered.

Tigecycline Side Effects Report #5651466-0
TIGECYCLINE problem was reported by a Physician from FINLAND on Mar 10, 2006. Male patient, 24 years of age, was diagnosed with stenotrophomonas infection, pneumonia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: respiratory failure. TIGECYCLINE dosage: unknown. Patient died.

Tigecycline Side Effects Report #5653833-8
Physician from AUSTRALIA reported TIGECYCLINE problem on June 21, 2007. Male patient, weighting 194.0 lb, was diagnosed with enterococcal sepsis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: aplastic anaemia, fungal infection, haemorrhage, lung infection, multi-organ failure. TIGECYCLINE dosage: 100 MG LOADING DOSE, THEN 50 MG EVERY 12 HOURS. Patient was hospitalized. Patient died on 04/24/2006.

Tigecycline Side Effects Report #5662028-3
TIGECYCLINE problem was reported by a Health Professional from SPAIN on Mar 10, 2008. Male patient, 48 years of age, was diagnosed with pneumonia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: lung infection pseudomonal. TIGECYCLINE dosage: unknown. During the same period patient was treated with AMPHOTERICIN B, AMIKACIN, TAZOCEL. Patient recovered.

Tigecycline Side Effects Report #5662436-0
Physician from UNITED STATES reported TIGECYCLINE problem on Mar 05, 2008. Male patient, weighting 214.2 lb, was diagnosed with abdominal infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: abdominal abscess, thrombocythaemia. TIGECYCLINE dosage: 100 MG LOADING DOSE; THEN 50 MG EVERY 12 HOURS. During the same period patient was treated with ERTAPENEM. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5663234-4
TIGECYCLINE problem was reported by a Pharmacist from UNITED STATES on Mar 11, 2008. Female patient, 64 years of age, was diagnosed with device related infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, aspartate aminotransferase increased, blood amylase increased, blood calcium decreased, gastrointestinal inflammation, haemoglobin decreased, lipase increased, nausea, retroperitoneal effusion. TIGECYCLINE dosage: 50 MG Q12H IV. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5672142-4
Physician from UNITED STATES reported TIGECYCLINE problem on Mar 12, 2008. Male patient, weighting 170.2 lb, was diagnosed with cellulitis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: clostridium difficile colitis. TIGECYCLINE dosage: unknown. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5672166-7
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Mar 11, 2008. Male patient, weighting 214.2 lb, was diagnosed with abdominal infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: abdominal abscess, thrombocythaemia. TIGECYCLINE dosage: 100 MG LOADING DOSE; THEN 50 MG EVERY 12 HOURS. During the same period patient was treated with ERTAPENEM. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5675291-X
Health Professional from SPAIN reported TIGECYCLINE problem on Mar 10, 2008. Female patient, 66 years of age, was diagnosed with pneumonia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hyperbilirubinaemia, septic shock, thrombocytopenia. TIGECYCLINE dosage: unknown. During the same period patient was treated with VANCOMYCIN, COLISTIN SULPHATE. Patient died on 06/16/2007.

Tigecycline Side Effects Report #5675317-3
TIGECYCLINE problem was reported by a Health Professional from SPAIN on Mar 10, 2008. Male patient, 72 years of age, was diagnosed with peritonitis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: lung infection pseudomonal. TIGECYCLINE dosage: unknown. During the same period patient was treated with COLISTIN SULPHATE, AMIKACIN. Patient died on 05/16/2007.

Tigecycline Side Effects Report #5675318-5
Health Professional from SPAIN reported TIGECYCLINE problem on Mar 10, 2008. Male patient, 61 years of age, was diagnosed with pneumonia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: lung infection pseudomonal. TIGECYCLINE dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, COLISTIN SULPHATE, LINEZOLID. Patient died on 05/14/2007.

Tigecycline Side Effects Report #5675320-3
TIGECYCLINE problem was reported by a Health Professional from SPAIN on Mar 10, 2008. Female patient, 41 years of age, was diagnosed with peritonitis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: vomiting. TIGECYCLINE dosage: unknown. During the same period patient was treated with CEFTAZIDIME. Patient died on 04/29/2007.

Tigecycline Side Effects Report #5680661-X
Physician from UNITED STATES reported TIGECYCLINE problem on Mar 21, 2008. Male patient, weighting 170.2 lb, was diagnosed with cellulitis, constipation, hypertension, medical diet, heart rate, atrial fibrillation and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: diarrhoea. TIGECYCLINE dosage: unknown. During the same period patient was treated with SENNA, DOCUSATE, METOPROLOL TARTRATE, CALCIUM WITH VITAMIN D, DIGOXIN, EPOETIN ALFA, BISACODYL, COUMADIN. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5682216-X
TIGECYCLINE problem was reported by a Physician from GREECE on Mar 18, 2008. Male patient, 75 years of age, was diagnosed with soft tissue infection, klebsiella bacteraemia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: gastrointestinal haemorrhage, klebsiella bacteraemia, septic shock. TIGECYCLINE dosage: unknown. Patient died.

Tigecycline Side Effects Report #5610865-3
Physician from UNITED KINGDOM reported TIGECYCLINE problem on Jan 23, 2008. Male patient, 79 years of age, was diagnosed with peritonitis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: clostridial infection. TIGECYCLINE dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, VANCOMYCIN, CEFTRIAXONE. Patient recovered.

Tigecycline Side Effects Report #5610866-5
TIGECYCLINE problem was reported by a Physician from UNITED KINGDOM on Jan 23, 2008. Female patient, 73 years of age, was diagnosed with abdominal abscess and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: clostridial infection, pseudomembranous colitis. TIGECYCLINE dosage: unknown. During the same period patient was treated with VANCOMYCIN, CIPROFLOXACIN, METRONIDAZOLE. Patient recovered.

Tigecycline Side Effects Report #5610874-4
Physician from UNITED KINGDOM reported TIGECYCLINE problem on Jan 23, 2008. Male patient, 44 years of age, was diagnosed with appendicitis perforated and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: clostridial infection. TIGECYCLINE dosage: unknown. During the same period patient was treated with GENTAMICIN SULPHATE, METRONIDAZOLE, CEFOXITIN. Patient recovered.

Tigecycline Side Effects Report #5610875-6
TIGECYCLINE problem was reported by a Physician from UNITED KINGDOM on Jan 23, 2008. Male patient, 23 years of age, was diagnosed with abdominal injury, pneumonia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: clostridial infection. TIGECYCLINE dosage: unknown. During the same period patient was treated with VANCOMYCIN, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN AND TAZOBACTAM, GENTAMICIN SULPHATE, GENTAMICIN SULPHATE, CEFAZOLIN. Patient recovered.

Tigecycline Side Effects Report #5610876-8
Physician from UNITED KINGDOM reported TIGECYCLINE problem on Jan 23, 2008. Male patient, 72 years of age, was diagnosed with staphylococcal infection, bacteraemia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: clostridial infection. TIGECYCLINE dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, RIFAMPICIN, CIPROFLOXACIN, MINOCYCLINE. Patient recovered.

Tigecycline Side Effects Report #5618219-0
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Jan 30, 2008. Male patient, weighting 182.9 lb, was diagnosed with abdominal infection, cardiovascular event prophylaxis, blood cholesterol increased, depression, medical diet, hypertension and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: fungaemia. TIGECYCLINE dosage: 50 MG EVERY 12 HOURS. During the same period patient was treated with ASPIRIN, ATORVASTATIN CALCIUM, CITALOPRAM HYDROBROMIDE, FERROUS SULPHATE, FLOMAX, LISINOPRIL, NIFEDIPINE, NEFAZODONE. Patient recovered.

Tigecycline Side Effects Report #5618878-2
Physician from MEXICO reported TIGECYCLINE problem on Feb 01, 2008. Female patient, weighting 162.3 lb, was diagnosed with diabetic foot infection, type 2 diabetes mellitus and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: blood amylase increased, lipase increased, nausea, vomiting. TIGECYCLINE dosage: unknown. During the same period patient was treated with INSULIN ASPART. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5636652-8
TIGECYCLINE problem was reported by a Physician from MEXICO on Feb 11, 2008. Female patient, weighting 162.3 lb, was diagnosed with diabetic foot infection, type 2 diabetes mellitus and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: blood amylase increased, lipase increased, nausea, vomiting. TIGECYCLINE dosage: unknown. During the same period patient was treated with INSULIN ASPART. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5641691-7
Physician from UNITED STATES reported TIGECYCLINE problem on Feb 15, 2008. Male patient, 51 years of age, was diagnosed with acinetobacter infection, mediastinitis, bacteraemia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: acinetobacter infection. TIGECYCLINE dosage: 100MG LOADING DOSE THEN 50MG EVERY 12 HOURS. During the same period patient was treated with TOBRAMYCIN. Patient died.

Tigecycline Side Effects Report #5641692-9
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Feb 15, 2008. Male patient, 80 years of age, was diagnosed with acinetobacter infection, pneumonia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: acinetobacter infection. TIGECYCLINE dosage: 100MG LOADING DOSE THEN 50MG EVERY 12 HOURS. During the same period patient was treated with CEFEPIME. Patient died.

Tigecycline Side Effects Report #5641693-0
Physician from UNITED STATES reported TIGECYCLINE problem on Feb 15, 2008. Female patient, 59 years of age, was diagnosed with acinetobacter infection, pneumonia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: acinetobacter infection. TIGECYCLINE dosage: 100 MG LOADING DOSE THEN 50MG EVERY 12 HOURS. During the same period patient was treated with COLISTIN SULPHATE, AMIKACIN. Patient died.

Tigecycline Side Effects Report #5641696-6
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Feb 15, 2008. Female patient, 64 years of age, was diagnosed with acinetobacter infection, pneumonia, empyema and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: acinetobacter infection. TIGECYCLINE dosage: 100MG LOADING DOSE THEN 50MG EVERY 12 HOURS. During the same period patient was treated with COLISTIN SULPHATE. Patient died.

Tigecycline Side Effects Report #5641705-4
Physician from UNITED STATES reported TIGECYCLINE problem on Feb 15, 2008. Male patient, 57 years of age, was diagnosed with pneumonia klebsiella, empyema and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pneumonia klebsiella, respiratory failure, sepsis. TIGECYCLINE dosage: 100 MG LOADING DOSE THEN 50MG EVERY 12 HOURS. During the same period patient was treated with GENTAMICIN. Patient died.

Tigecycline Side Effects Report #5641708-X
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Feb 15, 2008. Male patient, 53 years of age, was diagnosed with escherichia infection, bacteraemia and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: escherichia infection. TIGECYCLINE dosage: 100MG LOADING DOSE THEN 50MG EVERY 12 HOURS. Patient recovered.

Tigecycline Side Effects Report #5641709-1
Physician from UNITED STATES reported TIGECYCLINE problem on Feb 15, 2008. Male patient, 44 years of age, was diagnosed with pneumonia klebsiella, mediastinitis, aortic aneurysm and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: aortic rupture, pneumonia klebsiella. TIGECYCLINE dosage: 100MG LOADING DOSE THEN 50MG EVERY 12 HOURS. During the same period patient was treated with COLISTIN SULPHATE, MEROPENEM. Patient died.

Tigecycline Side Effects Report #5603954-0
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Jan 16, 2008. Male patient, weighting 182.9 lb, was diagnosed with abdominal infection, cardiovascular event prophylaxis, blood cholesterol increased, hypertension, medical diet, hypothyroidism, depression and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: fungaemia. TIGECYCLINE dosage: 50 MG EVERY 12 HOURS. During the same period patient was treated with ASPIRIN, ATORVASTATIN, NIFEDIPINE, FERROUS SULPHATE, LEVOTHYROXINE, LISINOPRIL, AMLODIPINE, CITALOPRAM HYDROBROMIDE. Patient recovered.

Tigecycline Side Effects Report #5609332-2
Physician from UNITED STATES reported TIGECYCLINE problem on Sept 18, 2007. Male patient, 57 years of age, was diagnosed with pneumonia, acinetobacter infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pathogen resistance. TIGECYCLINE dosage: 100 MG LOADING DOSE, FOLLOWED BY 25 OR 50 MG/DAY MAINTENANCE DOSE. During the same period patient was treated with COLISTIMETHATE. Patient recovered.

Tigecycline Side Effects Report #5609333-4
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Sept 18, 2007. Female patient, 79 years of age, was diagnosed with acinetobacter bacteraemia, pneumonia, acinetobacter infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pathogen resistance. TIGECYCLINE dosage: 100 MG LOADING DOSE, FOLLOWED BY 25 OR 50 MG/DAY MAINTENANCE DOSE. During the same period patient was treated with COLISTIMETHATE, IMIPENEM. Patient recovered.

Tigecycline Side Effects Report #5510296-0
Physician from UNITED KINGDOM reported TIGECYCLINE problem on Oct 31, 2007. Female patient was diagnosed with acinetobacter infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pathogen resistance. TIGECYCLINE dosage: 100 MG STAT, THEN 50 MG TWICE DAILY. Patient recovered.

Tigecycline Side Effects Report #5501968-2
TIGECYCLINE problem was reported by a Health Professional from UNITED STATES on Oct 23, 2007. Female patient, 53 years of age, was diagnosed with acinetobacter infection, stenotrophomonas infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pathogen resistance. TIGECYCLINE dosage: 100 MG LOADING DOSE, FOLLOWED BY 50 MG EVERY 12 HOURS. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5443659-2
Physician from UNITED STATES reported TIGECYCLINE problem on Aug 29, 2007. Male patient, weighting 271.1 lb, was diagnosed with abdominal abscess, pulmonary embolism, candidiasis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: hepatitis cholestatic, pulmonary embolism. TIGECYCLINE dosage: 100 MG LOADING DOSE, THEN 50 MG EVERY 12 HOURS. During the same period patient was treated with LOVENOX, MYCELEX, COUMADIN. Patient recovered.

Tigecycline Side Effects Report #5451237-4
TIGECYCLINE problem was reported by a Health Professional from UNITED STATES on Sept 04, 2007. Male patient, weighting 251.3 lb, was diagnosed with osteomyelitis, mycobacterium chelonei infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: multi-organ failure, pancreatitis haemorrhagic, pancreatitis necrotising. TIGECYCLINE dosage: unknown. Patient was hospitalized. Patient died on 07/01/2007.

Tigecycline Side Effects Report #5455950-4
Physician from UNITED STATES reported TIGECYCLINE problem on Sept 07, 2007. Male patient, weighting 214.2 lb, was diagnosed with abdominal infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: abdominal abscess, thrombocythaemia. TIGECYCLINE dosage: 100 MG LOADING DOSE; THEN 50 MG EVERY 12 HOURS. During the same period patient was treated with ERTAPENEM. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5464565-3
TIGECYCLINE problem was reported by a Health Professional from UNITED STATES on Sept 11, 2007. Female patient, 49 years of age, was diagnosed with pneumonia klebsiella, empyema, candidiasis, infection, clostridium difficile colitis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pathogen resistance. TIGECYCLINE dosage: 100 MG X 1 DOSE, THEN 50 MG Q12H. During the same period patient was treated with FLUCONAZOLE, VANCOMYCIN, METRONIDAZOLE, CIPROFLOXACIN. Patient was hospitalized. Patient died.

Tigecycline Side Effects Report #5470665-4
Physician from UNITED STATES reported TIGECYCLINE problem on Sept 25, 2007. Male patient, weighting 271.1 lb, was diagnosed with abdominal abscess, pulmonary embolism, candidiasis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: hepatitis cholestatic, pulmonary embolism. TIGECYCLINE dosage: 100 MG LOADING DOSE, THEN 50 MG EVERY 12 HOURS. During the same period patient was treated with LOVENOX, MYCELEX, COUMADIN. Patient recovered.

Tigecycline Side Effects Report #5403741-2
TIGECYCLINE problem was reported by a Physician from UNITED STATES on July 25, 2007. Female patient, weighting 137.0 lb, was diagnosed with bacteraemia, gastrooesophageal reflux disease, deep vein thrombosis, cough, diarrhoea and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: supraventricular tachycardia. TIGECYCLINE dosage: unknown. During the same period patient was treated with PROTONIX, LOVENOX, COUMADIN, TESSALON, IMODIUM. Patient recovered.

Tigecycline Side Effects Report #5410066-8
Physician from UNITED STATES reported TIGECYCLINE problem on July 30, 2007. Male patient, weighting 167.2 lb, was diagnosed with diabetic foot infection, coronary artery disease, hypercholesterolaemia, diabetes mellitus, implantable defibrillator insertion, hypertension and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: blood chloride decreased, blood glucose increased, carbon dioxide increased, dehydration, prothrombin time prolonged, renal failure acute, streptococcal bacteraemia. TIGECYCLINE dosage: unknown. During the same period patient was treated with DILTIAZEM, DIGITEK, FUROSEMIDE, VYTORIN, BUMETANIDE, GLYCOPYRROLATE, COUMADIN, METOPROLOL SUCCINATE. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5416845-5
TIGECYCLINE problem was reported by a Physician from UNITED STATES on Aug 09, 2007. Male patient, weighting 167.2 lb, was diagnosed with diabetic foot infection, coronary artery disease, hypercholesterolaemia, diabetes mellitus, implantable defibrillator insertion, hypertension and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: renal failure acute. TIGECYCLINE dosage: unknown. During the same period patient was treated with DILTIAZEM, DIGITEK, FUROSEMIDE, VYTORIN, BUMETANIDE, GLYCOPYRROLATE, COUMADIN, METOPROLOL SUCCINATE. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5441804-6
Pharmacist from UNITED STATES reported TIGECYCLINE problem on Aug 30, 2007. Female patient, 62 years of age, weighting 160.9 lb, was diagnosed with wound infection staphylococcal and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pancreatitis. TIGECYCLINE dosage: 50 MG Q12HR IV. During the same period patient was treated with ENOXAPARIN, FERROUS SULPHATE, INTERFERON BETA, PROPOFOL, MIDAZOLAM, FENTANYL, BIAFINE, DESIPRAMINE. Patient recovered.

Tigecycline Side Effects Report #5379220-8
TIGECYCLINE problem was reported by a Physician from UNITED STATES on June 26, 2007. Male patient, weighting 214.2 lb, was diagnosed with abdominal infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: abdominal abscess, thrombocythaemia. TIGECYCLINE dosage: 100 MG LOADING DOSE; THEN 50 MG EVERY 12 HOURS. During the same period patient was treated with ERTAPENEM. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5384136-7
Health Professional from AUSTRALIA reported TIGECYCLINE problem on July 06, 2007. Male patient, weighting 132.3 lb, was diagnosed with pneumonia staphylococcal and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: exsanguination, haemoptysis. TIGECYCLINE dosage: unknown. During the same period patient was treated with SALBUTAMOL, MS CONTIN, AMITRIPTYLINE, MORPHINE, GABAPENTIN, DEXAMETHASONE, ESOMEPRAZOLE MAGNESIUM, TEMAZEPAM. Patient died on 01/22/2007.

Tigecycline Side Effects Report #5385750-5
TIGECYCLINE problem was reported by a Health Professional from AUSTRALIA on July 06, 2007. Male patient, weighting 229.3 lb, was diagnosed with pseudomonas infection, septic shock and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: rash erythematous, rash macular. TIGECYCLINE dosage: unknown. During the same period patient was treated with LINEZOLID, HEPARIN, PANTOPRAZOLE, NOREPINEPHRINE, CIPROFLOXACIN, ACYCLOVIR, XIGRIS. Patient recovered.

Tigecycline Side Effects Report #5387574-1
Pharmacist from UNITED STATES reported TIGECYCLINE problem on July 11, 2007. Male patient, weighting 251.3 lb, was diagnosed with mycobacterium chelonei infection, osteomyelitis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: hypotension, hypovolaemia, multi-organ failure, pancreatic atrophy, pancreatitis haemorrhagic, pancreatitis necrotising. TIGECYCLINE dosage: 50MG TWICE DAILY IV. Patient was hospitalized. Patient died on 07/04/2007.

Tigecycline Side Effects Report #5393366-X
TIGECYCLINE problem was reported by a Pharmacist from UNITED STATES on July 18, 2007. Female patient, 51 years of age, was diagnosed with knee operation and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pancreatitis. TIGECYCLINE dosage: 50 MG EVERY 12 HOURS IV. During the same period patient was treated with COZAAR, DYAZIDE, LIPITOR, GABAPENTIN, VICODIN, SYNTHROID, OXYCONTIN, DURAGESIC. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5401305-8
Physician from UNITED STATES reported TIGECYCLINE problem on July 19, 2007. Male patient, weighting 167.2 lb, was diagnosed with diabetic foot infection, coronary artery disease, diabetes mellitus, hypertension, hypercholesterolaemia, implantable defibrillator insertion and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: renal failure acute. TIGECYCLINE dosage: unknown. During the same period patient was treated with DILTIAZEM, GLYCOPYRROLATE, METOPROLOL SUCCINATE, VYTORIN, BUMETANIDE, COUMADIN, DIGITEK. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5403795-3
TIGECYCLINE problem was reported by a Pharmacist from UNITED STATES on July 31, 2007. Male patient, 54 years of age, weighting 60.00 lb, was diagnosed with wound infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: confusional state, pancreatitis acute. TIGECYCLINE dosage: 50MG Q 12HR. Patient recovered.

Tigecycline Side Effects Report #5379220-8
Physician from UNITED STATES reported TIGECYCLINE problem on June 26, 2007. Male patient, weighting 214.2 lb, was diagnosed with abdominal infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: abdominal abscess, thrombocythaemia. TIGECYCLINE dosage: 100 MG LOADING DOSE; THEN 50 MG EVERY 12 HOURS. During the same period patient was treated with ERTAPENEM. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5384136-7
TIGECYCLINE problem was reported by a Health Professional from AUSTRALIA on July 06, 2007. Male patient, weighting 132.3 lb, was diagnosed with pneumonia staphylococcal and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: exsanguination, haemoptysis. TIGECYCLINE dosage: unknown. During the same period patient was treated with SALBUTAMOL, MS CONTIN, AMITRIPTYLINE, MORPHINE, GABAPENTIN, DEXAMETHASONE, ESOMEPRAZOLE MAGNESIUM, TEMAZEPAM. Patient died on 01/22/2007.

Tigecycline Side Effects Report #5385750-5
Health Professional from AUSTRALIA reported TIGECYCLINE problem on July 06, 2007. Male patient, weighting 229.3 lb, was diagnosed with pseudomonas infection, septic shock and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: rash erythematous, rash macular. TIGECYCLINE dosage: unknown. During the same period patient was treated with LINEZOLID, HEPARIN, PANTOPRAZOLE, NOREPINEPHRINE, CIPROFLOXACIN, ACYCLOVIR, XIGRIS. Patient recovered.

Tigecycline Side Effects Report #5387574-1
TIGECYCLINE problem was reported by a Pharmacist from UNITED STATES on July 11, 2007. Male patient, weighting 251.3 lb, was diagnosed with mycobacterium chelonei infection, osteomyelitis and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: hypotension, hypovolaemia, multi-organ failure, pancreatic atrophy, pancreatitis haemorrhagic, pancreatitis necrotising. TIGECYCLINE dosage: 50MG TWICE DAILY IV. Patient was hospitalized. Patient died on 07/04/2007.

Tigecycline Side Effects Report #5393366-X
Pharmacist from UNITED STATES reported TIGECYCLINE problem on July 18, 2007. Female patient, 51 years of age, was diagnosed with knee operation and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: pancreatitis. TIGECYCLINE dosage: 50 MG EVERY 12 HOURS IV. During the same period patient was treated with COZAAR, DYAZIDE, LIPITOR, GABAPENTIN, VICODIN, SYNTHROID, OXYCONTIN, DURAGESIC. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5401305-8
TIGECYCLINE problem was reported by a Physician from UNITED STATES on July 19, 2007. Male patient, weighting 167.2 lb, was diagnosed with diabetic foot infection, coronary artery disease, diabetes mellitus, hypertension, hypercholesterolaemia, implantable defibrillator insertion and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: renal failure acute. TIGECYCLINE dosage: unknown. During the same period patient was treated with DILTIAZEM, GLYCOPYRROLATE, METOPROLOL SUCCINATE, VYTORIN, BUMETANIDE, COUMADIN, DIGITEK. Patient was hospitalized. Patient recovered.

Tigecycline Side Effects Report #5403795-3
Pharmacist from UNITED STATES reported TIGECYCLINE problem on July 31, 2007. Male patient, 54 years of age, weighting 60.00 lb, was diagnosed with wound infection and was treated with TIGECYCLINE. After drug was administered, patient experienced the following problems/side effects: confusional state, pancreatitis acute. TIGECYCLINE dosage: 50MG Q 12HR. Patient recovered.


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