Tnkase Side Effects summary

Total Tnkase reports: 46. View

Tnkase FDA safety alerts: No.

Reported deaths: 22

Reported hospitalizations: 11.

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Recently reported Tnkase Side Effects


Common Tnkase Side Effects
Cerebral haemorrhage 26%
Pneumonia  What is  Pneumonia                                                                                                                                                                                               17%
Cardiogenic shock 13%
Cytolytic hepatitis 13%
Pulmonary haemorrhage 13%
Cerebral haematoma 11%
Multi-organ failure 11%
Anaemia 9%
Overdose 9%
Ventricular fibrillation 9%
Gastric haemorrhage 7%
Renal failure acute 7%
Unresponsive to stimuli 7%
Atelectasis 4%
Cardio-respiratory arrest 4%
Culture urine positive 4%
Fatigue 4%
Haemorrhagic stroke 4%
Hyperthermia 4%
Klebsiella infection 4%
Nausea  What is  Nausea                                                                                                                                                                                                  4%
Pleural effusion 4%
Post procedural complication 4%
Pulmonary thrombosis 4%
Pupil fixed 4%
Renal failure 4%
Thrombolysis 4%
Acute myocardial infarction 2%
Amnesia 2%
Amputation 2%
Angioedema 2%
Arterial repair 2%
Brain herniation 2%
Brain scan abnormal 2%
Cerebrovascular accident 2%
Coma 2%
Convulsion 2%
Coronary artery disease  What is  Coronary artery disease                                                                                                                                                                                 2%
Death 2%
Disease progression 2%
Gastrointestinal disorder 2%
Gastrointestinal haemorrhage 2%
Haematemesis 2%
Haemoglobin decreased 2%
Haemorrhage 2%
Haemorrhagic transformation stroke 2%
Headache  What is  Headache                                                                                                                                                                                                2%
Hemiparesis 2%
Hypertension 2%
Ileus 2%
Injection site haemorrhage 2%
Intracranial haematoma 2%
Intraventricular haemorrhage 2%
Ischaemia 2%
Lethargy 2%
Nosocomial infection 2%
Procedural complication 2%
Pulmonary embolism  What is  Pulmonary embolism                                                                                                                                                                                      2%
Pulse absent 2%
Reperfusion arrhythmia 2%
Respiratory distress 2%
Shock haemorrhagic 2%
Ventricular tachycardia 2%
Vomiting 2%

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Tnkase Side Effects Report #5230493-1
Pharmacist from CANADA reported Tnkase side effect on Jan 26, 2007. Female patient, 70 years of age, weighting 152.1 lb, was treated with Tnkase. After drug was administered, patient experienced the following side effects: amnesia, hemiparesis, intraventricular haemorrhage. Tnkase dosage: unknown. During the same period patient was treated with ASPIRIN, ENOXAPARIN, ATORVASTATIN CALCIUM, NITROGLYCERIN, CLOPIDOGREL BISULPHATE, HEPARIN, METOPOLOL. Patient recovered.



Tnkase Side Effects Report #5248682-9
Tnkase side effect was reported by a Pharmacist from UNITED STATES on Feb 26, 2007. Male patient, 71 years of age, was treated with Tnkase. After drug was administered, patient experienced the following side effects: haemorrhagic transformation stroke. Tnkase dosage: 50 MG OTO IV. During the same period patient was treated with HEPARIN. Patient died.



Tnkase Side Effects Report #5272193-8
Pharmacist from UNITED STATES reported Tnkase side effect on Mar 13, 2007. Female patient was diagnosed with ischaemic stroke and was treated with Tnkase. After drug was administered, patient experienced the following side effects: pulmonary haemorrhage, renal failure, ventricular fibrillation. Tnkase dosage: 0.9 MG/KG, SINGLE, INTRAVENOUS. Patient died.



Tnkase Side Effects Report #5328531-0
Tnkase side effect was reported by a Pharmacist from UNITED STATES on May 17, 2007. Female patient was diagnosed with ischaemic stroke and was treated with Tnkase. After drug was administered, patient experienced the following side effects: haemorrhage, renal failure, ventricular fibrillation. Tnkase dosage: 0.9 MG/KG, SINGLE. Patient died.




Tnkase Side Effects Report #5345549-2
Pharmacist from UNITED STATES reported Tnkase side effect on June 01, 2007. Female patient, weighting 211.6 lb, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Tnkase dosage: 50MG X1 IV. During the same period patient was treated with HEPARIN. Patient died on 05/26/2007.



Tnkase Side Effects Report #5358846-1
Tnkase side effect was reported by a Physician from GERMANY on June 08, 2007. Female patient was diagnosed with peripheral ischaemia and was treated with Tnkase. After drug was administered, patient experienced the following side effects: amputation. Tnkase dosage: 0.25 MG/HR, UNK. During the same period patient was treated with HEPARIN. Patient recovered.



Tnkase Side Effects Report #5358880-1
Physician from GERMANY reported Tnkase side effect on June 08, 2007. Female patient was diagnosed with peripheral ischaemia, thrombosis and was treated with Tnkase. After drug was administered, patient experienced the following side effects: arterial repair. Tnkase dosage: 1.5 MG, UNK. During the same period patient was treated with ABCIXIMAB, HEPARIN. Patient recovered.



Tnkase Side Effects Report #5368413-1
Tnkase side effect was reported by a Pharmacist from UNITED STATES on June 22, 2007. Male patient, 52 years of age, was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: angioedema, cardio-respiratory arrest, convulsion, pulse absent, respiratory distress, ventricular fibrillation. Tnkase dosage: 45MG ONE TIME IV BOLUS. Patient died on 06/18/2007.



Tnkase Side Effects Report #5085489-X
Physician from CANADA reported Tnkase side effect on Aug 03, 2006. Male patient, 62 years of age, weighting 183.0 lb, was diagnosed with myocardial infarction, acute myocardial infarction, diagnostic procedure and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cardiogenic shock, cytolytic hepatitis, multi-organ failure, pneumonia What is  pneumonia. Tnkase dosage: unknown. During the same period patient was treated with ENOXAPARIN, REOPRO, ASPIRIN, CONTRAST MEDIA NOS. Patient recovered.




Tnkase Side Effects Report #5746345-4
Tnkase side effect was reported by a Pharmacist from UNITED STATES on May 20, 2008. Female patient, 45 years of age, weighting 188.0 lb, was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: reperfusion arrhythmia, unresponsive to stimuli, ventricular fibrillation, ventricular tachycardia. Tnkase dosage: 45MG ONCE IV BOLUS. Patient died on 03/19/2008.



Tnkase Side Effects Report #5804522-8
Pharmacist from UNITED STATES reported Tnkase side effect on July 07, 2008. Male patient, 69 years of age, weighting 172.0 lb, was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: acute myocardial infarction, brain herniation, cerebral haemorrhage, coronary artery disease What is  coronary artery disease, lethargy, nausea What is  nausea, procedural complication, pupil fixed, unresponsive to stimuli. Tnkase dosage: 40 MG BOLUS IV BOLUS. Patient died on 05/24/2008.



Tnkase Side Effects Report #5854739-1
Tnkase side effect was reported by a Health Professional from UNITED STATES on Aug 15, 2008. Female patient was diagnosed with coronary arterial stent insertion and was treated with Tnkase. After drug was administered, patient experienced the following side effects: pleural effusion, pulmonary haemorrhage, pulmonary thrombosis. Tnkase dosage: unknown. During the same period patient was treated with INTEGRILIN, LOVENOX. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #5868156-1
Health Professional from GERMANY reported Tnkase side effect on Aug 26, 2008. Female patient was diagnosed with coronary arterial stent insertion and was treated with Tnkase. After drug was administered, patient experienced the following side effects: pleural effusion, pulmonary haemorrhage, pulmonary thrombosis. Tnkase dosage: 50 MG, UNK. During the same period patient was treated with INTEGRILIN, LOVENOX. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #6120117-3
Tnkase side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 11, 2009. Male patient, 76 years of age, was diagnosed with ischaemic stroke and was treated with Tnkase. Tnkase dosage: unknown. Patient died.




Tnkase Side Effects Report #6129343-0
Consumer or non-health professional from UNITED STATES reported Tnkase side effect on Mar 23, 2009. Female patient, 75 years of age, weighting 182.3 lb, was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: hypertension, intracranial haematoma, unresponsive to stimuli. Tnkase dosage: 45 MG ONCE IV. Patient recovered.



Tnkase Side Effects Report #4578763-4
Tnkase side effect was reported by a Pharmacist from on Feb 07, 2005. Male patient, 57 years of age, weighting 187.4 lb, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, cerebral haematoma, cerebral haemorrhage, coma, headache What is  headache, nausea What is  nausea, pupil fixed. Tnkase dosage: 45MG IV X 1. During the same period patient was treated with NITROGLYCERIN, INTEGRILIN, PLAVIX, METOPROLOL, HEPARIN. Patient died on 01/25/2005.



Tnkase Side Effects Report #4595843-8
Physician from reported Tnkase side effect on Feb 15, 2005. Male patient, 62 years of age, weighting 183.0 lb, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cardiogenic shock, cytolytic hepatitis, gastric haemorrhage, multi-organ failure, pneumonia What is  pneumonia, renal failure acute. Tnkase dosage: unknown. During the same period patient was treated with ENOXAPARIN, ABCIXIMAB. Patient recovered.



Tnkase Side Effects Report #4596888-4
Tnkase side effect was reported by a Consumer or non-health professional from on Jan 24, 2005. Female patient, 77 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: anaemia, pneumonia What is  pneumonia. Tnkase dosage: unknown. During the same period patient was treated with ANTIBIOTIC NOS. Patient recovered.



Tnkase Side Effects Report #4596889-6
Consumer or non-health professional from reported Tnkase side effect on Jan 24, 2005. Female patient, 77 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: anaemia, nosocomial infection, pneumonia What is  pneumonia. Tnkase dosage: unknown. Patient recovered.




Tnkase Side Effects Report #4599641-0
Tnkase side effect was reported by a Consumer or non-health professional from on Feb 25, 2005. Female patient, 77 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: anaemia, pneumonia What is  pneumonia. Tnkase dosage: unknown. Patient recovered.



Tnkase Side Effects Report #4599809-3
Consumer or non-health professional from reported Tnkase side effect on Feb 25, 2005. Female patient, 77 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: anaemia, pneumonia What is  pneumonia. Tnkase dosage: unknown. During the same period patient was treated with ANTIBIOTIC NOS. Patient recovered.



Tnkase Side Effects Report #4638329-4
Tnkase side effect was reported by a Health Professional from on Apr 07, 2005. Male patient, 62 years of age, weighting 183.0 lb, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: atelectasis, cardiogenic shock, culture urine positive, cytolytic hepatitis, fatigue, hyperthermia, klebsiella infection, multi-organ failure. Tnkase dosage: unknown. During the same period patient was treated with ENOXAPARIN, ABCIXIMAB, LASIX, CLONAZEPAM, PENMIX, PANTERIC, LOPRESSOR. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #4645480-1
Physician from reported Tnkase side effect on Apr 19, 2005. Male patient, 62 years of age, weighting 183.0 lb, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: atelectasis, cardiogenic shock, culture urine positive, cytolytic hepatitis, fatigue, gastrointestinal haemorrhage, hyperthermia, klebsiella infection. Tnkase dosage: unknown. During the same period patient was treated with ENOXAPARIN, ABCIXIMAB, LASIX, CLONAZEPAM, FESO, PENMIX, PANTERIC, LOPRESSOR. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #4645948-8
Tnkase side effect was reported by a Pharmacist from on Apr 22, 2005. Female patient, 76 years of age, weighting 148.0 lb, was diagnosed with pulmonary embolism What is  pulmonary embolism and was treated with Tnkase. After drug was administered, patient experienced the following side effects: post procedural complication, pulmonary embolism What is  pulmonary embolism, pulmonary haemorrhage. Tnkase dosage: 5 MG INFUSED DIRECTLY TO CLOT SITE IN UPPER LOBE. During the same period patient was treated with WARFARIN, TEMAZEPAM, ARGATROBAN. Patient died.




Tnkase Side Effects Report #4658681-3
Pharmacist from reported Tnkase side effect on May 10, 2005. Male patient, 57 years of age, was diagnosed with acute myocardial infarction, coronary arterial stent insertion and was treated with Tnkase. After drug was administered, patient experienced the following side effects: haematemesis, haemoglobin decreased, ileus, shock haemorrhagic. Tnkase dosage: 40MG ONCE INTRAVENOU. During the same period patient was treated with REOPRO, HEPARIN, ASPIRIN, CLOPIDOGREL BISULPHATE. Patient recovered.



Tnkase Side Effects Report #4685791-7
Tnkase side effect was reported by a Physician from on June 07, 2005. Male patient was diagnosed with cerebrovascular accident and was treated with Tnkase. After drug was administered, patient experienced the following side effects: haemorrhagic stroke, thrombolysis. Tnkase dosage: 4 MG INTRA-ARTERIAL. Patient recovered.



Tnkase Side Effects Report #4685792-9
Physician from reported Tnkase side effect on June 07, 2005. Male patient was diagnosed with cerebrovascular accident and was treated with Tnkase. After drug was administered, patient experienced the following side effects: haemorrhagic stroke, thrombolysis. Tnkase dosage: 5MG, 1 TIME, INTRA-ARTERIAL. Patient died.



Tnkase Side Effects Report #4688551-6
Tnkase side effect was reported by a Physician from on May 10, 2005. Male patient, 62 years of age, weighting 183.0 lb, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cardiogenic shock, cytolytic hepatitis, gastric haemorrhage, multi-organ failure, pneumonia What is  pneumonia, renal failure acute. Tnkase dosage: unknown. During the same period patient was treated with ENOXAPARIN, ABCIXMAB. Patient recovered.



Tnkase Side Effects Report #4693810-7
Physician from reported Tnkase side effect on June 07, 2005. Male patient, 62 years of age, weighting 183.0 lb, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cardiogenic shock, cytolytic hepatitis, gastric haemorrhage, multi-organ failure, pneumonia What is  pneumonia, post procedural complication, renal failure acute. Tnkase dosage: unknown. During the same period patient was treated with ENOXAPARIN, ABCIXIMAB. Patient recovered.




Tnkase Side Effects Report #4708498-6
Tnkase side effect was reported by a Health Professional from UNITED STATES on July 05, 2005. Female patient, child 5 years of age, weighting 156.0 lb, was diagnosed with cerebrovascular accident and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebrovascular accident. Tnkase dosage: 3 MG INTRAARTERIAL. Patient died on 05/06/2005.



Tnkase Side Effects Report #4740411-8
Pharmacist from UNITED STATES reported Tnkase side effect on Jan 10, 2005. Male patient, 44 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haematoma. Tnkase dosage: unknown. During the same period patient was treated with INTEGRILIN, HEPARIN, PLAVIX, ASPIRIN. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #4740414-3
Tnkase side effect was reported by a Physician from UNITED STATES on Jan 11, 2005. Female patient was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Tnkase dosage: 30 MG. During the same period patient was treated with HEPARIN, ASPIRIN. Patient died.



Tnkase Side Effects Report #4740416-7
Pharmacist from UNITED STATES reported Tnkase side effect on Feb 09, 2005. Male patient, 57 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haematoma, cerebral haemorrhage. Tnkase dosage: 45 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with NITROGLYCERIN DRIP, INTEGRILIN, PLAVIX, METOPROLOL TARTRATE, HEPARIN. Patient died on 01/25/2005.



Tnkase Side Effects Report #4740418-0
Tnkase side effect was reported by a Pharmacist from UNITED STATES on Apr 21, 2005. Female patient, 76 years of age, was diagnosed with pulmonary embolism What is  pulmonary embolism and was treated with Tnkase. After drug was administered, patient experienced the following side effects: pulmonary haemorrhage. Tnkase dosage: unknown. Patient died.




Tnkase Side Effects Report #4740419-2
Pharmacist from UNITED STATES reported Tnkase side effect on June 07, 2004. Female patient, 81 years of age, weighting 163.1 lb, was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: injection site haemorrhage. Tnkase dosage: unknown. During the same period patient was treated with DOPAMINE, HEPARIN, MORPHINE. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #4740727-5
Tnkase side effect was reported by a Pharmacist from UNITED STATES on Jan 10, 2005. Male patient, 44 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haematoma. Tnkase dosage: unknown. During the same period patient was treated with INTEGRILIN, HEPARIN, PLAVIX, ASPIRIN. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #4740749-4
Physician from UNITED STATES reported Tnkase side effect on Jan 11, 2005. Female patient was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Tnkase dosage: 30 MG. During the same period patient was treated with HEPARIN, ASPIRIN. Patient died.



Tnkase Side Effects Report #4740751-2
Tnkase side effect was reported by a Pharmacist from UNITED STATES on Feb 09, 2005. Male patient, 57 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haematoma, cerebral haemorrhage. Tnkase dosage: 45 MG, SINGLE, INTRAVENOUS. During the same period patient was treated with NITROGLYCERIN DRIP, INTEGRILIN, PLAVIX, METOPROLOL TARTRATE, HEPARIN. Patient died on 01/25/2005.



Tnkase Side Effects Report #4740753-6
Pharmacist from UNITED STATES reported Tnkase side effect on Apr 21, 2005. Female patient, 76 years of age, was diagnosed with pulmonary embolism What is  pulmonary embolism and was treated with Tnkase. After drug was administered, patient experienced the following side effects: pulmonary haemorrhage. Tnkase dosage: unknown. Patient died.




Tnkase Side Effects Report #4850682-5
Tnkase side effect was reported by a Pharmacist from UNITED STATES on Dec 08, 2005. Male patient, 51 years of age, was diagnosed with myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: brain scan abnormal, cerebral haemorrhage. Tnkase dosage: unknown. During the same period patient was treated with CLOPIDOGREL, ASPIRIN, ENOXAPARIN. Patient was hospitalized. Patient recovered.



Tnkase Side Effects Report #4854100-2
Pharmacist from UNITED STATES reported Tnkase side effect on Nov 30, 2005. Male patient, 76 years of age, weighting 145.5 lb, was diagnosed with ischaemic stroke and was treated with Tnkase. After drug was administered, patient experienced the following side effects: disease progression, ischaemia. Tnkase dosage: 50 MG, SINGLE, INTRAVENOUS. Patient recovered.



Tnkase Side Effects Report #4942593-1
Tnkase side effect was reported by a Pharmacist from UNITED STATES on Feb 24, 2006. Male patient, 67 years of age, was diagnosed with acute myocardial infarction and was treated with Tnkase. After drug was administered, patient experienced the following side effects: gastrointestinal disorder. Tnkase dosage: unknown. Patient recovered.



Tnkase Side Effects Report #4967163-0
Pharmacist from UNITED STATES reported Tnkase side effect on Mar 27, 2006. Female patient, 72 years of age, weighting 154.3 lb, was diagnosed with cerebrovascular accident and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, overdose. Tnkase dosage: unknown. During the same period patient was treated with ACTIVASE. Patient died on 03/03/2006.



Tnkase Side Effects Report #4967181-2
Tnkase side effect was reported by a Pharmacist from UNITED STATES on Mar 27, 2006. Female patient, 72 years of age, weighting 154.3 lb, was diagnosed with cerebrovascular accident and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, overdose. Tnkase dosage: unknown. During the same period patient was treated with ACTIVASE. Patient died on 03/03/2006.



Tnkase Side Effects Report #5041271-0
Pharmacist from UNITED STATES reported Tnkase side effect on June 20, 2006. Female patient, 72 years of age, weighting 154.3 lb, was diagnosed with cerebrovascular accident and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, overdose. Tnkase dosage: unknown. During the same period patient was treated with ACTIVASE. Patient died on 03/03/2006.



Tnkase Side Effects Report #5041293-X
Tnkase side effect was reported by a Pharmacist from UNITED STATES on June 20, 2006. Female patient, 72 years of age, weighting 154.3 lb, was diagnosed with cerebrovascular accident and was treated with Tnkase. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, overdose. Tnkase dosage: unknown. During the same period patient was treated with ACTIVASE. Patient died on 03/03/2006.





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